Endoplasmic reticulum stress is involved in hepatic SREBP-1c activation and lipid accumulation in fructose-fed mice

Toxicology Letters

Volumn 212, Issue 3, 2012, Pages 229-240

  Zhang, Cheng ^a   Chen, Xi ^a   Zhu, Ren Min ^a   Zhang, Ying ^a   Yu, Tao ^a   Wang, Hua ^a   Zhao, Hui ^a   Zhao, Mei ^a   Ji, Yan Li ^a   Chen, Yuan Hua ^a   Meng, Xiu Hong ^a   Wei, Wei ^a   Xu, De Xiang ^a  

^a ANHUI MEDICAL UNIVERSITY   (China)

Author keywords

Endoplasmic reticulum stress; Fructose; Hepatic lipid accumulation; Insulin resistance; Liver; Phenylbutyric acid

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; FATTY ACID SYNTHASE; FRUCTOSE; GLUCOSE REGULATED PROTEIN 78; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; FEMALE; INSULIN RESISTANCE; LIPID LIVER LEVEL; LIPID STORAGE; LIVER; MOUSE; NONALCOHOLIC FATTY LIVER; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; UNFOLDED PROTEIN RESPONSE; UPREGULATION;

ACETYL-COA CARBOXYLASE; ANIMALS; DIETARY CARBOHYDRATES; EIF-2 KINASE; ENDOPLASMIC RETICULUM; FATTY ACID SYNTHETASE COMPLEX; FATTY LIVER; FEMALE; FRUCTOSE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HEAT-SHOCK PROTEINS; LIPID METABOLISM; LIVER; MICE; MICE, INBRED STRAINS; NUCLEAR PROTEINS; PHENYLBUTYRATES; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; STRESS, PHYSIOLOGICAL; TRANSCRIPTION FACTORS;

ANIMALIA; MUS; RODENTIA;

EID: 84862984616     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2012.06.002     Document Type: Article

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