Fructose intake during pregnancy up-regulates the expression of maternal and fetal hepatic sterol regulatory element-binding protein-1c in rats

Endocrine

Volumn 44, Issue 1, 2013, Pages 79-86

  Mukai, Yuuka ^a   Kumazawa, Maya ^a   Sato, Shin ^a  

^a AOMORI UNIVERSITY OF HEALTH AND WELFARE   (Japan)

Author keywords

Fetus; Fructose; Lipid metabolism; Liver; Rat; SREBP 1c

Indexed keywords

ACYL COENZYME A OXIDASE; FATTY ACID SYNTHASE; FRUCTOSE; GLUCOSE; INSULIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; TRIACYLGLYCEROL;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CARBOHYDRATE METABOLISM; CONTROLLED STUDY; FEMALE; FETUS; FETUS WEIGHT; GENE EXPRESSION; GLUCOSE BLOOD LEVEL; HYPERGLYCEMIA; INSULIN BLOOD LEVEL; LIPID METABOLISM; LIVER; MARE; MATERNAL NUTRITION; MATERNAL PLASMA; NONHUMAN; ORGAN WEIGHT; PLACENTA WEIGHT; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; SUGAR INTAKE; UPREGULATION;

ANIMALS; EATING; FEMALE; FETUS; FRUCTOSE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; LIVER; MATERNAL NUTRITIONAL PHYSIOLOGICAL PHENOMENA; MOTHERS; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RATS; RATS, WISTAR; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; UP-REGULATION;

EID: 84881123371     PISSN: 1355008X     EISSN: 15590100     Source Type: Journal    
DOI: 10.1007/s12020-012-9815-8     Document Type: Article

References (41)

1. S. Vuilleumier, Worldwide production of high-fructose syrup and crystalline fructose. Am. J. Clin. Nutr. 58, 733S-736S (1993)
2. S.W. Rizkalla, Health implications of fructose consumption: a review of recent data. Nutr. Metab. 7, 82 (2010)
3. K.L. Stanhope, P.J. Havel, Fructose consumption: recent results and their potential implications. Ann. N. Y. Acad. Sci. 1190, 15-24 (2010)
4. S.M. Hofmann, M.H. Tschop, Dietary sugars: a fat difference. J. Clin. Invest. 119, 1089-1092 (2009)
5. R.J. Johnson, M.S. Segal, Y. Sautin, T. Nakagawa, D.I. Feig, D.H. Kang, M.S. Gersch, S. Benner, L.G. Sanchez-Lozada, Potential role of sugar (fructose) in the epidemic of hypertension, obesity and the metabolic syndrome, diabetes, kidney disease, and cardiovascular disease. Am. J. Clin. Nutr. 86, 899-906 (2007)
6. A.W. Thorburn, L.H. Storlien, A.B. Jenkins, S. Khouri, E.W. Kraegen, Fructose-induced in vivo insulin resistance and elevated plasma triglyceride levels in rats. Am. J. Clin. Nutr. 49, 1155-1163 (1989)
7. J. Luo, S.W. Rizkalla, M. Lerer-Metzger, J. Boillot, A. Ardeleanu, F. Bruzzo, A. Chevalier, G. Slama, A fructose-rich diet decreases insulin-stimulated glucose incorporation into lipids but not glucose transport in adipocytes of normal and diabetic rats. J. Nutr. 125, 164-171 (1995)
8. R.M. Bezerra, M. Ueno, M.S. Silva, D.Q. Tavares, C.R. Carvalho, M.J. Saad, A high fructose diet affects the early steps of insulin action in muscle and liver of rats. J. Nutr. 130, 1531-1535 (2000)
9. K.L. Stanhope, J.M. Schwarz, N.L. Keim, S.C. Griffen, A.A. Bremer, J.L. Graham, B. Hatcher, C.L. Cox, A. Dyachenko, W. Zhang, J.P. McGahan, A. Seibert, R.M. Krauss, S. Chiu, E.J. Schaefer, M. Ai, S. Otokozawa, K. Nakajima, T. Nakano, C. Beysen, M.K. Hellerstein, L. Berglund, P.J. Havel, Consuming fructose-sweetened, not glucose-sweetened, beverages increases visceral adiposity and lipids and decreases insulin sensitivity in overweight/obese humans. J. Clin. Invest. 119, 1322-1334 (2009)
10. K.L. Teff, S.S. Elliott, M. Tschop, T.J. Kieffer, D. Rader, M. Heiman, R.R. Townsend, N.L. Keim, D. D'Alessio, P.J. Havel, Dietary fructose reduces circulating insulin and leptin, attenuates postprandial suppression of ghrelin, and increases triglycerides in women. J. Clin. Endocrinol. Metab. 89, 2963-2972 (2004)
11. N.K. Pollock, V. Bundy, W. Kanto, C.L. Davis, P.J. Bernard, H. Zhu, B. Gutin, Y. Dong, Greater fructose consumption is associated with cardiometabolic risk markers and visceral adiposity in adolescents. J. Nutr. 142, 251-257 (2012)
12. D.S. Ludwig, K.E. Peterson, S.L. Gortmaker, Relation between consumption of sugar-sweetened drinks and childhood obesity: a prospective, observational analysis. Lancet 357, 505-508 (2001)
13. S.C. Langley, A.A. Jackson, Increased systolic blood pressure in adult rats induced by fetal exposure to maternal low protein diets. Clin. Sci. 86, 217-222 (1994)
14. G. Cambonie, B. Comte, C. Yzydorczyk, T. Ntimbane, N. Germain, N.L. Le, P. Pladys, C. Gauthier, I. Lahaie, D. Abran, J.C. Lavoie, A.M. Nuyt, Antenatal antioxidant prevents adult hypertension, vascular dysfunction, and microvascular rarefaction associated with in utero exposure to a low-protein diet. Am. J. Physiol. Regul. Integr. Comp. Physiol. 292, R1236-R1245 (2007)
15. N. Theys, M.T. Ahn, T. Bouckenooghe, B. Reusens, C. Remacle, Maternal malnutrition programs pancreatic islet mitochondrial dysfunction in the adult offspring. J. Nutr. Biochem. 22, 985-994 (2010)
16. G.J. Howie, D.M. Sloboda, T. Kamal, M.H. Vickers, Maternal nutritional history predicts obesity in adult offspring independent of postnatal diet. J. Physiol. 587, 905-915 (2009)
17. N.G. Ashino, K.N. Saito, F.D. Souza, F.S. Nakutz, E.A. Roman, L.A. Velloso, A.S. Torsoni, M.A. Torsoni, Maternal high-fat feeding through pregnancy and lactation predisposes mouse offspring to molecular insulin resistance and fatty liver. J. Nutr. Biochem. 23, 341-348 (2011)
18. S. Rawana, K. Clark, S. Zhong, A. Buison, S. Chackunkal, K.L. Jen, Low dose fructose ingestion during gestation and lactation affects carbohydrate metabolism in rat dams and their offspring. J. Nutr. 123, 2158-2165 (1993)
19. K.L. Jen, C. Rochon, S.B. Zhong, L. Whitcomb, Fructose and sucrose feeding during pregnancy and lactation in rats changes maternal and pup fuel metabolism. J. Nutr. 121, 1999-2005 (1991)
20. M.A. Fergusson, K.G. Koski, Comparison of effects of dietary glucose versus fructose during pregnancy on fetal growth and development in rats. J. Nutr. 120, 1312-1319 (1990)
21. M.H. Vickers, Z.E. Clayton, C. Yap, D.M. Sloboda, Maternal fructose intake during pregnancy and lactation alters placental growth and leads to sex-specific changes in fetal and neonatal endocrine function. Endocrinology 152, 1378-1387 (2011)
22. D.R. Matthews, J.P. Hosker, A.S. Rudenski, B.A. Naylor, D.F. Treacher, R.C. Turner, Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28, 412-419 (1985)
23. J. Folch, M. Lees, G.H. Sloane Stanley, A simple method for the isolation and purification of total lipides from animal tissues. J. Biol. Chem. 226, 497-509 (1957)
24. J.M. Keller, P. Collet, A. Bianchi, C. Huin, P. Bouillaud-Kremarik, P. Becuwe, H. Schohn, L. Domenjoud, M. Dauca, Implications of peroxisome proliferator-activated receptors (PPARS) in development, cell life status and disease. Int. J. Dev. Biol. 44, 429-442 (2000)
25. E.A. Reece, C. Homko, A. Wiznitzer, Metabolic changes in diabetic and nondiabetic subjects during pregnancy. Obstet. Gynecol. Surv. 49, 64-71 (1994)
26. N.F. Butte, Carbohydrate and lipid metabolism in pregnancy: normal compared with gestational diabetes mellitus. Am. J. Clin. Nutr. 71, 1256S-1261S (2000)
27. N.V. Costrini, R.K. Kalkhoff, Relative effects of pregnancy, estradiol, and progesterone on plasma insulin and pancreatic islet insulin secretion. J. Clin. Invest. 50, 992-999 (1971)
28. C. Munoz, P. Lopez-Luna, E. Herrera, Glucose and insulin tolerance tests in the rat on different days of gestation. Biol. Neonate 68, 282-291 (1995)
29. J. Sleder, Y.D. Chen, M.D. Cully, G.M. Reaven, Hyperinsulinemia in fructose-induced hypertriglyceridemia in the rat. Metabolism 29, 303-305 (1980)
30. M.J. Dekker, Q. Su, C. Baker, A.C. Rutledge, K. Adeli, Fructose: a highly lipogenic nutrient implicated in insulin resistance, hepatic steatosis, and the metabolic syndrome. Am. J. Physiol. Endocrinol. Metab. 299, E685-E694 (2010)
31. J.F. Giani, M.A. Mayer, M.C. Munoz, E.A. Silberman, C. Hocht, C.A. Taira, M.M. Gironacci, D. Turyn, F.P. Dominici, Chronic infusion of angiotensin-(1-7) improves insulin resistance and hypertension induced by a high-fructose diet in rats. Am. J. Physiol. Endocrinol. Metab. 296, E262-E271 (2009)
32. M.S. Strable, J.M. Ntambi, Genetic control of de novo lipogenesis: role in diet-induced obesity. Crit. Rev. Biochem. Mol. Biol. 45, 199-214 (2010)
33. A.C. Rutledge, K. Adeli, Fructose and the metabolic syndrome: pathophysiology and molecular mechanisms. Nutr. Rev. 65, S13-S23 (2007)
34. Y. Sakar, C. Nazaret, P. Letteron, A. Ait Omar, M. Avenati, B. Viollet, R. Letteron, A. Bado, Positive regulatory control loop between gut leptin and intestinal GLUT2/GLUT5 transporters links to hepatic metabolic functions in rodents. PLoS ONE 4, e7935 (2009)
35. Y. Nagai, Y. Nishio, T. Nakamura, H. Maegawa, R. Kikkawa, A. Kashiwagi, Amelioration of high fructose-induced metabolic derangements by activation of PPARα. Am. J. Physiol. Endocrinol. Metab. 282, E1180-E1190 (2002)
36. M. Miyazaki, A. Dobrzyn, W.C. Man, K. Chu, H. Sampath, H.J. Kim, J.M. Ntambi, Stearoyl-CoA desaturase 1 gene expression is necessary for fructose-mediated induction of lipogenic gene expression by sterol regulatory element-binding protein-1c-dependent and -independent mechanisms. J. Biol. Chem. 279, 25164-25171 (2004)
37. T. Takemoto, Y. Nishio, O. Sekine, C. Ikeuchi, Y. Nagai, Y. Maeno, H. Maegawa, H. Kimura, A. Kashiwagi, RBMX is a novel hepatic transcriptional regulator of SREBP-1c gene response to high-fructose diet. FEBS Lett. 581, 218-222 (2007)
38. S. Shrestha, S.J. Ehlers, J.Y. Lee, M.L. Fernandez, S.I. Koo, Dietary green tea extract lowers plasma and hepatic triglycerides and decreases the expression of sterol regulatory element-binding protein-1c mRNA and its responsive genes in fructose-fed, ovariectomized rats. J. Nutr. 139, 640-645 (2009)
39. E. Herrera, Lipid metabolism in pregnancy and its consequences in the fetus and newborn. Endocrine 19, 43-55 (2002)
40. N. Roglans, E. Sanguino, C. Peris, M. Alegret, M. Vazquez, T. Adzet, C. Diaz, G. Hernandez, J.C. Laguna, R.M. Sanchez, Atorvastatin treatment induced peroxisome proliferator-activated receptor alpha expression and decreased plasma nonesterified fatty acids and liver triglyceride in fructose-fed rats. J. Pharmacol. Exp. Ther. 302, 232-239 (2002)
41. A. Ericsson, K. Saljo, E. Sjostrand, N. Jansson, P.D. Prasad, T.L. Powell, T. Jansson, Brief hyperglycaemia in the early pregnant rat increases fetal weight at term by stimulating placental growth and affecting placental nutrient transport. J. Physiol. 581, 1323-1332 (2007)