Identification of sirtuin 5 inhibitors by ultrafast microchip electrophoresis using nanoliter volume samples

Analytical and Bioanalytical Chemistry

Volumn 408, Issue 3, 2016, Pages 721-731

  Guetschow, Erik D ^a   Kumar, Surinder ^b   Lombard, David B ^b,c   Kennedy, Robert T ^a,b  

^a UNIVERSITY OF MICHIGAN   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

Author keywords

Droplets; Electrophoresis; Microfluidics; Screening; Sirtuin

Indexed keywords

AMINO ACIDS; ASSAYS; DROPS; DRUG PRODUCTS; ELECTROPHORESIS; LIGHT MODULATORS; MICROFLUIDICS; MICROPROCESSOR CHIPS; SCREENING; THROUGHPUT;

DOSE-RESPONSE ANALYSIS; ENGINEERED-SUBSTRATE; FLUOROGENIC SUBSTRATE; HIGH-THROUGHPUT SCREENING; MICROCHIP ELECTROPHORESIS; POST-TRANSLATIONAL MODIFICATIONS; SIRTUIN; SUCCINATE DEHYDROGENASE;

SUBSTRATES;

ENZYME INHIBITOR; SIRTUIN;

ANTAGONISTS AND INHIBITORS; CHEMISTRY; DEVICES; ENZYME SPECIFICITY; EVALUATION STUDY; KINETICS; MICROCHIP ELECTROPHORESIS; PROCEDURES;

ELECTROPHORESIS, MICROCHIP; ENZYME INHIBITORS; KINETICS; SIRTUINS; SUBSTRATE SPECIFICITY;

EID: 84955215727     PISSN: 16182642     EISSN: 16182650     Source Type: Journal    
DOI: 10.1007/s00216-015-9206-0     Document Type: Article

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