Studying SIRT6 regulation using H3K56 based substrate and small molecules

European Journal of Pharmaceutical Sciences

Volumn 63, Issue , 2014, Pages 71-76

  Kokkonen, Piia ^a   Rahnasto Rilla, Minna ^a   Mellini, Paolo ^b   Jarho, Elina ^a   Lahtela Kakkonen, Maija ^a   Kokkola, Tarja ^a  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

Fluorometric assay; Histone deacetylase; Nicotinamide; SIRT6; Sirtuins

Indexed keywords

HISTONE H3; LYSINE; NICOTINAMIDE; PROTEIN P53; QUERCETIN; RESVERATROL; SIRTINOL; SIRTUIN 1; SIRTUIN 6; SURAMIN; 6-CHLORO-2,3,4,9-TETRAHYDRO-1H-CARBAZOLE-1-CARBOXAMIDE; CARBAZOLE DERIVATIVE; HISTONE; PEPTIDE; RECOMBINANT PROTEIN; SIRT6 PROTEIN, HUMAN; SIRTUIN;

ARTICLE; CELL ADHESION; CONTROLLED STUDY; DEACETYLATION; DNA DAMAGE; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REGULATION; ENZYME SUBSTRATE; GENOMIC INSTABILITY; HISTONE ACETYLATION; HUMAN; IC 50; IN VITRO STUDY; IN VIVO STUDY; MICHAELIS MENTEN KINETICS; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; TELOMERE; ACETYLATION; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECTS; METABOLISM; STRUCTURE ACTIVITY RELATION;

ACETYLATION; CARBAZOLES; HISTONES; HUMANS; MOLECULAR STRUCTURE; NIACINAMIDE; PEPTIDES; QUERCETIN; RECOMBINANT PROTEINS; SIRTUINS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84905164120     PISSN: 09280987     EISSN: 18790720     Source Type: Journal    
DOI: 10.1016/j.ejps.2014.06.015     Document Type: Article

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