-
1
-
-
84904872156
-
The growing landscape of lysine acetylation links metabolism and cell signalling
-
Choudhary, C.; Weinert, B. T.; Nishida, Y.; Verdin, E.; Mann, M. The growing landscape of lysine acetylation links metabolism and cell signalling Nat. Rev. Mol. Cell Biol. 2014, 15, 536-550 10.1038/nrm3841
-
(2014)
Nat. Rev. Mol. Cell Biol.
, vol.15
, pp. 536-550
-
-
Choudhary, C.1
Weinert, B.T.2
Nishida, Y.3
Verdin, E.4
Mann, M.5
-
2
-
-
77149148756
-
Regulation of cellular metabolism by protein lysine acetylation
-
Zhao, S.; Xu, W.; Jiang, W.; Yu, W.; Lin, Y.; Zhang, T.; Yao, J.; Zhou, L.; Zeng, Y.; Li, H.; Li, Y.; Shi, J.; An, W.; Hancock, S. M.; He, F.; Qin, L.; Chin, J.; Yang, P.; Chen, X.; Lei, Q.; Xiong, Y.; Guan, K. L. Regulation of cellular metabolism by protein lysine acetylation Science 2010, 327, 1000-1004 10.1126/science.1179689
-
(2010)
Science
, vol.327
, pp. 1000-1004
-
-
Zhao, S.1
Xu, W.2
Jiang, W.3
Yu, W.4
Lin, Y.5
Zhang, T.6
Yao, J.7
Zhou, L.8
Zeng, Y.9
Li, H.10
Li, Y.11
Shi, J.12
An, W.13
Hancock, S.M.14
He, F.15
Qin, L.16
Chin, J.17
Yang, P.18
Chen, X.19
Lei, Q.20
Xiong, Y.21
Guan, K.L.22
more..
-
3
-
-
34248640428
-
Lysine propionylation and butyrylation are novel post-translational modifications in histones
-
Chen, Y.; Sprung, R.; Tang, Y.; Ball, H.; Sangras, B.; Kim, S. C.; Falck, J. R.; Peng, J.; Gu, W.; Zhao, Y. Lysine propionylation and butyrylation are novel post-translational modifications in histones Mol. Cell. Proteomics 2007, 6, 812-819 10.1074/mcp.M700021-MCP200
-
(2007)
Mol. Cell. Proteomics
, vol.6
, pp. 812-819
-
-
Chen, Y.1
Sprung, R.2
Tang, Y.3
Ball, H.4
Sangras, B.5
Kim, S.C.6
Falck, J.R.7
Peng, J.8
Gu, W.9
Zhao, Y.10
-
4
-
-
35648935529
-
N-lysine propionylation controls the activity of propionyl-CoA synthetase
-
Garrity, J.; Gardner, J. G.; Hawse, W.; Wolberger, C.; Escalante-Semerena, J. C. N-lysine propionylation controls the activity of propionyl-CoA synthetase J. Biol. Chem. 2007, 282, 30239-30245 10.1074/jbc.M704409200
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 30239-30245
-
-
Garrity, J.1
Gardner, J.G.2
Hawse, W.3
Wolberger, C.4
Escalante-Semerena, J.C.5
-
5
-
-
78650516004
-
Identification of lysine succinylation as a new post-translational modification
-
Zhang, Z.; Tan, M.; Xie, Z.; Dai, L.; Chen, Y.; Zhao, Y. Identification of lysine succinylation as a new post-translational modification Nat. Chem. Biol. 2011, 7, 58-63 10.1038/nchembio.495
-
(2011)
Nat. Chem. Biol.
, vol.7
, pp. 58-63
-
-
Zhang, Z.1
Tan, M.2
Xie, Z.3
Dai, L.4
Chen, Y.5
Zhao, Y.6
-
6
-
-
84861163510
-
Lysine succinylation and lysine malonylation in histones
-
Xie, Z.; Dai, J.; Dai, L.; Tan, M.; Cheng, Z.; Wu, Y.; Boeke, J. D.; Zhao, Y. Lysine succinylation and lysine malonylation in histones Mol. Cell. Proteomics 2012, 11, 100-107 10.1074/mcp.M111.015875
-
(2012)
Mol. Cell. Proteomics
, vol.11
, pp. 100-107
-
-
Xie, Z.1
Dai, J.2
Dai, L.3
Tan, M.4
Cheng, Z.5
Wu, Y.6
Boeke, J.D.7
Zhao, Y.8
-
7
-
-
83055173304
-
The first identification of lysine malonylation substrates and its regulatory enzyme
-
Peng, C.; Lu, Z.; Xie, Z.; Cheng, Z.; Chen, Y.; Tan, M.; Luo, H.; Zhang, Y.; He, W.; Yang, K.; Zwaans, B. M.; Tishkoff, D.; Ho, L.; Lombard, D.; He, T. C.; Dai, J.; Verdin, E.; Ye, Y.; Zhao, Y. The first identification of lysine malonylation substrates and its regulatory enzyme Mol. Cell. Proteomics 2011, 10, M111.012658 10.1074/mcp.M111.012658
-
(2011)
Mol. Cell. Proteomics
, vol.10
, pp. M111012658
-
-
Peng, C.1
Lu, Z.2
Xie, Z.3
Cheng, Z.4
Chen, Y.5
Tan, M.6
Luo, H.7
Zhang, Y.8
He, W.9
Yang, K.10
Zwaans, B.M.11
Tishkoff, D.12
Ho, L.13
Lombard, D.14
He, T.C.15
Dai, J.16
Verdin, E.17
Ye, Y.18
Zhao, Y.19
-
8
-
-
84897565291
-
Lysine glutarylation is a protein posttranslational modification regulated by SIRT5
-
Tan, M.; Peng, C.; Anderson, K. A.; Chhoy, P.; Xie, Z.; Dai, L.; Park, J.; Chen, Y.; Huang, H.; Zhang, Y.; Ro, J.; Wagner, G. R.; Green, M. F.; Madsen, A. S.; Schmiesing, J.; Peterson, B. S.; Xu, G.; Ilkayeva, O. R.; Muehlbauer, M. J.; Braulke, T.; Muhlhausen, C.; Backos, D. S.; Olsen, C. A.; McGuire, P. J.; Pletcher, S. D.; Lombard, D. B.; Hirschey, M. D.; Zhao, Y. Lysine glutarylation is a protein posttranslational modification regulated by SIRT5 Cell Metab. 2014, 19, 605-617 10.1016/j.cmet.2014.03.014
-
(2014)
Cell Metab.
, vol.19
, pp. 605-617
-
-
Tan, M.1
Peng, C.2
Anderson, K.A.3
Chhoy, P.4
Xie, Z.5
Dai, L.6
Park, J.7
Chen, Y.8
Huang, H.9
Zhang, Y.10
Ro, J.11
Wagner, G.R.12
Green, M.F.13
Madsen, A.S.14
Schmiesing, J.15
Peterson, B.S.16
Xu, G.17
Ilkayeva, O.R.18
Muehlbauer, M.J.19
Braulke, T.20
Muhlhausen, C.21
Backos, D.S.22
Olsen, C.A.23
McGuire, P.J.24
Pletcher, S.D.25
Lombard, D.B.26
Hirschey, M.D.27
Zhao, Y.28
more..
-
9
-
-
80052942443
-
Identification of 67 histone marks and histone lysine crotonylation as a new type of histone modification
-
Tan, M.; Luo, H.; Lee, S.; Jin, F.; Yang, J. S.; Montellier, E.; Buchou, T.; Cheng, Z.; Rousseaux, S.; Rajagopal, N.; Lu, Z.; Ye, Z.; Zhu, Q.; Wysocka, J.; Ye, Y.; Khochbin, S.; Ren, B.; Zhao, Y. Identification of 67 histone marks and histone lysine crotonylation as a new type of histone modification Cell 2011, 146, 1016-1028 10.1016/j.cell.2011.08.008
-
(2011)
Cell
, vol.146
, pp. 1016-1028
-
-
Tan, M.1
Luo, H.2
Lee, S.3
Jin, F.4
Yang, J.S.5
Montellier, E.6
Buchou, T.7
Cheng, Z.8
Rousseaux, S.9
Rajagopal, N.10
Lu, Z.11
Ye, Z.12
Zhu, Q.13
Wysocka, J.14
Ye, Y.15
Khochbin, S.16
Ren, B.17
Zhao, Y.18
-
10
-
-
0027219723
-
The 31-kDa precursor of interleukin 1 alpha is myristoylated on specific lysines within the 16-kDa N-terminal propiece
-
Stevenson, F. T.; Bursten, S. L.; Fanton, C.; Locksley, R. M.; Lovett, D. H. The 31-kDa precursor of interleukin 1 alpha is myristoylated on specific lysines within the 16-kDa N-terminal propiece Proc. Natl. Acad. Sci. U. S. A. 1993, 90, 7245-7249 10.1073/pnas.90.15.7245
-
(1993)
Proc. Natl. Acad. Sci. U. S. A.
, vol.90
, pp. 7245-7249
-
-
Stevenson, F.T.1
Bursten, S.L.2
Fanton, C.3
Locksley, R.M.4
Lovett, D.H.5
-
11
-
-
84885155285
-
Widespread and enzyme-independent Nepsilon-acetylation and Nepsilon-succinylation of proteins in the chemical conditions of the mitochondrial matrix
-
Wagner, G. R.; Payne, R. M. Widespread and enzyme-independent Nepsilon-acetylation and Nepsilon-succinylation of proteins in the chemical conditions of the mitochondrial matrix J. Biol. Chem. 2013, 288, 29036-29045 10.1074/jbc.M113.486753
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 29036-29045
-
-
Wagner, G.R.1
Payne, R.M.2
-
12
-
-
84880426255
-
Acetyl-phosphate is a critical determinant of lysine acetylation in E. Coli
-
Weinert, B. T.; Iesmantavicius, V.; Wagner, S. A.; Scholz, C.; Gummesson, B.; Beli, P.; Nystrom, T.; Choudhary, C. Acetyl-phosphate is a critical determinant of lysine acetylation in E. coli Mol. Cell 2013, 51, 265-272 10.1016/j.molcel.2013.06.003
-
(2013)
Mol. Cell
, vol.51
, pp. 265-272
-
-
Weinert, B.T.1
Iesmantavicius, V.2
Wagner, S.A.3
Scholz, C.4
Gummesson, B.5
Beli, P.6
Nystrom, T.7
Choudhary, C.8
-
13
-
-
84899668522
-
Structural, kinetic and proteomic characterization of acetyl phosphate-dependent bacterial protein acetylation
-
Kuhn, M. L.; Zemaitaitis, B.; Hu, L. I.; Sahu, A.; Sorensen, D.; Minasov, G.; Lima, B. P.; Scholle, M.; Mrksich, M.; Anderson, W. F.; Gibson, B. W.; Schilling, B.; Wolfe, A. J. Structural, kinetic and proteomic characterization of acetyl phosphate-dependent bacterial protein acetylation PLoS One 2014, 9, e94816 10.1371/journal.pone.0094816
-
(2014)
PLoS One
, vol.9
, pp. e94816
-
-
Kuhn, M.L.1
Zemaitaitis, B.2
Hu, L.I.3
Sahu, A.4
Sorensen, D.5
Minasov, G.6
Lima, B.P.7
Scholle, M.8
Mrksich, M.9
Anderson, W.F.10
Gibson, B.W.11
Schilling, B.12
Wolfe, A.J.13
-
14
-
-
84886686038
-
Activation of the protein deacetylase SIRT6 by long-chain fatty acids and widespread deacylation by mammalian sirtuins
-
Feldman, J. L.; Baeza, J.; Denu, J. M. Activation of the protein deacetylase SIRT6 by long-chain fatty acids and widespread deacylation by mammalian sirtuins J. Biol. Chem. 2013, 288, 31350-31356 10.1074/jbc.C113.511261
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 31350-31356
-
-
Feldman, J.L.1
Baeza, J.2
Denu, J.M.3
-
15
-
-
81055122671
-
Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase
-
Du, J.; Zhou, Y.; Su, X.; Yu, J. J.; Khan, S.; Jiang, H.; Kim, J.; Woo, J.; Kim, J. H.; Choi, B. H.; He, B.; Chen, W.; Zhang, S.; Cerione, R. A.; Auwerx, J.; Hao, Q.; Lin, H. Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase Science 2011, 334, 806-809 10.1126/science.1207861
-
(2011)
Science
, vol.334
, pp. 806-809
-
-
Du, J.1
Zhou, Y.2
Su, X.3
Yu, J.J.4
Khan, S.5
Jiang, H.6
Kim, J.7
Woo, J.8
Kim, J.H.9
Choi, B.H.10
He, B.11
Chen, W.12
Zhang, S.13
Cerione, R.A.14
Auwerx, J.15
Hao, Q.16
Lin, H.17
-
16
-
-
84880791239
-
SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways
-
Park, J.; Chen, Y.; Tishkoff, D. X.; Peng, C.; Tan, M.; Dai, L.; Xie, Z.; Zhang, Y.; Zwaans, B. M.; Skinner, M. E.; Lombard, D. B.; Zhao, Y. SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways Mol. Cell 2013, 50, 919-930 10.1016/j.molcel.2013.06.001
-
(2013)
Mol. Cell
, vol.50
, pp. 919-930
-
-
Park, J.1
Chen, Y.2
Tishkoff, D.X.3
Peng, C.4
Tan, M.5
Dai, L.6
Xie, Z.7
Zhang, Y.8
Zwaans, B.M.9
Skinner, M.E.10
Lombard, D.B.11
Zhao, Y.12
-
17
-
-
84919933749
-
Sirtuin 4 is a lipoamidase regulating pyruvate dehydrogenase complex activity
-
Mathias, R. A.; Greco, T. M.; Oberstein, A.; Budayeva, H. G.; Chakrabarti, R.; Rowland, E. A.; Kang, Y.; Shenk, T.; Cristea, I. M. Sirtuin 4 is a lipoamidase regulating pyruvate dehydrogenase complex activity Cell 2014, 159, 1615-1625 10.1016/j.cell.2014.11.046
-
(2014)
Cell
, vol.159
, pp. 1615-1625
-
-
Mathias, R.A.1
Greco, T.M.2
Oberstein, A.3
Budayeva, H.G.4
Chakrabarti, R.5
Rowland, E.A.6
Kang, Y.7
Shenk, T.8
Cristea, I.M.9
-
18
-
-
84996553972
-
Identification of erasers for lysine crotonylated histone marks using a chemical proteomics approach
-
Bao, X.; Wang, Y.; Li, X.; Li, X. M.; Liu, Z.; Yang, T.; Wong, C. F.; Zhang, J.; Hao, Q.; Li, X. D. Identification of erasers for lysine crotonylated histone marks using a chemical proteomics approach eLife 2014, 3, e02999 10.7554/eLife.02999
-
(2014)
ELife
, vol.3
, pp. e02999
-
-
Bao, X.1
Wang, Y.2
Li, X.3
Li, X.M.4
Liu, Z.5
Yang, T.6
Wong, C.F.7
Zhang, J.8
Hao, Q.9
Li, X.D.10
-
19
-
-
33751113602
-
Mammalian sirtuins - Emerging roles in physiology, aging, and calorie restriction
-
Haigis, M. C.; Guarente, L. P. Mammalian sirtuins - emerging roles in physiology, aging, and calorie restriction Genes Dev. 2006, 20, 2913-2921 10.1101/gad.1467506
-
(2006)
Genes Dev.
, vol.20
, pp. 2913-2921
-
-
Haigis, M.C.1
Guarente, L.P.2
-
20
-
-
78649993987
-
Electrophoretically mediated microanalysis assay for sirtuin enzymes
-
Fan, Y.; Scriba, G. K. Electrophoretically mediated microanalysis assay for sirtuin enzymes Electrophoresis 2010, 31, 3874-3880 10.1002/elps.201000336
-
(2010)
Electrophoresis
, vol.31
, pp. 3874-3880
-
-
Fan, Y.1
Scriba, G.K.2
-
21
-
-
0034687694
-
Silent information regulator 2 family of NAD- dependent histone/protein deacetylases generates a unique product, 1-O-acetyl-ADP-ribose
-
Tanner, K. G.; Landry, J.; Sternglanz, R.; Denu, J. M. Silent information regulator 2 family of NAD- dependent histone/protein deacetylases generates a unique product, 1-O-acetyl-ADP-ribose Proc. Natl. Acad. Sci. U. S. A. 2000, 97, 14178-14182 10.1073/pnas.250422697
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 14178-14182
-
-
Tanner, K.G.1
Landry, J.2
Sternglanz, R.3
Denu, J.M.4
-
22
-
-
84928905812
-
Chemical probing of the human sirtuin 5 active site reveals its substrate acyl specificity and Peptide-based inhibitors
-
Roessler, C.; Nowak, T.; Pannek, M.; Gertz, M.; Nguyen, G. T.; Scharfe, M.; Born, I.; Sippl, W.; Steegborn, C.; Schutkowski, M. Chemical probing of the human sirtuin 5 active site reveals its substrate acyl specificity and Peptide-based inhibitors Angew. Chem., Int. Ed. 2014, 53, 10728-10732 10.1002/anie.201402679
-
(2014)
Angew. Chem., Int. Ed.
, vol.53
, pp. 10728-10732
-
-
Roessler, C.1
Nowak, T.2
Pannek, M.3
Gertz, M.4
Nguyen, G.T.5
Scharfe, M.6
Born, I.7
Sippl, W.8
Steegborn, C.9
Schutkowski, M.10
-
23
-
-
4143100391
-
Fluorescence assay of SIRT protein deacetylases using an acetylated peptide substrate and a secondary trypsin reaction
-
Marcotte, P. A.; Richardson, P. L.; Guo, J.; Barrett, L. W.; Xu, N.; Gunasekera, A.; Glaser, K. B. Fluorescence assay of SIRT protein deacetylases using an acetylated peptide substrate and a secondary trypsin reaction Anal. Biochem. 2004, 332, 90-99 10.1016/j.ab.2004.05.039
-
(2004)
Anal. Biochem.
, vol.332
, pp. 90-99
-
-
Marcotte, P.A.1
Richardson, P.L.2
Guo, J.3
Barrett, L.W.4
Xu, N.5
Gunasekera, A.6
Glaser, K.B.7
-
24
-
-
84874721105
-
Evidence for a common mechanism of SIRT1 regulation by allosteric activators
-
Hubbard, B. P.; Gomes, A. P.; Dai, H.; Li, J.; Case, A. W.; Considine, T.; Riera, T. V.; Lee, J. E.; SY, E.; Lamming, D. W.; Pentelute, B. L.; Schuman, E. R.; Stevens, L. A.; Ling, A. J.; Armour, S. M.; Michan, S.; Zhao, H.; Jiang, Y.; Sweitzer, S. M.; Blum, C. A.; Disch, J. S.; Ng, P. Y.; Howitz, K. T.; Rolo, A. P.; Hamuro, Y.; Moss, J.; Perni, R. B.; Ellis, J. L.; Vlasuk, G. P.; Sinclair, D. A. Evidence for a common mechanism of SIRT1 regulation by allosteric activators Science 2013, 339, 1216-1219 10.1126/science.1231097
-
(2013)
Science
, vol.339
, pp. 1216-1219
-
-
Hubbard, B.P.1
Gomes, A.P.2
Dai, H.3
Li, J.4
Case, A.W.5
Considine, T.6
Riera, T.V.7
Lee, J.E.8
Sy, E.9
Lamming, D.W.10
Pentelute, B.L.11
Schuman, E.R.12
Stevens, L.A.13
Ling, A.J.14
Armour, S.M.15
Michan, S.16
Zhao, H.17
Jiang, Y.18
Sweitzer, S.M.19
Blum, C.A.20
Disch, J.S.21
Ng, P.Y.22
Howitz, K.T.23
Rolo, A.P.24
Hamuro, Y.25
Moss, J.26
Perni, R.B.27
Ellis, J.L.28
Vlasuk, G.P.29
Sinclair, D.A.30
more..
-
25
-
-
69249206539
-
A continuous microplate assay for sirtuins and nicotinamide-producing enzymes
-
Smith, B. C.; Hallows, W. C.; Denu, J. M. A continuous microplate assay for sirtuins and nicotinamide-producing enzymes Anal. Biochem. 2009, 394, 101-109 10.1016/j.ab.2009.07.019
-
(2009)
Anal. Biochem.
, vol.394
, pp. 101-109
-
-
Smith, B.C.1
Hallows, W.C.2
Denu, J.M.3
-
26
-
-
84900562559
-
An enzyme-coupled assay measuring acetate production for profiling histone deacetylase specificity
-
Wolfson, N. A.; Pitcairn, C. A.; Sullivan, E. D.; Joseph, C. G.; Fierke, C. A. An enzyme-coupled assay measuring acetate production for profiling histone deacetylase specificity Anal. Biochem. 2014, 456, 61-69 10.1016/j.ab.2014.03.012
-
(2014)
Anal. Biochem.
, vol.456
, pp. 61-69
-
-
Wolfson, N.A.1
Pitcairn, C.A.2
Sullivan, E.D.3
Joseph, C.G.4
Fierke, C.A.5
-
27
-
-
84893149368
-
New assays and approaches for discovery and design of Sirtuin modulators
-
Schutkowski, M.; Fischer, F.; Roessler, C.; Steegborn, C. New assays and approaches for discovery and design of Sirtuin modulators Expert Opin. Drug Discovery 2014, 9, 183-199 10.1517/17460441.2014.875526
-
(2014)
Expert Opin. Drug Discovery
, vol.9
, pp. 183-199
-
-
Schutkowski, M.1
Fischer, F.2
Roessler, C.3
Steegborn, C.4
-
28
-
-
0037253808
-
A fluorogenic histone deacetylase assay well suited for high-throughput activity screening
-
Wegener, D.; Wirsching, F.; Riester, D.; Schwienhorst, A. A fluorogenic histone deacetylase assay well suited for high-throughput activity screening Chem. Biol. 2003, 10, 61-68 10.1016/S1074-5521(02)00305-8
-
(2003)
Chem. Biol.
, vol.10
, pp. 61-68
-
-
Wegener, D.1
Wirsching, F.2
Riester, D.3
Schwienhorst, A.4
-
29
-
-
84865790010
-
Development of a fluorogenic probe with a transesterification switch for detection of histone deacetylase activity
-
Baba, R.; Hori, Y.; Mizukami, S.; Kikuchi, K. Development of a fluorogenic probe with a transesterification switch for detection of histone deacetylase activity J. Am. Chem. Soc. 2012, 134, 14310-14313 10.1021/ja306045j
-
(2012)
J. Am. Chem. Soc.
, vol.134
, pp. 14310-14313
-
-
Baba, R.1
Hori, Y.2
Mizukami, S.3
Kikuchi, K.4
-
30
-
-
84905706941
-
Development of a fluorogenic probe based on a DNA staining dye for continuous monitoring of the histone deacetylase reaction
-
Minoshima, M.; Matsumoto, T.; Kikuchi, K. Development of a fluorogenic probe based on a DNA staining dye for continuous monitoring of the histone deacetylase reaction Anal. Chem. 2014, 86, 7925-7930 10.1021/ac501881s
-
(2014)
Anal. Chem.
, vol.86
, pp. 7925-7930
-
-
Minoshima, M.1
Matsumoto, T.2
Kikuchi, K.3
-
31
-
-
84868381323
-
A fluorescent probe for detection of histone deacetylase activity based on aggregation-induced emission
-
Dhara, K.; Hori, Y.; Baba, R.; Kikuchi, K. A fluorescent probe for detection of histone deacetylase activity based on aggregation-induced emission Chem. Commun. (Cambridge, U. K.) 2012, 48, 11534-11536 10.1039/c2cc36591j
-
(2012)
Chem. Commun. (Cambridge, U. K.)
, vol.48
, pp. 11534-11536
-
-
Dhara, K.1
Hori, Y.2
Baba, R.3
Kikuchi, K.4
-
32
-
-
84869816787
-
A molecular mechanism for direct sirtuin activation by resveratrol
-
Gertz, M.; Nguyen, G. T.; Fischer, F.; Suenkel, B.; Schlicker, C.; Franzel, B.; Tomaschewski, J.; Aladini, F.; Becker, C.; Wolters, D.; Steegborn, C. A molecular mechanism for direct sirtuin activation by resveratrol PLoS One 2012, 7, e49761 10.1371/journal.pone.0049761
-
(2012)
PLoS One
, vol.7
, pp. e49761
-
-
Gertz, M.1
Nguyen, G.T.2
Fischer, F.3
Suenkel, B.4
Schlicker, C.5
Franzel, B.6
Tomaschewski, J.7
Aladini, F.8
Becker, C.9
Wolters, D.10
Steegborn, C.11
-
33
-
-
84862271824
-
Substrates for efficient fluorometric screening employing the NAD-dependent sirtuin 5 lysine deacylase (KDAC) enzyme
-
Madsen, A. S.; Olsen, C. A. Substrates for efficient fluorometric screening employing the NAD-dependent sirtuin 5 lysine deacylase (KDAC) enzyme J. Med. Chem. 2012, 55, 5582-5590 10.1021/jm300526r
-
(2012)
J. Med. Chem.
, vol.55
, pp. 5582-5590
-
-
Madsen, A.S.1
Olsen, C.A.2
-
34
-
-
84871253229
-
Inhibitors of the NAD(+)-Dependent Protein Desuccinylase and Demalonylase Sirt5
-
Maurer, B.; Rumpf, T.; Scharfe, M.; Stolfa, D. A.; Schmitt, M. L.; He, W.; Verdin, E.; Sippl, W.; Jung, M. Inhibitors of the NAD(+)-Dependent Protein Desuccinylase and Demalonylase Sirt5 ACS Med. Chem. Lett. 2012, 3, 1050-1053 10.1021/ml3002709
-
(2012)
ACS Med. Chem. Lett.
, vol.3
, pp. 1050-1053
-
-
Maurer, B.1
Rumpf, T.2
Scharfe, M.3
Stolfa, D.A.4
Schmitt, M.L.5
He, W.6
Verdin, E.7
Sippl, W.8
Jung, M.9
-
35
-
-
84884163378
-
An acetylome peptide microarray reveals specificities and deacetylation substrates for all human sirtuin isoforms
-
Rauh, D.; Fischer, F.; Gertz, M.; Lakshminarasimhan, M.; Bergbrede, T.; Aladini, F.; Kambach, C.; Becker, C. F.; Zerweck, J.; Schutkowski, M.; Steegborn, C. An acetylome peptide microarray reveals specificities and deacetylation substrates for all human sirtuin isoforms Nat. Commun. 2013, 4, 2327 10.1038/ncomms3327
-
(2013)
Nat. Commun.
, vol.4
, pp. 2327
-
-
Rauh, D.1
Fischer, F.2
Gertz, M.3
Lakshminarasimhan, M.4
Bergbrede, T.5
Aladini, F.6
Kambach, C.7
Becker, C.F.8
Zerweck, J.9
Schutkowski, M.10
Steegborn, C.11
-
36
-
-
0025770925
-
Anthranilamide and nitrotyrosine as a donor-acceptor pair in internally quenched fluorescent substrates for endopeptidases: Multicolumn peptide synthesis of enzyme substrates for subtilisin Carlsberg and pepsin
-
Meldal, M.; Breddam, K. Anthranilamide and nitrotyrosine as a donor-acceptor pair in internally quenched fluorescent substrates for endopeptidases: multicolumn peptide synthesis of enzyme substrates for subtilisin Carlsberg and pepsin Anal. Biochem. 1991, 195, 141-147 10.1016/0003-2697(91)90309-H
-
(1991)
Anal. Biochem.
, vol.195
, pp. 141-147
-
-
Meldal, M.1
Breddam, K.2
-
37
-
-
38349008883
-
A high-complexity, multiplexed solution-phase assay for profiling protease activity on microarrays
-
Lebl, M.; Kozlov, I. A.; Melnyk, P. C.; Hachmann, J. P.; Srinivasan, A.; Shults, M.; Zhao, C.; Musmacker, J.; Nelson, N.; Barker, D. L. A high-complexity, multiplexed solution-phase assay for profiling protease activity on microarrays Comb. Chem. High Throughput Screening 2008, 11, 24-35 10.2174/138620708783398304
-
(2008)
Comb. Chem. High Throughput Screening
, vol.11
, pp. 24-35
-
-
Lebl, M.1
Kozlov, I.A.2
Melnyk, P.C.3
Hachmann, J.P.4
Srinivasan, A.5
Shults, M.6
Zhao, C.7
Musmacker, J.8
Nelson, N.9
Barker, D.L.10
-
38
-
-
84929600711
-
Kinetic and Structural Basis for Acyl-Group Selectivity and NAD Dependence in Sirtuin-Catalyzed Deacylation
-
Feldman, J. L.; Dittenhafer-Reed, K. E.; Kudo, N.; Thelen, J. N.; Ito, A.; Yoshida, M.; Denu, J. M. Kinetic and Structural Basis for Acyl-Group Selectivity and NAD Dependence in Sirtuin-Catalyzed Deacylation Biochemistry 2015, 54, 3037 10.1021/acs.biochem.5b00150
-
(2015)
Biochemistry
, vol.54
, pp. 3037
-
-
Feldman, J.L.1
Dittenhafer-Reed, K.E.2
Kudo, N.3
Thelen, J.N.4
Ito, A.5
Yoshida, M.6
Denu, J.M.7
-
39
-
-
84927590509
-
A FRET-based assay for screening SIRT6 modulators
-
Li, Y.; You, L.; Huang, W.; Liu, J.; Zhu, H.; He, B. A FRET-based assay for screening SIRT6 modulators Eur. J. Med. Chem. 2015, 96, 245-249 10.1016/j.ejmech.2015.04.008
-
(2015)
Eur. J. Med. Chem.
, vol.96
, pp. 245-249
-
-
Li, Y.1
You, L.2
Huang, W.3
Liu, J.4
Zhu, H.5
He, B.6
-
40
-
-
84866552404
-
Sirt5 deacylation activities show differential sensitivities to nicotinamide inhibition
-
Fischer, F.; Gertz, M.; Suenkel, B.; Lakshminarasimhan, M.; Schutkowski, M.; Steegborn, C. Sirt5 deacylation activities show differential sensitivities to nicotinamide inhibition PLoS One 2012, 7, e45098 10.1371/journal.pone.0045098
-
(2012)
PLoS One
, vol.7
, pp. e45098
-
-
Fischer, F.1
Gertz, M.2
Suenkel, B.3
Lakshminarasimhan, M.4
Schutkowski, M.5
Steegborn, C.6
-
41
-
-
33746484522
-
Nepsilon-thioacetyl-lysine: A multi-facet functional probe for enzymatic protein lysine Nepsilon-deacetylation
-
Fatkins, D. G.; Monnot, A. D.; Zheng, W. Nepsilon-thioacetyl-lysine: a multi-facet functional probe for enzymatic protein lysine Nepsilon-deacetylation Bioorg. Med. Chem. Lett. 2006, 16, 3651-3656 10.1016/j.bmcl.2006.04.075
-
(2006)
Bioorg. Med. Chem. Lett.
, vol.16
, pp. 3651-3656
-
-
Fatkins, D.G.1
Monnot, A.D.2
Zheng, W.3
-
42
-
-
37349110743
-
Mechanism-based inhibition of Sir2 deacetylases by thioacetyl-lysine peptide
-
Smith, B. C.; Denu, J. M. Mechanism-based inhibition of Sir2 deacetylases by thioacetyl-lysine peptide Biochemistry 2007, 46, 14478-14486 10.1021/bi7013294
-
(2007)
Biochemistry
, vol.46
, pp. 14478-14486
-
-
Smith, B.C.1
Denu, J.M.2
-
43
-
-
84863010942
-
Thiosuccinyl peptides as Sirt5-specific inhibitors
-
He, B.; Du, J.; Lin, H. Thiosuccinyl peptides as Sirt5-specific inhibitors J. Am. Chem. Soc. 2012, 134, 1922-1925 10.1021/ja2090417
-
(2012)
J. Am. Chem. Soc.
, vol.134
, pp. 1922-1925
-
-
He, B.1
Du, J.2
Lin, H.3
-
44
-
-
84865225339
-
The bicyclic intermediate structure provides insights into the desuccinylation mechanism of human sirtuin 5 (SIRT5)
-
Zhou, Y.; Zhang, H.; He, B.; Du, J.; Lin, H.; Cerione, R. A.; Hao, Q. The bicyclic intermediate structure provides insights into the desuccinylation mechanism of human sirtuin 5 (SIRT5) J. Biol. Chem. 2012, 287, 28307-28314 10.1074/jbc.M112.384511
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 28307-28314
-
-
Zhou, Y.1
Zhang, H.2
He, B.3
Du, J.4
Lin, H.5
Cerione, R.A.6
Hao, Q.7
-
45
-
-
84869192260
-
Leucine supplementation increases SIRT1 expression and prevents mitochondrial dysfunction and metabolic disorders in high-fat diet-induced obese mice
-
Li, H.; Xu, M.; Lee, J.; He, C.; Xie, Z. Leucine supplementation increases SIRT1 expression and prevents mitochondrial dysfunction and metabolic disorders in high-fat diet-induced obese mice Am. J. Physiol Endocrinol Metab 2012, 303, E1234-1244 10.1152/ajpendo.00198.2012
-
(2012)
Am. J. Physiol Endocrinol Metab
, vol.303
, pp. E1234-1244
-
-
Li, H.1
Xu, M.2
Lee, J.3
He, C.4
Xie, Z.5
-
46
-
-
64549094152
-
N(epsilon)-thioacetyl-lysine-containing tri-, tetra-, and pentapeptides as SIRT1 and SIRT2 inhibitors
-
Kiviranta, P. H.; Suuronen, T.; Wallen, E. A.; Leppanen, J.; Tervonen, J.; Kyrylenko, S.; Salminen, A.; Poso, A.; Jarho, E. M. N(epsilon)-thioacetyl-lysine-containing tri-, tetra-, and pentapeptides as SIRT1 and SIRT2 inhibitors J. Med. Chem. 2009, 52, 2153-2156 10.1021/jm801401k
-
(2009)
J. Med. Chem.
, vol.52
, pp. 2153-2156
-
-
Kiviranta, P.H.1
Suuronen, T.2
Wallen, E.A.3
Leppanen, J.4
Tervonen, J.5
Kyrylenko, S.6
Salminen, A.7
Poso, A.8
Jarho, E.M.9
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