메뉴 건너뛰기




Volumn 16, Issue 12, 2015, Pages 1609-1619

Chromatin remodeling and bivalent histone modifications in embryonic stem cells

Author keywords

chromatin; chromatin remodeling; embryonic stem cells; epigenetics; histone modifications

Indexed keywords

BRAHMA ASSOCIATED FACTOR COMPLEX ASSOCIATED WITH EMBRYONIC STEM CELL; HISTONE H3; INOSITOL REQUIRING 80; METHYLTRANSFERASE; NUCLEOSOME REMODELING DEACETYLASE; OCTAMER TRANSCRIPTION FACTOR 4; POLYCOMB GROUP PROTEIN; POLYCOMB REPRESSIVE COMPLEX 2; PROTEIN; UNCLASSIFIED DRUG; HISTONE; LYSINE;

EID: 84954371225     PISSN: 1469221X     EISSN: 14693178     Source Type: Journal    
DOI: 10.15252/embr.201541011     Document Type: Review
Times cited : (178)

References (106)
  • 1
    • 33847076849 scopus 로고    scopus 로고
    • Chromatin modifications and their function
    • Kouzarides T, (2007) Chromatin modifications and their function. Cell 128: 693-705
    • (2007) Cell , vol.128 , pp. 693-705
    • Kouzarides, T.1
  • 2
    • 79952534189 scopus 로고    scopus 로고
    • Regulation of chromatin by histone modifications
    • Bannister AJ, Kouzarides T, (2011) Regulation of chromatin by histone modifications. Cell Res 21: 381-395
    • (2011) Cell Res , vol.21 , pp. 381-395
    • Bannister, A.J.1    Kouzarides, T.2
  • 3
    • 84908151229 scopus 로고    scopus 로고
    • Histone core modifications regulating nucleosome structure and dynamics
    • Tessarz P, Kouzarides T, (2014) Histone core modifications regulating nucleosome structure and dynamics. Nat Rev Mol Cell Biol 15: 703-708
    • (2014) Nat Rev Mol Cell Biol , vol.15 , pp. 703-708
    • Tessarz, P.1    Kouzarides, T.2
  • 7
    • 84879260661 scopus 로고    scopus 로고
    • A double take on bivalent promoters
    • Voigt P, Tee WW, Reinberg D, (2013) A double take on bivalent promoters. Genes Dev 27: 1318-1338
    • (2013) Genes Dev , vol.27 , pp. 1318-1338
    • Voigt, P.1    Tee, W.W.2    Reinberg, D.3
  • 8
    • 84861982240 scopus 로고    scopus 로고
    • Bivalent histone modifications in early embryogenesis
    • Vastenhouw NL, Schier AF, (2012) Bivalent histone modifications in early embryogenesis. Curr Opin Cell Biol 24: 374-386
    • (2012) Curr Opin Cell Biol , vol.24 , pp. 374-386
    • Vastenhouw, N.L.1    Schier, A.F.2
  • 9
    • 84857054810 scopus 로고    scopus 로고
    • Factor mediated gene priming in pluripotent stem cells sets the stage for lineage specification
    • Dillon N, (2012) Factor mediated gene priming in pluripotent stem cells sets the stage for lineage specification. BioEssays 34: 194-204
    • (2012) BioEssays , vol.34 , pp. 194-204
    • Dillon, N.1
  • 10
    • 79953163994 scopus 로고    scopus 로고
    • Chromatin states in pluripotent, differentiated, and reprogrammed cells
    • Fisher CL, Fisher AG, (2011) Chromatin states in pluripotent, differentiated, and reprogrammed cells. Curr Opin Genet Dev 21: 140-146
    • (2011) Curr Opin Genet Dev , vol.21 , pp. 140-146
    • Fisher, C.L.1    Fisher, A.G.2
  • 12
  • 16
    • 58049191558 scopus 로고    scopus 로고
    • Chromatin signatures in multipotent human hematopoietic stem cells indicate the fate of bivalent genes during differentiation
    • Cui K, Zang C, Roh TY, Schones DE, Childs RW, Peng W, Zhao K, (2009) Chromatin signatures in multipotent human hematopoietic stem cells indicate the fate of bivalent genes during differentiation. Cell Stem Cell 4: 80-93
    • (2009) Cell Stem Cell , vol.4 , pp. 80-93
    • Cui, K.1    Zang, C.2    Roh, T.Y.3    Schones, D.E.4    Childs, R.W.5    Peng, W.6    Zhao, K.7
  • 17
    • 84875026085 scopus 로고    scopus 로고
    • Dynamic regulation of epigenomic landscapes during hematopoiesis
    • Abraham BJ, Cui K, Tang Q, Zhao K, (2013) Dynamic regulation of epigenomic landscapes during hematopoiesis. BMC Genom 14: 193
    • (2013) BMC Genom , vol.14 , pp. 193
    • Abraham, B.J.1    Cui, K.2    Tang, Q.3    Zhao, K.4
  • 18
    • 51649129596 scopus 로고    scopus 로고
    • Lineage-specific polycomb targets and de novo DNA methylation define restriction and potential of neuronal progenitors
    • Mohn F, Weber M, Rebhan M, Roloff TC, Richter J, Stadler MB, Bibel M, Schubeler D, (2008) Lineage-specific polycomb targets and de novo DNA methylation define restriction and potential of neuronal progenitors. Mol Cell 30: 755-766
    • (2008) Mol Cell , vol.30 , pp. 755-766
    • Mohn, F.1    Weber, M.2    Rebhan, M.3    Roloff, T.C.4    Richter, J.5    Stadler, M.B.6    Bibel, M.7    Schubeler, D.8
  • 19
    • 33750488431 scopus 로고    scopus 로고
    • The genomic landscape of histone modifications in human T cells
    • Roh TY, Cuddapah S, Cui K, Zhao K, (2006) The genomic landscape of histone modifications in human T cells. Proc Natl Acad Sci USA 103: 15782-15787
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 15782-15787
    • Roh, T.Y.1    Cuddapah, S.2    Cui, K.3    Zhao, K.4
  • 22
    • 78449231269 scopus 로고    scopus 로고
    • Multivalent epigenetic marks confer microenvironment-responsive epigenetic plasticity to ovarian cancer cells
    • Bapat SA, Jin V, Berry N, Balch C, Sharma N, Kurrey N, Zhang S, Fang F, Lan X, Li M, et al, (2010) Multivalent epigenetic marks confer microenvironment-responsive epigenetic plasticity to ovarian cancer cells. Epigenetics 5: 716-729
    • (2010) Epigenetics , vol.5 , pp. 716-729
    • Bapat, S.A.1    Jin, V.2    Berry, N.3    Balch, C.4    Sharma, N.5    Kurrey, N.6    Zhang, S.7    Fang, F.8    Lan, X.9    Li, M.10
  • 24
    • 84924939927 scopus 로고    scopus 로고
    • Global analysis of H3K4me3 and H3K27me3 profiles in glioblastoma stem cells and identification of SLC17A7 as a bivalent tumor suppressor gene
    • Lin B, Lee H, Yoon JG, Madan A, Wayner E, Tonning S, Hothi P, Schroeder B, Ulasov I, Foltz G, et al, (2015) Global analysis of H3K4me3 and H3K27me3 profiles in glioblastoma stem cells and identification of SLC17A7 as a bivalent tumor suppressor gene. Oncotarget 6: 5369-5381
    • (2015) Oncotarget , vol.6 , pp. 5369-5381
    • Lin, B.1    Lee, H.2    Yoon, J.G.3    Madan, A.4    Wayner, E.5    Tonning, S.6    Hothi, P.7    Schroeder, B.8    Ulasov, I.9    Foltz, G.10
  • 28
    • 84861870951 scopus 로고    scopus 로고
    • The COMPASS family of histone H3K4 methylases: Mechanisms of regulation in development and disease pathogenesis
    • Shilatifard A, (2012) The COMPASS family of histone H3K4 methylases: mechanisms of regulation in development and disease pathogenesis. Annu Rev Biochem 81: 65-95
    • (2012) Annu Rev Biochem , vol.81 , pp. 65-95
    • Shilatifard, A.1
  • 29
    • 0037082439 scopus 로고    scopus 로고
    • The MT domain of the proto-oncoprotein MLL binds to CpG-containing DNA and discriminates against methylation
    • Birke M, Schreiner S, Garcia-Cuellar MP, Mahr K, Titgemeyer F, Slany RK, (2002) The MT domain of the proto-oncoprotein MLL binds to CpG-containing DNA and discriminates against methylation. Nucleic Acids Res 30: 958-965
    • (2002) Nucleic Acids Res , vol.30 , pp. 958-965
    • Birke, M.1    Schreiner, S.2    Garcia-Cuellar, M.P.3    Mahr, K.4    Titgemeyer, F.5    Slany, R.K.6
  • 30
    • 60149090032 scopus 로고    scopus 로고
    • Alterations of the CxxC domain preclude oncogenic activation of mixed-lineage leukemia 2
    • Bach C, Mueller D, Buhl S, Garcia-Cuellar MP, Slany RK, (2009) Alterations of the CxxC domain preclude oncogenic activation of mixed-lineage leukemia 2. Oncogene 28: 815-823
    • (2009) Oncogene , vol.28 , pp. 815-823
    • Bach, C.1    Mueller, D.2    Buhl, S.3    Garcia-Cuellar, M.P.4    Slany, R.K.5
  • 31
    • 0035976968 scopus 로고    scopus 로고
    • Identification and characterization of the DNA binding domain of CpG-binding protein
    • Lee JH, Voo KS, Skalnik DG, (2001) Identification and characterization of the DNA binding domain of CpG-binding protein. J Biol Chem 276: 44669-44676
    • (2001) J Biol Chem , vol.276 , pp. 44669-44676
    • Lee, J.H.1    Voo, K.S.2    Skalnik, D.G.3
  • 34
    • 79954414897 scopus 로고    scopus 로고
    • Wdr5 mediates self-renewal and reprogramming via the embryonic stem cell core transcriptional network
    • Ang YS, Tsai SY, Lee DF, Monk J, Su J, Ratnakumar K, Ding J, Ge Y, Darr H, Chang B, et al, (2011) Wdr5 mediates self-renewal and reprogramming via the embryonic stem cell core transcriptional network. Cell 145: 183-197
    • (2011) Cell , vol.145 , pp. 183-197
    • Ang, Y.S.1    Tsai, S.Y.2    Lee, D.F.3    Monk, J.4    Su, J.5    Ratnakumar, K.6    Ding, J.7    Ge, Y.8    Darr, H.9    Chang, B.10
  • 36
    • 84874035711 scopus 로고    scopus 로고
    • The trithorax group protein Ash2l is essential for pluripotency and maintaining open chromatin in embryonic stem cells
    • Wan M, Liang J, Xiong Y, Shi F, Zhang Y, Lu W, He Q, Yang D, Chen R, Liu D, et al, (2012) The trithorax group protein Ash2l is essential for pluripotency and maintaining open chromatin in embryonic stem cells. J Biol Chem 288: 5039-5048
    • (2012) J Biol Chem , vol.288 , pp. 5039-5048
    • Wan, M.1    Liang, J.2    Xiong, Y.3    Shi, F.4    Zhang, Y.5    Lu, W.6    He, Q.7    Yang, D.8    Chen, R.9    Liu, D.10
  • 37
    • 1842557785 scopus 로고    scopus 로고
    • Conditional inactivation of the MEN1 gene leads to pancreatic and pituitary tumorigenesis but does not affect normal development of these tissues
    • Biondi CA, Gartside MG, Waring P, Loffler KA, Stark MS, Magnuson MA, Kay GF, Hayward NK, (2004) Conditional inactivation of the MEN1 gene leads to pancreatic and pituitary tumorigenesis but does not affect normal development of these tissues. Mol Cell Biol 24: 3125-3131
    • (2004) Mol Cell Biol , vol.24 , pp. 3125-3131
    • Biondi, C.A.1    Gartside, M.G.2    Waring, P.3    Loffler, K.A.4    Stark, M.S.5    Magnuson, M.A.6    Kay, G.F.7    Hayward, N.K.8
  • 38
    • 79951711112 scopus 로고    scopus 로고
    • Role for Dpy-30 in ES cell-fate specification by regulation of H3K4 methylation within bivalent domains
    • Jiang H, Shukla A, Wang X, Chen WY, Bernstein BE, Roeder RG, (2011) Role for Dpy-30 in ES cell-fate specification by regulation of H3K4 methylation within bivalent domains. Cell 144: 513-525
    • (2011) Cell , vol.144 , pp. 513-525
    • Jiang, H.1    Shukla, A.2    Wang, X.3    Chen, W.Y.4    Bernstein, B.E.5    Roeder, R.G.6
  • 39
    • 34250321317 scopus 로고    scopus 로고
    • Increased apoptosis and skewed differentiation in mouse embryonic stem cells lacking the histone methyltransferase Mll2
    • Lubitz S, Glaser S, Schaft J, Stewart AF, Anastassiadis K, (2007) Increased apoptosis and skewed differentiation in mouse embryonic stem cells lacking the histone methyltransferase Mll2. Mol Biol Cell 18: 2356-2366
    • (2007) Mol Biol Cell , vol.18 , pp. 2356-2366
    • Lubitz, S.1    Glaser, S.2    Schaft, J.3    Stewart, A.F.4    Anastassiadis, K.5
  • 45
    • 84873167174 scopus 로고    scopus 로고
    • RYBP and Cbx7 define specific biological functions of polycomb complexes in mouse embryonic stem cells
    • Morey L, Aloia L, Cozzuto L, Benitah SA, Di Croce L, (2013) RYBP and Cbx7 define specific biological functions of polycomb complexes in mouse embryonic stem cells. Cell Rep 3: 60-69
    • (2013) Cell Rep , vol.3 , pp. 60-69
    • Morey, L.1    Aloia, L.2    Cozzuto, L.3    Benitah, S.A.4    Di Croce, L.5
  • 47
    • 1942503942 scopus 로고    scopus 로고
    • The functions of E(Z)/EZH2-mediated methylation of lysine 27 in histone H3
    • Cao R, Zhang Y, (2004) The functions of E(Z)/EZH2-mediated methylation of lysine 27 in histone H3. Curr Opin Genet Dev 14: 155-164
    • (2004) Curr Opin Genet Dev , vol.14 , pp. 155-164
    • Cao, R.1    Zhang, Y.2
  • 49
    • 79954562232 scopus 로고    scopus 로고
    • Regulating RNA polymerase pausing and transcription elongation in embryonic stem cells
    • Min IM, Waterfall JJ, Core LJ, Munroe RJ, Schimenti J, Lis JT, (2011) Regulating RNA polymerase pausing and transcription elongation in embryonic stem cells. Genes Dev 25: 742-754
    • (2011) Genes Dev , vol.25 , pp. 742-754
    • Min, I.M.1    Waterfall, J.J.2    Core, L.J.3    Munroe, R.J.4    Schimenti, J.5    Lis, J.T.6
  • 54
    • 84855476375 scopus 로고    scopus 로고
    • Oct4 links multiple epigenetic pathways to the pluripotency network
    • Ding J, Xu H, Faiola F, Ma'ayan A, Wang J, (2011) Oct4 links multiple epigenetic pathways to the pluripotency network. Cell Res 22: 155-167
    • (2011) Cell Res , vol.22 , pp. 155-167
    • Ding, J.1    Xu, H.2    Faiola, F.3    Ma'Ayan, A.4    Wang, J.5
  • 55
    • 80052805267 scopus 로고    scopus 로고
    • Histone modification: Cause or cog?
    • Henikoff S, Shilatifard A, (2011) Histone modification: cause or cog? Trends Genet 27: 389-396
    • (2011) Trends Genet , vol.27 , pp. 389-396
    • Henikoff, S.1    Shilatifard, A.2
  • 56
    • 34248169728 scopus 로고    scopus 로고
    • The polycomb group protein Suz12 is required for embryonic stem cell differentiation
    • Pasini D, Bracken AP, Hansen JB, Capillo M, Helin K, (2007) The polycomb group protein Suz12 is required for embryonic stem cell differentiation. Mol Cell Biol 27: 3769-3779
    • (2007) Mol Cell Biol , vol.27 , pp. 3769-3779
    • Pasini, D.1    Bracken, A.P.2    Hansen, J.B.3    Capillo, M.4    Helin, K.5
  • 57
    • 48649091905 scopus 로고    scopus 로고
    • Polycomb repressive complex 2 is dispensable for maintenance of embryonic stem cell pluripotency
    • Chamberlain SJ, Yee D, Magnuson T, (2008) Polycomb repressive complex 2 is dispensable for maintenance of embryonic stem cell pluripotency. Stem Cells 26: 1496-1505
    • (2008) Stem Cells , vol.26 , pp. 1496-1505
    • Chamberlain, S.J.1    Yee, D.2    Magnuson, T.3
  • 58
    • 55949124844 scopus 로고    scopus 로고
    • EZH1 mediates methylation on histone H3 lysine 27 and complements EZH2 in maintaining stem cell identity and executing pluripotency
    • Shen X, Liu Y, Hsu YJ, Fujiwara Y, Kim J, Mao X, Yuan GC, Orkin SH, (2008) EZH1 mediates methylation on histone H3 lysine 27 and complements EZH2 in maintaining stem cell identity and executing pluripotency. Mol Cell 32: 491-502
    • (2008) Mol Cell , vol.32 , pp. 491-502
    • Shen, X.1    Liu, Y.2    Hsu, Y.J.3    Fujiwara, Y.4    Kim, J.5    Mao, X.6    Yuan, G.C.7    Orkin, S.H.8
  • 59
    • 76149142791 scopus 로고    scopus 로고
    • Polycomb complexes act redundantly to repress genomic repeats and genes
    • Leeb M, Pasini D, Novatchkova M, Jaritz M, Helin K, Wutz A, (2010) Polycomb complexes act redundantly to repress genomic repeats and genes. Genes Dev 24: 265-276
    • (2010) Genes Dev , vol.24 , pp. 265-276
    • Leeb, M.1    Pasini, D.2    Novatchkova, M.3    Jaritz, M.4    Helin, K.5    Wutz, A.6
  • 60
    • 0028910338 scopus 로고
    • The eed mutation disrupts anterior mesoderm production in mice
    • Faust C, Schumacher A, Holdener B, Magnuson T, (1995) The eed mutation disrupts anterior mesoderm production in mice. Development 121: 273-285
    • (1995) Development , vol.121 , pp. 273-285
    • Faust, C.1    Schumacher, A.2    Holdener, B.3    Magnuson, T.4
  • 62
    • 8144230178 scopus 로고    scopus 로고
    • Suz12 is essential for mouse development and for EZH2 histone methyltransferase activity
    • Pasini D, Bracken AP, Jensen MR, Lazzerini Denchi E, Helin K, (2004) Suz12 is essential for mouse development and for EZH2 histone methyltransferase activity. EMBO J 23: 4061-4071
    • (2004) EMBO J , vol.23 , pp. 4061-4071
    • Pasini, D.1    Bracken, A.P.2    Jensen, M.R.3    Lazzerini Denchi, E.4    Helin, K.5
  • 63
    • 34447508437 scopus 로고    scopus 로고
    • Ring1B is crucial for the regulation of developmental control genes and PRC1 proteins but not X inactivation in embryonic cells
    • Leeb M, Wutz A, (2007) Ring1B is crucial for the regulation of developmental control genes and PRC1 proteins but not X inactivation in embryonic cells. J Cell Biol 178: 219-229
    • (2007) J Cell Biol , vol.178 , pp. 219-229
    • Leeb, M.1    Wutz, A.2
  • 64
    • 0028923508 scopus 로고
    • Transformation of axial skeleton due to overexpression of bmi-1 in transgenic mice
    • Alkema MJ, van der Lugt NM, Bobeldijk RC, Berns A, van Lohuizen M, (1995) Transformation of axial skeleton due to overexpression of bmi-1 in transgenic mice. Nature 374: 724-727
    • (1995) Nature , vol.374 , pp. 724-727
    • Alkema, M.J.1    Van Der Lugt, N.M.2    Bobeldijk, R.C.3    Berns, A.4    Van Lohuizen, M.5
  • 66
    • 84878267796 scopus 로고    scopus 로고
    • Polycomb complexes in stem cells and embryonic development
    • Aloia L, Di Stefano B, Di Croce L, (2013) Polycomb complexes in stem cells and embryonic development. Development 140: 2525-2534
    • (2013) Development , vol.140 , pp. 2525-2534
    • Aloia, L.1    Di Stefano, B.2    Di Croce, L.3
  • 68
    • 67650725820 scopus 로고    scopus 로고
    • The biology of chromatin remodeling complexes
    • Clapier CR, Cairns BR, (2009) The biology of chromatin remodeling complexes. Annu Rev Biochem 78: 273-304
    • (2009) Annu Rev Biochem , vol.78 , pp. 273-304
    • Clapier, C.R.1    Cairns, B.R.2
  • 70
    • 46149110511 scopus 로고    scopus 로고
    • An RNAi screen of chromatin proteins identifies Tip60-p400 as a regulator of embryonic stem cell identity
    • Fazzio TG, Huff JT, Panning B, (2008) An RNAi screen of chromatin proteins identifies Tip60-p400 as a regulator of embryonic stem cell identity. Cell 134: 162-174
    • (2008) Cell , vol.134 , pp. 162-174
    • Fazzio, T.G.1    Huff, J.T.2    Panning, B.3
  • 71
    • 65249173999 scopus 로고    scopus 로고
    • An embryonic stem cell chromatin remodeling complex, esBAF, is an essential component of the core pluripotency transcriptional network
    • Ho L, Jothi R, Ronan JL, Cui K, Zhao K, Crabtree GR, (2009) An embryonic stem cell chromatin remodeling complex, esBAF, is an essential component of the core pluripotency transcriptional network. Proc Natl Acad Sci USA 106: 5187-5191
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 5187-5191
    • Ho, L.1    Jothi, R.2    Ronan, J.L.3    Cui, K.4    Zhao, K.5    Crabtree, G.R.6
  • 72
    • 62549095522 scopus 로고    scopus 로고
    • SWI/SNF-Brg1 regulates self-renewal and occupies core pluripotency-related genes in embryonic stem cells
    • Kidder BL, Palmer S, Knott JG, (2009) SWI/SNF-Brg1 regulates self-renewal and occupies core pluripotency-related genes in embryonic stem cells. Stem Cells 27: 317-328
    • (2009) Stem Cells , vol.27 , pp. 317-328
    • Kidder, B.L.1    Palmer, S.2    Knott, J.G.3
  • 75
    • 77953120646 scopus 로고    scopus 로고
    • Jarid2 is a PRC2 component in embryonic stem cells required for multi-lineage differentiation and recruitment of PRC1 and RNA Polymerase II to developmental regulators
    • Landeira D, Sauer S, Poot R, Dvorkina M, Mazzarella L, Jorgensen HF, Pereira CF, Leleu M, Piccolo FM, Spivakov M, et al, (2010) Jarid2 is a PRC2 component in embryonic stem cells required for multi-lineage differentiation and recruitment of PRC1 and RNA Polymerase II to developmental regulators. Nat Cell Biol 12: 618-624
    • (2010) Nat Cell Biol , vol.12 , pp. 618-624
    • Landeira, D.1    Sauer, S.2    Poot, R.3    Dvorkina, M.4    Mazzarella, L.5    Jorgensen, H.F.6    Pereira, C.F.7    Leleu, M.8    Piccolo, F.M.9    Spivakov, M.10
  • 76
    • 79961002967 scopus 로고    scopus 로고
    • EsBAF facilitates pluripotency by conditioning the genome for LIF/STAT3 signalling and by regulating polycomb function
    • Ho L, Miller EL, Ronan JL, Ho WQ, Jothi R, Crabtree GR, (2011) esBAF facilitates pluripotency by conditioning the genome for LIF/STAT3 signalling and by regulating polycomb function. Nat Cell Biol 13: 903-913
    • (2011) Nat Cell Biol , vol.13 , pp. 903-913
    • Ho, L.1    Miller, E.L.2    Ronan, J.L.3    Ho, W.Q.4    Jothi, R.5    Crabtree, G.R.6
  • 79
    • 84914164187 scopus 로고    scopus 로고
    • Transcriptional repression by the BRG1-SWI/SNF complex affects the pluripotency of human embryonic stem cells
    • Zhang X, Li B, Li W, Ma L, Zheng D, Li L, Yang W, Chu M, Chen W, Mailman RB, et al, (2014) Transcriptional repression by the BRG1-SWI/SNF complex affects the pluripotency of human embryonic stem cells. Stem Cell Rep 3: 460-474
    • (2014) Stem Cell Rep , vol.3 , pp. 460-474
    • Zhang, X.1    Li, B.2    Li, W.3    Ma, L.4    Zheng, D.5    Li, L.6    Yang, W.7    Chu, M.8    Chen, W.9    Mailman, R.B.10
  • 84
    • 55449092929 scopus 로고    scopus 로고
    • Drosophila Kismet regulates histone H3 lysine 27 methylation and early elongation by RNA polymerase II
    • Srinivasan S, Dorighi KM, Tamkun JW, (2008) Drosophila Kismet regulates histone H3 lysine 27 methylation and early elongation by RNA polymerase II. PLoS Genet 4: e1000217
    • (2008) PLoS Genet , vol.4 , pp. e1000217
    • Srinivasan, S.1    Dorighi, K.M.2    Tamkun, J.W.3
  • 89
    • 0037023681 scopus 로고    scopus 로고
    • Histone H3 lysine 4 methylation disrupts binding of nucleosome remodeling and deacetylase (NuRD) repressor complex
    • Zegerman P, Canas B, Pappin D, Kouzarides T, (2002) Histone H3 lysine 4 methylation disrupts binding of nucleosome remodeling and deacetylase (NuRD) repressor complex. J Biol Chem 277: 11621-11624
    • (2002) J Biol Chem , vol.277 , pp. 11621-11624
    • Zegerman, P.1    Canas, B.2    Pappin, D.3    Kouzarides, T.4
  • 91
    • 84937628573 scopus 로고    scopus 로고
    • Ctbp2 modulates NuRD-mediated deacetylation of H3K27 and facilitates PRC2-mediated H3K27me3 in active embryonic stem cell genes during exit from pluripotency
    • Kim TW, Kang BH, Jang H, Kwak S, Shin J, Kim H, Lee SE, Lee SM, Lee JH, Kim JH, et al, (2015) Ctbp2 modulates NuRD-mediated deacetylation of H3K27 and facilitates PRC2-mediated H3K27me3 in active embryonic stem cell genes during exit from pluripotency. Stem Cells 33: 2442-2455
    • (2015) Stem Cells , vol.33 , pp. 2442-2455
    • Kim, T.W.1    Kang, B.H.2    Jang, H.3    Kwak, S.4    Shin, J.5    Kim, H.6    Lee, S.E.7    Lee, S.M.8    Lee, J.H.9    Kim, J.H.10
  • 92
    • 84861419777 scopus 로고    scopus 로고
    • The chromatin remodeling complex NuRD establishes the poised state of rRNA genes characterized by bivalent histone modifications and altered nucleosome positions
    • Xie W, Ling T, Zhou Y, Feng W, Zhu Q, Stunnenberg HG, Grummt I, Tao W, (2012) The chromatin remodeling complex NuRD establishes the poised state of rRNA genes characterized by bivalent histone modifications and altered nucleosome positions. Proc Natl Acad Sci USA 109: 8161-8166
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 8161-8166
    • Xie, W.1    Ling, T.2    Zhou, Y.3    Feng, W.4    Zhu, Q.5    Stunnenberg, H.G.6    Grummt, I.7    Tao, W.8
  • 96
    • 84866867319 scopus 로고    scopus 로고
    • H2A.Z landscapes and dual modifications in pluripotent and multipotent stem cells underlie complex genome regulatory functions
    • Ku M, Jaffe JD, Koche RP, Rheinbay E, Endoh M, Koseki H, Carr SA, Bernstein BE, (2012) H2A.Z landscapes and dual modifications in pluripotent and multipotent stem cells underlie complex genome regulatory functions. Genome Biol 13: R85
    • (2012) Genome Biol , vol.13 , pp. R85
    • Ku, M.1    Jaffe, J.D.2    Koche, R.P.3    Rheinbay, E.4    Endoh, M.5    Koseki, H.6    Carr, S.A.7    Bernstein, B.E.8
  • 97
    • 84873581550 scopus 로고    scopus 로고
    • H2A.Z facilitates access of active and repressive complexes to chromatin in embryonic stem cell self-renewal and differentiation
    • Hu G, Cui K, Northrup D, Liu C, Wang C, Tang Q, Ge K, Levens D, Crane-Robinson C, Zhao K, (2013) H2A.Z facilitates access of active and repressive complexes to chromatin in embryonic stem cell self-renewal and differentiation. Cell Stem Cell 12: 180-192
    • (2013) Cell Stem Cell , vol.12 , pp. 180-192
    • Hu, G.1    Cui, K.2    Northrup, D.3    Liu, C.4    Wang, C.5    Tang, Q.6    Ge, K.7    Levens, D.8    Crane-Robinson, C.9    Zhao, K.10
  • 99
    • 77954630809 scopus 로고    scopus 로고
    • Distinct histone modifications in stem cell lines and tissue lineages from the early mouse embryo
    • Rugg-Gunn PJ, Cox BJ, Ralston A, Rossant J, (2010) Distinct histone modifications in stem cell lines and tissue lineages from the early mouse embryo. Proc Natl Acad Sci USA 107: 10783-10790
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 10783-10790
    • Rugg-Gunn, P.J.1    Cox, B.J.2    Ralston, A.3    Rossant, J.4
  • 102
    • 84874687019 scopus 로고    scopus 로고
    • Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression
    • Qi LS, Larson MH, Gilbert LA, Doudna JA, Weissman JS, Arkin AP, Lim WA, (2013) Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression. Cell 152: 1173-1183
    • (2013) Cell , vol.152 , pp. 1173-1183
    • Qi, L.S.1    Larson, M.H.2    Gilbert, L.A.3    Doudna, J.A.4    Weissman, J.S.5    Arkin, A.P.6    Lim, W.A.7
  • 104
    • 84898998655 scopus 로고    scopus 로고
    • Direct activation of human and mouse Oct4 genes using engineered TALE and Cas9 transcription factors
    • Hu J, Lei Y, Wong WK, Liu S, Lee KC, He X, You W, Zhou R, Guo JT, Chen X, et al, (2014) Direct activation of human and mouse Oct4 genes using engineered TALE and Cas9 transcription factors. Nucleic Acids Res 42: 4375-4390
    • (2014) Nucleic Acids Res , vol.42 , pp. 4375-4390
    • Hu, J.1    Lei, Y.2    Wong, W.K.3    Liu, S.4    Lee, K.C.5    He, X.6    You, W.7    Zhou, R.8    Guo, J.T.9    Chen, X.10
  • 105
    • 84942793975 scopus 로고    scopus 로고
    • Photoactivatable CRISPR-Cas9 for optogenetic genome editing
    • Nihongaki Y, Kawano F, Nakajima T, Sato M, (2015) Photoactivatable CRISPR-Cas9 for optogenetic genome editing. Nat Biotechnol 33: 755-760
    • (2015) Nat Biotechnol , vol.33 , pp. 755-760
    • Nihongaki, Y.1    Kawano, F.2    Nakajima, T.3    Sato, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.