The trithorax group protein Ash2l is essential for pluripotency and maintaining open chromatin in embryonic stem cells

Journal of Biological Chemistry

Volumn 288, Issue 7, 2013, Pages 5039-5048

  Wan, Ma ^b   Liang, Jiancong ^b   Xiong, Yuanyan ^a   Shi, Fengtao ^b   Zhang, Yi ^b   Lu, Weisi ^a   He, Quanyuan ^b   Yang, Dong ^b   Chen, Rui ^b   Liu, Dan ^b   Barton, Michelle ^b,c   Songyang, Zhou ^a,b  

^a SUN YAT SEN UNIVERSITY   (China)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

^c UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHROMATIN COMPACTION; CORE COMPONENTS; EMBRYONIC DEVELOPMENT; EMBRYONIC STEM CELLS; ES CELLS; PLURIPOTENCY; TRITHORAX;

ALKYLATION; MAMMALS; PROTEINS;

CHROMOSOMES;

ALKALINE PHOSPHATASE; MESSENGER RNA; MYC PROTEIN; OCTAMER TRANSCRIPTION FACTOR 4; REGULATOR PROTEIN; RETINOBLASTOMA BINDING PROTEIN; RETINOBLASTOMA BINDING PROTEIN 5; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR NANOG; TRITHORAX ABSENT SMALL HOMEOTIC 2L; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING SITE; CELL DIFFERENTIATION; CELL PLURIPOTENCY; CELL STRUCTURE; CELLULAR DISTRIBUTION; CELLULAR PARAMETERS; CHROMATIN IMMUNOPRECIPITATION; CHROMATIN REMODELER CDH1 GENE; CHROMATIN REMODELER CDH7 GENE; CHROMATIN STRUCTURE; CONTROLLED STUDY; EMBRYO; EMBRYONIC STEM CELL; ENZYME ACTIVITY; EPIGENETICS; GENE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE SILENCING; H3K9 DEMETHYLASE KDM4C GENE; HISTONE METHYLATION; IN VIVO STUDY; MOUSE; NANOG GENE; NONHUMAN; NUCLEOTIDE SEQUENCE; OCT4 GENE; ONCOGENE C MYC; OPEN CHROMATIN; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RNA INTERFERENCE; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS; UPREGULATION;

ANIMALS; CELL DIFFERENTIATION; CHROMATIN; CHROMATIN IMMUNOPRECIPITATION; DNA-BINDING PROTEINS; EMBRYONIC STEM CELLS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENOME; HISTONES; METHYLATION; MICE; MICROSCOPY, FLUORESCENCE; MODELS, BIOLOGICAL; MYELOID-LYMPHOID LEUKEMIA PROTEIN; NUCLEAR PROTEINS; PLURIPOTENT STEM CELLS; RNA INTERFERENCE; TRANSCRIPTION FACTORS;

EID: 84874035711     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.424515     Document Type: Article

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