The chromodomain helicase Chd4 is required for Polycomb-mediated inhibition of astroglial differentiation

EMBO Journal

Volumn 32, Issue 11, 2013, Pages 1598-1612

  Sparmann, Anke ^a   Xie, Yunli ^b   Verhoeven, Els ^a   Vermeulen, Michiel ^c,d   Lancini, Cesare ^a   Gargiulo, Gaetano ^a   Hulsman, Danielle ^a   Mann, Matthias ^c   Knoblich, Juergen A ^b   Van Lohuizen, Maarten ^a,d  

^a NETHERLANDS CANCER INSTITUTE   (Netherlands)

^b INSTITUTE OF MOLECULAR BIOTECHNOLOGY   (Austria)

^c MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

^d UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

Astrogenesis; Chd4; differentiation; neural stem cells; polycomb

Indexed keywords

CHROMODOMAIN HELICASE DNA BINDING PROTEIN 4; HELICASE; POLYCOMB GROUP PROTEIN; TRANSCRIPTION FACTOR EZH2; UNCLASSIFIED DRUG;

ARTICLE; ASTROCYTE; CONTROLLED STUDY; ENZYME ANALYSIS; IN VIVO STUDY; NEOCORTEX; NERVE CELL DIFFERENTIATION; NERVOUS SYSTEM DEVELOPMENT; NEURAL STEM CELL; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN INTERACTION;

ANIMALS; ASTROCYTES; CELL DIFFERENTIATION; CELL LINE; CHROMATIN IMMUNOPRECIPITATION; DNA HELICASES; EMBRYO, MAMMALIAN; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HISTONES; MICE; MICE, INBRED C57BL; NERVE TISSUE PROTEINS; NEURAL STEM CELLS; NUCLEAR PROTEINS; POLYCOMB REPRESSIVE COMPLEX 2; POLYCOMB-GROUP PROTEINS; PREGNANCY; PROMOTER REGIONS, GENETIC;

EID: 84878533080     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2013.93     Document Type: Article

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