Stem Cell-Specific Mechanisms Ensure Genomic Fidelity within HSCs and upon Aging of HSCs

Cell Reports

Volumn 13, Issue 11, 2015, Pages 2412-2424

  Moehrle, Bettina M ^a   Nattamai, Kalpana ^b   Brown, Andreas ^a   Florian, Maria C ^a   Ryan, Marnie ^b   Vogel, Mona ^a   Bliederhaeuser, Corinna ^a   Soller, Karin ^a   Prows, Daniel R ^b   Abdollahi, Amir ^c,d   Schleimer, David ^b   Walter, Dagmar ^e   Milsom, Michael D ^c,e   Stambrook, Peter ^f   Porteus, Matthew ^g   Geiger, Hartmut ^a,b  

^a UNIVERSITY OF ULM   (Germany)

^b CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^c GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^d UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

^e Heidelberg Institute for Stem Cell Technology and Eexperimental Medicine   (Germany)

^f UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^g STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ZINC FINGER NUCLEASE; CHECKPOINT KINASE 2; CHEK2 PROTEIN, MOUSE; DEOXYRIBONUCLEASE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL AGING; CELL CYCLE REGULATION; CELL DIFFERENTIATION; CELL PROTECTION; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; DOUBLE STRANDED DNA BREAK; G1 PHASE CELL CYCLE CHECKPOINT; GENE MUTATION; GENOMICS; HEMATOPOIETIC STEM CELL; IRRADIATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; AGING; ALLOTRANSPLANTATION; AMINO ACID SEQUENCE; ANIMAL; BONE MARROW CELL; BONE MARROW TRANSPLANTATION; C57BL MOUSE; CELL CULTURE; CYTOLOGY; GAMMA RADIATION; GENETICS; GENOME; HETEROZYGOSITY LOSS; METABOLISM; MUTATION; RADIATION RESPONSE; S PHASE CELL CYCLE CHECKPOINT; WHOLE BODY RADIATION;

AGING; AMINO ACID SEQUENCE; ANIMALS; APOPTOSIS; BONE MARROW CELLS; BONE MARROW TRANSPLANTATION; CELLS, CULTURED; CHECKPOINT KINASE 2; DNA DAMAGE; ENDODEOXYRIBONUCLEASES; G1 PHASE CELL CYCLE CHECKPOINTS; GAMMA RAYS; GENOME; HEMATOPOIETIC STEM CELLS; LOSS OF HETEROZYGOSITY; MICE; MICE, INBRED C57BL; MUTATION; S PHASE CELL CYCLE CHECKPOINTS; TRANSPLANTATION, HOMOLOGOUS; WHOLE-BODY IRRADIATION;

EID: 84952870312     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2015.11.030     Document Type: Article

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