Branched-chain amino acid catabolism is a conserved regulator of physiological ageing

Nature Communications

Volumn 6, Issue , 2015, Pages

  Mansfeld, Johannes ^a,b,c,d   Urban, Nadine ^c   Priebe, Steffen ^d,e,f   Groth, Marco ^d,e   Frahm, Christiane ^d,g   Hartmann, Nils ^d,e   Gebauer, Juliane ^c,d   Ravichandran, Meenakshi ^a   Dommaschk, Anne ^c,i   Schmeisser, Sebastian ^c,j   Kuhlow, Doreen ^c,d,h   Monajembashi, Shamci ^e   Bremer Streck, Sibylle ^c   Hemmerich, Peter ^d,e   Kiehntopf, Michael ^c   Zamboni, Nicola ^a   Englert, Christoph ^c,d,e   Guthke, Reinhard ^d,f   Kaleta, Christoph ^c,d,k   Platzer, Matthias ^d,e   Suhnel, Jurgen ^d,e   Witte, Otto W ^d,g   Zarse, Kim ^a,c,d   Ristow, Michael ^a,b,c,d   more..

^a ETH ZURICH   (Switzerland)

^b Deutsche Forschungsgemeinschaft   (Germany)

^c FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

^d BMBF   (Germany)

^e FRITZ LIPMANN INSTITUTE   (Germany)

^f HANS KNÖLL INSTITUTE   (Germany)

^g JENA UNIVERSITY HOSPITAL   (Germany)

^h GERMAN INSTITUTE OF HUMAN NUTRITION   (Germany)

ⁱ HANNOVER MEDICAL SCHOOL   (Germany)

^j MCGILL UNIVERSITY   (Canada)

^k UNIVERSITY OF KIEL   (Germany)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; BRANCHED CHAIN AMINO ACID; DAF 1 PROTEIN; DAF 16 PROTEIN; DAF 4 PROTEIN; DAF 7 PROTEIN; GLUTAMIC ACID; GLUTAMINE; HEAT SHOCK TRANSCRIPTION FACTOR 1; ISOLEUCINE; LET 363 PROTEIN; LEUCINE; MAMMALIAN TARGET OF RAPAMYCIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR FOXO; TRANSCRIPTION FACTOR HLH 15; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; VALINE; AMINOTRANSFERASE; BRANCHED-CHAIN-AMINO-ACID TRANSAMINASE; CAENORHABDITIS ELEGANS PROTEIN;

AGING; AMINO ACID; CATABOLISM; CYPRINID; ENZYME ACTIVITY; GENE EXPRESSION; NEMATODE; PHYSIOLOGY; RODENT;

ADULT; AGING; AMINO ACID METABOLISM; ARTICLE; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; ENZYME ACTIVATION; EPISTASIS; FERTILITY; GENE EXPRESSION; GENE IDENTIFICATION; GENETIC TRANSCRIPTION; HYPOTHALAMUS; LIFESPAN; MOUSE; MUS MUSCULUS; NEXT GENERATION SEQUENCING; NONHUMAN; PROMOTER REGION; RNA INTERFERENCE; RNA SEQUENCE; SIGNAL TRANSDUCTION; UPREGULATION; YOUNG ADULT; ZEBRA FISH; ANIMAL; C57BL MOUSE; FEMALE; GENETICS; GROWTH, DEVELOPMENT AND AGING; LONGEVITY; MALE; METABOLISM;

CAENORHABDITIS ELEGANS; DANIO RERIO; MUS; NEMATODA; RODENTIA;

AGING; AMINO ACIDS, BRANCHED-CHAIN; ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; FEMALE; LONGEVITY; MALE; MICE; MICE, INBRED C57BL; TRANSAMINASES; ZEBRAFISH;

EID: 84948844004     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms10043     Document Type: Article

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