A Comprehensive Analysis of Replicative Lifespan in 4,698 Single-Gene Deletion Strains Uncovers Conserved Mechanisms of Aging

Cell Metabolism

Volumn 22, Issue 5, 2015, Pages 895-906

  McCormick, Mark A ^a   Delaney, Joe R ^b   Tsuchiya, Mitsuhiro ^a   Tsuchiyama, Scott ^a   Shemorry, Anna ^b   Sim, Sylvia ^b   Chou, Annie Chia Zong ^b   Ahmed, Umema ^b   Carr, Daniel ^b   Murakami, Christopher J ^b   Schleit, Jennifer ^b   Sutphin, George L ^b   Wasko, Brian M ^b   Bennett, Christopher F ^b   Wang, Adrienne M ^b   Olsen, Brady ^b   Beyer, Richard P ^b   Bammler, Theodor K ^b   Prunkard, Donna ^b   Johnson, Simon C ^b   Pennypacker, Juniper K ^a   An, Elroy ^b   Anies, Arieanna ^a   Castanza, Anthony S ^b   Choi, Eunice ^b   Dang, Nick ^b   Enerio, Shiena ^a   Fletcher, Marissa ^b   Fox, Lindsay ^c   Goswami, Sarani ^b   Higgins, Sean A ^b   Holmberg, Molly A ^b   Hu, Di ^b   Hui, Jessica ^b   Jelic, Monika ^b   Jeong, Ki Soo ^b   Johnston, Elijah ^b   Kerr, Emily O ^b   Kim, Jin ^b   Kim, Diana ^b   Kirkland, Katie ^b   Klum, Shannon ^b   Kotireddy, Soumya ^c   Liao, Eric ^b   Lim, Michael ^b   Lin, Michael S ^b   Lo, Winston C ^b   Lockshon, Dan ^a   Miller, Hillary A ^b   Moller, Richard M ^c   Muller, Brian ^b   Oakes, Jonathan ^b   Pak, Diana N ^c   Peng, Zhao Jun ^b   Pham, Kim M ^c   Pollard, Tom G ^b   Pradeep, Prarthana ^b   Pruett, Dillon ^b   Rai, Dilreet ^b   Robison, Brett ^a   Rodriguez, Ariana A ^a   Ros, Bopharoth ^b   Sage, Michael ^b   Singh, Manpreet K ^b   Smith, Erica D ^c   Snead, Katie ^b   Solanky, Amrita ^b   Spector, Benjamin L ^b   Steffen, Kristan K ^b   Tchao, Bie Nga ^b   Ting, Marc K ^a   Vander Wende, Helen ^b   Wang, Dennis ^b   Welton, K Linnea ^b   Westman, Eric A ^b   Brem, Rachel B ^a   Liu, Xin Guang ^d   Suh, Yousin ^d,e   Zhou, Zhongjun ^f   Kaeberlein, Matt ^b   Kennedy, Brian K ^a,c   more..

^a BUCK INSTITUTE FOR RESEARCH ON AGING   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^d GUANGDONG MEDICAL UNIVERSITY   (China)

^e ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^f UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

MAMMALIAN TARGET OF RAPAMYCIN; PROTEASOME; TRANSFER RNA; BASIC LEUCINE ZIPPER TRANSCRIPTION FACTOR; GCN4 PROTEIN, S CEREVISIAE; LOS1 PROTEIN, S CEREVISIAE; NUCLEOPORIN; SACCHAROMYCES CEREVISIAE PROTEIN; TARGET OF RAPAMYCIN KINASE;

AGING; ARTICLE; CAENORHABDITIS ELEGANS; CHEMICAL MODIFICATION; CITRIC ACID CYCLE; DNA DAMAGE; FUNGAL GENE; GENE CLUSTER; GENE DELETION; LIFESPAN; LOS1 GENE; MANNOSYLATION; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; REPLICATIVE LIFESPAN; RNA TRANSLATION; SACCHAROMYCES CEREVISIAE; ANIMAL; ANTAGONISTS AND INHIBITORS; CALORIC RESTRICTION; GENE EXPRESSION REGULATION; GENETICS; GENOME; LONGEVITY; METABOLISM; PATHOLOGY;

AGING; ANIMALS; BASIC-LEUCINE ZIPPER TRANSCRIPTION FACTORS; CAENORHABDITIS ELEGANS; CALORIC RESTRICTION; DNA DAMAGE; GENE DELETION; GENE EXPRESSION REGULATION; GENOME; LONGEVITY; NUCLEAR PORE COMPLEX PROTEINS; RNA, TRANSFER; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; TOR SERINE-THREONINE KINASES;

EID: 84942943828     PISSN: 15504131     EISSN: 19327420     Source Type: Journal    
DOI: 10.1016/j.cmet.2015.09.008     Document Type: Article

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