Neuronal ROS signaling rather than AMPK/sirtuin-mediated energy sensing links dietary restriction to lifespan extension

Molecular Metabolism

Volumn 2, Issue 2, 2013, Pages 92-102

  Schmeisser, Sebastian ^a,b   Priebe, Steffen ^c   Groth, Marco ^b   Monajembashi, Shamci ^b   Hemmerich, Peter ^b   Guthke, Reinhard ^c   Platzer, Matthias ^b   Ristow, Michael ^a,d,e  

^a FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

^b FRITZ LIPMANN INSTITUTE   (Germany)

^c HANS KNÖLL INSTITUTE   (Germany)

^d ETH ZURICH   (Switzerland)

^e GERMAN INSTITUTE OF HUMAN NUTRITION   (Germany)

Author keywords

Aging; Caenorhabditis elegans; Dietary restriction; Mitochondria; Mitohormesis; Reactive oxygen species; Redox signaling

Indexed keywords

ISOPROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN AAK 2; PROTEIN PMK 1; PROTEIN SKN 1; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SIRTUIN; SIRTUIN 2; TRANSCRIPTION FACTOR DAF 16; TRANSCRIPTION FACTOR FOXO; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG;

ARTICLE; BRAIN NERVE CELL; CAENORHABDITIS ELEGANS; CELLULAR STRESS RESPONSE; DIET RESTRICTION; ENERGY METABOLISM; ENZYME ACTIVITY; ENZYME INHIBITION; FOOD INTAKE; LIFE EXTENSION; LONGEVITY; MITOCHONDRIAL RESPIRATION; NEMATODE; NONHUMAN; PHYSICAL ACTIVITY; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

CAENORHABDITIS ELEGANS; NEMATODA;

EID: 84877681309     PISSN: 22128778     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molmet.2013.02.002     Document Type: Article

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