-
1
-
-
84866985855
-
Targeting the TGFbeta signalling pathway in disease
-
Akhurst RJ, Hata A (2012). Targeting the TGFbeta signalling pathway in disease. Nat Rev Drug Discov, 11, 790-811.
-
(2012)
Nat Rev Drug Discov
, vol.11
, pp. 790-811
-
-
Akhurst, R.J.1
Hata, A.2
-
2
-
-
0028953810
-
Transforming growth factor beta and cell cycle regulation
-
Alexandrow MG, Moses HL (1995). Transforming growth factor beta and cell cycle regulation. Cancer Res, 55, 1452-7.
-
(1995)
Cancer Res
, vol.55
, pp. 1452-1457
-
-
Alexandrow, M.G.1
Moses, H.L.2
-
3
-
-
78649986150
-
TGFbeta Receptor Inhibitors Target the CD44(high)/Id1(high) Glioma-Initiating Cell Population in Human Glioblastoma
-
Anido J, Saez-Borderias A, Gonzalez-Junca A, et al (2010). TGFbeta Receptor Inhibitors Target the CD44(high)/Id1(high) Glioma-Initiating Cell Population in Human Glioblastoma. Cancer Cell, 18, 655-68.
-
(2010)
Cancer Cell
, vol.18
, pp. 655-668
-
-
Anido, J.1
Saez-Borderias, A.2
Gonzalez-Junca, A.3
-
4
-
-
0037439630
-
Making sense of latent TGFbeta activation
-
Annes JP, Munger JS, Rifkin DB (2003). Making sense of latent TGFbeta activation. J Cell Sci, 116, 217-24.
-
(2003)
J Cell Sci
, vol.116
, pp. 217-224
-
-
Annes, J.P.1
Munger, J.S.2
Rifkin, D.B.3
-
5
-
-
0031964370
-
Endogenous expression of transforming growth factor beta1 inhibits growth and tumorigenicity and enhances Fas-mediated apoptosis in a murine high-grade glioma model
-
Ashley DM, Kong FM, Bigner DD, et al (1998). Endogenous expression of transforming growth factor beta1 inhibits growth and tumorigenicity and enhances Fas-mediated apoptosis in a murine high-grade glioma model. Cancer Res, 58, 302-9.
-
(1998)
Cancer Res
, vol.58
, pp. 302-309
-
-
Ashley, D.M.1
Kong, F.M.2
Bigner, D.D.3
-
6
-
-
84899657374
-
IGF binding proteins in cancer: mechanistic and clinical insights
-
Baxter RC (2014). IGF binding proteins in cancer: mechanistic and clinical insights. Nat Rev Cancer, 14, 329-41.
-
(2014)
Nat Rev Cancer
, vol.14
, pp. 329-341
-
-
Baxter, R.C.1
-
7
-
-
84947706657
-
Immune Privilege of the Brain. In 'Neuroinflammation and CNS Disorders'
-
Eds John Wiley & Sons, Ltd
-
Bechmann I, Woodroofe N (2014). Immune Privilege of the Brain. In 'Neuroinflammation and CNS Disorders', Eds John Wiley & Sons, Ltd, 1-8.
-
(2014)
, pp. 1-8
-
-
Bechmann, I.1
Woodroofe, N.2
-
8
-
-
84870439234
-
The cancer stem cell subtype determines immune infiltration of glioblastoma
-
Beier CP, Kumar P, Meyer K, et al (2012). The cancer stem cell subtype determines immune infiltration of glioblastoma. Stem Cells Dev, 21, 2753-61.
-
(2012)
Stem Cells Dev
, vol.21
, pp. 2753-2761
-
-
Beier, C.P.1
Kumar, P.2
Meyer, K.3
-
9
-
-
22144494707
-
Integrin alphaVbeta3 contains a cell surface receptor site for thyroid hormone that is linked to activation of mitogen-activated protein kinase and induction of angiogenesis
-
Bergh JJ, Lin HY, Lansing L, et al (2005). Integrin alphaVbeta3 contains a cell surface receptor site for thyroid hormone that is linked to activation of mitogen-activated protein kinase and induction of angiogenesis. Endocrinol, 146, 2864-71.
-
(2005)
Endocrinol
, vol.146
, pp. 2864-2871
-
-
Bergh, J.J.1
Lin, H.Y.2
Lansing, L.3
-
10
-
-
79958849271
-
Heterogeneity maintenance in glioblastoma: a social network
-
Bonavia R, Inda MM, Cavenee WK, et al (2011). Heterogeneity maintenance in glioblastoma: a social network. Cancer Res, 71, 4055-60.
-
(2011)
Cancer Res
, vol.71
, pp. 4055-4060
-
-
Bonavia, R.1
Inda, M.M.2
Cavenee, W.K.3
-
11
-
-
33846821916
-
High TGFbeta-Smad activity confers poor prognosis in glioma patients and promotes cell proliferation depending on the methylation of the PDGF-B gene
-
Bruna A, Darken RS, Rojo F, et al (2007). High TGFbeta-Smad activity confers poor prognosis in glioma patients and promotes cell proliferation depending on the methylation of the PDGF-B gene. Cancer Cell, 11, 147-60.
-
(2007)
Cancer Cell
, vol.11
, pp. 147-160
-
-
Bruna, A.1
Darken, R.S.2
Rojo, F.3
-
12
-
-
84876487189
-
Targeting cancer stem cells for treatment of glioblastoma multiforme
-
Cho DY, Lin SZ, Yang WK, et al (2013). Targeting cancer stem cells for treatment of glioblastoma multiforme. Cell Transplant, 22, 731-9.
-
(2013)
Cell Transplant
, vol.22
, pp. 731-739
-
-
Cho, D.Y.1
Lin, S.Z.2
Yang, W.K.3
-
13
-
-
84861557472
-
Involvement of the TGFβ pathway in the regulation of α5β1 integrins by caveolin-1 in human glioblastoma
-
Cosset EC, Godet J, Entz-Werle N, et al (2012). Involvement of the TGFβ pathway in the regulation of α5β1 integrins by caveolin-1 in human glioblastoma. Int J Cancer, 131, 601-11.
-
(2012)
Int J Cancer
, vol.131
, pp. 601-611
-
-
Cosset, E.C.1
Godet, J.2
Entz-Werle, N.3
-
14
-
-
35348866157
-
Integrins: molecular determinants of glioma invasion
-
D'Abaco GM, Kaye AH (2007). Integrins: molecular determinants of glioma invasion. J Clin Neurosci, 14, 1041-8.
-
(2007)
J Clin Neurosci
, vol.14
, pp. 1041-1048
-
-
D'Abaco, G.M.1
Kaye, A.H.2
-
15
-
-
84874427698
-
Nodal promotes glioblastoma cell growth
-
De Silva T, Ye G, Liang YY, et al (2012). Nodal promotes glioblastoma cell growth. Front Endocrinol (Lausanne), 3, 59.
-
(2012)
Front Endocrinol (Lausanne)
, vol.3
, pp. 59
-
-
De Silva, T.1
Ye, G.2
Liang, Y.Y.3
-
16
-
-
84940971189
-
TGF-beta antibody uptake in recurrent high grade glioma imaged with 89Zr-fresolimumab PET
-
den Hollander MW, Bensch F, Glaudemans AW, et al (2015). TGF-beta antibody uptake in recurrent high grade glioma imaged with 89Zr-fresolimumab PET. J Nucl Med.
-
(2015)
J Nucl Med
-
-
den Hollander, M.W.1
Bensch, F.2
Glaudemans, A.W.3
-
17
-
-
84867571044
-
Transcriptional profiling of human glioblastoma vessels indicates a key role of VEGF-A and TGFβ2 in vascular abnormalization
-
Dieterich LC, Mellberg S, Langenkamp E, et al (2012). Transcriptional profiling of human glioblastoma vessels indicates a key role of VEGF-A and TGFβ2 in vascular abnormalization. J Pathol, 228, 378-90.
-
(2012)
J Pathol
, vol.228
, pp. 378-390
-
-
Dieterich, L.C.1
Mellberg, S.2
Langenkamp, E.3
-
18
-
-
0028906190
-
Processing of transforming growth factor beta 1 precursor by human furin convertase
-
Dubois CM, Laprise MH, Blanchette F, et al (1995). Processing of transforming growth factor beta 1 precursor by human furin convertase. J Biol Chem, 270, 10618-24.
-
(1995)
J Biol Chem
, vol.270
, pp. 10618-10624
-
-
Dubois, C.M.1
Laprise, M.H.2
Blanchette, F.3
-
19
-
-
84899886083
-
Cilengitide treatment of newly diagnosed glioblastoma patients does not alter patterns of progression
-
Eisele G, Wick A, Eisele AC, et al (2014). Cilengitide treatment of newly diagnosed glioblastoma patients does not alter patterns of progression. J Neurooncol, 117, 141-5.
-
(2014)
J Neurooncol
, vol.117
, pp. 141-145
-
-
Eisele, G.1
Wick, A.2
Eisele, A.C.3
-
20
-
-
84922257150
-
Adult Neurogenesis in Humans-Common and Unique Traits in Mammals
-
Ernst A, Frisen J (2015). Adult Neurogenesis in Humans-Common and Unique Traits in Mammals. PLoS Biol, 13, 1002045.
-
(2015)
PLoS Biol
, vol.13
-
-
Ernst, A.1
Frisen, J.2
-
21
-
-
61749086821
-
Transforming growth factor-beta1 increases cell migration and beta1 integrin up-regulation in human lung cancer cells
-
Fong YC, Hsu SF, Wu CL, et al (2009). Transforming growth factor-beta1 increases cell migration and beta1 integrin up-regulation in human lung cancer cells. Lung Cancer, 64, 13-21.
-
(2009)
Lung Cancer
, vol.64
, pp. 13-21
-
-
Fong, Y.C.1
Hsu, S.F.2
Wu, C.L.3
-
22
-
-
5644248080
-
RNA interference targeting transforming growth factor-beta enhances NKG2Dmediated antiglioma immune response, inhibits glioma cell migration and invasiveness, and abrogates tumorigenicity in vivo
-
Friese MA, Wischhusen J, Wick W, et al (2004). RNA interference targeting transforming growth factor-beta enhances NKG2Dmediated antiglioma immune response, inhibits glioma cell migration and invasiveness, and abrogates tumorigenicity in vivo. Cancer Res, 64, 7596-603.
-
(2004)
Cancer Res
, vol.64
, pp. 7596-7603
-
-
Friese, M.A.1
Wischhusen, J.2
Wick, W.3
-
23
-
-
0037007226
-
Balancing the activation state of the endothelium via two distinct TGFbeta type I receptors
-
Goumans MJ, Valdimarsdottir G, Itoh S, et al (2002). Balancing the activation state of the endothelium via two distinct TGFbeta type I receptors. Embo J, 21, 1743-53.
-
(2002)
Embo J
, vol.21
, pp. 1743-1753
-
-
Goumans, M.J.1
Valdimarsdottir, G.2
Itoh, S.3
-
24
-
-
0030273439
-
Bone morphogenetic proteins promote astroglial lineage commitment by mammalian subventricular zone progenitor cells
-
Gross RE, Mehler MF, Mabie PC, et al (1996). Bone morphogenetic proteins promote astroglial lineage commitment by mammalian subventricular zone progenitor cells. Neuron, 17, 595-606.
-
(1996)
Neuron
, vol.17
, pp. 595-606
-
-
Gross, R.E.1
Mehler, M.F.2
Mabie, P.C.3
-
25
-
-
5044238876
-
Integrin signalling during tumour progression
-
Guo W, Giancotti FG (2004). Integrin signalling during tumour progression. Nat Rev Mol Cell Biol, 5, 816-26.
-
(2004)
Nat Rev Mol Cell Biol
, vol.5
, pp. 816-826
-
-
Guo, W.1
Giancotti, F.G.2
-
26
-
-
79952284127
-
Hallmarks of cancer: the next generation
-
Hanahan D, Weinberg RA (2011). Hallmarks of cancer: the next generation. Cell, 144, 646-74.
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
27
-
-
84898900858
-
Immune privilege of the CNS is not the consequence of limited antigen sampling
-
Harris MG, Hulseberg P, Ling C, et al (2014). Immune privilege of the CNS is not the consequence of limited antigen sampling. Sci Rep, 4.
-
(2014)
Sci Rep
, pp. 4
-
-
Harris, M.G.1
Hulseberg, P.2
Ling, C.3
-
28
-
-
34547187636
-
Inhibition of TGF-beta2 with AP 12009 in recurrent malignant gliomas: from preclinical to phase I/II studies
-
Hau P, Jachimczak P, Schlingensiepen R, et al (2007). Inhibition of TGF-beta2 with AP 12009 in recurrent malignant gliomas: from preclinical to phase I/II studies. Oligonucleotides, 17, 201-12.
-
(2007)
Oligonucleotides
, vol.17
, pp. 201-212
-
-
Hau, P.1
Jachimczak, P.2
Schlingensiepen, R.3
-
29
-
-
0024788078
-
Transforming growth factor-beta switches the pattern of integrins expressed in MG-63 human osteosarcoma cells and causes a selective loss of cell adhesion to laminin
-
Heino J, Massague J (1989). Transforming growth factor-beta switches the pattern of integrins expressed in MG-63 human osteosarcoma cells and causes a selective loss of cell adhesion to laminin. J Biol Chem, 264, 21806-11.
-
(1989)
J Biol Chem
, vol.264
, pp. 21806-21811
-
-
Heino, J.1
Massague, J.2
-
30
-
-
0038717313
-
Interaction of transforming growth factor-beta (TGF-beta) and epidermal growth factor (EGF) in human glioma cells
-
Held-Feindt J, Lutjohann B, Ungefroren H, et al (2003). Interaction of transforming growth factor-beta (TGF-beta) and epidermal growth factor (EGF) in human glioma cells. J Neurooncol, 63, 117-27.
-
(2003)
J Neurooncol
, vol.63
, pp. 117-127
-
-
Held-Feindt, J.1
Lutjohann, B.2
Ungefroren, H.3
-
31
-
-
0024240376
-
Type beta transforming growth factor and epidermal growth factor suppress the plasminogen activator activity in a human glioblastoma cell line
-
Helseth E, Dalen A, Unsgaard G, et al (1988). Type beta transforming growth factor and epidermal growth factor suppress the plasminogen activator activity in a human glioblastoma cell line. J Neurooncol, 6, 277-83.
-
(1988)
J Neurooncol
, vol.6
, pp. 277-283
-
-
Helseth, E.1
Dalen, A.2
Unsgaard, G.3
-
32
-
-
84866900231
-
Matrix control of transforming growth factor-β function
-
Horiguchi M, Ota M, Rifkin DB (2012). Matrix control of transforming growth factor-β function. J Biochem, 152, 321-9.
-
(2012)
J Biochem
, vol.152
, pp. 321-329
-
-
Horiguchi, M.1
Ota, M.2
Rifkin, D.B.3
-
33
-
-
70350497349
-
Autocrine TGF-β signaling maintains tumorigenicity of glioma-initiating cells through sry-related HMG-Box factors
-
Ikushima H, Todo T, Ino Y, et al (2009). Autocrine TGF-β signaling maintains tumorigenicity of glioma-initiating cells through sry-related HMG-Box factors. Cell Stem Cell, 5, 504-14.
-
(2009)
Cell Stem Cell
, vol.5
, pp. 504-514
-
-
Ikushima, H.1
Todo, T.2
Ino, Y.3
-
34
-
-
78149464441
-
Molecular imaging of glioblastoma multiforme using anti-insulin-like growth factor-binding protein-7 single-domain antibodies
-
Iqbal U, Albaghdadi H, Luo Y, et al (2010). Molecular imaging of glioblastoma multiforme using anti-insulin-like growth factor-binding protein-7 single-domain antibodies. British J Cancer, 103, 1606-16.
-
(2010)
British J Cancer
, vol.103
, pp. 1606-1616
-
-
Iqbal, U.1
Albaghdadi, H.2
Luo, Y.3
-
35
-
-
0029925720
-
Gene expression of neural cell adhesion molecule L1 in malignant gliomas and biological significance of L1 in glioma invasion
-
Izumoto S, Ohnishi T, Arita N, et al (1996). Gene expression of neural cell adhesion molecule L1 in malignant gliomas and biological significance of L1 in glioma invasion. Cancer Res, 56, 1440-4.
-
(1996)
Cancer Res
, vol.56
, pp. 1440-1444
-
-
Izumoto, S.1
Ohnishi, T.2
Arita, N.3
-
36
-
-
77955658133
-
Prognostic significance and mechanism of Treg infiltration in human brain tumors
-
Jacobs JF, Idema AJ, Bol KF, et al (2010). Prognostic significance and mechanism of Treg infiltration in human brain tumors. J Neuroimmunol, 225, 195-9.
-
(2010)
J Neuroimmunol
, vol.225
, pp. 195-199
-
-
Jacobs, J.F.1
Idema, A.J.2
Bol, K.F.3
-
37
-
-
84882590099
-
Epidemiology of primary CNS tumors in Iran: a systematic review
-
Jazayeri SB, Rahimi-Movaghar V, Shokraneh F, et al (2013). Epidemiology of primary CNS tumors in Iran: a systematic review. Asian Pac J Cancer Prev, 14, 3979-85.
-
(2013)
Asian Pac J Cancer Prev
, vol.14
, pp. 3979-3985
-
-
Jazayeri, S.B.1
Rahimi-Movaghar, V.2
Shokraneh, F.3
-
38
-
-
84919949972
-
TGF-[beta] is an inducer of ZEB1-dependent mesenchymal transdifferentiation in glioblastoma that is associated with tumor invasion
-
Joseph JV, Conroy S, Tomar T, et al (2014). TGF-[beta] is an inducer of ZEB1-dependent mesenchymal transdifferentiation in glioblastoma that is associated with tumor invasion. Cell Death Dis, 5, 1443.
-
(2014)
Cell Death Dis
, vol.5
, pp. 1443
-
-
Joseph, J.V.1
Conroy, S.2
Tomar, T.3
-
39
-
-
84867530190
-
TGF beta signaling and its role in glioma pathogenesis
-
Kaminska B, Kocyk M, Kijewska M (2013). TGF beta signaling and its role in glioma pathogenesis. Adv Exp Med Biol, 986, 171-87.
-
(2013)
Adv Exp Med Biol
, vol.986
, pp. 171-187
-
-
Kaminska, B.1
Kocyk, M.2
Kijewska, M.3
-
40
-
-
84879037098
-
Targeting TGF-beta signaling in cancer
-
Katz LH, Li Y, Chen JS, et al (2013). Targeting TGF-beta signaling in cancer. Expert Opin Ther Targets, 17, 743-60.
-
(2013)
Expert Opin Ther Targets
, vol.17
, pp. 743-760
-
-
Katz, L.H.1
Li, Y.2
Chen, J.S.3
-
41
-
-
0027531528
-
Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death
-
Kulkarni AB, Huh CG, Becker D, et al (1993). Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death. Proc Natl Acad Sci U S A, 90, 770-4.
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 770-774
-
-
Kulkarni, A.B.1
Huh, C.G.2
Becker, D.3
-
42
-
-
84925536864
-
Cutaneous keratoacanthomas/squamous cell carcinomas associated with neutralization of transforming growth factor β by the monoclonal antibody fresolimumab (GC1008)
-
Lacouture M, Morris J, Lawrence D, et al (2015). Cutaneous keratoacanthomas/squamous cell carcinomas associated with neutralization of transforming growth factor β by the monoclonal antibody fresolimumab (GC1008). Cancer Immunol Immunother, 64, 437-46.
-
(2015)
Cancer Immunol Immunother
, vol.64
, pp. 437-446
-
-
Lacouture, M.1
Morris, J.2
Lawrence, D.3
-
43
-
-
84885012536
-
Nodal regulates energy metabolism in glioma cells by inducing expression of hypoxia-inducible factor 1α
-
Lai J-H, Jan H-J, Liu L-W, et al (2013). Nodal regulates energy metabolism in glioma cells by inducing expression of hypoxia-inducible factor 1α. Neuro-Oncol, 15, 1330-41.
-
(2013)
Neuro-Oncol
, vol.15
, pp. 1330-1341
-
-
Lai, J.-H.1
Jan, H.-J.2
Liu, L.-W.3
-
44
-
-
77952954910
-
Nodal promotes growth and invasion in human gliomas
-
Lee CC, Jan HJ, Lai JH, et al (2010). Nodal promotes growth and invasion in human gliomas. Oncogene, 29, 3110-23.
-
(2010)
Oncogene
, vol.29
, pp. 3110-3123
-
-
Lee, C.C.1
Jan, H.J.2
Lai, J.H.3
-
45
-
-
0032213319
-
Neuronal differentiation of precursors in the neocortical ventricular zone is triggered by BMP
-
Li W, Cogswell CA, LoTurco JJ (1998). Neuronal differentiation of precursors in the neocortical ventricular zone is triggered by BMP. J Neurosci, 18, 8853-62.
-
(1998)
J Neurosci
, vol.18
, pp. 8853-8862
-
-
Li, W.1
Cogswell, C.A.2
LoTurco, J.J.3
-
46
-
-
84903892195
-
Interleukin-17 facilitates the immune suppressor capacity of high-grade gliomaderived CD4 (+) CD25 (+) Foxp3 (+) T cells via releasing transforming growth factor beta
-
Liang H, Yi L, Wang X, et al (2014). Interleukin-17 facilitates the immune suppressor capacity of high-grade gliomaderived CD4 (+) CD25 (+) Foxp3 (+) T cells via releasing transforming growth factor beta. Scand J Immunol, 80, 144-50.
-
(2014)
Scand J Immunol
, vol.80
, pp. 144-150
-
-
Liang, H.1
Yi, L.2
Wang, X.3
-
47
-
-
0034517812
-
Noggin antagonizes BMP signaling to create a niche for adult neurogenesis
-
Lim DA, Tramontin AD, Trevejo JM, et al (2000). Noggin antagonizes BMP signaling to create a niche for adult neurogenesis. Neuron, 28, 713-26.
-
(2000)
Neuron
, vol.28
, pp. 713-726
-
-
Lim, D.A.1
Tramontin, A.D.2
Trevejo, J.M.3
-
48
-
-
34547122001
-
The 2007 WHO classification of tumours of the central nervous system
-
Louis DN, Ohgaki H, Wiestler OD, et al (2007). The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol, 114. 97-109.
-
(2007)
Acta Neuropathol
, vol.114
, pp. 97-109
-
-
Louis, D.N.1
Ohgaki, H.2
Wiestler, O.D.3
-
49
-
-
45849110280
-
Transforming growth factor-beta (TGF-beta) and brain tumours
-
Luwor RB, Kaye AH, Zhu HJ (2008). Transforming growth factor-beta (TGF-beta) and brain tumours. J Clin Neurosci, 15, 845-55.
-
(2008)
J Clin Neurosci
, vol.15
, pp. 845-855
-
-
Luwor, R.B.1
Kaye, A.H.2
Zhu, H.J.3
-
50
-
-
58549106104
-
Caveolin-1 regulates glioblastoma aggressiveness through the control of alpha(5) beta(1) integrin expression and modulates glioblastoma responsiveness to SJ749, an alpha(5)beta(1) integrin antagonist
-
Martin S, Cosset EC, Terrand J, et al (2009). Caveolin-1 regulates glioblastoma aggressiveness through the control of alpha(5) beta(1) integrin expression and modulates glioblastoma responsiveness to SJ749, an alpha(5)beta(1) integrin antagonist. Biochim Biophys Acta, 1793, 354-67.
-
(2009)
Biochim Biophys Acta
, vol.1793
, pp. 354-367
-
-
Martin, S.1
Cosset, E.C.2
Terrand, J.3
-
51
-
-
84866742560
-
TGFbeta signalling in context
-
Massague J (2012). TGFbeta signalling in context. Nat Rev Mol Cell Biol, 13, 616-30.
-
(2012)
Nat Rev Mol Cell Biol
, vol.13
, pp. 616-630
-
-
Massague, J.1
-
52
-
-
0026740495
-
TGF-beta receptors
-
Massague J, Andres J, Attisano L, et al (1992). TGF-beta receptors. Mol Reprod Dev, 32, 99-104.
-
(1992)
Mol Reprod Dev
, vol.32
, pp. 99-104
-
-
Massague, J.1
Andres, J.2
Attisano, L.3
-
53
-
-
84936845832
-
Toward an effective strategy in glioblastoma treatment. Part I: resistance mechanisms and strategies to overcome resistance of glioblastoma to temozolomide
-
Messaoudi K, Clavreul A, Lagarce F (2015). Toward an effective strategy in glioblastoma treatment. Part I: resistance mechanisms and strategies to overcome resistance of glioblastoma to temozolomide. Drug Discovery Today.
-
(2015)
Drug Discovery Today
-
-
Messaoudi, K.1
Clavreul, A.2
Lagarce, F.3
-
54
-
-
64249086909
-
Radiation sensitization of glioblastoma by cilengitide has unanticipated schedule-dependency
-
Mikkelsen T, Brodie C, Finniss S, et al (2009). Radiation sensitization of glioblastoma by cilengitide has unanticipated schedule-dependency. Int J Cancer, 124, 2719-27.
-
(2009)
Int J Cancer
, vol.124
, pp. 2719-2727
-
-
Mikkelsen, T.1
Brodie, C.2
Finniss, S.3
-
55
-
-
0034016101
-
Positive and negative regulation of TGFbeta signaling
-
Miyazono K (2000). Positive and negative regulation of TGFbeta signaling. J Cell Sci, 113, 1101-9.
-
(2000)
J Cell Sci
, vol.113
, pp. 1101-1109
-
-
Miyazono, K.1
-
56
-
-
84897566294
-
Phase i study of gc1008 (fresolimumab): a human anti-transforming growth factor-beta (tgfβ) monoclonal antibody in patients with advanced malignant melanoma or renal cell carcinoma
-
Morris JC, Tan AR, Olencki TE, et al (2014). Phase i study of gc1008 (fresolimumab): a human anti-transforming growth factor-beta (tgfβ) monoclonal antibody in patients with advanced malignant melanoma or renal cell carcinoma. PLoS ONE, 9, 90353.
-
(2014)
PLoS ONE
, vol.9
-
-
Morris, J.C.1
Tan, A.R.2
Olencki, T.E.3
-
57
-
-
84886302501
-
Advances and challenges in the treatment of glioblastoma: a clinician's perspective
-
Mrugala MM (2013). Advances and challenges in the treatment of glioblastoma: a clinician's perspective. Discov Med, 15, 221-30.
-
(2013)
Discov Med
, vol.15
, pp. 221-230
-
-
Mrugala, M.M.1
-
59
-
-
80053187240
-
Aberrant signaling pathways in glioma
-
Nakada M, Kita D, Watanabe T, et al (2011). Aberrant signaling pathways in glioma. Cancers (Basel), 3, 3242-78.
-
(2011)
Cancers (Basel)
, vol.3
, pp. 3242-3278
-
-
Nakada, M.1
Kita, D.2
Watanabe, T.3
-
60
-
-
0028282875
-
Production of matrix metalloproteinases and tissue inhibitor of metalloproteinases-1 by human brain tumors
-
Nakagawa T, Kubota T, Kabuto M, et al (1994). Production of matrix metalloproteinases and tissue inhibitor of metalloproteinases-1 by human brain tumors. J Neurosurg, 81, 69-77.
-
(1994)
J Neurosurg
, vol.81
, pp. 69-77
-
-
Nakagawa, T.1
Kubota, T.2
Kabuto, M.3
-
61
-
-
70449711757
-
Genetic alterations and signaling pathways in the evolution of gliomas
-
Ohgaki H, Kleihues P (2009). Genetic alterations and signaling pathways in the evolution of gliomas. Cancer Sci, 100, 2235-41.
-
(2009)
Cancer Sci
, vol.100
, pp. 2235-2241
-
-
Ohgaki, H.1
Kleihues, P.2
-
62
-
-
0033619255
-
Silencing of TGF-beta signalling by the pseudoreceptor BAMBI
-
Onichtchouk D, Chen YG, Dosch R, et al (1999). Silencing of TGF-beta signalling by the pseudoreceptor BAMBI. Nature, 401, 480-5.
-
(1999)
Nature
, vol.401
, pp. 480-485
-
-
Onichtchouk, D.1
Chen, Y.G.2
Dosch, R.3
-
63
-
-
84902489371
-
The epidemiology of glioma in adults: a "state of the science" review
-
Ostrom QT, Bauchet L, Davis FG, et al (2014). The epidemiology of glioma in adults: a "state of the science" review. Neuro Oncol, 16, 896-913.
-
(2014)
Neuro Oncol
, vol.16
, pp. 896-913
-
-
Ostrom, Q.T.1
Bauchet, L.2
Davis, F.G.3
-
64
-
-
84929620816
-
CBTRUS statistical report: primary brain and central nervous system tumors diagnosed in the United States in 2007-2011
-
Ostrom QT, Gittleman H, Liao P, et al (2014). CBTRUS statistical report: primary brain and central nervous system tumors diagnosed in the United States in 2007-2011. Neuro-Oncol, 16, 1-63.
-
(2014)
Neuro-Oncol
, vol.16
, pp. 1-63
-
-
Ostrom, Q.T.1
Gittleman, H.2
Liao, P.3
-
65
-
-
33646345885
-
Increased expression of TGF-beta1 reduces tumor growth of human U-87 Glioblastoma Cells in vivo
-
Pan JJ, Chang WJ, Barone TA, et al (2006). Increased expression of TGF-beta1 reduces tumor growth of human U-87 Glioblastoma Cells in vivo. Cancer Immunology, Immunotherapy, 55, 918-27.
-
(2006)
Cancer Immunology, Immunotherapy
, vol.55
, pp. 918-927
-
-
Pan, J.J.1
Chang, W.J.2
Barone, T.A.3
-
66
-
-
56649117546
-
Glioblastomasecreted factors induce IGFBP7 and angiogenesis by modulating Smad-2-dependent TGF-[beta] signaling
-
Pen A, Moreno MJ, Durocher Y, et al (2008). Glioblastomasecreted factors induce IGFBP7 and angiogenesis by modulating Smad-2-dependent TGF-[beta] signaling. Oncogene, 27, 6834-44.
-
(2008)
Oncogene
, vol.27
, pp. 6834-6844
-
-
Pen, A.1
Moreno, M.J.2
Durocher, Y.3
-
67
-
-
63249123273
-
TGFbeta increases glioma-initiating cell self-renewal through the induction of LIF in human glioblastoma
-
Penuelas S, Anido J, Prieto-Sanchez RM, et al (2009). TGFbeta increases glioma-initiating cell self-renewal through the induction of LIF in human glioblastoma. Cancer Cell, 15, 315-27.
-
(2009)
Cancer Cell
, vol.15
, pp. 315-327
-
-
Penuelas, S.1
Anido, J.2
Prieto-Sanchez, R.M.3
-
68
-
-
84870481111
-
BMP2 sensitizes glioblastoma stem-like cells to Temozolomide by affecting HIF-1α stability and MGMT expression
-
Persano L, Pistollato F, Rampazzo E, et al (2012). BMP2 sensitizes glioblastoma stem-like cells to Temozolomide by affecting HIF-1α stability and MGMT expression. Cell Death Disease, 3, 412.
-
(2012)
Cell Death Disease
, vol.3
, pp. 412
-
-
Persano, L.1
Pistollato, F.2
Rampazzo, E.3
-
69
-
-
36049008358
-
Bone morphogenetic proteins regulate tumorigenicity in human glioblastoma stem cells
-
Piccirillo SG, Vescovi AL (2006). Bone morphogenetic proteins regulate tumorigenicity in human glioblastoma stem cells. Ernst Schering Found Symp Proc, 59-81.
-
(2006)
Ernst Schering Found Symp Proc
, pp. 59-81
-
-
Piccirillo, S.G.1
Vescovi, A.L.2
-
70
-
-
0034673243
-
Transforming growth factors beta(1) (TGF-beta(1)) and TGF-beta(2) promote glioma cell migration via Up-regulation of alpha(V) beta(3) integrin expression
-
Platten M, Wick W, Wild-Bode C, et al (2000). Transforming growth factors beta(1) (TGF-beta(1)) and TGF-beta(2) promote glioma cell migration via Up-regulation of alpha(V) beta(3) integrin expression. Biochem Biophys Res Commun, 268, 607-11.
-
(2000)
Biochem Biophys Res Commun
, vol.268
, pp. 607-611
-
-
Platten, M.1
Wick, W.2
Wild-Bode, C.3
-
71
-
-
79960790320
-
IL-10 and TGF-β2 are overexpressed in tumor spheres cultured from human gliomas
-
Qiu B, Zhang D, Wang C, et al (2011). IL-10 and TGF-β2 are overexpressed in tumor spheres cultured from human gliomas. Molecular Biology Reports, 38, 3585-91.
-
(2011)
Molecular Biology Reports
, vol.38
, pp. 3585-3591
-
-
Qiu, B.1
Zhang, D.2
Wang, C.3
-
72
-
-
84873718730
-
Nodal signalling in embryogenesis and tumourigenesis
-
Quail DF, Siegers GM, Jewer M, et al (2013). Nodal signalling in embryogenesis and tumourigenesis. Int J Biochem Cell Biol, 45, 885-98.
-
(2013)
Int J Biochem Cell Biol
, vol.45
, pp. 885-898
-
-
Quail, D.F.1
Siegers, G.M.2
Jewer, M.3
-
73
-
-
0027215066
-
Elevated levels of M(r) 92 000 type IV collagenase in human brain tumors
-
Rao JS, Steck PA, Mohanam S, et al (1993). Elevated levels of M(r) 92,000 type IV collagenase in human brain tumors. Cancer Res, 53, 2208-11.
-
(1993)
Cancer Res
, vol.53
, pp. 2208-2211
-
-
Rao, J.S.1
Steck, P.A.2
Mohanam, S.3
-
74
-
-
57149108506
-
Randomized phase II study of cilengitide, an integrin-targeting arginineglycine-aspartic acid peptide, in recurrent glioblastomamultiforme
-
Reardon DA, Fink KL, Mikkelsen T, et al (2008). Randomized phase II study of cilengitide, an integrin-targeting arginineglycine-aspartic acid peptide, in recurrent glioblastomamultiforme. J Clin Oncol, 26, 5610-7.
-
(2008)
J Clin Oncol
, vol.26
, pp. 5610-5617
-
-
Reardon, D.A.1
Fink, K.L.2
Mikkelsen, T.3
-
75
-
-
84894963068
-
Implantable controlled release devices for BMP-7 delivery and suppression of glioblastoma initiating cells
-
Reguera-Nuñez E, Roca C, Hardy E, et al (2014). Implantable controlled release devices for BMP-7 delivery and suppression of glioblastoma initiating cells. Biomaterials, 35, 2859-67.
-
(2014)
Biomaterials
, vol.35
, pp. 2859-2867
-
-
Reguera-Nuñez, E.1
Roca, C.2
Hardy, E.3
-
76
-
-
0033521118
-
Transforming growth factor-beta-mediated p15(INK4B) induction and growth inhibition in astrocytes is SMAD3-dependent and a pathway prominently altered in human glioma cell lines
-
Rich JN, Zhang M, Datto MB, et al (1999). Transforming growth factor-beta-mediated p15(INK4B) induction and growth inhibition in astrocytes is SMAD3-dependent and a pathway prominently altered in human glioma cell lines. J Biol Chem, 274, 35053-8.
-
(1999)
J Biol Chem
, vol.274
, pp. 35053-35058
-
-
Rich, J.N.1
Zhang, M.2
Datto, M.B.3
-
77
-
-
14844302670
-
Latent transforming growth factor-β (TGF-β) binding proteins: orchestrators of TGF-β availability
-
Rifkin DB (2005). Latent transforming growth factor-β (TGF-β) binding proteins: orchestrators of TGF-β availability. J Biol Chem, 280, 7409-12.
-
(2005)
J Biol Chem
, vol.280
, pp. 7409-7412
-
-
Rifkin, D.B.1
-
78
-
-
84907486989
-
Active CREB1 promotes a malignant TGFbeta2 autocrine loop in glioblastoma
-
Rodon L, Gonzalez-Junca A, Inda Mdel M, et al (2014). Active CREB1 promotes a malignant TGFbeta2 autocrine loop in glioblastoma. Cancer Discov, 4, 1230-41.
-
(2014)
Cancer Discov
, vol.4
, pp. 1230-1241
-
-
Rodon, L.1
Gonzalez-Junca, A.2
Inda Mdel, M.3
-
79
-
-
77955100047
-
GDF-15 contributes to proliferation and immune escape of malignant gliomas
-
Roth P, Junker M, Tritschler I, et al (2010). GDF-15 contributes to proliferation and immune escape of malignant gliomas. Clin Cancer Res, 16, 3851-9.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 3851-3859
-
-
Roth, P.1
Junker, M.2
Tritschler, I.3
-
80
-
-
84874318559
-
Integrin control of the transforming growth factor-β pathway in glioblastoma
-
Roth P, Silginer M, Goodman SL, et al (2013). Integrin control of the transforming growth factor-β pathway in glioblastoma. Brain, 136, 564-76.
-
(2013)
Brain
, vol.136
, pp. 564-576
-
-
Roth, P.1
Silginer, M.2
Goodman, S.L.3
-
81
-
-
0035914297
-
Synergistic cooperation between hypoxia and transforming growth factor-beta pathways on human vascular endothelial growth factor gene expression
-
Sanchez-Elsner T, Botella LM, Velasco B, et al (2001). Synergistic cooperation between hypoxia and transforming growth factor-beta pathways on human vascular endothelial growth factor gene expression. J Biol Chem, 276, 38527-35.
-
(2001)
J Biol Chem
, vol.276
, pp. 38527-38535
-
-
Sanchez-Elsner, T.1
Botella, L.M.2
Velasco, B.3
-
82
-
-
84867578091
-
EMTactivating transcription factors in cancer: beyond EMT and tumor invasiveness
-
Sánchez-Tilló E, Liu Y, de Barrios O, et al (2012). EMTactivating transcription factors in cancer: beyond EMT and tumor invasiveness. Cellular Molecular Life Sciences, 69, 3429-56.
-
(2012)
Cellular Molecular Life Sciences
, vol.69
, pp. 3429-3456
-
-
Sánchez-Tilló, E.1
Liu, Y.2
de Barrios, O.3
-
83
-
-
79961139550
-
TGF-beta/TGF-beta receptor system and its role in physiological and pathological conditions
-
Santibanez JF, Quintanilla M, Bernabeu C (2011). TGF-beta/TGF-beta receptor system and its role in physiological and pathological conditions. Clin Sci (Lond), 121, 233-51.
-
(2011)
Clin Sci (Lond)
, vol.121
, pp. 233-251
-
-
Santibanez, J.F.1
Quintanilla, M.2
Bernabeu, C.3
-
84
-
-
84888380939
-
Snail depletes the tumorigenic potential of glioblastoma
-
Savary K, Caglayan D, Caja L, et al (2013). Snail depletes the tumorigenic potential of glioblastoma. Oncogene, 32, 5409-20.
-
(2013)
Oncogene
, vol.32
, pp. 5409-5420
-
-
Savary, K.1
Caglayan, D.2
Caja, L.3
-
85
-
-
84875258658
-
Integrin α5β1, the fibronectin receptor, as a pertinent therapeutic target in solid tumors
-
Schaffner F, Ray AM, Dontenwill M (2013). Integrin α5β1, the fibronectin receptor, as a pertinent therapeutic target in solid tumors. Cancers, 5, 27-47.
-
(2013)
Cancers
, vol.5
, pp. 27-47
-
-
Schaffner, F.1
Ray, A.M.2
Dontenwill, M.3
-
86
-
-
84866324123
-
Cancer stem cells and epithelialmesenchymal transition: concepts and molecular links
-
Scheel C, Weinberg RA (2012). Cancer stem cells and epithelialmesenchymal transition: concepts and molecular links. Semin Cancer Biol, 22, 396-403.
-
(2012)
Semin Cancer Biol
, vol.22
, pp. 396-403
-
-
Scheel, C.1
Weinberg, R.A.2
-
87
-
-
1642332084
-
Integration of smad and forkhead pathways in the control of neuroepithelial and glioblastoma cell proliferation
-
Seoane J, Le HV, Shen L, et al (2004). Integration of smad and forkhead pathways in the control of neuroepithelial and glioblastoma cell proliferation. Cell, 17, 211-23.
-
(2004)
Cell
, vol.17
, pp. 211-223
-
-
Seoane, J.1
Le, H.V.2
Shen, L.3
-
88
-
-
84906791490
-
Tumor suppressor NDRG2 tips the balance of oncogenic TGF-[beta] via EMT inhibition in colorectal cancer
-
Shen L, Qu X, Ma Y, et al (2014). Tumor suppressor NDRG2 tips the balance of oncogenic TGF-[beta] via EMT inhibition in colorectal cancer. Oncogenesis, 3, 86.
-
(2014)
Oncogenesis
, vol.3
, pp. 86
-
-
Shen, L.1
Qu, X.2
Ma, Y.3
-
89
-
-
70350712285
-
Elevated levels of MIC-1/GDF15 in the cerebrospinal fluid of patients are associated with glioblastoma and worse outcome
-
Shnaper S, Desbaillets I, Brown DA, et al (2009). Elevated levels of MIC-1/GDF15 in the cerebrospinal fluid of patients are associated with glioblastoma and worse outcome. Int J Cancer, 125, 2624-30.
-
(2009)
Int J Cancer
, vol.125
, pp. 2624-2630
-
-
Shnaper, S.1
Desbaillets, I.2
Brown, D.A.3
-
90
-
-
0026799402
-
Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease
-
Shull MM, Ormsby I, Kier AB, et al (1992). Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease. Nature, 359, 693-9.
-
(1992)
Nature
, vol.359
, pp. 693-699
-
-
Shull, M.M.1
Ormsby, I.2
Kier, A.B.3
-
91
-
-
0242499448
-
Cytostatic and apoptotic actions of TGF-beta in homeostasis and cancer
-
Siegel PM, Massague J (2003). Cytostatic and apoptotic actions of TGF-beta in homeostasis and cancer. Nat Rev Cancer, 3, 807-21.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 807-821
-
-
Siegel, P.M.1
Massague, J.2
-
92
-
-
84906898058
-
Integrin inhibition promotes atypical anoikis in glioma cells
-
Silginer M, Weller M, Ziegler U, et al (2014). Integrin inhibition promotes atypical anoikis in glioma cells. Cell Death Disease, 5, 1012.
-
(2014)
Cell Death Disease
, vol.5
, pp. 1012
-
-
Silginer, M.1
Weller, M.2
Ziegler, U.3
-
93
-
-
9244241576
-
Identification of human brain tumour initiating cells
-
Singh SK, Hawkins C, Clarke ID, et al (2004). Identification of human brain tumour initiating cells. Nature, 432, 396-401.
-
(2004)
Nature
, vol.432
, pp. 396-401
-
-
Singh, S.K.1
Hawkins, C.2
Clarke, I.D.3
-
94
-
-
84874598318
-
Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics
-
Sottoriva A, Spiteri I, Piccirillo SG, et al (2013). Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics. Proc Natl Acad Sci U S A, 110, 4009-14.
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, pp. 4009-4014
-
-
Sottoriva, A.1
Spiteri, I.2
Piccirillo, S.G.3
-
95
-
-
84908563697
-
Cilengitide combined with standard treatment for patients with newly diagnosed glioblastoma with methylated MGMT promoter (CENTRIC EORTC 26071-22072 study): a multicentre, randomised, open-label, phase 3 trial
-
Stupp R, Hegi ME, Gorlia T, et al (2014). Cilengitide combined with standard treatment for patients with newly diagnosed glioblastoma with methylated MGMT promoter (CENTRIC EORTC 26071-22072 study): a multicentre, randomised, open-label, phase 3 trial. Lancet Oncol, 15, 1100-8.
-
(2014)
Lancet Oncol
, vol.15
, pp. 1100-1108
-
-
Stupp, R.1
Hegi, M.E.2
Gorlia, T.3
-
96
-
-
84920187771
-
Lefty inhibits glioma growth by suppressing nodal-activated smad and ERK1/2 pathways
-
Sun G, Shi L, Li M, et al (2014). Lefty inhibits glioma growth by suppressing nodal-activated smad and ERK1/2 pathways. J Neurol Sci, 347, 137-42.
-
(2014)
J Neurol Sci
, vol.347
, pp. 137-142
-
-
Sun, G.1
Shi, L.2
Li, M.3
-
97
-
-
84893691855
-
TGF-β promotes glioma cell growth via activating nodal expression through smad and ERK1/2 pathways
-
Sun J, Liu S-z, Lin Y, et al (2014). TGF-β promotes glioma cell growth via activating nodal expression through smad and ERK1/2 pathways. Biochem Biophys Res Communicat, 443, 1066-72.
-
(2014)
Biochem Biophys Res Communicat
, vol.443
, pp. 1066-1072
-
-
Sun, J.1
Liu, S-z2
Lin, Y.3
-
98
-
-
35448991324
-
Extracellular control of TGFbeta signalling in vascular development and disease
-
Ten Dijke P, Arthur HM (2007). Extracellular control of TGFbeta signalling in vascular development and disease. Nat Rev Mol Cell Biol, 8, 857-69.
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, pp. 857-869
-
-
Ten Dijke, P.1
Arthur, H.M.2
-
99
-
-
54549108740
-
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
-
The Cancer Genome Atlas Research Network (2008). Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature, 455, 1061-8.
-
(2008)
Nature
, vol.455
, pp. 1061-1068
-
-
-
100
-
-
84896973126
-
TGF-β activation and function in immunity
-
Travis MA, Sheppard D (2014). TGF-β activation and function in immunity. Ann Revi Immunol, 32, 51-82.
-
(2014)
Ann Revi Immunol
, vol.32
, pp. 51-82
-
-
Travis, M.A.1
Sheppard, D.2
-
101
-
-
79957839527
-
Activin signaling as an emerging target for therapeutic interventions
-
Tsuchida K, Nakatani M, Hitachi K, et al (2009). Activin signaling as an emerging target for therapeutic interventions. Cell Communicat Signal, 7, 15.
-
(2009)
Cell Communicat Signal
, vol.7
, pp. 15
-
-
Tsuchida, K.1
Nakatani, M.2
Hitachi, K.3
-
102
-
-
0032428684
-
SARA, a FYVE Domain Protein that Recruits Smad2 to the TGFβ Receptor
-
Tsukazaki T, Chiang TA, Davison AF, et al (1998). SARA, a FYVE Domain Protein that Recruits Smad2 to the TGFβ Receptor. Cell, 95, 779-91.
-
(1998)
Cell
, vol.95
, pp. 779-791
-
-
Tsukazaki, T.1
Chiang, T.A.2
Davison, A.F.3
-
103
-
-
7444226411
-
SD-208, a novel transforming growth factor beta receptor I kinase inhibitor, inhibits growth and invasiveness and enhances immunogenicity of murine and human glioma cells in vitro and in vivo
-
Uhl M, Aulwurm S, Wischhusen J, et al (2004). SD-208, a novel transforming growth factor beta receptor I kinase inhibitor, inhibits growth and invasiveness and enhances immunogenicity of murine and human glioma cells in vitro and in vivo. Cancer Res, 64, 7954-61.
-
(2004)
Cancer Res
, vol.64
, pp. 7954-7961
-
-
Uhl, M.1
Aulwurm, S.2
Wischhusen, J.3
-
104
-
-
84862770952
-
Adult cerebellar glioblastoma cases have different characteristics from supratentorial glioblastoma
-
Utsuki S, Oka H, Miyajima Y, et al (2012). Adult cerebellar glioblastoma cases have different characteristics from supratentorial glioblastoma. Brain Tumor Pathol, 29, 87-95.
-
(2012)
Brain Tumor Pathol
, vol.29
, pp. 87-95
-
-
Utsuki, S.1
Oka, H.2
Miyajima, Y.3
-
106
-
-
0028984715
-
Transforming growth factor-beta 1 inhibits the proliferation of rat astrocytes induced by serum and growth factors
-
Vergeli M, Mazzanti B, Ballerini C, et al (1995). Transforming growth factor-beta 1 inhibits the proliferation of rat astrocytes induced by serum and growth factors. J Neurosci Res, 40, 127-33.
-
(1995)
J Neurosci Res
, vol.40
, pp. 127-133
-
-
Vergeli, M.1
Mazzanti, B.2
Ballerini, C.3
-
107
-
-
73649123907
-
An integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1 EGFR and NF1
-
Verhaak RGW, Hoadley KA, Purdom E, et al (2010). An integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR and NF1. Cancer cell, 17, 98.
-
(2010)
Cancer cell
, vol.17
, pp. 98
-
-
Verhaak, R.G.W.1
Hoadley, K.A.2
Purdom, E.3
-
108
-
-
84876817355
-
Beyond TGFbeta: roles of other TGFbeta superfamily members in cancer
-
Wakefield LM, Hill CS (2013). Beyond TGFbeta: roles of other TGFbeta superfamily members in cancer. Nat Rev Cancer, 13, 328-41.
-
(2013)
Nat Rev Cancer
, vol.13
, pp. 328-341
-
-
Wakefield, L.M.1
Hill, C.S.2
-
109
-
-
35748966479
-
'Yin-Yang' functions of transforming growth factor-beta and T regulatory cells in immune regulation
-
Wan YY, Flavell RA (2007). 'Yin-Yang' functions of transforming growth factor-beta and T regulatory cells in immune regulation. Immunol Rev, 220, 199-213.
-
(2007)
Immunol Rev
, vol.220
, pp. 199-213
-
-
Wan, Y.Y.1
Flavell, R.A.2
-
111
-
-
0034765067
-
Glioma cell invasion: regulation of metalloproteinase activity by TGF-beta
-
Wick W, Platten M, Weller M (2001). Glioma cell invasion: regulation of metalloproteinase activity by TGF-beta. J Neurooncol, 53, 177-85.
-
(2001)
J Neurooncol
, vol.53
, pp. 177-185
-
-
Wick, W.1
Platten, M.2
Weller, M.3
-
112
-
-
77951967101
-
Roles for growth factors in cancer progression
-
Witsch E, Sela M, Yarden Y (2010). Roles for growth factors in cancer progression. Physiol (Bethesda), 25, 85-101.
-
(2010)
Physiol (Bethesda)
, vol.25
, pp. 85-101
-
-
Witsch, E.1
Sela, M.2
Yarden, Y.3
-
113
-
-
0031884680
-
TGF-beta receptors and signalling mechanisms
-
Wrana JL (1998). TGF-beta receptors and signalling mechanisms. Miner Electrolyte Metab, 24, 120-30.
-
(1998)
Miner Electrolyte Metab
, vol.24
, pp. 120-130
-
-
Wrana, J.L.1
-
115
-
-
84922828531
-
14-3-3ζ Turns TGF-β's function from tumor suppressor to metastasis promoter in breast cancer by contextual changes of smad partners from p53 to Gli2
-
Xu J, Acharya S, Sahin O, et al (2015). 14-3-3ζ Turns TGF-β's function from tumor suppressor to metastasis promoter in breast cancer by contextual changes of smad partners from p53 to Gli2. Cancer Cell, 27, 177-92.
-
(2015)
Cancer Cell
, vol.27
, pp. 177-192
-
-
Xu, J.1
Acharya, S.2
Sahin, O.3
-
116
-
-
0029114319
-
Enhanced expression of transforming growth factor-beta and its type-I and type-II receptors in human glioblastoma
-
Yamada N, Kato M, Yamashita H, et al (1995). Enhanced expression of transforming growth factor-beta and its type-I and type-II receptors in human glioblastoma. Int J Cancer, 62, 386-92.
-
(1995)
Int J Cancer
, vol.62
, pp. 386-392
-
-
Yamada, N.1
Kato, M.2
Yamashita, H.3
-
117
-
-
84900796733
-
Glioma cancer stem cells secrete Gremlin1 to promote their maintenance within the tumor hierarchy
-
Yan K, Wu Q, Yan DH, et al (2014). Glioma cancer stem cells secrete Gremlin1 to promote their maintenance within the tumor hierarchy. Genes Develop, 28, 1085-100.
-
(2014)
Genes Develop
, vol.28
, pp. 1085-1100
-
-
Yan, K.1
Wu, Q.2
Yan, D.H.3
-
118
-
-
0033104503
-
Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T cell responsiveness to TGF-beta
-
Yang X, Letterio JJ, Lechleider RJ, et al (1999). Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T cell responsiveness to TGF-beta. Embo J, 18, 1280-91.
-
(1999)
Embo J
, vol.18
, pp. 1280-1291
-
-
Yang, X.1
Letterio, J.J.2
Lechleider, R.J.3
-
119
-
-
84885184220
-
Embryonic stem cell self-renewal pathways converge on the transcription factor Tfcp2l1
-
Ye S, Li P, Tong C, et al (2013). Embryonic stem cell self-renewal pathways converge on the transcription factor Tfcp2l1. EMBO Journal, 32, 2548-60.
-
(2013)
EMBO Journal
, vol.32
, pp. 2548-2560
-
-
Ye, S.1
Li, P.2
Tong, C.3
-
120
-
-
84862879740
-
Tumor-associated microglia/macrophages enhance the invasion of glioma stem-like cells via TGF-beta1 signaling pathway
-
Ye XZ, Xu SL, Xin YH, et al (2012). Tumor-associated microglia/macrophages enhance the invasion of glioma stem-like cells via TGF-beta1 signaling pathway. J Immunol, 189, 444-53.
-
(2012)
J Immunol
, vol.189
, pp. 444-453
-
-
Ye, X.Z.1
Xu, S.L.2
Xin, Y.H.3
-
121
-
-
14744292280
-
Downregulation of major histocompatibility complex antigens in invading glioma cells: stealth invasion of the brain
-
Zagzag D, Salnikow K, Chiriboga L, et al (2005). Downregulation of major histocompatibility complex antigens in invading glioma cells: stealth invasion of the brain. Lab Invest, 85, 328-41.
-
(2005)
Lab Invest
, vol.85
, pp. 328-341
-
-
Zagzag, D.1
Salnikow, K.2
Chiriboga, L.3
-
122
-
-
77957744562
-
Expression of activin A and follistatin in glioblastoma and their effects on U87 in vitro
-
Zhang DF, Li XG, Su LJ, et al (2010). Expression of activin A and follistatin in glioblastoma and their effects on U87 in vitro. J Int Med Res, 38, 1343-53.
-
(2010)
J Int Med Res
, vol.38
, pp. 1343-1353
-
-
Zhang, D.F.1
Li, X.G.2
Su, L.J.3
-
123
-
-
33745532884
-
Participation of an abnormality in the transforming growth factor-beta signaling pathway in resistance of malignant glioma cells to growth inhibition induced by that factor
-
Zhang L, Sato E, Amagasaki K, et al (2006). Participation of an abnormality in the transforming growth factor-beta signaling pathway in resistance of malignant glioma cells to growth inhibition induced by that factor. J Neurosurg, 105, 119-28.
-
(2006)
J Neurosurg
, vol.105
, pp. 119-128
-
-
Zhang, L.1
Sato, E.2
Amagasaki, K.3
-
124
-
-
84930453187
-
Cell of origin for malignant gliomas and its implication in therapeutic development
-
Zong H, Parada LF, Baker SJ (2015). Cell of origin for malignant gliomas and its implication in therapeutic development. Cold Spring Harb Perspect Biol.
-
(2015)
Cold Spring Harb Perspect Biol
-
-
Zong, H.1
Parada, L.F.2
Baker, S.J.3
|