-
1
-
-
0028180752
-
A primary requirement for nodal in the formation and main- tenance of the primitive streak in the mouse
-
Conlon, F. L., Lyons, K. M., Takaesu, N., Barth, K. S., Kispert, A., Her- rmann, B., and Robertson, E. J. (1994). A primary requirement for nodal in the formation and main- tenance of the primitive streak in the mouse. Development 120, 1919-1928.
-
(1994)
Development
, vol.120
, pp. 1919-1928
-
-
Conlon, F.L.1
Lyons, K.M.2
Takaesu, N.3
Barth, K.S.4
Kispert, A.5
Herrmann, B.6
Robertson, E.J.7
-
2
-
-
0034785348
-
TGF-beta signaling in tumor suppression and cancer pro- gression
-
Derynck,R.,Akhurst,R. J.,and Balmain, A. (2001). TGF-beta signaling in tumor suppression and cancer pro- gression. Nat. Genet. 29, 117-129.
-
(2001)
Nat. Genet.
, vol.29
, pp. 117-129
-
-
Derynck, R.1
Akhurst, R.J.2
Balmain, A.3
-
3
-
-
80052730839
-
Nodal enhances the activity of FoxO3a and its synergistic interaction with Smads to regulate cyclin G2 tran- scription in ovarian cancer cells
-
Fu, G., and Peng, C. (2011). Nodal enhances the activity of FoxO3a and its synergistic interaction with Smads to regulate cyclin G2 tran- scription in ovarian cancer cells. Oncogene 30, 3953-3966.
-
(2011)
Oncogene
, vol.30
, pp. 3953-3966
-
-
Fu, G.1
Peng, C.2
-
4
-
-
33646035242
-
Activin receptor-like kinases: struc- ture, function and clinical implica- tions
-
Graham, H., and Peng, C. (2006). Activin receptor-like kinases: struc- ture, function and clinical implica- tions. Endocr. Metab. Immune. Dis- ord. Drug 6, 45-48.
-
(2006)
Endocr. Metab. Immune. Dis- ord. Drug
, vol.6
, pp. 45-48
-
-
Graham, H.1
Peng, C.2
-
5
-
-
80052742592
-
Inhibition of Nodal sup- presses angiogenesis and growth of human gliomas
-
Hueng, D. Y., Lin, G. J., Huang, S. H., Liu, L. W., Ju, D. T., Chen, Y. W., Sytwu, H. K., Chang, C., Huang, S. M., Yeh, Y. S., Lee, H. M., and Ma, H. I. (2011). Inhibition of Nodal sup- presses angiogenesis and growth of human gliomas. J. Neurooncol. 104, 21-31.
-
(2011)
J. Neurooncol.
, vol.104
, pp. 21-31
-
-
Hueng, D.Y.1
Lin, G.J.2
Huang, S.H.3
Liu, L.W.4
Ju, D.T.5
Chen, Y.W.6
Sytwu, H.K.7
Chang, C.8
Huang, S.M.9
Yeh, Y.S.10
Lee, H.M.11
Ma, H.I.12
-
6
-
-
3142618508
-
Activin receptor-like kinase-7 induces apop- tosis through activation of MAPKs in a Smad3-dependent mechanism in hepatoma cells
-
Kim, B. C., Van Gelder, H., Kim, T. A., Lee, H. J., Baik, K. G., Chun, H. H., Lee, D. A., Choi, K. S., and Kim, S. J. (2004). Activin receptor-like kinase-7 induces apop- tosis through activation of MAPKs in a Smad3-dependent mechanism in hepatoma cells. J. Biol. Chem. 279, 28458-28465.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 28458-28465
-
-
Kim, B.C.1
Van Gelder, H.2
Kim, T.A.3
Lee, H.J.4
Baik, K.G.5
Chun, H.H.6
Lee, D.A.7
Choi, K.S.8
Kim, S.J.9
-
7
-
-
28144440831
-
Smad3 mediates TGF-beta1-induced colla- gen gel contraction by human lung fibroblasts
-
Kobayashi, T., Liu, X., Wen, F. Q., Kohyama, T., Shen, L., Wang, X. Q., Hashimoto, M., Mao, L., Togo, S., Kawasaki, S., Sugiura, H., Kamio, K., and Rennard, S. I. (2006). Smad3 mediates TGF-beta1-induced colla- gen gel contraction by human lung fibroblasts. Biochem. Biophys. Res. Commun. 339, 290-295.
-
(2006)
Biochem. Biophys. Res. Commun.
, vol.339
, pp. 290-295
-
-
Kobayashi, T.1
Liu, X.2
Wen, F.Q.3
Kohyama, T.4
Shen, L.5
Wang, X.Q.6
Hashimoto, M.7
Mao, L.8
Togo, S.9
Kawasaki, S.10
Sugiura, H.11
Kamio, K.12
Rennard, S.I.13
-
8
-
-
79958239867
-
Reac- tivation of embryonic nodal signal- ing is associated with tumor pro- gression and promotes the growth of prostate cancer cells
-
Lawrence, M. G., Margaryan, N. V., Loessner, D., Collins, A., Kerr, K. M., Turner, M., Seftor, E. A., Stephens, C. R.,Lai,J.,Postovit,L. M.,Clements,J. A., and Hendrix, M. J. (2011). Reac- tivation of embryonic nodal signal- ing is associated with tumor pro- gression and promotes the growth of prostate cancer cells. Prostate 71, 1198-1209.
-
(2011)
Prostate
, vol.71
, pp. 1198-1209
-
-
Lawrence, M.G.1
Margaryan, N.V.2
Loessner, D.3
Collins, A.4
Kerr, K.M.5
Turner, M.6
Seftor, E.A.7
Stephens, C.R.8
Lai, J.9
Postovit, L.M.10
Clements, J.A.11
Hendrix, M.J.12
-
9
-
-
77952954910
-
Nodal promotes growth and invasion in human gliomas
-
Lee, C. C., Jan, H. J., Lai, J. H., Ma, H. I., Hueng, D. Y., Lee, Y. C., Cheng, Y. Y., Liu, L. W.,Wei, H. W., and Lee, H. M. (2010). Nodal promotes growth and invasion in human gliomas. Onco- gene 29, 3110-3123.
-
(2010)
Onco-gene
, vol.29
, pp. 3110-3123
-
-
Lee, C.C.1
Jan, H.J.2
Lai, J.H.3
Ma, H.I.4
Hueng, D.Y.5
Lee, Y.C.6
Cheng, Y.Y.7
Liu, L.W.8
Wei, H.W.9
Lee, H.M.10
-
10
-
-
3843110160
-
Nodal and ALK7 inhibit prolifera- tion and induce apoptosis in human trophoblast cells
-
Munir, S., Xu, G., Wu, Y., Yang, B., Lala, P. K., and Peng, C. (2004). Nodal and ALK7 inhibit prolifera- tion and induce apoptosis in human trophoblast cells. J. Biol. Chem. 279, 31277-31286.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 31277-31286
-
-
Munir, S.1
Xu, G.2
Wu, Y.3
Yang, B.4
Lala, P.K.5
Peng, C.6
-
11
-
-
79952751431
-
Nodal signals through activin receptor-like kinase 7 to inhibit trophoblast migration and invasion: implication in the pathogenesis of preeclampsia
-
Nadeem, L., Munir, S., Fu, G., Dunk, C., Baczyk, D., Caniggia, I., Lye, S., and Peng, C. (2011). Nodal signals through activin receptor-like kinase 7 to inhibit trophoblast migration and invasion: implication in the pathogenesis of preeclampsia. Am. J. Pathol. 178, 1177-1189.
-
(2011)
Am. J. Pathol.
, vol.178
, pp. 1177-1189
-
-
Nadeem, L.1
Munir, S.2
Fu, G.3
Dunk, C.4
Baczyk, D.5
Caniggia, I.6
Lye, S.7
Peng, C.8
-
12
-
-
34249845879
-
Transforming growth factor-betareceptortypeI-dependent fibrogenic gene program is medi-ated via activation of Smad1 and ERK1/2 pathways
-
Pannu, J., Nakerakanti, S., Smith, E., Ten Dijke, P., and Trojanowska, M. (2007). Transforming growth factor-betareceptortypeI-dependent fibrogenic gene program is medi- ated via activation of Smad1 and ERK1/2 pathways. J. Biol. Chem. 282, 10405-10413.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 10405-10413
-
-
Pannu, J.1
Nakerakanti, S.2
Smith, E.3
Ten Dijke, P.4
Trojanowska, M.5
-
13
-
-
0032943080
-
Expression of transforming- growth-factor (TGF)-beta receptors and Smad proteins in glioblastoma cell lines with distinct responses to TGF-beta1
-
Piek, E., Westermark, U., Kastemar, M., Heldin, C. H., Van Zoelen, E. J., Nister, M., and Ten Dijke, P. (1999). Expression of transforming- growth-factor (TGF)-beta receptors and Smad proteins in glioblastoma cell lines with distinct responses to TGF-beta1. Int. J. Cancer 80, 756-763.
-
(1999)
Int. J. Cancer
, vol.80
, pp. 756-763
-
-
Piek, E.1
Westermark, U.2
Kastemar, M.3
Heldin, C.H.4
Van Zoelen, E.J.5
Nister, M.6
Ten Dijke, P.7
-
14
-
-
0035425463
-
The orphan receptor ALK7 and the Activin receptor ALK4 mediate sig- naling by Nodal proteins during ver- tebrate development
-
Reissmann, E., Jornvall, H., Blokzijl, A., Andersson, O., Chang, C., Min- chiotti, G., Persico, M. G., Ibanez, C. F., and Brivanlou, A. H. (2001). The orphan receptor ALK7 and the Activin receptor ALK4 mediate sig- naling by Nodal proteins during ver- tebrate development. Genes Dev. 15, 2010-2022.
-
(2001)
Genes Dev
, vol.15
, pp. 2010-2022
-
-
Reissmann, E.1
Jornvall, H.2
Blokzijl, A.3
Andersson, O.4
Chang, C.5
Minchiotti, G.6
Persico, M.G.7
Ibanez, C.F.8
Brivanlou, A.H.9
-
15
-
-
0029846430
-
A novel type I receptor serine-threonine kinase predominantly expressed in the adult central nervous system
-
Ryden, M., Imamura, T., Jornvall, H., Belluardo, N., Neveu, I., Trupp, M., Okadome, T., Ten Dijke, P., and Ibanez, C. F. (1996). A novel type I receptor serine-threonine kinase predominantly expressed in the adult central nervous system. J. Biol. Chem. 271, 30603-30609.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 30603-30609
-
-
Ryden, M.1
Imamura, T.2
Jornvall, H.3
Belluardo, N.4
Neveu, I.5
Trupp, M.6
Okadome, T.7
Ten Dijke, P.8
Ibanez, C.F.9
-
17
-
-
33947656333
-
Nodal signaling: developmental roles and regulation
-
Shen, M. M. (2007). Nodal signaling: developmental roles and regulation. Development 134, 1023-1034.
-
(2007)
Development
, vol.134
, pp. 1023-1034
-
-
Shen, M.M.1
-
18
-
-
63449105639
-
Compact spher- oid formation by ovarian cancer cells is associated with contractile behav-ior and an invasive phenotype
-
Sodek, K. L., Ringuette, M. J., and Brown, T. J. (2009). Compact spher- oid formation by ovarian cancer cells is associated with contractile behav- ior and an invasive phenotype. Int. J. Cancer 124, 2060-2070.
-
(2009)
Int. J. Cancer
, vol.124
, pp. 2060-2070
-
-
Sodek, K.L.1
Ringuette, M.J.2
Brown, T.J.3
-
19
-
-
69949134052
-
Nodal as a biomarker for melanoma progres- sion and a new therapeutic target for clinical intervention
-
Strizzi, L., Postovit, L. M., Margaryan, N. V., Lipavsky, A., Gadiot, J., Blank, C., Seftor, R. E., Seftor, E. A., and Hendrix, M. J. (2009). Nodal as a biomarker for melanoma progres- sion and a new therapeutic target for clinical intervention. Expert Rev. Dermatol. 4, 67-78.
-
(2009)
Expert Rev. Dermatol.
, vol.4
, pp. 67-78
-
-
Strizzi, L.1
Postovit, L.M.2
Margaryan, N.V.3
Lipavsky, A.4
Gadiot, J.5
Blank, C.6
Seftor, R.E.7
Seftor, E.A.8
Hendrix, M.J.9
-
20
-
-
33746846469
-
Embryonic and tumorigenic pathways converge via Nodal signal- ing: role in melanoma aggressive-ness
-
Topczewska, J. M., Postovit, L. M., Mar- garyan, N. V., Sam, A., Hess, A. R., Wheaton, W. W., Nickoloff, B. J., Topczewski, J., and Hendrix, M. J. (2006). Embryonic and tumorigenic pathways converge via Nodal signal- ing: role in melanoma aggressive- ness. Nat. Med. 12, 925-932.
-
(2006)
Nat. Med.
, vol.12
, pp. 925-932
-
-
Topczewska, J.M.1
Postovit, L.M.2
Mar-garyan, N.V.3
Sam, A.4
Hess, A.R.5
Wheaton, W.W.6
Nickoloff, B.J.7
Topczewski, J.8
Hendrix, M.J.9
-
21
-
-
0030174277
-
Molecular cloning of a novel type I receptor serine/threonine kinase for the TGF beta superfamily from rat brain
-
Tsuchida, K., Sawchenko, P. E., Nishikawa, S., and Vale, W. W. (1996). Molecular cloning of a novel type I receptor serine/threonine kinase for the TGF beta superfamily from rat brain. Mol. Cell. Neurosci. 7, 467-478.
-
(1996)
Mol. Cell. Neurosci.
, vol.7
, pp. 467-478
-
-
Tsuchida, K.1
Sawchenko, P.E.2
Nishikawa, S.3
Vale, W.W.4
-
22
-
-
79955837342
-
Expres-sion of nodal and nodal receptors in prostate stem cells and prostate cancer cells: autocrine effects on cell proliferation and migration
-
Vo, B. T., and Khan, S. A. (2011). Expres- sion of nodal and nodal receptors in prostate stem cells and prostate cancer cells: autocrine effects on cell proliferation and migration. Prostate 71, 1084-1096.
-
(2011)
Prostate
, vol.71
, pp. 1084-1096
-
-
Vo, B.T.1
Khan, S.A.2
-
23
-
-
34547422406
-
Nodal signalling and apoptosis
-
Wang, H., and Tsang, B. K. (2007). Nodal signalling and apoptosis. Reproduction 133, 847-853.
-
(2007)
Reproduction
, vol.133
, pp. 847-853
-
-
Wang, H.1
Tsang, B.K.2
-
24
-
-
0347915660
-
Nodal signaling and vertebrate germ layer formation
-
Weng, W., and Stemple, D. L. (2003). Nodal signaling and vertebrate germ layer formation. Birth Defects Res. C Embryo Today 69, 325-332.
-
(2003)
Birth Defects Res. C Embryo Today
, vol.69
, pp. 325-332
-
-
Weng, W.1
Stemple, D.L.2
-
25
-
-
79958198736
-
Glioblastoma-derived spheroid cul- tures as an experimental model for analysis of EGFR anomalies
-
Witusik-Perkowska, M., Rieske, P., Hulas-Bigoszewska, K., Zakrzewska, M., Stawski, R., Kulczycka-Wojdala, D., Bienkowski, M., Stoczynska-Fid- elus, E., Gresner, S. M., Piaskowski, S., Jaskolski, D. J., Papierz, W., Zakrzewski, K., Kolasa, M., Ironside, J. W., and Liberski, P. P. (2011). Glioblastoma-derived spheroid cul- tures as an experimental model for analysis of EGFR anomalies. J. Neu- rooncol. 102, 395-407.
-
(2011)
J. Neu- rooncol.
, vol.102
, pp. 395-407
-
-
Witusik-Perkowska, M.1
Rieske, P.2
Hulas-Bigoszewska, K.3
Zakrzewska, M.4
Stawski, R.5
Kulczycka-Wojdala, D.6
Bienkowski, M.7
Stoczynska-Fidelus, E.8
Gresner, S.M.9
Piaskowski, S.10
Jaskolski, D.J.11
Papierz, W.12
Zakrzewski, K.13
Kolasa, M.14
Ironside, J.W.15
Liberski, P.P.16
-
26
-
-
58149286563
-
Cyclin G2 is degraded through the ubiquitin-proteasome pathway and mediates the antiproliferative effect of activin receptor-like kinase 7
-
Xu, G., Bernaudo, S., Fu, G., Lee, D. Y., Yang, B. B., and Peng, C. (2008). Cyclin G2 is degraded through the ubiquitin-proteasome pathway and mediates the antiproliferative effect of activin receptor-like kinase 7. Mol. Biol. Cell 19, 4968-4979.
-
(2008)
Mol. Biol. Cell
, vol.19
, pp. 4968-4979
-
-
Xu, G.1
Bernaudo, S.2
Fu, G.3
Lee, D.Y.4
Yang, B.B.5
Peng, C.6
-
27
-
-
8744286786
-
Nodal induces apoptosis and inhibits proliferation in human epithelial ovarian cancer cells via activin receptor-like kinase 7
-
Xu, G., Zhong, Y., Munir, S., Yang, B. B., Tsang, B. K., and Peng, C. (2004). Nodal induces apoptosis and inhibits proliferation in human epithelial ovarian cancer cells via activin receptor-like kinase 7. J. Clin. Endocrinol. Metab. 89, 5523-5534.
-
(2004)
J. Clin. Endocrinol. Metab.
, vol.89
, pp. 5523-5534
-
-
Xu, G.1
Zhong, Y.2
Munir, S.3
Yang, B.B.4
Tsang, B.K.5
Peng, C.6
-
28
-
-
33646128737
-
Activin receptor-like kinase 7 induces apop- tosis through up-regulation of Bax and down-regulation of Xiap in nor- mal and malignant ovarian epithe- lial cell lines
-
Xu, G., Zhou, H., Wang, Q., Auersperg, N., and Peng, C. (2006). Activin receptor-like kinase 7 induces apop- tosis through up-regulation of Bax and down-regulation of Xiap in nor- mal and malignant ovarian epithe- lial cell lines. Mol. Cancer Res. 4, 235-246.
-
(2006)
Mol. Cancer Res.
, vol.4
, pp. 235-246
-
-
Xu, G.1
Zhou, H.2
Wang, Q.3
Auersperg, N.4
Peng, C.5
-
29
-
-
79551553893
-
MicroRNA 376c enhances ovarian cancer cell survival by targeting activin receptor-like kinase 7 impli- cations for chemoresistance
-
Ye,G.,Fu,G.,Cui,S.,Zhao,S.,Bernaudo, S., Bai, Y., Ding, Y., Zhang, Y., Yang, B. B., and Peng, C. (2011). MicroRNA 376c enhances ovarian cancer cell survival by targeting activin receptor-like kinase 7: impli- cations for chemoresistance. J. Cell Sci. 124, 359-368.
-
(2011)
J. Cell Sci
, vol.124
, pp. 359-368
-
-
Ye, G.1
Fu, G.2
Cui, S.3
Zhao, S.4
Bernaudo, S.5
Bai, Y.6
Ding, Y.7
Zhang, Y.8
Yang, B.B.9
Peng, C.10
-
30
-
-
43449115089
-
Nodal and lefty signaling regulates the growth of pancreatic cells
-
Zhang, Y. Q., Sterling, L., Stotland, A., Hua, H., Kritzik, M., and Sarvetnick, N. (2008). Nodal and lefty signaling regulates the growth of pancreatic cells. Dev. Dyn. 237, 1255-1267.
-
(2008)
Dev. Dyn.
, vol.237
, pp. 1255-1267
-
-
Zhang, Y.Q.1
Sterling, L.2
Stotland, A.3
Hua, H.4
Kritzik, M.5
Sarvetnick, N.6
-
31
-
-
77953412947
-
Nodal and activin receptor- like kinase 7 induce apoptosis in human breast cancer cell lines: role of caspase 3
-
Zhong, Y., Xu, G., Ye, G., Lee, D., Modica-Amore, J., and Peng, C. (2009). Nodal and activin receptor- like kinase 7 induce apoptosis in human breast cancer cell lines: role of caspase 3. Int. J. Physiol. Patho- physiol. Pharmacol. 1, 83-96.
-
(2009)
Int. J. Physiol. Patho-physiol. Pharmacol
, vol.1
, pp. 83-96
-
-
Zhong, Y.1
Xu, G.2
Ye, G.3
Lee, D.4
Modica-Amore, J.5
Peng, C.6
|