-
1
-
-
48649086682
-
Mechanisms of disease: Temozolomide and glioblastoma - Look to the future
-
M.M. Mrugala, and M.C. Chamberlain Mechanisms of disease: temozolomide and glioblastoma - look to the future Nat. Clin. Pract. Oncol. 5 2008 476 486
-
(2008)
Nat. Clin. Pract. Oncol.
, vol.5
, pp. 476-486
-
-
Mrugala, M.M.1
Chamberlain, M.C.2
-
3
-
-
0035501062
-
TGF-beta signaling in cancer - A double-edged sword
-
R.J. Akhurst, and R. Derynck TGF-beta signaling in cancer - a double-edged sword Trends Cell Biol. 11 2001 S44 51
-
(2001)
Trends Cell Biol.
, vol.11
, pp. 44-51
-
-
Akhurst, R.J.1
Derynck, R.2
-
4
-
-
0035865158
-
Malignant glioma biology: Role for TGF-beta in growth, motility, angiogenesis, and immune escape
-
M. Platten, W. Wick, and M. Weller Malignant glioma biology: role for TGF-beta in growth, motility, angiogenesis, and immune escape Microsc. Res. Technol. 52 2001 401 410
-
(2001)
Microsc. Res. Technol.
, vol.52
, pp. 401-410
-
-
Platten, M.1
Wick, W.2
Weller, M.3
-
5
-
-
47549090432
-
TGFbeta in Cancer
-
J. Massagué TGFbeta in Cancer Cell 134 2008 215 230
-
(2008)
Cell
, vol.134
, pp. 215-230
-
-
Massagué, J.1
-
6
-
-
0037448319
-
Transforming growth factor-beta-inducible gene-h3 (beta(ig)-h3) promotes cell adhesion of human astrocytoma cells in vitro: Implication of alpha6beta4 integrin
-
M.O. Kim, S.J. Yun, I.S. Kim, S. Sohn, and E.H. Lee Transforming growth factor-beta-inducible gene-h3 (beta(ig)-h3) promotes cell adhesion of human astrocytoma cells in vitro: implication of alpha6beta4 integrin Neurosci. Lett. 336 2003 93 96
-
(2003)
Neurosci. Lett.
, vol.336
, pp. 93-96
-
-
Kim, M.O.1
Yun, S.J.2
Kim, I.S.3
Sohn, S.4
Lee, E.H.5
-
7
-
-
5644248080
-
RNA interference targeting transforming growth factor-beta enhances NKG2D-mediated antiglioma immune response, inhibits glioma cell migration and invasiveness, and abrogates tumorigenicity in vivo
-
M.A. Friese, J. Wischhusen, W. Wick, M. Weiler, G. Eisele, A. Steinle, and M. Weller RNA interference targeting transforming growth factor-beta enhances NKG2D-mediated antiglioma immune response, inhibits glioma cell migration and invasiveness, and abrogates tumorigenicity in vivo Cancer Res. 64 2004 7596 7603
-
(2004)
Cancer Res.
, vol.64
, pp. 7596-7603
-
-
Friese, M.A.1
Wischhusen, J.2
Wick, W.3
Weiler, M.4
Eisele, G.5
Steinle, A.6
Weller, M.7
-
9
-
-
33746846469
-
Embryonic and tumorigenic pathways converge via Nodal signaling: Role in melanoma aggressiveness
-
J.M. Topczewska, L.M. Postovit, N.V. Margaryan, A. Sam, A.R. Hess, W.W. Wheaton, B.J. Nickoloff, J. Topczewski, and M.J. Hendrix Embryonic and tumorigenic pathways converge via Nodal signaling: role in melanoma aggressiveness Nat. Med. 12 2006 925 932
-
(2006)
Nat. Med.
, vol.12
, pp. 925-932
-
-
Topczewska, J.M.1
Postovit, L.M.2
Margaryan, N.V.3
Sam, A.4
Hess, A.R.5
Wheaton, W.W.6
Nickoloff, B.J.7
Topczewski, J.8
Hendrix, M.J.9
-
10
-
-
77953120606
-
Expression of TGF-beta signaling factors in invasive breast cancers: Relationships with age at diagnosis and tumor characteristics
-
J.D. Figueroa, K.C. Flanders, M. Garcia-Closas, W.F. Anderson, X.R. Yang, R.K. Matsuno, M.A. Duggan, R.M. Pfeiffer, A. Ooshima, R. Cornelison, G.L. Gierach, L.A. Brinton, J. Lissowska, B. Peplonska, L.M. Wakefield, and M.E. Sherman Expression of TGF-beta signaling factors in invasive breast cancers: relationships with age at diagnosis and tumor characteristics Breast Cancer Res. Treat. 121 2010 727 735
-
(2010)
Breast Cancer Res. Treat.
, vol.121
, pp. 727-735
-
-
Figueroa, J.D.1
Flanders, K.C.2
Garcia-Closas, M.3
Anderson, W.F.4
Yang, X.R.5
Matsuno, R.K.6
Duggan, M.A.7
Pfeiffer, R.M.8
Ooshima, A.9
Cornelison, R.10
Gierach, G.L.11
Brinton, L.A.12
Lissowska, J.13
Peplonska, B.14
Wakefield, L.M.15
Sherman, M.E.16
-
11
-
-
71149083121
-
Expression of nodal signalling components in cycling human endometrium and in endometrial cancer
-
I. Papageorgiou, P.K. Nicholls, F. Wang, M. Lackmann, Y. Makanji, L.A. Salamonsen, D.M. Robertson, and C.A. Harrison Expression of nodal signalling components in cycling human endometrium and in endometrial cancer Reprod. Biol. Endocrinol. 7 2009 122
-
(2009)
Reprod. Biol. Endocrinol.
, vol.7
, pp. 122
-
-
Papageorgiou, I.1
Nicholls, P.K.2
Wang, F.3
Lackmann, M.4
Makanji, Y.5
Salamonsen, L.A.6
Robertson, D.M.7
Harrison, C.A.8
-
12
-
-
79958239867
-
Reactivation of embryonic nodal signaling is associated with tumor progression and promotes the growth of prostate cancer cells
-
M.G. Lawrence, N.V. Margaryan, D. Loessner, A. Collins, K.M. Kerr, M. Turner, E.A. Seftor, C.R. Stephens, J. Lai, L.M. Postovit, J.A. Clements, M.J. Hendrix, and A. BioResource Reactivation of embryonic nodal signaling is associated with tumor progression and promotes the growth of prostate cancer cells Prostate 71 2011 1198 1209
-
(2011)
Prostate
, vol.71
, pp. 1198-1209
-
-
Lawrence, M.G.1
Margaryan, N.V.2
Loessner, D.3
Collins, A.4
Kerr, K.M.5
Turner, M.6
Seftor, E.A.7
Stephens, C.R.8
Lai, J.9
Postovit, L.M.10
Clements, J.A.11
Hendrix, M.J.12
Bioresource, A.13
-
13
-
-
77952954910
-
Nodal promotes growth and invasion in human gliomas
-
C.C. Lee, H.J. Jan, J.H. Lai, H.I. Ma, D.Y. Hueng, Y.C. Lee, Y.Y. Cheng, L.W. Liu, H.W. Wei, and H.M. Lee Nodal promotes growth and invasion in human gliomas Oncogene 29 2010 3110 3123
-
(2010)
Oncogene
, vol.29
, pp. 3110-3123
-
-
Lee, C.C.1
Jan, H.J.2
Lai, J.H.3
Ma, H.I.4
Hueng, D.Y.5
Lee, Y.C.6
Cheng, Y.Y.7
Liu, L.W.8
Wei, H.W.9
Lee, H.M.10
-
14
-
-
79952751431
-
Nodal signals through activin receptor-like kinase 7 to inhibit trophoblast migration and invasion: Implication in the pathogenesis of preeclampsia
-
L. Nadeem, S. Munir, G. Fu, C. Dunk, D. Baczyk, I. Caniggia, S. Lye, and C. Peng Nodal signals through activin receptor-like kinase 7 to inhibit trophoblast migration and invasion: implication in the pathogenesis of preeclampsia Am. J. Pathol. 178 2011 1177 1189
-
(2011)
Am. J. Pathol.
, vol.178
, pp. 1177-1189
-
-
Nadeem, L.1
Munir, S.2
Fu, G.3
Dunk, C.4
Baczyk, D.5
Caniggia, I.6
Lye, S.7
Peng, C.8
-
15
-
-
34249845879
-
Transforming growth factor-beta receptor type I-dependent fibrogenic gene program is mediated via activation of Smad1 and ERK1/2 pathways
-
J. Pannu, S. Nakerakanti, E. Smith, P. ten Dijke, and M. Trojanowska Transforming growth factor-beta receptor type I-dependent fibrogenic gene program is mediated via activation of Smad1 and ERK1/2 pathways J. Biol. Chem. 282 2007 10405 10413
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 10405-10413
-
-
Pannu, J.1
Nakerakanti, S.2
Smith, E.3
Ten Dijke, P.4
Trojanowska, M.5
-
16
-
-
28144440831
-
Smad3 mediates TGF-beta1-induced collagen gel contraction by human lung fibroblasts
-
T. Kobayashi, X. Liu, F.Q. Wen, T. Kohyama, L. Shen, X.Q. Wang, M. Hashimoto, L. Mao, S. Togo, S. Kawasaki, H. Sugiura, K. Kamio, and S.I. Rennard Smad3 mediates TGF-beta1-induced collagen gel contraction by human lung fibroblasts Biochem. Biophys. Res. Commun. 339 2006 290 295
-
(2006)
Biochem. Biophys. Res. Commun.
, vol.339
, pp. 290-295
-
-
Kobayashi, T.1
Liu, X.2
Wen, F.Q.3
Kohyama, T.4
Shen, L.5
Wang, X.Q.6
Hashimoto, M.7
Mao, L.8
Togo, S.9
Kawasaki, S.10
Sugiura, H.11
Kamio, K.12
Rennard, S.I.13
-
17
-
-
0034666174
-
C-Jun inhibits transforming growth factor beta-mediated transcription by repressing Smad3 transcriptional activity
-
S. Dennler, C. Prunier, N. Ferrand, J.M. Gauthier, and A. Atfi C-Jun inhibits transforming growth factor beta-mediated transcription by repressing Smad3 transcriptional activity J. Biol. Chem. 275 2000 28858 28865
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 28858-28865
-
-
Dennler, S.1
Prunier, C.2
Ferrand, N.3
Gauthier, J.M.4
Atfi, A.5
-
18
-
-
78650334835
-
Regulation of the embryonic morphogen Nodal by Notch4 facilitates manifestation of the aggressive melanoma phenotype
-
K.M. Hardy, D.A. Kirschmann, E.A. Seftor, N.V. Margaryan, L.M. Postovit, L. Strizzi, and M.J. Hendrix Regulation of the embryonic morphogen Nodal by Notch4 facilitates manifestation of the aggressive melanoma phenotype Cancer Res. 70 2010 10340 10350
-
(2010)
Cancer Res.
, vol.70
, pp. 10340-10350
-
-
Hardy, K.M.1
Kirschmann, D.A.2
Seftor, E.A.3
Margaryan, N.V.4
Postovit, L.M.5
Strizzi, L.6
Hendrix, M.J.7
-
20
-
-
33644868712
-
Transforming growth factor-beta: A molecular target for the future therapy of glioblastoma
-
W. Wick, U. Naumann, and M. Weller Transforming growth factor-beta: a molecular target for the future therapy of glioblastoma Curr. Pharm. Des. 12 2006 341 349
-
(2006)
Curr. Pharm. Des.
, vol.12
, pp. 341-349
-
-
Wick, W.1
Naumann, U.2
Weller, M.3
-
21
-
-
33846821916
-
High TGFbeta-Smad activity confers poor prognosis in glioma patients and promotes cell proliferation depending on the methylation of the PDGF-B gene
-
A. Bruna, R.S. Darken, F. Rojo, A. Ocaña, S. Peñuelas, A. Arias, R. Paris, A. Tortosa, J. Mora, J. Baselga, and J. Seoane High TGFbeta-Smad activity confers poor prognosis in glioma patients and promotes cell proliferation depending on the methylation of the PDGF-B gene Cancer Cell 11 2007 147 160
-
(2007)
Cancer Cell
, vol.11
, pp. 147-160
-
-
Bruna, A.1
Darken, R.S.2
Rojo, F.3
Ocaña, A.4
Peñuelas, S.5
Arias, A.6
Paris, R.7
Tortosa, A.8
Mora, J.9
Baselga, J.10
Seoane, J.11
-
22
-
-
0344837389
-
Platelet-derived growth factor-B enhances glioma angiogenesis by stimulating vascular endothelial growth factor expression in tumor endothelia and by promoting pericyte recruitment
-
P. Guo, B. Hu, W. Gu, L. Xu, D. Wang, H.J. Huang, W.K. Cavenee, and S.Y. Cheng Platelet-derived growth factor-B enhances glioma angiogenesis by stimulating vascular endothelial growth factor expression in tumor endothelia and by promoting pericyte recruitment Am. J. Pathol. 162 2003 1083 1093
-
(2003)
Am. J. Pathol.
, vol.162
, pp. 1083-1093
-
-
Guo, P.1
Hu, B.2
Gu, W.3
Xu, L.4
Wang, D.5
Huang, H.J.6
Cavenee, W.K.7
Cheng, S.Y.8
-
23
-
-
78650290339
-
CX3CR1/CX3CL1 axis negatively controls glioma cell invasion and is modulated by transforming growth factor-β1
-
G. Sciumè, A. Soriani, M. Piccoli, L. Frati, A. Santoni, and G. Bernardini CX3CR1/CX3CL1 axis negatively controls glioma cell invasion and is modulated by transforming growth factor-β1 Neuro. Oncol. 12 2010 701 710
-
(2010)
Neuro. Oncol.
, vol.12
, pp. 701-710
-
-
Sciumè, G.1
Soriani, A.2
Piccoli, M.3
Frati, L.4
Santoni, A.5
Bernardini, G.6
-
24
-
-
79953045754
-
TGF-β1 promotes motility and invasiveness of glioma cells through activation of ADAM17
-
Y. Lu, F. Jiang, X. Zheng, M. Katakowski, B. Buller, S.S. To, and M. Chopp TGF-β1 promotes motility and invasiveness of glioma cells through activation of ADAM17 Oncol. Rep. 25 2011 1329 1335
-
(2011)
Oncol. Rep.
, vol.25
, pp. 1329-1335
-
-
Lu, Y.1
Jiang, F.2
Zheng, X.3
Katakowski, M.4
Buller, B.5
To, S.S.6
Chopp, M.7
-
25
-
-
80054044019
-
Glioblastoma angiogenesis and tumor cell invasiveness are differentially regulated by β8 integrin
-
J.H. Tchaicha, S.B. Reyes, J. Shin, M.G. Hossain, F.F. Lang, and J.H. McCarty Glioblastoma angiogenesis and tumor cell invasiveness are differentially regulated by β8 integrin Cancer Res. 71 2011 6371 6381
-
(2011)
Cancer Res.
, vol.71
, pp. 6371-6381
-
-
Tchaicha, J.H.1
Reyes, S.B.2
Shin, J.3
Hossain, M.G.4
Lang, F.F.5
McCarty, J.H.6
-
26
-
-
69949134052
-
Nodal as a biomarker for melanoma progression and a new therapeutic target for clinical intervention
-
L. Strizzi, L.M. Postovit, N.V. Margaryan, A. Lipavsky, J. Gadiot, C. Blank, R.E. Seftor, E.A. Seftor, and M.J. Hendrix Nodal as a biomarker for melanoma progression and a new therapeutic target for clinical intervention Expert Rev. Dermatol. 4 2009 67 78
-
(2009)
Expert Rev. Dermatol.
, vol.4
, pp. 67-78
-
-
Strizzi, L.1
Postovit, L.M.2
Margaryan, N.V.3
Lipavsky, A.4
Gadiot, J.5
Blank, C.6
Seftor, R.E.7
Seftor, E.A.8
Hendrix, M.J.9
-
27
-
-
77949808547
-
The embryonic morphogen, Nodal, is associated with channel-like structures in human malignant melanoma xenografts
-
J.C. McAllister, Q. Zhan, C. Weishaupt, M.Y. Hsu, and G.F. Murphy The embryonic morphogen, Nodal, is associated with channel-like structures in human malignant melanoma xenografts J. Cutaneous Pathol. 37 Suppl. 1 2010 19 25
-
(2010)
J. Cutaneous Pathol.
, vol.37
, Issue.SUPPL. 1
, pp. 19-25
-
-
McAllister, J.C.1
Zhan, Q.2
Weishaupt, C.3
Hsu, M.Y.4
Murphy, G.F.5
-
29
-
-
80052742592
-
Inhibition of Nodal suppresses angiogenesis and growth of human gliomas
-
D.Y. Hueng, G.J. Lin, S.H. Huang, L.W. Liu, D.T. Ju, Y.W. Chen, H.K. Sytwu, C. Chang, S.M. Huang, Y.S. Yeh, H.M. Lee, and H.I. Ma Inhibition of Nodal suppresses angiogenesis and growth of human gliomas J. Neurooncol. 104 2011 21 31
-
(2011)
J. Neurooncol.
, vol.104
, pp. 21-31
-
-
Hueng, D.Y.1
Lin, G.J.2
Huang, S.H.3
Liu, L.W.4
Ju, D.T.5
Chen, Y.W.6
Sytwu, H.K.7
Chang, C.8
Huang, S.M.9
Yeh, Y.S.10
Lee, H.M.11
Ma, H.I.12
-
30
-
-
84874427698
-
Nodal promotes glioblastoma cell growth
-
T. De Silva, G. Ye, Y.Y. Liang, G. Fu, G. Xu, and C. Peng Nodal promotes glioblastoma cell growth Front Endocrinol. (Lausanne) 3 2012 59
-
(2012)
Front Endocrinol. (Lausanne)
, vol.3
, pp. 59
-
-
De Silva, T.1
Ye, G.2
Liang, Y.Y.3
Fu, G.4
Xu, G.5
Peng, C.6
|