Transcriptional profiling of human glioblastoma vessels indicates a key role of VEGF-A and TGFβ2 in vascular abnormalization

Journal of Pathology

Volumn 228, Issue 3, 2012, Pages 378-390

  Dieterich, Lothar C ^a   Mellberg, Sofie ^a   Langenkamp, Elise ^a   Zhang, Lei ^a   Zieba, Agata ^a   Salomäki, Henriikka ^a,f   Teichert, Martin ^b,c   Huang, Hua ^a   Edqvist, Per Henrik ^a   Kraus, Theo ^d   Augustin, Hellmut G ^b,c   Olofsson, Tommie ^a   Larsson, Erik ^a   Söderberg, Ola ^a   Molema, Grietje ^e   Pontén, Fredrik ^a   Georgii Hemming, Patrik ^a   Alafuzoff, Irina ^a   Dimberg, Anna ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b UNIVERSITY OF HEIDELBERG   (Germany)

^c GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^d UNIVERSITY OF MUNICH   (Germany)

^e UNIVERSITY OF GRONINGEN   (Netherlands)

^f UNIVERSITY OF TURKU   (Finland)

Author keywords

angiogenesis; brain tumour; growth factor; laser microdissection; microarray; tumour endothelial marker; vasculature

Indexed keywords

ANGIOPOIETIN 2; ENDOTHELIAL CELL SPECIFIC MOLECULE 1 PROTEIN; PROTEIN; PROTEIN CD93; PROTEIN ELTD1; PROTEIN FILIP1L; PROTEIN TENC1; SMAD PROTEIN; TRANSCRIPTOME; TRANSFORMING GROWTH FACTOR BETA2; UNCLASSIFIED DRUG; VASCULOTROPIN A;

ARTICLE; BLOOD VESSEL; DISEASE ASSOCIATION; ENDOTHELIUM CELL; GENE; GENE EXPRESSION; GENE INDUCTION; GLIOBLASTOMA; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; PHENOTYPE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; TISSUE MICROARRAY; TUMOR MICROENVIRONMENT;

ADULT; AGED; BLOOD VESSELS; BRAIN NEOPLASMS; CASE-CONTROL STUDIES; ENDOTHELIUM, VASCULAR; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GLIOBLASTOMA; HUMANS; LASER CAPTURE MICRODISSECTION; MICROARRAY ANALYSIS; MIDDLE AGED; NEOPLASM GRADING; PERICYTES; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA2; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84867571044     PISSN: 00223417     EISSN: 10969896     Source Type: Journal    
DOI: 10.1002/path.4072     Document Type: Article

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