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Volumn 105, Issue 1, 2006, Pages 119-128

Participation of an abnormality in the transforming growth factor-β signaling pathway in resistance of malignant glioma cells to growth inhibition induced by that factor

Author keywords

Malignant glioma; p21; Ski; Smad; SnoN; Transforming growth factor

Indexed keywords

CYCLIN D1; CYCLIN DEPENDENT KINASE 4; PROTEIN P15; PROTEIN P21; PROTEIN SKI; PROTEIN SNON; SMAD2 PROTEIN; SMAD3 PROTEIN; SMAD4 PROTEIN; SMAD7 PROTEIN; TRANSCRIPTION FACTOR; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

EID: 33745532884     PISSN: 00223085     EISSN: 00223085     Source Type: Journal    
DOI: 10.3171/jns.2006.105.1.119     Document Type: Article
Times cited : (30)

References (48)
  • 1
    • 0033521032 scopus 로고    scopus 로고
    • c-Ski acts as a transcriptional co-repressor in transforming growth factor-β signaling through interaction with smads
    • Akiyoshi S, Inoue H, Hanai J, Kusanagi K, Nemoto N, Miyazono K, et al: c-Ski acts as a transcriptional co-repressor in transforming growth factor-β signaling through interaction with smads. J Biol Chem 274:35269-35277, 1999
    • (1999) J Biol Chem , vol.274 , pp. 35269-35277
    • Akiyoshi, S.1    Inoue, H.2    Hanai, J.3    Kusanagi, K.4    Nemoto, N.5    Miyazono, K.6
  • 2
    • 0030818246 scopus 로고    scopus 로고
    • Kips off to Myc: Implications for TGF-β signaling
    • Alexandrow MG, Moses HL: Kips off to Myc: implications for TGF-β signaling. J Cell Biochem 66:427-432, 1997
    • (1997) J Cell Biochem , vol.66 , pp. 427-432
    • Alexandrow, M.G.1    Moses, H.L.2
  • 3
    • 0034104591 scopus 로고    scopus 로고
    • Smads as transcriptional co-modulators
    • Attisano L, Wrana JL: Smads as transcriptional co-modulators. Curr Opin Cell Biol 12:235-243, 2000
    • (2000) Curr Opin Cell Biol , vol.12 , pp. 235-243
    • Attisano, L.1    Wrana, J.L.2
  • 6
    • 0032934979 scopus 로고    scopus 로고
    • Targeted disruption of Smad3 reveals an essential role in transforming growth factor β-mediated signal transduction
    • Datto MB, Frederick JP, Pan L, Borton AJ, Zhuang Y, Wang XF: Targeted disruption of Smad3 reveals an essential role in transforming growth factor β-mediated signal transduction. Mol Cell Biol 19:2495-504, 1999
    • (1999) Mol Cell Biol , vol.19 , pp. 2495-2504
    • Datto, M.B.1    Frederick, J.P.2    Pan, L.3    Borton, A.J.4    Zhuang, Y.5    Wang, X.F.6
  • 7
    • 0029073142 scopus 로고
    • Transforming growth factor β induces the cyclin-dependent kinase inhibitor p21 through a p53-independent mechanism
    • Datto MB, Li Y, Panus JF, Howe DJ, Xiong Y, Wang XF: Transforming growth factor β induces the cyclin-dependent kinase inhibitor p21 through a p53-independent mechanism. Proc Natl Acad Sci U S A 92:5545-5549, 1995
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 5545-5549
    • Datto, M.B.1    Li, Y.2    Panus, J.F.3    Howe, D.J.4    Xiong, Y.5    Wang, X.F.6
  • 8
    • 0028829465 scopus 로고
    • Functional analysis of the transforming growth factor β responsive elements in the WAF1/Cip1/p21 promoter
    • Datto MB, Yu Y, Wang XF: Functional analysis of the transforming growth factor β responsive elements in the WAF1/Cip1/p21 promoter. J Biol Chem 270:28623-28628, 1995
    • (1995) J Biol Chem , vol.270 , pp. 28623-28628
    • Datto, M.B.1    Yu, Y.2    Wang, X.F.3
  • 9
    • 0027374766 scopus 로고
    • TGF-β inhibition of Cdk4 synthesis is linked to cell cycle arrest
    • Ewen ME, Sluss HK, Whitehouse LL, Livingston DM: TGF-β inhibition of Cdk4 synthesis is linked to cell cycle arrest. Cell 74:1009-1020, 1993
    • (1993) Cell , vol.74 , pp. 1009-1020
    • Ewen, M.E.1    Sluss, H.K.2    Whitehouse, L.L.3    Livingston, D.M.4
  • 10
    • 0034596993 scopus 로고    scopus 로고
    • Smad2, Smad3 and Smad4 cooperate with Sp1 to induce p15(Ink4B) transcription in response to TGF-β
    • Feng XH, Lin X, Derynck R: Smad2, Smad3 and Smad4 cooperate with Sp1 to induce p15(Ink4B) transcription in response to TGF-β. EMBO J 19:5178-5193, 2000
    • (2000) EMBO J , vol.19 , pp. 5178-5193
    • Feng, X.H.1    Lin, X.2    Derynck, R.3
  • 11
    • 0342656549 scopus 로고    scopus 로고
    • Adenovirus-mediated overexpression of p15INK4B inhibits human glioma cell growth, induces replicative senescence, and inhibits telomerase activity similarly to p16INK4A
    • Fuxe J, Akusjarvi G, Goike HM, Roos G, Collins VP, Pettersson RF: Adenovirus-mediated overexpression of p15INK4B inhibits human glioma cell growth, induces replicative senescence, and inhibits telomerase activity similarly to p16INK4A. Cell Growth Differ 11:373-384, 2000
    • (2000) Cell Growth Differ , vol.11 , pp. 373-384
    • Fuxe, J.1    Akusjarvi, G.2    Goike, H.M.3    Roos, G.4    Collins, V.P.5    Pettersson, R.F.6
  • 12
    • 1442332673 scopus 로고    scopus 로고
    • Loss of the Smad3 expression increases susceptibility to tumorigenicity in human gastric cancer
    • Han SU, Kim HT, Seong do H, Kim YS, Park YS, Bang YJ, et al: Loss of the Smad3 expression increases susceptibility to tumorigenicity in human gastric cancer. Oncogene 23:1333-1341, 2004
    • (2004) Oncogene , vol.23 , pp. 1333-1341
    • Han, S.U.1    Kim, H.T.2    Seong Do, H.3    Kim, Y.S.4    Park, Y.S.5    Bang, Y.J.6
  • 13
    • 0028168242 scopus 로고
    • p15INK4B is a potential effector of TGF-β-induced cell cycle arrest
    • Hannon GJ, Beach D: p15INK4B is a potential effector of TGF-β-induced cell cycle arrest. Nature 371:257-261, 1994
    • (1994) Nature , vol.371 , pp. 257-261
    • Hannon, G.J.1    Beach, D.2
  • 14
    • 0035842885 scopus 로고    scopus 로고
    • The N domain of Smad7 is essential for specific inhibition of transforming growth factor-β signaling
    • Hanyu A, Ishidou Y, Ebisawa T, Shimanuki T, Imamura T, Miyazono K: The N domain of Smad7 is essential for specific inhibition of transforming growth factor-β signaling. J Cell Biol 155:1017-1027, 2001
    • (2001) J Cell Biol , vol.155 , pp. 1017-1027
    • Hanyu, A.1    Ishidou, Y.2    Ebisawa, T.3    Shimanuki, T.4    Imamura, T.5    Miyazono, K.6
  • 15
    • 0031587828 scopus 로고    scopus 로고
    • The MAD-related protein Smad7 associates with the TGFβ receptor and functions as an antagonist of TGFβ signaling
    • Hayashi H, Abdollah S, Qiu Y, Cai J, Xu YY, Grinnell BW, et al: The MAD-related protein Smad7 associates with the TGFβ receptor and functions as an antagonist of TGFβ signaling. Cell 89:1165-1173, 1997
    • (1997) Cell , vol.89 , pp. 1165-1173
    • Hayashi, H.1    Abdollah, S.2    Qiu, Y.3    Cai, J.4    Xu, Y.Y.5    Grinnell, B.W.6
  • 16
    • 0031438047 scopus 로고    scopus 로고
    • TGF-β signalling from cell membrane to nucleus through SMAD proteins
    • Heldin CH, Miyazono K, ten Dijke P: TGF-β signalling from cell membrane to nucleus through SMAD proteins. Nature 390:465-471, 1997
    • (1997) Nature , vol.390 , pp. 465-471
    • Heldin, C.H.1    Miyazono, K.2    Ten Dijke, P.3
  • 17
    • 0032451414 scopus 로고    scopus 로고
    • Molecular mechanisms of transforming growth factor-β signaling
    • Hu PP, Datto MB, Wang XF: Molecular mechanisms of transforming growth factor-β signaling. Endocr Rev 19:349-363, 1998
    • (1998) Endocr Rev , vol.19 , pp. 349-363
    • Hu, P.P.1    Datto, M.B.2    Wang, X.F.3
  • 19
    • 0031941943 scopus 로고    scopus 로고
    • Resistance to growth inhibition by transforming growth factor-β in malignant glioma cells with functional receptors
    • Isoe S, Naganuma H, Nakano S, Sasaki A, Satoh E, Nagasaka M, et al: Resistance to growth inhibition by transforming growth factor-β in malignant glioma cells with functional receptors. J Neurosurg 88:529-534, 1998
    • (1998) J Neurosurg , vol.88 , pp. 529-534
    • Isoe, S.1    Naganuma, H.2    Nakano, S.3    Sasaki, A.4    Satoh, E.5    Nagasaka, M.6
  • 21
    • 0034426392 scopus 로고    scopus 로고
    • Correlation of thrombospondin-1 and transforming growth factor-β expression with malignancy of glioma
    • Kawataki T, Naganuma H, Sasaki A, Yoshikawa H, Tasaka K, Nukui H: Correlation of thrombospondin-1 and transforming growth factor-β expression with malignancy of glioma. Neuropathology 20:161-169, 2000
    • (2000) Neuropathology , vol.20 , pp. 161-169
    • Kawataki, T.1    Naganuma, H.2    Sasaki, A.3    Yoshikawa, H.4    Tasaka, K.5    Nukui, H.6
  • 22
    • 2342434705 scopus 로고    scopus 로고
    • Prognostic significance of the expression of Smad4 and Smad7 in human gastric carcinomas
    • Kim YH, Lee HS, Lee HJ, Hur K, Kim WH, Bang YJ, et al: Prognostic significance of the expression of Smad4 and Smad7 in human gastric carcinomas. Ann Oncol 15:574-580, 2004
    • (2004) Ann Oncol , vol.15 , pp. 574-580
    • Kim, Y.H.1    Lee, H.S.2    Lee, H.J.3    Hur, K.4    Kim, W.H.5    Bang, Y.J.6
  • 23
    • 0033934907 scopus 로고    scopus 로고
    • Expression of TGF-β isoforms, TGF-β receptors, and SMAD molecules at different stages of human glioma
    • Kjellman C, Olofsson SP, Hansson O, Von Schantz T, Lindvall M, Nilsson I, et al: Expression of TGF-β isoforms, TGF-β receptors, and SMAD molecules at different stages of human glioma. Int J Cancer 89:251-258, 2000
    • (2000) Int J Cancer , vol.89 , pp. 251-258
    • Kjellman, C.1    Olofsson, S.P.2    Hansson, O.3    Von Schantz, T.4    Lindvall, M.5    Nilsson, I.6
  • 24
    • 0033598408 scopus 로고    scopus 로고
    • The TGF-β signaling inhibitor Smad7 enhances tumorigenicity in pancreatic cancer
    • Kleeff J, Ishiwata T, Maruyama H, Friess H, Truong P, Buchler MW, et al: The TGF-β signaling inhibitor Smad7 enhances tumorigenicity in pancreatic cancer. Oncogene 18:5363-5372, 1999
    • (1999) Oncogene , vol.18 , pp. 5363-5372
    • Kleeff, J.1    Ishiwata, T.2    Maruyama, H.3    Friess, H.4    Truong, P.5    Buchler, M.W.6
  • 25
    • 0028877583 scopus 로고
    • Transforming growth factor-β1 inhibits cyclin D1 expression in intestinal epithelial cells
    • Ko TC, Sheng HM, Reisman D, Thompson EA, Beauchamp RD: Transforming growth factor-β1 inhibits cyclin D1 expression in intestinal epithelial cells. Oncogene 10:177-184, 1995
    • (1995) Oncogene , vol.10 , pp. 177-184
    • Ko, T.C.1    Sheng, H.M.2    Reisman, D.3    Thompson, E.A.4    Beauchamp, R.D.5
  • 26
    • 0032885350 scopus 로고    scopus 로고
    • TGF-β-1 up-regulates cyclin D1 expression in COLO-357 cells, whereas suppression of cyclin D1 levels is associated with down-regulation of the type I TGF-β receptor
    • Kornmann M, Tangvoranuntakul P, Korc M: TGF-β-1 up-regulates cyclin D1 expression in COLO-357 cells, whereas suppression of cyclin D1 levels is associated with down-regulation of the type I TGF-β receptor. Int J Cancer 83:247-254, 1999
    • (1999) Int J Cancer , vol.83 , pp. 247-254
    • Kornmann, M.1    Tangvoranuntakul, P.2    Korc, M.3
  • 27
    • 0028898203 scopus 로고
    • Potential role of WAF1/Cip1/p21 as a mediator of TGF-β cytoinhibitory effect
    • Li CY, Suardet L, Little JB: Potential role of WAF1/Cip1/p21 as a mediator of TGF-β cytoinhibitory effect. J Biol Chem 270:4971-4974, 1995
    • (1995) J Biol Chem , vol.270 , pp. 4971-4974
    • Li, C.Y.1    Suardet, L.2    Little, J.B.3
  • 28
    • 0031685620 scopus 로고    scopus 로고
    • TGF-β signal transduction
    • Massague J: TGF-β signal transduction. Annu Rev Biochem 67:753-791, 1998
    • (1998) Annu Rev Biochem , vol.67 , pp. 753-791
    • Massague, J.1
  • 29
    • 1642364453 scopus 로고    scopus 로고
    • Smad3 has a critical role in TGF-β-mediated growth inhibition and apoptosis in colonic epithelial cells
    • Mithani SK, Balch GC, Shiou SR, Whitehead RH, Datta PK, Beauchamp RD: Smad3 has a critical role in TGF-β-mediated growth inhibition and apoptosis in colonic epithelial cells. J Surg Res 117:296-305, 2004
    • (2004) J Surg Res , vol.117 , pp. 296-305
    • Mithani, S.K.1    Balch, G.C.2    Shiou, S.R.3    Whitehead, R.H.4    Datta, P.K.5    Beauchamp, R.D.6
  • 30
    • 0033788062 scopus 로고    scopus 로고
    • TGF-β/SMAD signaling and its involvement in tumor progression
    • Miyazono K: TGF-β/SMAD signaling and its involvement in tumor progression. Biol Pharm Bull 23:1125-1130, 2000
    • (2000) Biol Pharm Bull , vol.23 , pp. 1125-1130
    • Miyazono, K.1
  • 31
    • 0032499789 scopus 로고    scopus 로고
    • Regulation of the human p21/WAF1/Cip1 promoter in hepatic cells by functional interactions between Sp1 and Smad family members
    • Moustakas A, Kardassis D: Regulation of the human p21/WAF1/Cip1 promoter in hepatic cells by functional interactions between Sp1 and Smad family members. Proc Natl Acad Sci U S A 95:6733-6738, 1998
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 6733-6738
    • Moustakas, A.1    Kardassis, D.2
  • 32
    • 0028211446 scopus 로고
    • Improved bioassay for the detection of transforming growth factor-β1 and β2 in malignant gliomas
    • Naganuma H, Sasaki A, Satoh E, Sakihama T, Tasaka K, Nukui H: Improved bioassay for the detection of transforming growth factor-β1 and β2 in malignant gliomas. Neurol Med Chir (Tokyo) 34:143-149, 1994
    • (1994) Neurol Med Chir (Tokyo) , vol.34 , pp. 143-149
    • Naganuma, H.1    Sasaki, A.2    Satoh, E.3    Sakihama, T.4    Tasaka, K.5    Nukui, H.6
  • 33
    • 0030611757 scopus 로고    scopus 로고
    • Identification of Smad7, a TGF β-inducible antagonist of TGF-β signalling
    • Nakao A, Afrakhte M, Moren A, Nakayama T, Christian JL, Heuchel R, et al: Identification of Smad7, a TGF β-inducible antagonist of TGF-β signalling. Nature 389:631-635, 1997
    • (1997) Nature , vol.389 , pp. 631-635
    • Nakao, A.1    Afrakhte, M.2    Moren, A.3    Nakayama, T.4    Christian, J.L.5    Heuchel, R.6
  • 35
    • 0034703083 scopus 로고    scopus 로고
    • Role of Smad proteins and transcription factor Sp1 in p21(Waf1/Cip1) regulation by transforming growth factor-β
    • Pardali K, Kurisaki A, Moren A, ten Dijke P, Kardassis D, Moustakas A: Role of Smad proteins and transcription factor Sp1 in p21(Waf1/Cip1) regulation by transforming growth factor-β. J Biol Chem 275:29244-29256, 2000
    • (2000) J Biol Chem , vol.275 , pp. 29244-29256
    • Pardali, K.1    Kurisaki, A.2    Moren, A.3    Ten Dijke, P.4    Kardassis, D.5    Moustakas, A.6
  • 36
    • 0037092964 scopus 로고    scopus 로고
    • Transforming growth factor β signaling is disabled early in human endometrial carcinogenesis concomitant with loss of growth inhibition
    • Parekh TV, Gama P, Wen X, Demopoulos R, Munger JS, Carcangiu ML, et al: Transforming growth factor β signaling is disabled early in human endometrial carcinogenesis concomitant with loss of growth inhibition. Cancer Res 62:2778-2790, 2002
    • (2002) Cancer Res , vol.62 , pp. 2778-2790
    • Parekh, T.V.1    Gama, P.2    Wen, X.3    Demopoulos, R.4    Munger, J.S.5    Carcangiu, M.L.6
  • 37
    • 1842431049 scopus 로고    scopus 로고
    • Expression of Smad7 in hepatocellular carcinoma and dysplastic nodules: Resistance mechanism to transforming growth factor-β
    • Park YN, Chae KJ, Oh BK, Choi J, Choi KS, Park C: Expression of Smad7 in hepatocellular carcinoma and dysplastic nodules: resistance mechanism to transforming growth factor-β. Hepatogastroenterology 51:396-400, 2004
    • (2004) Hepatogastroenterology , vol.51 , pp. 396-400
    • Park, Y.N.1    Chae, K.J.2    Oh, B.K.3    Choi, J.4    Choi, K.S.5    Park, C.6
  • 38
    • 0027486047 scopus 로고
    • SnoI, a novel alternatively spliced isoform of the ski protooncogene homolog, sno
    • Pearson-White S: SnoI, a novel alternatively spliced isoform of the ski protooncogene homolog, sno. Nucleic Acids Res 21:4632-4638, 1993
    • (1993) Nucleic Acids Res , vol.21 , pp. 4632-4638
    • Pearson-White, S.1
  • 39
    • 0030789981 scopus 로고    scopus 로고
    • Proto-oncogene Sno expression, alternative isoforms and immediate early serum response
    • Pearson-White S, Crittenden R: Proto-oncogene Sno expression, alternative isoforms and immediate early serum response. Nucleic Acids Res 25:2930-2937, 1997
    • (1997) Nucleic Acids Res , vol.25 , pp. 2930-2937
    • Pearson-White, S.1    Crittenden, R.2
  • 40
    • 0032943080 scopus 로고    scopus 로고
    • Expression of transforming-growth-factor (TGF)-β receptors and Smad proteins in glioblastoma cell lines with distinct responses to TGF-β1
    • Piek E, Westermark U, Kastemar M, Heldin CH, van Zoelen EJ, Nister M, et al: Expression of transforming-growth-factor (TGF)-β receptors and Smad proteins in glioblastoma cell lines with distinct responses to TGF-β1. Int J Cancer 80:756-763, 1999
    • (1999) Int J Cancer , vol.80 , pp. 756-763
    • Piek, E.1    Westermark, U.2    Kastemar, M.3    Heldin, C.H.4    Van Zoelen, E.J.5    Nister, M.6
  • 41
    • 0029153609 scopus 로고
    • Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-β
    • Reynisdottir I, Polyak K, Iavarone A, Massague J: Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-β. Genes Dev 9:1831-1845, 1995
    • (1995) Genes Dev , vol.9 , pp. 1831-1845
    • Reynisdottir, I.1    Polyak, K.2    Iavarone, A.3    Massague, J.4
  • 42
    • 0033521118 scopus 로고    scopus 로고
    • Transforming growth factor-β′-mediated p15(INK4B) induction and growth inhibition in astrocytes is SMAD3-dependent and a pathway prominently altered in human glioma cell lines
    • Rich JN, Zhang M, Datto MB, Bigner DD, Wang XF: Transforming growth factor-β′-mediated p15(INK4B) induction and growth inhibition in astrocytes is SMAD3-dependent and a pathway prominently altered in human glioma cell lines. J Biol Chem 274:35053-35058, 1999
    • (1999) J Biol Chem , vol.274 , pp. 35053-35058
    • Rich, J.N.1    Zhang, M.2    Datto, M.B.3    Bigner, D.D.4    Wang, X.F.5
  • 43
    • 0034998617 scopus 로고    scopus 로고
    • Participation of thrombospondin-1 in the activation of latent transforming growth factor-β in malignant glioma cells
    • Sasaki A, Naganuma H, Satoh E, Kawataki T, Amagasaki K, Nukui H: Participation of thrombospondin-1 in the activation of latent transforming growth factor-β in malignant glioma cells. Neurol Med Chir (Tokyo) 41:253-259, 2001
    • (2001) Neurol Med Chir (Tokyo) , vol.41 , pp. 253-259
    • Sasaki, A.1    Naganuma, H.2    Satoh, E.3    Kawataki, T.4    Amagasaki, K.5    Nukui, H.6
  • 44
    • 0033595704 scopus 로고    scopus 로고
    • Negative feedback regulation of TGF-β signaling by the SnoN oncoprotein
    • Stroschein SL, Wang W, Zhou S, Zhou Q, Luo K: Negative feedback regulation of TGF-β signaling by the SnoN oncoprotein. Science 286:771-774, 1999
    • (1999) Science , vol.286 , pp. 771-774
    • Stroschein, S.L.1    Wang, W.2    Zhou, S.3    Zhou, Q.4    Luo, K.5
  • 45
  • 46
    • 0033607240 scopus 로고    scopus 로고
    • SnoN and Ski protooncoproteins are rapidly degraded in response to transforming growth factor β signaling
    • Sun Y, Liu X, Ng-Eaton E, Lodish HF, Weinberg RA: SnoN and Ski protooncoproteins are rapidly degraded in response to transforming growth factor β signaling. Proc Natl Acad Sci U S A 96:12442-12447, 1999
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 12442-12447
    • Sun, Y.1    Liu, X.2    Ng-Eaton, E.3    Lodish, H.F.4    Weinberg, R.A.5
  • 47
    • 0033595799 scopus 로고    scopus 로고
    • A new blocker for the TGF-β pathway
    • Vogel G: A new blocker for the TGF-β pathway. Science 286:665, 1999
    • (1999) Science , vol.286 , pp. 665
    • Vogel, G.1
  • 48


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