메뉴 건너뛰기




Volumn 11, Issue 2, 2007, Pages 147-160

High TGFβ-Smad Activity Confers Poor Prognosis in Glioma Patients and Promotes Cell Proliferation Depending on the Methylation of the PDGF-B Gene

Author keywords

SIGNALING

Indexed keywords

PLATELET DERIVED GROWTH FACTOR B; TRANSCRIPTOME; TRANSFORMING GROWTH FACTOR BETA; SMAD2 PROTEIN; SMAD7 PROTEIN; TRANSFORMING GROWTH FACTOR BETA RECEPTOR;

EID: 33846821916     PISSN: 15356108     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ccr.2006.11.023     Document Type: Article
Times cited : (425)

References (35)
  • 1
    • 30644467227 scopus 로고    scopus 로고
    • Inhibition of TGFβ signaling in cancer therapy
    • Arteaga C.L. Inhibition of TGFβ signaling in cancer therapy. Curr. Opin. Genet. Dev. 16 (2006) 30-37
    • (2006) Curr. Opin. Genet. Dev. , vol.16 , pp. 30-37
    • Arteaga, C.L.1
  • 2
    • 28644447930 scopus 로고    scopus 로고
    • TLR agonists regulate PDGF-B production and cell proliferation through TGF-β/type I IFN crosstalk
    • Chow E.K., O'Connell R.M., Schilling S., Wang X.F., Fu X.Y., and Cheng G. TLR agonists regulate PDGF-B production and cell proliferation through TGF-β/type I IFN crosstalk. EMBO J. 24 (2005) 4071-4081
    • (2005) EMBO J. , vol.24 , pp. 4071-4081
    • Chow, E.K.1    O'Connell, R.M.2    Schilling, S.3    Wang, X.F.4    Fu, X.Y.5    Cheng, G.6
  • 3
    • 0035425048 scopus 로고    scopus 로고
    • PDGF autocrine stimulation dedifferentiates cultured astrocytes and induces oligodendrogliomas and oligoastrocytomas from neural progenitors and astrocytes in vivo
    • Dai C., Celestino J.C., Okada Y., Louis D.N., Fuller G.N., and Holland E.C. PDGF autocrine stimulation dedifferentiates cultured astrocytes and induces oligodendrogliomas and oligoastrocytomas from neural progenitors and astrocytes in vivo. Genes Dev. 15 (2001) 1913-1925
    • (2001) Genes Dev. , vol.15 , pp. 1913-1925
    • Dai, C.1    Celestino, J.C.2    Okada, Y.3    Louis, D.N.4    Fuller, G.N.5    Holland, E.C.6
  • 4
    • 0142104985 scopus 로고    scopus 로고
    • Smad-dependent and Smad-independent pathways in TGF-β family signalling
    • Derynck R., and Zhang Y.E. Smad-dependent and Smad-independent pathways in TGF-β family signalling. Nature 425 (2003) 577-584
    • (2003) Nature , vol.425 , pp. 577-584
    • Derynck, R.1    Zhang, Y.E.2
  • 5
    • 0034785348 scopus 로고    scopus 로고
    • TGF-β signaling in tumor suppression and cancer progression
    • Derynck R., Akhurst R.J., and Balmain A. TGF-β signaling in tumor suppression and cancer progression. Nat. Genet. 29 (2001) 117-129
    • (2001) Nat. Genet. , vol.29 , pp. 117-129
    • Derynck, R.1    Akhurst, R.J.2    Balmain, A.3
  • 6
    • 4344623889 scopus 로고    scopus 로고
    • Imatinib as a paradigm of targeted therapies
    • Druker B.J. Imatinib as a paradigm of targeted therapies. Adv. Cancer Res. 91 (2004) 1-30
    • (2004) Adv. Cancer Res. , vol.91 , pp. 1-30
    • Druker, B.J.1
  • 7
    • 0038724672 scopus 로고    scopus 로고
    • Targeting the TGFβ signaling network in human neoplasia
    • Dumont N., and Arteaga C.L. Targeting the TGFβ signaling network in human neoplasia. Cancer Cell 3 (2003) 531-536
    • (2003) Cancer Cell , vol.3 , pp. 531-536
    • Dumont, N.1    Arteaga, C.L.2
  • 8
    • 2942676788 scopus 로고    scopus 로고
    • The PDGF family: Four gene products form five dimeric isoforms
    • Fredriksson L., Li H., and Eriksson U. The PDGF family: Four gene products form five dimeric isoforms. Cytokine Growth Factor Rev. 15 (2004) 197-204
    • (2004) Cytokine Growth Factor Rev. , vol.15 , pp. 197-204
    • Fredriksson, L.1    Li, H.2    Eriksson, U.3
  • 9
    • 0344837389 scopus 로고    scopus 로고
    • Platelet-derived growth factor-B enhances glioma angiogenesis by stimulating vascular endothelial growth factor expression in tumor endothelia and by promoting pericyte recruitment
    • Guo P., Hu B., Gu W., Xu L., Wang D., Huang H.J., Cavenee W.K., and Cheng S.Y. Platelet-derived growth factor-B enhances glioma angiogenesis by stimulating vascular endothelial growth factor expression in tumor endothelia and by promoting pericyte recruitment. Am. J. Pathol. 162 (2003) 1083-1093
    • (2003) Am. J. Pathol. , vol.162 , pp. 1083-1093
    • Guo, P.1    Hu, B.2    Gu, W.3    Xu, L.4    Wang, D.5    Huang, H.J.6    Cavenee, W.K.7    Cheng, S.Y.8
  • 10
    • 0035256772 scopus 로고    scopus 로고
    • Gliomagenesis: Genetic alterations and mouse models
    • Holland E.C. Gliomagenesis: Genetic alterations and mouse models. Nat. Rev. Genet. 2 (2001) 120-129
    • (2001) Nat. Rev. Genet. , vol.2 , pp. 120-129
    • Holland, E.C.1
  • 11
    • 0031047519 scopus 로고    scopus 로고
    • Transforming growth factor beta as a potential tumor progression factor among hyperdiploid glioblastoma cultures: Evidence for the role of platelet-derived growth factor
    • Jennings M.T., Hart C.E., Commers P.A., Whitlock J.A., Martincic D., Maciunas R.J., Moots P.L., and Shehab T.M. Transforming growth factor beta as a potential tumor progression factor among hyperdiploid glioblastoma cultures: Evidence for the role of platelet-derived growth factor. J. Neurooncol. 31 (1997) 233-254
    • (1997) J. Neurooncol. , vol.31 , pp. 233-254
    • Jennings, M.T.1    Hart, C.E.2    Commers, P.A.3    Whitlock, J.A.4    Martincic, D.5    Maciunas, R.J.6    Moots, P.L.7    Shehab, T.M.8
  • 12
    • 0027295384 scopus 로고
    • Identification and characterization of an essential, activating regulatory element of the human SIS/PDGFB promoter in human megakaryocytes
    • Jin H.M., Brady M.L., and Fahl W.E. Identification and characterization of an essential, activating regulatory element of the human SIS/PDGFB promoter in human megakaryocytes. Proc. Natl. Acad. Sci. USA 90 (1993) 7563-7567
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 7563-7567
    • Jin, H.M.1    Brady, M.L.2    Fahl, W.E.3
  • 13
    • 0034162718 scopus 로고    scopus 로고
    • Interleukin-13 receptor alpha chain: A novel tumor-associated transmembrane protein in primary explants of human malignant gliomas
    • Joshi B.H., Plautz G.E., and Puri R.K. Interleukin-13 receptor alpha chain: A novel tumor-associated transmembrane protein in primary explants of human malignant gliomas. Cancer Res. 60 (2000) 1168-1172
    • (2000) Cancer Res. , vol.60 , pp. 1168-1172
    • Joshi, B.H.1    Plautz, G.E.2    Puri, R.K.3
  • 14
    • 0038369998 scopus 로고    scopus 로고
    • A self-enabling TGFβ response coupled to stress signaling: Smad engages stress response factor ATF3 for Id1 repression in epithelial cells
    • Kang Y., Chen C.R., and Massague J. A self-enabling TGFβ response coupled to stress signaling: Smad engages stress response factor ATF3 for Id1 repression in epithelial cells. Mol. Cell 11 (2003) 915-926
    • (2003) Mol. Cell , vol.11 , pp. 915-926
    • Kang, Y.1    Chen, C.R.2    Massague, J.3
  • 17
    • 33646358694 scopus 로고    scopus 로고
    • Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines
    • Lee J., Kotliarova S., Kotliarov Y., Li A., Su Q., Donin N.M., Pastorino S., Purow B.W., Christopher N., Zhang W., et al. Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines. Cancer Cell 9 (2006) 391-403
    • (2006) Cancer Cell , vol.9 , pp. 391-403
    • Lee, J.1    Kotliarova, S.2    Kotliarov, Y.3    Li, A.4    Su, Q.5    Donin, N.M.6    Pastorino, S.7    Purow, B.W.8    Christopher, N.9    Zhang, W.10
  • 18
    • 1142287597 scopus 로고    scopus 로고
    • Expression of platelet-derived growth factor-BB in liver tissues of patients with chronic hepatitis B
    • Lou S.M., Li Y.M., Wang K.M., Cai W.M., and Weng H.L. Expression of platelet-derived growth factor-BB in liver tissues of patients with chronic hepatitis B. World J. Gastroenterol. 10 (2004) 385-388
    • (2004) World J. Gastroenterol. , vol.10 , pp. 385-388
    • Lou, S.M.1    Li, Y.M.2    Wang, K.M.3    Cai, W.M.4    Weng, H.L.5
  • 20
  • 21
    • 24944497786 scopus 로고    scopus 로고
    • Non-Smad TGF-β signals
    • Moustakas A., and Heldin C.H. Non-Smad TGF-β signals. J. Cell Sci. 118 (2005) 3573-3584
    • (2005) J. Cell Sci. , vol.118 , pp. 3573-3584
    • Moustakas, A.1    Heldin, C.H.2
  • 22
    • 2942670180 scopus 로고    scopus 로고
    • PDGF receptors-mediators of autocrine tumor growth and regulators of tumor vasculature and stroma
    • Ostman A. PDGF receptors-mediators of autocrine tumor growth and regulators of tumor vasculature and stroma. Cytokine Growth Factor Rev. 15 (2004) 275-286
    • (2004) Cytokine Growth Factor Rev. , vol.15 , pp. 275-286
    • Ostman, A.1
  • 23
    • 0032943080 scopus 로고    scopus 로고
    • Expression of transforming-growth-factor (TGF)-beta receptors and Smad proteins in glioblastoma cell lines with distinct responses to TGF-β1
    • Piek E., Westermark U., Kastemar M., Heldin C.H., van Zoelen E.J., Nister M., and Ten Dijke P. Expression of transforming-growth-factor (TGF)-beta receptors and Smad proteins in glioblastoma cell lines with distinct responses to TGF-β1. Int. J. Cancer 80 (1999) 756-763
    • (1999) Int. J. Cancer , vol.80 , pp. 756-763
    • Piek, E.1    Westermark, U.2    Kastemar, M.3    Heldin, C.H.4    van Zoelen, E.J.5    Nister, M.6    Ten Dijke, P.7
  • 24
    • 0042634444 scopus 로고    scopus 로고
    • The role of transforming growth factor-beta in primary brain tumors
    • Rich J.N. The role of transforming growth factor-beta in primary brain tumors. Front. Biosci. 8 (2003) e245-e260
    • (2003) Front. Biosci. , vol.8
    • Rich, J.N.1
  • 25
    • 0033521118 scopus 로고    scopus 로고
    • Transforming growth factor-beta-mediated p15(INK4B) induction and growth inhibition in astrocytes is SMAD3-dependent and a pathway prominently altered in human glioma cell lines
    • Rich J.N., Zhang M., Datto M.B., Bigner D.D., and Wang X.F. Transforming growth factor-beta-mediated p15(INK4B) induction and growth inhibition in astrocytes is SMAD3-dependent and a pathway prominently altered in human glioma cell lines. J. Biol. Chem. 274 (1999) 35053-35058
    • (1999) J. Biol. Chem. , vol.274 , pp. 35053-35058
    • Rich, J.N.1    Zhang, M.2    Datto, M.B.3    Bigner, D.D.4    Wang, X.F.5
  • 27
    • 33750069029 scopus 로고    scopus 로고
    • Escaping from the TGFβ anti-proliferative control
    • Seoane J. Escaping from the TGFβ anti-proliferative control. Carcinogenesis 27 (2006) 2148-2156
    • (2006) Carcinogenesis , vol.27 , pp. 2148-2156
    • Seoane, J.1
  • 28
    • 1642332084 scopus 로고    scopus 로고
    • Integration of Smad and forkhead pathways in the control of neuroepithelial and glioblastoma cell proliferation
    • Seoane J., Le H.V., Shen L., Anderson S.A., and Massague J. Integration of Smad and forkhead pathways in the control of neuroepithelial and glioblastoma cell proliferation. Cell 117 (2004) 211-223
    • (2004) Cell , vol.117 , pp. 211-223
    • Seoane, J.1    Le, H.V.2    Shen, L.3    Anderson, S.A.4    Massague, J.5
  • 29
    • 0242499448 scopus 로고    scopus 로고
    • Cytostatic and apoptotic actions of TGF-β in homeostasis and cancer
    • Siegel P.M., and Massague J. Cytostatic and apoptotic actions of TGF-β in homeostasis and cancer. Nat. Rev. Cancer 3 (2003) 807-821
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 807-821
    • Siegel, P.M.1    Massague, J.2
  • 30
    • 0034595653 scopus 로고    scopus 로고
    • Induction of platelet-derived growth factor B-chain expression by transforming growth factor-beta involves transactivation by Smads
    • Taylor L.M., and Khachigian L.M. Induction of platelet-derived growth factor B-chain expression by transforming growth factor-beta involves transactivation by Smads. J. Biol. Chem. 275 (2000) 16709-16716
    • (2000) J. Biol. Chem. , vol.275 , pp. 16709-16716
    • Taylor, L.M.1    Khachigian, L.M.2
  • 31
    • 0032810847 scopus 로고    scopus 로고
    • Immunohistochemical expression of growth factors in subacute thyroiditis and their effects on thyroid folliculogenesis and angiogenesis in collagen gel matrix culture
    • Toda S., Nishimura T., Yamada S., Koike N., Yonemitsu N., Watanabe K., Matsumura S., Gartner R., and Sugihara H. Immunohistochemical expression of growth factors in subacute thyroiditis and their effects on thyroid folliculogenesis and angiogenesis in collagen gel matrix culture. J. Pathol. 188 (1999) 415-422
    • (1999) J. Pathol. , vol.188 , pp. 415-422
    • Toda, S.1    Nishimura, T.2    Yamada, S.3    Koike, N.4    Yonemitsu, N.5    Watanabe, K.6    Matsumura, S.7    Gartner, R.8    Sugihara, H.9
  • 33
    • 30144433414 scopus 로고    scopus 로고
    • Hypomethylation-linked activation of PAX2 mediates tamoxifen-stimulated endometrial carcinogenesis
    • Wu H., Chen Y., Liang J., Shi B., Wu G., Zhang Y., Wang D., Li R., Yi X., Zhang H., et al. Hypomethylation-linked activation of PAX2 mediates tamoxifen-stimulated endometrial carcinogenesis. Nature 438 (2005) 981-987
    • (2005) Nature , vol.438 , pp. 981-987
    • Wu, H.1    Chen, Y.2    Liang, J.3    Shi, B.4    Wu, G.5    Zhang, Y.6    Wang, D.7    Li, R.8    Yi, X.9    Zhang, H.10
  • 34
    • 10444261212 scopus 로고    scopus 로고
    • Development of TGF-β signalling inhibitors for cancer therapy
    • Yingling J.M., Blanchard K.L., and Sawyer J.S. Development of TGF-β signalling inhibitors for cancer therapy. Nat. Rev. Drug Discov. 3 (2004) 1011-1022
    • (2004) Nat. Rev. Drug Discov. , vol.3 , pp. 1011-1022
    • Yingling, J.M.1    Blanchard, K.L.2    Sawyer, J.S.3
  • 35
    • 0036675901 scopus 로고    scopus 로고
    • The molecular and genetic basis of neurological tumours
    • Zhu Y., and Parada L.F. The molecular and genetic basis of neurological tumours. Nat. Rev. Cancer 2 (2002) 616-626
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 616-626
    • Zhu, Y.1    Parada, L.F.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.