HIF-1-driven skeletal muscle adaptations to chronic hypoxia: Molecular insights into muscle physiology

Cellular and Molecular Life Sciences

Volumn 72, Issue 24, 2015, Pages 4681-4696

  Favier, F B ^a,b   Britto, F A ^a,b   Freyssenet, D G ^c   Bigard, X A ^d   Benoit, H ^e,f  

^a University of Montpellier   (France)

^b UNIV MONTPELLIER   (France)

^c UNIVERSITÉ JEAN MONNET   (France)

^d Rue Saint Dominique 75007 Paris   (France)

^e INSERM   (France)

^f UNIV GRENOBLE ALPES   (France)

Author keywords

Altitude; Atrophy; Hypoxia inducible factor; Metabolism; Mitochondria; Oxidative stress

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 2ALPHA; HYPOXIA INDUCIBLE FACTOR 3ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; OXYGEN; REACTIVE OXYGEN METABOLITE;

ACETYLATION; AEROBIC METABOLISM; ANAEROBIC GLYCOLYSIS; DIMERIZATION; DISEASE SEVERITY; ENERGY METABOLISM; ENZYME ACTIVATION; EXERCISE; FATTY ACID OXIDATION; GLUCOSE METABOLISM; HUMAN; HYDROXYLATION; HYPOXEMIA; LIPID OXIDATION; MITOCHONDRION; MUSCLE MASS; MUSCLE METABOLISM; MUSCULOSKELETAL FUNCTION; NONHUMAN; OXIDATIVE STRESS; OXYGEN DIFFUSION; OXYGEN TENSION; OXYGENATION; PROTEIN CONTENT; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; PROTEIN STABILITY; PROTEIN SYNTHESIS; REVIEW; SKELETAL MUSCLE; ANIMAL; BIOLOGICAL MODEL; CELL HYPOXIA; CYTOLOGY; METABOLISM; MOUSE; PHYSIOLOGICAL STRESS; PHYSIOLOGY; RAT; SIGNAL TRANSDUCTION;

ANIMALS; CELL HYPOXIA; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; METABOLIC NETWORKS AND PATHWAYS; MICE; MITOCHONDRIA; MODELS, BIOLOGICAL; MUSCLE, SKELETAL; OXYGEN; RATS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; STRESS, PHYSIOLOGICAL;

EID: 84947616213     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-015-2025-9     Document Type: Review

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