Hypoxia-inducible factor 1 mediates hypoxia-induced cardiomyocyte lipid accumulation by reducing the DNA binding activity of peroxisome proliferator-activated receptor α/retinoid X receptor

Biochemical and Biophysical Research Communications

Volumn 364, Issue 3, 2007, Pages 567-572

  Belanger, Adam J ^a   Luo, Zhengyu ^a   Vincent, Karen A ^a   Akita, Geoffrey Y ^a   Cheng, Seng H ^a   Gregory, Richard J ^a   Jiang, Canwen ^a  

^a GENZYME CORPORATION   (United States)

Author keywords

HIF 1; Hypoxia; M CPT I; Neural lipid accumulation; PPAR

Indexed keywords

DNA; HYPOXIA INDUCIBLE FACTOR 1; LIPID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; RETINOID X RECEPTOR;

ANIMAL CELL; ARTICLE; CATALYSIS; CONTROLLED STUDY; DNA BINDING; DNA DEGRADATION; FATTY ACID OXIDATION; HEART MITOCHONDRION; HEART MUSCLE ISCHEMIA; LIPID STORAGE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN FUNCTION; PROTEIN SYNTHESIS INHIBITION; RAT;

ANIMALS; ANIMALS, NEWBORN; CELL HYPOXIA; CELLS, CULTURED; DNA; DNA-BINDING PROTEINS; HYPOXIA-INDUCIBLE FACTOR 1; LIPID METABOLISM; MITOCHONDRIA, HEART; MYOCYTES, CARDIAC; PPAR ALPHA; RATS; RETINOID X RECEPTORS;

ADENOVIRIDAE;

EID: 35649023152     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2007.10.062     Document Type: Article

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