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Volumn 24, Issue , 2015, Pages 17-28

DAMPs and neurodegeneration

Author keywords

DAMPs; Inflammasomes; Neurodegeneration; Neuroinflammation; PRRs

Indexed keywords

ADENOSINE TRIPHOSPHATE; ADVANCED GLYCATION END PRODUCT RECEPTOR; ALPHA SYNUCLEIN; BECLIN 1; CRYOPYRIN; HEAT SHOCK PROTEIN; HIGH MOBILITY GROUP B1 PROTEIN; INFLAMMASOME; INTERLEUKIN 1BETA; MITOCHONDRIAL DNA; NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN LIKE RECEPTOR; PROTEIN S100B; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 4; URIC ACID;

EID: 84946830786     PISSN: 15681637     EISSN: 18729649     Source Type: Journal    
DOI: 10.1016/j.arr.2014.11.003     Document Type: Review
Times cited : (55)

References (151)
  • 1
    • 73649130290 scopus 로고    scopus 로고
    • Heat shock proteins in neurodegenerative diseases: pathogenic roles and therapeutic implications
    • Adachi H., Katsuno M., Waza M., Minamiyama M., Tanaka F., Sobue G. Heat shock proteins in neurodegenerative diseases: pathogenic roles and therapeutic implications. Int. J. Hyperther 2009, 25:647-654. (the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group).
    • (2009) Int. J. Hyperther , vol.25 , pp. 647-654
    • Adachi, H.1    Katsuno, M.2    Waza, M.3    Minamiyama, M.4    Tanaka, F.5    Sobue, G.6
  • 2
    • 36048943239 scopus 로고    scopus 로고
    • Gout and risk of Parkinson disease: a prospective study
    • Alonso A., Rodriguez L.A., Logroscino G., Hernan M.A. Gout and risk of Parkinson disease: a prospective study. Neurology 2007, 69:1696-1700.
    • (2007) Neurology , vol.69 , pp. 1696-1700
    • Alonso, A.1    Rodriguez, L.A.2    Logroscino, G.3    Hernan, M.A.4
  • 3
    • 77953477058 scopus 로고    scopus 로고
    • Gout, hyperuricemia, and Parkinson's disease: a protective effect?
    • Alonso A., Sovell K.A. Gout, hyperuricemia, and Parkinson's disease: a protective effect?. Curr. Rheumatol. Rep. 2010, 12:149-155.
    • (2010) Curr. Rheumatol. Rep. , vol.12 , pp. 149-155
    • Alonso, A.1    Sovell, K.A.2
  • 6
    • 34447547493 scopus 로고    scopus 로고
    • Low plasma uric acid level in Parkinson's disease
    • Annanmaki T., Muuronen A., Murros K. Low plasma uric acid level in Parkinson's disease. Mov. Disord. 2007, 22:1133-1137.
    • (2007) Mov. Disord. , vol.22 , pp. 1133-1137
    • Annanmaki, T.1    Muuronen, A.2    Murros, K.3
  • 9
    • 0035831189 scopus 로고    scopus 로고
    • Beta-amyloid-induced glial expression of both pro- and anti-inflammatory cytokines in cerebral cortex of aged transgenic Tg2576 mice with Alzheimer plaque pathology
    • Apelt J., Schliebs R. Beta-amyloid-induced glial expression of both pro- and anti-inflammatory cytokines in cerebral cortex of aged transgenic Tg2576 mice with Alzheimer plaque pathology. Brain Res. 2001, 894:21-30.
    • (2001) Brain Res. , vol.894 , pp. 21-30
    • Apelt, J.1    Schliebs, R.2
  • 12
    • 77649110090 scopus 로고    scopus 로고
    • The relationship between uric acid levels and Huntington's disease progression
    • Auinger P., Kieburtz K., McDermott M.P. The relationship between uric acid levels and Huntington's disease progression. Mov. Disord. 2010, 25:224-228.
    • (2010) Mov. Disord. , vol.25 , pp. 224-228
    • Auinger, P.1    Kieburtz, K.2    McDermott, M.P.3
  • 15
    • 34548670965 scopus 로고    scopus 로고
    • Inflammasomes in inflammatory disorders: the role of TLRs and their interactions with NLRs
    • Becker C.E., O'Neill L.A. Inflammasomes in inflammatory disorders: the role of TLRs and their interactions with NLRs. Semin. Immunopathol. 2007, 29:239-248.
    • (2007) Semin. Immunopathol. , vol.29 , pp. 239-248
    • Becker, C.E.1    O'Neill, L.A.2
  • 16
    • 84884507439 scopus 로고    scopus 로고
    • Microglia: multiple roles in surveillance, circuit shaping, and response to injury
    • Benarroch E.E. Microglia: multiple roles in surveillance, circuit shaping, and response to injury. Neurology 2013, 81:1079-1088.
    • (2013) Neurology , vol.81 , pp. 1079-1088
    • Benarroch, E.E.1
  • 17
    • 33845951211 scopus 로고    scopus 로고
    • DAMPs, PAMPs and alarmins: all we need to know about danger
    • Bianchi M.E. DAMPs, PAMPs and alarmins: all we need to know about danger. J. Leukoc. Biol. 2007, 81:1-5.
    • (2007) J. Leukoc. Biol. , vol.81 , pp. 1-5
    • Bianchi, M.E.1
  • 18
    • 79960810171 scopus 로고    scopus 로고
    • Heat shock proteins are no DAMPs, rather 'DAMPERs'
    • (Author reply 565)
    • Broere F., van der Zee R., van Eden W. Heat shock proteins are no DAMPs, rather 'DAMPERs'. Nat. Rev. Immunol. 2011, 11:565. (Author reply 565).
    • (2011) Nat. Rev. Immunol. , vol.11 , pp. 565
    • Broere, F.1    van der Zee, R.2    van Eden, W.3
  • 19
    • 0037454946 scopus 로고    scopus 로고
    • Inhibition of interleukin 1 receptor/Toll-like receptor signaling through the alternatively spliced, short form of MyD88 is due to its failure to recruit IRAK-4
    • Burns K., Janssens S., Brissoni B., Olivos N., Beyaert R., Tschopp J. Inhibition of interleukin 1 receptor/Toll-like receptor signaling through the alternatively spliced, short form of MyD88 is due to its failure to recruit IRAK-4. J. Exp. Med. 2003, 197:263-268.
    • (2003) J. Exp. Med. , vol.197 , pp. 263-268
    • Burns, K.1    Janssens, S.2    Brissoni, B.3    Olivos, N.4    Beyaert, R.5    Tschopp, J.6
  • 20
    • 33645312665 scopus 로고    scopus 로고
    • S100B protects LAN-5 neuroblastoma cells against Abeta amyloid-induced neurotoxicity via RAGE engagement at low doses but increases Abeta amyloid neurotoxicity at high doses
    • Businaro R., Leone S., Fabrizi C., Sorci G., Donato R., Lauro G.M., Fumagalli L. S100B protects LAN-5 neuroblastoma cells against Abeta amyloid-induced neurotoxicity via RAGE engagement at low doses but increases Abeta amyloid neurotoxicity at high doses. J. Neurosci. Res. 2006, 83:897-906.
    • (2006) J. Neurosci. Res. , vol.83 , pp. 897-906
    • Businaro, R.1    Leone, S.2    Fabrizi, C.3    Sorci, G.4    Donato, R.5    Lauro, G.M.6    Fumagalli, L.7
  • 21
    • 67349276645 scopus 로고    scopus 로고
    • Amyloid precursor protein and alpha synuclein translation, implications for iron and inflammation in neurodegenerative diseases
    • Cahill C.M., Lahiri D.K., Huang X., Rogers J.T. Amyloid precursor protein and alpha synuclein translation, implications for iron and inflammation in neurodegenerative diseases. Biochim. Biophys. Acta 2009, 1790:615-628.
    • (2009) Biochim. Biophys. Acta , vol.1790 , pp. 615-628
    • Cahill, C.M.1    Lahiri, D.K.2    Huang, X.3    Rogers, J.T.4
  • 22
    • 84856468940 scopus 로고    scopus 로고
    • Metabolic dysfunction in Alzheimer's disease and related neurodegenerative disorders
    • Cai H., Cong W.N., Ji S., Rothman S., Maudsley S., Martin B. Metabolic dysfunction in Alzheimer's disease and related neurodegenerative disorders. Curr. Alzheimer Res. 2012, 9:5-17.
    • (2012) Curr. Alzheimer Res. , vol.9 , pp. 5-17
    • Cai, H.1    Cong, W.N.2    Ji, S.3    Rothman, S.4    Maudsley, S.5    Martin, B.6
  • 23
    • 14944364559 scopus 로고    scopus 로고
    • Inflammation, neurodegenerative diseases, and environmental exposures
    • Campbell A. Inflammation, neurodegenerative diseases, and environmental exposures. Ann. N.Y. Acad. Sci. 2004, 1035:117-132.
    • (2004) Ann. N.Y. Acad. Sci. , vol.1035 , pp. 117-132
    • Campbell, A.1
  • 24
    • 77952413047 scopus 로고    scopus 로고
    • Inflammasome signaling at the heart of central nervous system pathology
    • Chakraborty S., Kaushik D.K., Gupta M., Basu A. Inflammasome signaling at the heart of central nervous system pathology. J. Neurosci. Res. 2010, 88:1615-1631.
    • (2010) J. Neurosci. Res. , vol.88 , pp. 1615-1631
    • Chakraborty, S.1    Kaushik, D.K.2    Gupta, M.3    Basu, A.4
  • 27
    • 78649526394 scopus 로고    scopus 로고
    • Sterile inflammation: sensing and reacting to damage
    • Chen G.Y., Nunez G. Sterile inflammation: sensing and reacting to damage. Nat. Rev. Immunol. 2010, 10:826-837.
    • (2010) Nat. Rev. Immunol. , vol.10 , pp. 826-837
    • Chen, G.Y.1    Nunez, G.2
  • 28
    • 33847772938 scopus 로고    scopus 로고
    • The killing of neurons by beta-amyloid peptides, prions, and pro-inflammatory cytokines
    • Chiarini A., Dal Pra I., Whitfield J.F., Armato U. The killing of neurons by beta-amyloid peptides, prions, and pro-inflammatory cytokines. Ital. J. Anat. Embryol. 2006, 111:221-246.
    • (2006) Ital. J. Anat. Embryol. , vol.111 , pp. 221-246
    • Chiarini, A.1    Dal Pra, I.2    Whitfield, J.F.3    Armato, U.4
  • 30
    • 0034125277 scopus 로고    scopus 로고
    • Advances in signalling by extracellular nucleotides. The role and transduction mechanisms of P2Y receptors
    • Communi D., Janssens R., Suarez-Huerta N., Robaye B., Boeynaems J.M. Advances in signalling by extracellular nucleotides. The role and transduction mechanisms of P2Y receptors. Cell Signal. 2000, 12:351-360.
    • (2000) Cell Signal. , vol.12 , pp. 351-360
    • Communi, D.1    Janssens, R.2    Suarez-Huerta, N.3    Robaye, B.4    Boeynaems, J.M.5
  • 31
    • 84859731658 scopus 로고    scopus 로고
    • The immunology of neurodegeneration
    • Czirr E., Wyss-Coray T. The immunology of neurodegeneration. J. Clin. Invest. 2012, 122:1156-1163.
    • (2012) J. Clin. Invest. , vol.122 , pp. 1156-1163
    • Czirr, E.1    Wyss-Coray, T.2
  • 32
    • 84896702066 scopus 로고    scopus 로고
    • Activation and regulation of cellular inflammasomes: gaps in our knowledge for central nervous system injury
    • de Rivero Vaccari J.P., Dietrich W.D., Keane R.W. Activation and regulation of cellular inflammasomes: gaps in our knowledge for central nervous system injury. J. Cereb. Blood Flow Metab. 2014, 34:369-375.
    • (2014) J. Cereb. Blood Flow Metab. , vol.34 , pp. 369-375
    • de Rivero Vaccari, J.P.1    Dietrich, W.D.2    Keane, R.W.3
  • 33
    • 67649360450 scopus 로고    scopus 로고
    • Therapeutic neutralization of the NLRP1 inflammasome reduces the innate immune response and improves histopathology after traumatic brain injury
    • de Rivero Vaccari J.P., Lotocki G., Alonso O.F., Bramlett H.M., Dietrich W.D., Keane R.W. Therapeutic neutralization of the NLRP1 inflammasome reduces the innate immune response and improves histopathology after traumatic brain injury. J. Cereb. Blood Flow Metab. 2009, 29:1251-1261.
    • (2009) J. Cereb. Blood Flow Metab. , vol.29 , pp. 1251-1261
    • de Rivero Vaccari, J.P.1    Lotocki, G.2    Alonso, O.F.3    Bramlett, H.M.4    Dietrich, W.D.5    Keane, R.W.6
  • 36
    • 0141459720 scopus 로고    scopus 로고
    • The nuclear protein HMGB1, a new kind of chemokine?
    • Degryse B., de Virgilio M. The nuclear protein HMGB1, a new kind of chemokine?. FEBS Lett. 2003, 553:11-17.
    • (2003) FEBS Lett. , vol.553 , pp. 11-17
    • Degryse, B.1    de Virgilio, M.2
  • 39
    • 62649139025 scopus 로고    scopus 로고
    • Immunological and inflammatory functions of the interleukin-1 family
    • Dinarello C.A. Immunological and inflammatory functions of the interleukin-1 family. Annu. Rev. Immunol. 2009, 27:519-550.
    • (2009) Annu. Rev. Immunol. , vol.27 , pp. 519-550
    • Dinarello, C.A.1
  • 44
    • 3242693560 scopus 로고    scopus 로고
    • Mini-review: the nuclear protein HMGB1 as a proinflammatory mediator
    • Erlandsson Harris H., Andersson U. Mini-review: the nuclear protein HMGB1 as a proinflammatory mediator. Eur. J. Immunol. 2004, 34:1503-1512.
    • (2004) Eur. J. Immunol. , vol.34 , pp. 1503-1512
    • Erlandsson Harris, H.1    Andersson, U.2
  • 45
    • 44149085664 scopus 로고    scopus 로고
    • S100B induces tau protein hyperphosphorylation via Dickopff-1 up-regulation and disrupts the Wnt pathway in human neural stem cells
    • Esposito G., Scuderi C., Lu J., Savani C., De Filippis D., Iuvone T., Steardo L., Sheen V., Steardo L. S100B induces tau protein hyperphosphorylation via Dickopff-1 up-regulation and disrupts the Wnt pathway in human neural stem cells. J. Cell Mol. Med. 2008, 12:914-927.
    • (2008) J. Cell Mol. Med. , vol.12 , pp. 914-927
    • Esposito, G.1    Scuderi, C.2    Lu, J.3    Savani, C.4    De Filippis, D.5    Iuvone, T.6    Steardo, L.7    Sheen, V.8    Steardo, L.9
  • 46
    • 84867450111 scopus 로고    scopus 로고
    • HMGB1 in development and diseases of the central nervous system
    • Fang P., Schachner M., Shen Y.Q. HMGB1 in development and diseases of the central nervous system. Mol. Neurobiol. 2012, 45:499-506.
    • (2012) Mol. Neurobiol. , vol.45 , pp. 499-506
    • Fang, P.1    Schachner, M.2    Shen, Y.Q.3
  • 47
    • 52049099108 scopus 로고    scopus 로고
    • Assembly, purification, and assay of the activity of the ASC pyroptosome
    • Fernandes-Alnemri T., Alnemri E.S. Assembly, purification, and assay of the activity of the ASC pyroptosome. Methods Enzymol. 2008, 442:251-270.
    • (2008) Methods Enzymol. , vol.442 , pp. 251-270
    • Fernandes-Alnemri, T.1    Alnemri, E.S.2
  • 50
    • 7044238416 scopus 로고    scopus 로고
    • Neurodegenerative diseases: a decade of discoveries paves the way for therapeutic breakthroughs
    • Forman M.S., Trojanowski J.Q., Lee V.M. Neurodegenerative diseases: a decade of discoveries paves the way for therapeutic breakthroughs. Nat. Med. 2004, 10:1055-1063.
    • (2004) Nat. Med. , vol.10 , pp. 1055-1063
    • Forman, M.S.1    Trojanowski, J.Q.2    Lee, V.M.3
  • 51
    • 34547346782 scopus 로고    scopus 로고
    • Relevance of high-mobility group protein box 1 to neurodegeneration
    • Fossati S., Chiarugi A. Relevance of high-mobility group protein box 1 to neurodegeneration. Int. Rev. Neurobiol. 2007, 82:137-148.
    • (2007) Int. Rev. Neurobiol. , vol.82 , pp. 137-148
    • Fossati, S.1    Chiarugi, A.2
  • 52
    • 34548699677 scopus 로고    scopus 로고
    • The role of the inflammasome in cellular responses to toxins and bacterial effectors
    • Freche B., Reig N., van der Goot F.G. The role of the inflammasome in cellular responses to toxins and bacterial effectors. Semin. Immunopathol. 2007, 29:249-260.
    • (2007) Semin. Immunopathol. , vol.29 , pp. 249-260
    • Freche, B.1    Reig, N.2    van der Goot, F.G.3
  • 53
    • 0037417220 scopus 로고    scopus 로고
    • Apoptosis and caspases in neurodegenerative diseases
    • Friedlander R.M. Apoptosis and caspases in neurodegenerative diseases. N. Engl. J. Med. 2003, 348:1365-1375.
    • (2003) N. Engl. J. Med. , vol.348 , pp. 1365-1375
    • Friedlander, R.M.1
  • 55
    • 47749126515 scopus 로고    scopus 로고
    • Why neurodegenerative diseases are progressive: uncontrolled inflammation drives disease progression
    • Gao H.M., Hong J.S. Why neurodegenerative diseases are progressive: uncontrolled inflammation drives disease progression. Trends Immunol. 2008, 29:357-365.
    • (2008) Trends Immunol. , vol.29 , pp. 357-365
    • Gao, H.M.1    Hong, J.S.2
  • 56
    • 79955921784 scopus 로고    scopus 로고
    • Neuroinflammation and alpha-synuclein dysfunction potentiate each other, driving chronic progression of neurodegeneration in a mouse model of Parkinson's disease
    • Gao H.M., Zhang F., Zhou H., Kam W., Wilson B., Hong J.S. Neuroinflammation and alpha-synuclein dysfunction potentiate each other, driving chronic progression of neurodegeneration in a mouse model of Parkinson's disease. Environ. Health Perspect. 2011, 119:807-814.
    • (2011) Environ. Health Perspect. , vol.119 , pp. 807-814
    • Gao, H.M.1    Zhang, F.2    Zhou, H.3    Kam, W.4    Wilson, B.5    Hong, J.S.6
  • 57
    • 78751502344 scopus 로고    scopus 로고
    • HMGB1 acts on microglia Mac1 to mediate chronic neuroinflammation that drives progressive neurodegeneration
    • Gao H.M., Zhou H., Zhang F., Wilson B.C., Kam W., Hong J.S. HMGB1 acts on microglia Mac1 to mediate chronic neuroinflammation that drives progressive neurodegeneration. J. Neurosci. 2011, 31:1081-1092.
    • (2011) J. Neurosci. , vol.31 , pp. 1081-1092
    • Gao, H.M.1    Zhou, H.2    Zhang, F.3    Wilson, B.C.4    Kam, W.5    Hong, J.S.6
  • 58
    • 0036775236 scopus 로고    scopus 로고
    • The nuclear protein HMGB1 is secreted by monocytes via a non-classical, vesicle-mediated secretory pathway
    • Gardella S., Andrei C., Ferrera D., Lotti L.V., Torrisi M.R., Bianchi M.E., Rubartelli A. The nuclear protein HMGB1 is secreted by monocytes via a non-classical, vesicle-mediated secretory pathway. EMBO Rep. 2002, 3:995-1001.
    • (2002) EMBO Rep. , vol.3 , pp. 995-1001
    • Gardella, S.1    Andrei, C.2    Ferrera, D.3    Lotti, L.V.4    Torrisi, M.R.5    Bianchi, M.E.6    Rubartelli, A.7
  • 60
    • 84880884622 scopus 로고    scopus 로고
    • Pediatric sepsis-Part V: Extracellular heat shock proteins: alarmins for the host immune system
    • Giuliano J.S., Lahni P.M., Wong H.R., Wheeler D.S. Pediatric sepsis-Part V: Extracellular heat shock proteins: alarmins for the host immune system. Open Inflamm. J. 2011, 4:49-60.
    • (2011) Open Inflamm. J. , vol.4 , pp. 49-60
    • Giuliano, J.S.1    Lahni, P.M.2    Wong, H.R.3    Wheeler, D.S.4
  • 61
    • 33845999595 scopus 로고    scopus 로고
    • Is inflammaging an auto[innate]immunity subclinical syndrome?
    • Giunta S. Is inflammaging an auto[innate]immunity subclinical syndrome?. Immun. Ageing: IA 2006, 3:12.
    • (2006) Immun. Ageing: IA , vol.3 , pp. 12
    • Giunta, S.1
  • 62
    • 84877103526 scopus 로고    scopus 로고
    • Thinking laterally about neurodegenerative proteinopathies
    • Golde T.E., Borchelt D.R., Giasson B.I., Lewis J. Thinking laterally about neurodegenerative proteinopathies. J. Clin. Invest. 2013, 123:1847-1855.
    • (2013) J. Clin. Invest. , vol.123 , pp. 1847-1855
    • Golde, T.E.1    Borchelt, D.R.2    Giasson, B.I.3    Lewis, J.4
  • 63
    • 57249084239 scopus 로고    scopus 로고
    • Neuronal cell death in neurodegenerative diseases: recurring themes around protein handling
    • Gorman A.M. Neuronal cell death in neurodegenerative diseases: recurring themes around protein handling. J. Cell. Mol. Med. 2008, 12:2263-2280.
    • (2008) J. Cell. Mol. Med. , vol.12 , pp. 2263-2280
    • Gorman, A.M.1
  • 64
    • 33644869901 scopus 로고    scopus 로고
    • Inflammation and neurodegenerative diseases
    • Griffin W.S. Inflammation and neurodegenerative diseases. Am. J. Clin. Nutr. 2006, 83:470S-474S.
    • (2006) Am. J. Clin. Nutr. , vol.83 , pp. 470S-474S
    • Griffin, W.S.1
  • 67
    • 33747751590 scopus 로고    scopus 로고
    • Alarmin(g) news about danger: workshop on innate danger signals and HMGB1
    • Harris H.E., Raucci A. Alarmin(g) news about danger: workshop on innate danger signals and HMGB1. EMBO Rep. 2006, 7:774-778.
    • (2006) EMBO Rep. , vol.7 , pp. 774-778
    • Harris, H.E.1    Raucci, A.2
  • 68
    • 77956238504 scopus 로고    scopus 로고
    • Mitochondrial damage associated molecular patterns from femoral reamings activate neutrophils through formyl peptide receptors and P44/42 MAP kinase
    • Hauser C.J., Sursal T., Rodriguez E.K., Appleton P.T., Zhang Q., Itagaki K. Mitochondrial damage associated molecular patterns from femoral reamings activate neutrophils through formyl peptide receptors and P44/42 MAP kinase. J. Orthopaed. Trauma 2010, 24:534-538.
    • (2010) J. Orthopaed. Trauma , vol.24 , pp. 534-538
    • Hauser, C.J.1    Sursal, T.2    Rodriguez, E.K.3    Appleton, P.T.4    Zhang, Q.5    Itagaki, K.6
  • 69
    • 0036580943 scopus 로고    scopus 로고
    • S100 proteins: structure, functions and pathology
    • Heizmann C.W., Fritz G., Schafer B.W. S100 proteins: structure, functions and pathology. Front. Biosci. 2002, 7:d1356-d1368.
    • (2002) Front. Biosci. , vol.7 , pp. d1356-d1368
    • Heizmann, C.W.1    Fritz, G.2    Schafer, B.W.3
  • 71
    • 33847613885 scopus 로고    scopus 로고
    • Inflammatory processes in Alzheimer's disease
    • Heneka M.T., O'Banion M.K. Inflammatory processes in Alzheimer's disease. J. Neuroimmunol. 2007, 184:69-91.
    • (2007) J. Neuroimmunol. , vol.184 , pp. 69-91
    • Heneka, M.T.1    O'Banion, M.K.2
  • 72
    • 34249804796 scopus 로고    scopus 로고
    • Dual role of inflammation in CNS disease
    • (Discussion S91-56)
    • Hohlfeld R., Kerschensteiner M., Meinl E. Dual role of inflammation in CNS disease. Neurology 2007, 68:S58-S63. (Discussion S91-56).
    • (2007) Neurology , vol.68 , pp. S58-S63
    • Hohlfeld, R.1    Kerschensteiner, M.2    Meinl, E.3
  • 73
    • 84888060868 scopus 로고    scopus 로고
    • P35 deficiency accelerates HMGB-1-mediated neuronal death in the early stages of an Alzheimer's disease mouse model
    • Jang A., Liew H., Kim Y.M., Choi H., Kim S., Lee S.H., Ohshima T., Mikoshiba K., Suh Y.H. p35 deficiency accelerates HMGB-1-mediated neuronal death in the early stages of an Alzheimer's disease mouse model. Curr. Alzheimer Res. 2013, 10:829-843.
    • (2013) Curr. Alzheimer Res. , vol.10 , pp. 829-843
    • Jang, A.1    Liew, H.2    Kim, Y.M.3    Choi, H.4    Kim, S.5    Lee, S.H.6    Ohshima, T.7    Mikoshiba, K.8    Suh, Y.H.9
  • 75
    • 84879125279 scopus 로고    scopus 로고
    • Recognition of damage-associated molecular patterns related to nucleic acids during inflammation and vaccination
    • Jounai N., Kobiyama K., Takeshita F., Ishii K.J. Recognition of damage-associated molecular patterns related to nucleic acids during inflammation and vaccination. Front. Cell. Infect. Microbiol. 2012, 2:168.
    • (2012) Front. Cell. Infect. Microbiol. , vol.2 , pp. 168
    • Jounai, N.1    Kobiyama, K.2    Takeshita, F.3    Ishii, K.J.4
  • 76
    • 84859864546 scopus 로고    scopus 로고
    • Circulating cell-free DNA is associated with mortality and inflammatory markers in nonagenarians: the Vitality 90+ study
    • Jylhava J., Jylha M., Lehtimaki T., Hervonen A., Hurme M. Circulating cell-free DNA is associated with mortality and inflammatory markers in nonagenarians: the Vitality 90+ study. Exp. Gerontol. 2012, 47:372-378.
    • (2012) Exp. Gerontol. , vol.47 , pp. 372-378
    • Jylhava, J.1    Jylha, M.2    Lehtimaki, T.3    Hervonen, A.4    Hurme, M.5
  • 77
    • 79251593840 scopus 로고    scopus 로고
    • Aging is associated with quantitative and qualitative changes in circulating cell-free DNA: the Vitality 90+ study
    • Jylhava J., Kotipelto T., Raitala A., Jylha M., Hervonen A., Hurme M. Aging is associated with quantitative and qualitative changes in circulating cell-free DNA: the Vitality 90+ study. Mech. Ageing Dev. 2011, 132:20-26.
    • (2011) Mech. Ageing Dev. , vol.132 , pp. 20-26
    • Jylhava, J.1    Kotipelto, T.2    Raitala, A.3    Jylha, M.4    Hervonen, A.5    Hurme, M.6
  • 78
    • 84877808128 scopus 로고    scopus 로고
    • Characterization of the role of distinct plasma cell-free DNA species in age-associated inflammation and frailty
    • Jylhava J., Nevalainen T., Marttila S., Jylha M., Hervonen A., Hurme M. Characterization of the role of distinct plasma cell-free DNA species in age-associated inflammation and frailty. Aging Cell 2013, 12:388-397.
    • (2013) Aging Cell , vol.12 , pp. 388-397
    • Jylhava, J.1    Nevalainen, T.2    Marttila, S.3    Jylha, M.4    Hervonen, A.5    Hurme, M.6
  • 80
    • 20544439885 scopus 로고    scopus 로고
    • Enhanced hippocampal neurogenesis by intraventricular S100B infusion is associated with improved cognitive recovery after traumatic brain injury
    • Kleindienst A., McGinn M.J., Harvey H.B., Colello R.J., Hamm R.J., Bullock M.R. Enhanced hippocampal neurogenesis by intraventricular S100B infusion is associated with improved cognitive recovery after traumatic brain injury. J. Neurotrauma 2005, 22:645-655.
    • (2005) J. Neurotrauma , vol.22 , pp. 645-655
    • Kleindienst, A.1    McGinn, M.J.2    Harvey, H.B.3    Colello, R.J.4    Hamm, R.J.5    Bullock, M.R.6
  • 82
    • 42249115877 scopus 로고    scopus 로고
    • Neuroinflammation mediated by IL-1beta increases susceptibility of dopamine neurons to degeneration in an animal model of Parkinson's disease
    • Koprich J.B., Reske-Nielsen C., Mithal P., Isacson O. Neuroinflammation mediated by IL-1beta increases susceptibility of dopamine neurons to degeneration in an animal model of Parkinson's disease. J. Neuroinflamm. 2008, 5:8.
    • (2008) J. Neuroinflamm. , vol.5 , pp. 8
    • Koprich, J.B.1    Reske-Nielsen, C.2    Mithal, P.3    Isacson, O.4
  • 87
    • 84874217400 scopus 로고    scopus 로고
    • The danger theory in view of the injury hypothesis: 20 years later
    • Land W.G., Messmer K. The danger theory in view of the injury hypothesis: 20 years later. Front. Immunol. 2012, 3:349.
    • (2012) Front. Immunol. , vol.3 , pp. 349
    • Land, W.G.1    Messmer, K.2
  • 90
    • 17144371314 scopus 로고    scopus 로고
    • TLR2 signaling in chondrocytes drives calcium pyrophosphate dihydrate and monosodium urate crystal-induced nitric oxide generation
    • Liu-Bryan R., Pritzker K., Firestein G.S., Terkeltaub R. TLR2 signaling in chondrocytes drives calcium pyrophosphate dihydrate and monosodium urate crystal-induced nitric oxide generation. J. Immunol. 2005, 174:5016-5023.
    • (2005) J. Immunol. , vol.174 , pp. 5016-5023
    • Liu-Bryan, R.1    Pritzker, K.2    Firestein, G.S.3    Terkeltaub, R.4
  • 91
    • 25444454295 scopus 로고    scopus 로고
    • Innate immunity conferred by Toll-like receptors 2 and 4 and myeloid differentiation factor 88 expression is pivotal to monosodium urate monohydrate crystal-induced inflammation
    • Liu-Bryan R., Scott P., Sydlaske A., Rose D.M., Terkeltaub R. Innate immunity conferred by Toll-like receptors 2 and 4 and myeloid differentiation factor 88 expression is pivotal to monosodium urate monohydrate crystal-induced inflammation. Arthritis Rheum. 2005, 52:2936-2946.
    • (2005) Arthritis Rheum. , vol.52 , pp. 2936-2946
    • Liu-Bryan, R.1    Scott, P.2    Sydlaske, A.3    Rose, D.M.4    Terkeltaub, R.5
  • 92
    • 0037215645 scopus 로고    scopus 로고
    • Role of microglia in inflammation-mediated neurodegenerative diseases: mechanisms and strategies for therapeutic intervention
    • Liu B., Hong J.S. Role of microglia in inflammation-mediated neurodegenerative diseases: mechanisms and strategies for therapeutic intervention. J. Pharmacol. Exp. Ther. 2003, 304:1-7.
    • (2003) J. Pharmacol. Exp. Ther. , vol.304 , pp. 1-7
    • Liu, B.1    Hong, J.S.2
  • 93
    • 0032722186 scopus 로고    scopus 로고
    • Heat shock protein suppresses the senescent lung cytokine response to acute endotoxemia
    • LoCicero J., Xu X., Zhang L. Heat shock protein suppresses the senescent lung cytokine response to acute endotoxemia. Ann. Thorac. Surg. 1999, 68:1150-1153.
    • (1999) Ann. Thorac. Surg. , vol.68 , pp. 1150-1153
    • LoCicero, J.1    Xu, X.2    Zhang, L.3
  • 94
    • 17144376810 scopus 로고    scopus 로고
    • High-mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal
    • Lotze M.T., Tracey K.J. High-mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal. Nat. Rev. Immunol. 2005, 5:331-342.
    • (2005) Nat. Rev. Immunol. , vol.5 , pp. 331-342
    • Lotze, M.T.1    Tracey, K.J.2
  • 96
    • 77953153023 scopus 로고    scopus 로고
    • The mitochondrion-a Trojan horse that kicks off inflammation
    • Manfredi A.A., Rovere-Querini P. The mitochondrion-a Trojan horse that kicks off inflammation. N. Engl. J. Med. 2010, 362:2132-2134.
    • (2010) N. Engl. J. Med. , vol.362 , pp. 2132-2134
    • Manfredi, A.A.1    Rovere-Querini, P.2
  • 98
    • 32944468985 scopus 로고    scopus 로고
    • Gout-associated uric acid crystals activate the NALP3 inflammasome
    • Martinon F., Petrilli V., Mayor A., Tardivel A., Tschopp J. Gout-associated uric acid crystals activate the NALP3 inflammasome. Nature 2006, 440:237-241.
    • (2006) Nature , vol.440 , pp. 237-241
    • Martinon, F.1    Petrilli, V.2    Mayor, A.3    Tardivel, A.4    Tschopp, J.5
  • 99
    • 84862835766 scopus 로고    scopus 로고
    • Degraded mitochondrial DNA is a newly identified subtype of the damage associated molecular pattern (DAMP) family and possible trigger of neurodegeneration
    • Mathew A., Lindsley T.A., Sheridan A., Bhoiwala D.L., Hushmendy S.F., Yager E.J., Ruggiero E.A., Crawford D.R. Degraded mitochondrial DNA is a newly identified subtype of the damage associated molecular pattern (DAMP) family and possible trigger of neurodegeneration. J. Alzheimers Dis. 2012, 30:617-627.
    • (2012) J. Alzheimers Dis. , vol.30 , pp. 617-627
    • Mathew, A.1    Lindsley, T.A.2    Sheridan, A.3    Bhoiwala, D.L.4    Hushmendy, S.F.5    Yager, E.J.6    Ruggiero, E.A.7    Crawford, D.R.8
  • 100
    • 0028201732 scopus 로고
    • Tolerance, danger, and the extended family
    • Matzinger P. Tolerance, danger, and the extended family. Annu. Rev. Immunol. 1994, 12:991-1045.
    • (1994) Annu. Rev. Immunol. , vol.12 , pp. 991-1045
    • Matzinger, P.1
  • 101
    • 0032191916 scopus 로고    scopus 로고
    • An innate sense of danger
    • Matzinger P. An innate sense of danger. Semin. Immunol. 1998, 10:399-415.
    • (1998) Semin. Immunol. , vol.10 , pp. 399-415
    • Matzinger, P.1
  • 102
    • 0036293726 scopus 로고    scopus 로고
    • An innate sense of danger
    • Matzinger P. An innate sense of danger. Ann. N.Y. Acad. Sci. 2002, 961:341-342.
    • (2002) Ann. N.Y. Acad. Sci. , vol.961 , pp. 341-342
    • Matzinger, P.1
  • 103
    • 82355160899 scopus 로고    scopus 로고
    • Heightened inflammasome activation is linked to age-related cognitive impairment in Fischer 344 rats
    • Mawhinney L.J., de Rivero Vaccari J.P., Dale G.A., Keane R.W., Bramlett H.M. Heightened inflammasome activation is linked to age-related cognitive impairment in Fischer 344 rats. BMC Neurosci. 2011, 12:123.
    • (2011) BMC Neurosci. , vol.12 , pp. 123
    • Mawhinney, L.J.1    de Rivero Vaccari, J.P.2    Dale, G.A.3    Keane, R.W.4    Bramlett, H.M.5
  • 104
    • 80055009332 scopus 로고    scopus 로고
    • High-mobility group box-1 impairs memory in mice through both toll-like receptor 4 and receptor for advanced glycation end products
    • Mazarati A., Maroso M., Iori V., Vezzani A., Carli M. High-mobility group box-1 impairs memory in mice through both toll-like receptor 4 and receptor for advanced glycation end products. Exp. Neurol. 2011, 232:143-148.
    • (2011) Exp. Neurol. , vol.232 , pp. 143-148
    • Mazarati, A.1    Maroso, M.2    Iori, V.3    Vezzani, A.4    Carli, M.5
  • 105
    • 0026699919 scopus 로고
    • Immune responses in brains of Alzheimer's and Parkinson's disease patients: hypothesis and reality
    • McRae A., Dahlstrom A. Immune responses in brains of Alzheimer's and Parkinson's disease patients: hypothesis and reality. Rev. Neurosci. 1992, 3:79-98.
    • (1992) Rev. Neurosci. , vol.3 , pp. 79-98
    • McRae, A.1    Dahlstrom, A.2
  • 106
    • 80052626087 scopus 로고    scopus 로고
    • The NLRP3 inflammasome in health and disease: the good, the bad and the ugly
    • Menu P., Vince J.E. The NLRP3 inflammasome in health and disease: the good, the bad and the ugly. Clin. Exp. Immunol. 2011, 166:1-15.
    • (2011) Clin. Exp. Immunol. , vol.166 , pp. 1-15
    • Menu, P.1    Vince, J.E.2
  • 107
    • 84873540749 scopus 로고    scopus 로고
    • Chaperone-like activity of high-mobility group box 1 protein and its role in reducing the formation of polyglutamine aggregates
    • Min H.J., Ko E.A., Wu J., Kim E.S., Kwon M.K., Kwak M.S., Choi J.E., Lee J.E., Shin J.S. Chaperone-like activity of high-mobility group box 1 protein and its role in reducing the formation of polyglutamine aggregates. J. Immunol. 2013, 190:1797-1806.
    • (2013) J. Immunol. , vol.190 , pp. 1797-1806
    • Min, H.J.1    Ko, E.A.2    Wu, J.3    Kim, E.S.4    Kwon, M.K.5    Kwak, M.S.6    Choi, J.E.7    Lee, J.E.8    Shin, J.S.9
  • 108
    • 20444466786 scopus 로고    scopus 로고
    • Role of inflammation in neurodegenerative diseases
    • Minghetti L. Role of inflammation in neurodegenerative diseases. Curr. Opin. Neurol. 2005, 18:315-321.
    • (2005) Curr. Opin. Neurol. , vol.18 , pp. 315-321
    • Minghetti, L.1
  • 109
    • 75849133906 scopus 로고    scopus 로고
    • Overexpression of human S100B exacerbates cerebral amyloidosis and gliosis in the Tg2576 mouse model of Alzheimer's disease
    • Mori T., Koyama N., Arendash G.W., Horikoshi-Sakuraba Y., Tan J., Town T. Overexpression of human S100B exacerbates cerebral amyloidosis and gliosis in the Tg2576 mouse model of Alzheimer's disease. Glia 2010, 58:300-314.
    • (2010) Glia , vol.58 , pp. 300-314
    • Mori, T.1    Koyama, N.2    Arendash, G.W.3    Horikoshi-Sakuraba, Y.4    Tan, J.5    Town, T.6
  • 113
    • 33947510303 scopus 로고    scopus 로고
    • Synergistic and differential modulation of immune responses by Hsp60 and lipopolysaccharide
    • Osterloh A., Kalinke U., Weiss S., Fleischer B., Breloer M. Synergistic and differential modulation of immune responses by Hsp60 and lipopolysaccharide. J. Biol. Chem. 2007, 282:4669-4680.
    • (2007) J. Biol. Chem. , vol.282 , pp. 4669-4680
    • Osterloh, A.1    Kalinke, U.2    Weiss, S.3    Fleischer, B.4    Breloer, M.5
  • 114
    • 84924052001 scopus 로고    scopus 로고
    • Microglial NLRP3 inflammasome activation mediates IL-1beta-related inflammation in prefrontal cortex of depressive rats
    • Pan Y., Chen X.Y., Zhang Q.Y., Kong L.D. Microglial NLRP3 inflammasome activation mediates IL-1beta-related inflammation in prefrontal cortex of depressive rats. Brain Behav. Immun. 2014, 40:90-100.
    • (2014) Brain Behav. Immun. , vol.40 , pp. 90-100
    • Pan, Y.1    Chen, X.Y.2    Zhang, Q.Y.3    Kong, L.D.4
  • 115
    • 34047270416 scopus 로고    scopus 로고
    • Pannexin-1 couples to maitotoxin- and nigericin-induced interleukin-1beta release through a dye uptake-independent pathway
    • Pelegrin P., Surprenant A. Pannexin-1 couples to maitotoxin- and nigericin-induced interleukin-1beta release through a dye uptake-independent pathway. J. Biol. Chem. 2007, 282:2386-2394.
    • (2007) J. Biol. Chem. , vol.282 , pp. 2386-2394
    • Pelegrin, P.1    Surprenant, A.2
  • 117
    • 84872451259 scopus 로고    scopus 로고
    • The CARD plays a critical role in ASC foci formation and inflammasome signalling
    • Proell M., Gerlic M., Mace P.D., Reed J.C., Riedl S.J. The CARD plays a critical role in ASC foci formation and inflammasome signalling. Biochem. J. 2013, 449:613-621.
    • (2013) Biochem. J. , vol.449 , pp. 613-621
    • Proell, M.1    Gerlic, M.2    Mace, P.D.3    Reed, J.C.4    Riedl, S.J.5
  • 120
    • 69249100372 scopus 로고    scopus 로고
    • RAGE: therapeutic target and biomarker of the inflammatory response-the evidence mounts
    • Ramasamy R., Yan S.F., Schmidt A.M. RAGE: therapeutic target and biomarker of the inflammatory response-the evidence mounts. J. Leukocyte Biol. 2009, 86:505-512.
    • (2009) J. Leukocyte Biol. , vol.86 , pp. 505-512
    • Ramasamy, R.1    Yan, S.F.2    Schmidt, A.M.3
  • 121
    • 78149492695 scopus 로고    scopus 로고
    • PSAPP mice exhibit regionally selective reductions in gliosis and plaque deposition in response to S100B ablation
    • Roltsch E., Holcomb L., Young K.A., Marks A., Zimmer D.B. PSAPP mice exhibit regionally selective reductions in gliosis and plaque deposition in response to S100B ablation. J. Neuroinflamm. 2010, 7:78.
    • (2010) J. Neuroinflamm. , vol.7 , pp. 78
    • Roltsch, E.1    Holcomb, L.2    Young, K.A.3    Marks, A.4    Zimmer, D.B.5
  • 122
    • 33845804424 scopus 로고    scopus 로고
    • Uric acid reduces brain damage and improves the benefits of rt-PA in a rat model of thromboembolic stroke
    • Romanos E., Planas A.M., Amaro S., Chamorro A. Uric acid reduces brain damage and improves the benefits of rt-PA in a rat model of thromboembolic stroke. J. Cereb. Blood Flow Metab. 2007, 27:14-20.
    • (2007) J. Cereb. Blood Flow Metab. , vol.27 , pp. 14-20
    • Romanos, E.1    Planas, A.M.2    Amaro, S.3    Chamorro, A.4
  • 124
    • 0029669991 scopus 로고    scopus 로고
    • The S100 family of EF-hand calcium-binding proteins: functions and pathology
    • Schafer B.W., Heizmann C.W. The S100 family of EF-hand calcium-binding proteins: functions and pathology. Trends Biochem. Sci. 1996, 21:134-140.
    • (1996) Trends Biochem. Sci. , vol.21 , pp. 134-140
    • Schafer, B.W.1    Heizmann, C.W.2
  • 125
    • 84894350781 scopus 로고    scopus 로고
    • HMGB1 is involved in autophagy inhibition caused by SNCA/alpha-synuclein overexpression: a process modulated by the natural autophagy inducer corynoxine B
    • Song J.X., Lu J.H., Liu L.F., Chen L.L., Durairajan S.S., Yue Z., Zhang H.Q., Li M. HMGB1 is involved in autophagy inhibition caused by SNCA/alpha-synuclein overexpression: a process modulated by the natural autophagy inducer corynoxine B. Autophagy 2014, 10:144-154.
    • (2014) Autophagy , vol.10 , pp. 144-154
    • Song, J.X.1    Lu, J.H.2    Liu, L.F.3    Chen, L.L.4    Durairajan, S.S.5    Yue, Z.6    Zhang, H.Q.7    Li, M.8
  • 128
    • 77955199612 scopus 로고    scopus 로고
    • Heat shock proteins: cellular and molecular mechanisms in the central nervous system
    • Stetler R.A., Gan Y., Zhang W., Liou A.K., Gao Y., Cao G., Chen J. Heat shock proteins: cellular and molecular mechanisms in the central nervous system. Prog. Neurobiol. 2010, 92:184-211.
    • (2010) Prog. Neurobiol. , vol.92 , pp. 184-211
    • Stetler, R.A.1    Gan, Y.2    Zhang, W.3    Liou, A.K.4    Gao, Y.5    Cao, G.6    Chen, J.7
  • 129
    • 84900017196 scopus 로고    scopus 로고
    • Immune responses in Parkinson's disease: interplay between central and peripheral immune systems
    • Su X., Federoff H.J. Immune responses in Parkinson's disease: interplay between central and peripheral immune systems. BioMed. Res. Int. 2014, 2014:275178.
    • (2014) BioMed. Res. Int. , vol.2014 , pp. 275178
    • Su, X.1    Federoff, H.J.2
  • 130
    • 28844456921 scopus 로고    scopus 로고
    • The cytokine activity of HMGB1-extracellular escape of the nuclear protein
    • Sun N.K., Chao C.C. The cytokine activity of HMGB1-extracellular escape of the nuclear protein. Chang Gung Med. J. 2005, 28:673-682.
    • (2005) Chang Gung Med. J. , vol.28 , pp. 673-682
    • Sun, N.K.1    Chao, C.C.2
  • 131
    • 10644273486 scopus 로고    scopus 로고
    • High mobility group box protein-1 inhibits microglial abeta clearance and enhances abeta neurotoxicity
    • Takata K., Kitamura Y., Tsuchiya D., Kawasaki T., Taniguchi T., Shimohama S. High mobility group box protein-1 inhibits microglial abeta clearance and enhances abeta neurotoxicity. J. Neurosci. Res. 2004, 78:880-891.
    • (2004) J. Neurosci. Res. , vol.78 , pp. 880-891
    • Takata, K.1    Kitamura, Y.2    Tsuchiya, D.3    Kawasaki, T.4    Taniguchi, T.5    Shimohama, S.6
  • 133
    • 84865299726 scopus 로고    scopus 로고
    • PAMPs and DAMPs: signal 0s that spur autophagy and immunity
    • Tang D., Kang R., Coyne C.B., Zeh H.J., Lotze M.T. PAMPs and DAMPs: signal 0s that spur autophagy and immunity. Immunol. Rev. 2012, 249:158-175.
    • (2012) Immunol. Rev. , vol.249 , pp. 158-175
    • Tang, D.1    Kang, R.2    Coyne, C.B.3    Zeh, H.J.4    Lotze, M.T.5
  • 136
    • 84946846657 scopus 로고    scopus 로고
    • Protective effect of uric acid against 6-OHDA-induced injury in SH-SY5Y cells
    • Huang T., Gong L., Luo W., Hu L., Liu C. Protective effect of uric acid against 6-OHDA-induced injury in SH-SY5Y cells. Mol. Neurodegener. 2012, 7(Suppl 1):S12.
    • (2012) Mol. Neurodegener. , vol.7 , pp. S12
    • Huang, T.1    Gong, L.2    Luo, W.3    Hu, L.4    Liu, C.5
  • 137
    • 33745461107 scopus 로고    scopus 로고
    • High-mobility group box 1 (HMGB1) protein: friend and foe
    • Ulloa L., Messmer D. High-mobility group box 1 (HMGB1) protein: friend and foe. Cytokine Growth Factor Rev. 2006, 17:189-201.
    • (2006) Cytokine Growth Factor Rev. , vol.17 , pp. 189-201
    • Ulloa, L.1    Messmer, D.2
  • 138
    • 84871314266 scopus 로고    scopus 로고
    • Multiple binding sites on the pyrin domain of ASC protein allow self-association and interaction with NLRP3 protein
    • Vajjhala P.R., Mirams R.E., Hill J.M. Multiple binding sites on the pyrin domain of ASC protein allow self-association and interaction with NLRP3 protein. J. Biol. Chem. 2012, 287:41732-41743.
    • (2012) J. Biol. Chem. , vol.287 , pp. 41732-41743
    • Vajjhala, P.R.1    Mirams, R.E.2    Hill, J.M.3
  • 140
    • 0028102425 scopus 로고
    • S100 beta expression in Alzheimer's disease: relation to neuropathology in brain regions
    • Van Eldik L.J., Griffin W.S. S100 beta expression in Alzheimer's disease: relation to neuropathology in brain regions. Biochim. Biophys. Acta 1994, 1223:398-403.
    • (1994) Biochim. Biophys. Acta , vol.1223 , pp. 398-403
    • Van Eldik, L.J.1    Griffin, W.S.2
  • 141
    • 0142195717 scopus 로고    scopus 로고
    • The Janus face of glial-derived S100B: beneficial and detrimental functions in the brain
    • Van Eldik L.J., Wainwright M.S. The Janus face of glial-derived S100B: beneficial and detrimental functions in the brain. Restor. Neurol. Neurosci. 2003, 21:97-108.
    • (2003) Restor. Neurol. Neurosci. , vol.21 , pp. 97-108
    • Van Eldik, L.J.1    Wainwright, M.S.2
  • 143
    • 34347357758 scopus 로고    scopus 로고
    • Inflammation in Parkinson's diseases and other neurodegenerative diseases: cause and therapeutic implications
    • Wilms H., Zecca L., Rosenstiel P., Sievers J., Deuschl G., Lucius R. Inflammation in Parkinson's diseases and other neurodegenerative diseases: cause and therapeutic implications. Curr. Pharm. Des. 2007, 13:1925-1928.
    • (2007) Curr. Pharm. Des. , vol.13 , pp. 1925-1928
    • Wilms, H.1    Zecca, L.2    Rosenstiel, P.3    Sievers, J.4    Deuschl, G.5    Lucius, R.6
  • 144
    • 0029799987 scopus 로고    scopus 로고
    • Acute cognitive impairment in elderly ED patients: etiologies and outcomes
    • Wofford J.L., Loehr L.R., Schwartz E. Acute cognitive impairment in elderly ED patients: etiologies and outcomes. Am. J. Emerg. Med. 1996, 14:649-653.
    • (1996) Am. J. Emerg. Med. , vol.14 , pp. 649-653
    • Wofford, J.L.1    Loehr, L.R.2    Schwartz, E.3
  • 145
    • 84888358974 scopus 로고    scopus 로고
    • Neuron-derived IgG protects neurons from complement-dependent cytotoxicity
    • Zhang J., Niu N., Li B., McNutt M.A. Neuron-derived IgG protects neurons from complement-dependent cytotoxicity. J. Histochem. Cytochem. 2013, 61:869-879.
    • (2013) J. Histochem. Cytochem. , vol.61 , pp. 869-879
    • Zhang, J.1    Niu, N.2    Li, B.3    McNutt, M.A.4
  • 146
    • 84880183029 scopus 로고    scopus 로고
    • Neuron-derived IgG protects dopaminergic neurons from insult by 6-OHDA and activates microglia through the FcgammaR I and TLR4 pathways
    • Zhang J., Niu N., Wang M., McNutt M.A., Zhang D., Zhang B., Lu S., Liu Y., Liu Z. Neuron-derived IgG protects dopaminergic neurons from insult by 6-OHDA and activates microglia through the FcgammaR I and TLR4 pathways. Int. J. Biochem. Cell Biol. 2013, 45:1911-1920.
    • (2013) Int. J. Biochem. Cell Biol. , vol.45 , pp. 1911-1920
    • Zhang, J.1    Niu, N.2    Wang, M.3    McNutt, M.A.4    Zhang, D.5    Zhang, B.6    Lu, S.7    Liu, Y.8    Liu, Z.9
  • 147
    • 77953901974 scopus 로고    scopus 로고
    • Mitochondrial DNA is released by shock and activates neutrophils via p38 map kinase
    • Zhang Q., Itagaki K., Hauser C.J. Mitochondrial DNA is released by shock and activates neutrophils via p38 map kinase. Shock 2010, 34:55-59.
    • (2010) Shock , vol.34 , pp. 55-59
    • Zhang, Q.1    Itagaki, K.2    Hauser, C.J.3
  • 149
    • 84904102100 scopus 로고    scopus 로고
    • Editorial: skin inflammation and inflammaging
    • Zheng Q. Editorial: skin inflammation and inflammaging. Inflamm. Allergy Drug Targets 2014, 13:151-152.
    • (2014) Inflamm. Allergy Drug Targets , vol.13 , pp. 151-152
    • Zheng, Q.1
  • 150
    • 84901985008 scopus 로고    scopus 로고
    • Reactive oxygen species activated NLRP3 inflammasomes prime environment-induced murine dry eye
    • Zheng Q., Ren Y., Reinach P.S., She Y., Xiao B., Hua S., Qu J., Chen W. Reactive oxygen species activated NLRP3 inflammasomes prime environment-induced murine dry eye. Exp. Eye Res. 2014, 125C:1-8.
    • (2014) Exp. Eye Res. , vol.125C , pp. 1-8
    • Zheng, Q.1    Ren, Y.2    Reinach, P.S.3    She, Y.4    Xiao, B.5    Hua, S.6    Qu, J.7    Chen, W.8
  • 151
    • 33747890559 scopus 로고    scopus 로고
    • The brain as a target of inflammation: common pathways link inflammatory and neurodegenerative diseases
    • Zipp F., Aktas O. The brain as a target of inflammation: common pathways link inflammatory and neurodegenerative diseases. Trends Neurosci. 2006, 29:518-527.
    • (2006) Trends Neurosci. , vol.29 , pp. 518-527
    • Zipp, F.1    Aktas, O.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.