Interaction of TLR2 and TLR4 ligands with the N-terminal domain of Gp96 amplifies innate and adaptive immune responses

Journal of Biological Chemistry

Volumn 281, Issue 32, 2006, Pages 22545-22553

  Warger, Tobias ^a   Hilf, Nobert ^b   Rechtsteiner, Gerd ^a   Haselmayer, Philipp ^a   Carrick, Deanna M ^f   Jonuleit, Helmut ^c   Von Landenberg, Philipp ^d   Rammensee, Hans Georg ^e   Nicchitta, Christopher V ^f   Radsak, Markus P ^a,c   Schild, Hansjörg ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

^b IMMATICS BIOTECHNOLOGIES GMBH   (Germany)

^c UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

^d Institute for Clinical Chemistry and Laboratory Medicine   (Germany)

^e UNIVERSITY OF TÜBINGEN   (Germany)

^f DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIA; CELLS; MOLECULAR BIOLOGY; MOLECULAR STRUCTURE; POLYSACCHARIDES;

IMMUNE CELLS; LIPOPOLYSACCHARIDE CONTAMINATIONS; TLR4 LIGANDS; TOLL-LIKE RECEPTORS (TLR);

IMMUNOLOGY;

CYTOKINE; ENDOTOXIN; GLYCOPROTEIN GP 96; HEAT SHOCK PROTEIN; MARKER; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4;

ADAPTIVE BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL INFECTION; CONTROLLED STUDY; DENDRITIC CELL; GENE AMPLIFICATION; GENETIC REGULATION; HUMAN; IMMUNE RESPONSE; INCUBATION TIME; INNATE IMMUNITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN INTERACTION; T LYMPHOCYTE ACTIVATION;

ANIMALS; CD8-POSITIVE T-LYMPHOCYTES; DOGS; ENDOTOXINS; HUMANS; INFLAMMATION; LIPOPOLYSACCHARIDES; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 4;

BACTERIA (MICROORGANISMS); NEGIBACTERIA;

EID: 33747339222     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M502900200     Document Type: Article

References (53)

1. Parsell, D. A., and Lindquist, S. (1993) Annu. Rev. Genet. 27, 437-496
2. Gething, M. J., and Sambrook, J. (1992) Nature 355, 33-45
3. Schild, H., Arnold-Schild, D., Lammert, E., and Rammensee, H. G. (1999) Curr. Opin. Immunol. 11, 109-113
4. Srivastava, P. (2002) Nat. Rev. Immunol. 2, 185-194
5. Bevan, M. J. (1976) J. Exp. Med. 143, 1283-1288
6. Arnold, D., Faath, S., Rammensee, H., and Schild, H. (1995) J. Exp. Med. 182, 885-889
7. Arnold-Schild, D., Hanau, D., Spehner, D., Schmid, C., Rammensee, H. G., de la Salle, H., and Schild, H. (1999) J. Immunol. 162, 3757-3760
8. Singh-Jasuja, H., Toes, R. E., Spee, P., Munz, C., Hilf, N., Schoenberger, S. P., Ricciardi-Castagnoli, P., Neefjes, J., Rammensee, H. G., Arnold-Schild, D., and Schild, H. (2000) J. Exp. Med. 191, 1965-1974
9. Castellino, F., Boucher, P. E., Eichelberg, K., Mayhew, M., Rothman, J. E., Houghton, A. N., and Germain, R. N. (2000) J. Exp. Med. 191, 1957-1964
10. Berwin, B., Hart, J. P., Rice, S., Gass, C., Pizzo, S. V., Post, S. R., and Nicchitta, C. V. (2003) EMBO J. 22, 6127-6136
11. Binder, R. J., Han, D. K., and Srivastava, P. K. (2000) Nat. Immunol. 1, 151-155
12. Basu, S., Binder, R. J., Ramalingam, T., and Srivastava, P. K. (2001) Immunity 14, 303-313
13. Delneste, Y., Magistrelli, G., Gauchat, J., Haeuw, J., Aubry, J., Nakamura, K., Kawakami-Honda, N., Goetsch, L., Sawamura, T., Bonnefoy, J., and Jeannin, P. (2002) Immunity 17, 353-362
14. Panjwani, N. N., Popova, L., and Srivastava, P. K. (2002) J. Immunol. 168, 2997-3003
15. Wang, Y., Kelly, C. G., Karttunen, J. T., Whittall, T., Lehner, P. J., Duncan, L., MacAry, P., Younson, J. S., Singh, M., Oehlmann, W., Cheng, G., Bergmeier, L., and Lehner, T. (2001) Immunity 15, 971-983
16. Singh-Jasuja, H., Scherer, H. U., Hilf, N., Arnold-Schild, D., Rammensee, H. G., Toes, R. E. M., and Schild, H. (2000) Eur. J. Immunol. 30, 2211-2215
17. Basu, S., Binder, R. J., Suto, R., Anderson, K. M., and Srivastava, P. K. (2000) Int. Immunol. 12, 1539-1546
18. Binder, R. J., Anderson, K. M., Basu, S., and Srivastava, P. K. (2000) J. Immunol. 165, 6029-6035
19. Ohashi, K., Burkart, V., Flohe, S., and Kolb, H. (2000) J. Immunol. 164, 558-561
20. Asea, A., Kraeft, S. K., Kurt-Jones, E. A., Stevenson, M. A., Chen, L. B., Finberg, R. W., Koo, G. C., and Calderwood, S. K. (2000) Nat. Med. 6, 435-442
21. Vabulas, R. M., Braedel, S., Hilf, N., Singh-Jasuja, H., Herter, S., Ahmad-Nejad, P., Kirschning, C. J., Da Costa, C., Rammensee, H. G., Wagner, H., and Schild, H. (2002) J. Biol. Chem. 277, 20847-20853
22. Vabulas, R. M., Ahmad-Nejad, P., Ghose, S., Kirschning, C. J., Issels, R. D., and Wagner, H. (2002) J. Biol. Chem. 277, 15107-15112
23. Asea, A., Rehli, M., Kabingu, E., Boch, J. A., Bare, O., Auron, P. E., Stevenson, M. A., and Calderwood, S. K. (2002) J. Biol. Chem. 277, 15028-15034
24. Wallin, R. P., Lundqvist, A., More, S. H., von Bonin, A., Kiessling, R., and Ljunggren, H. G. (2002) Trends Immunol. 23, 130-135
25. Flohe, S. B., Bruggemann, J., Lendemans, S., Nikulina, M., Meierhoff, G., Flohe, S., and Kolb, H. (2003) J. Immunol. 170, 2340-2348
26. Gao, B., and Tsan, M. F. (2003) J. Biol. Chem. 278, 22523-22529
27. Gao, B., and Tsan, M. F. (2003) J. Biol. Chem. 278, 174-179
28. Reed, R. C., Berwin, B., Baker, J. P., and Nicchitta, C. V. (2003) J. Biol. Chem. 278, 31853-31860
29. Radsak, M. P., Hilf, N., Singh-Jasuja, H., Braedel, S., Brossart, P., Rammensee, H. G., and Schild, H. (2003) Blood 101, 2810-2815
30. Takakuwa, T., Knopf, H. P., Sing, A., Carsetti, R., Galanos, C., and Freudenberg, M. A. (1996) Eur. J. Immunol. 26, 2686-2692
31. Inaba, K., Inaba, M., Romani, N., Aya, H., Deguchi, M., Ikehara, S., Muramatsu, S., and Steinman, R. M. (1992) J. Exp. Med. 176, 1693-1702
32. Randow, F., and Seed, B. (2001) Nat. Cell Biol. 3, 891-896
33. Aliprantis, A. O., Yang, R. B., Mark, M. R., Suggett, S., Devaux, B., Radolf, J. D., Klimpel, G. R., Godowski, P., and Zychlinsky, A. (1999) Science 285, 736-739
34. Schild, H., and Rammensee, H. G. (2000) Nat. Immunol. 1, 100-101
35. Seong, S. Y., and Matzinger, P. (2004) Nat. Rev. Immunol. 4, 469-478
36. Bausinger, H., Lipsker, D., Ziylan, U., Manie, S., Briand, J. P., Cazenave, J. P., Muller, S., Haeuw, J. F., Ravanat, C., de la, S. H., and Hanau, D. (2002) Eur. J. Immunol. 32, 3708-3713
37. Tsan, M. F., and Gao, B. (2004) Am. J. Physiol. 286, C739-C744
38. Hornef, M. W., Normark, B. H., Vandewalle, A., and Normark, S. (2003) J. Exp. Med. 198, 1225-1235
39. Shimazu, R., Akashi, S., Ogata, H., Nagai, Y., Fukudome, K., Miyake, K., and Kimoto, M. (1999) J. Exp. Med. 189, 1777-1782
40. Triantafilou, K., Triantafilou, M., and Dedrick, R. L. (2001) Nat. Immunol. 2, 338-345
41. Machnicki, M., Zimecki, M., and Zagulski, T. (1993) Int. J. Exp. Pathol. 74, 433-439
42. Kaca, W., Roth, R. I., and Levin, J. (1994) J. Biol. Chem. 269, 25078-25084
43. Gorczynski, R. M., Alexander, C., Bessler, W., Fournier, K., Hoffmann, P., Mach, J. P., Manuel, J., Ramakrishna, V., Rietschel, E. T., Song, L., Waelli, T., Westphal, O., and Zahringer, U. (2004) Int. Immunopharmacol. 4, 1859-1872
44. Baker-LePain, J. C., Sarzotti, M., and Nicchitta, C. V. (2004) J. Immunol. 172, 4195-4203
45. Wan, T., Zhou, X., Chen, G., An, H., Chen, T., Zhang, W., Liu, S., Jiang, Y., Yang, F., Wu, Y., and Cao, X. (2004) Blood 103, 1747-1754
46. Zheng, H., Dai, J., Stoilova, D., and Li, Z. (2001) J. Immunol. 167, 6731-6735
47. Baker-LePain, J. C., Sarzotti, M., Fields, T. A., Li, C. Y., and Nicchitta, C. V. (2002) J. Exp. Med. 196, 1447-1459
48. Liu, B., Dai, J., Zheng, H., Stoilova, D., Sun, S., and Li, Z. (2003) Proc. Natl. Acad. Sci. U. S. A. 100, 15824-15829
49. Shi, Y., Evans, J. E., and Rock, K. L. (2003) Nature 425, 516-521
50. Johnson, G. B., Brunn, G. J., Kodaira, Y., and Platt, J. L. (2002) J. Immunol. 168, 5233-5239
51. Janeway, C. A., Jr. (1992) Immunol. Today 13, 11-16
52. Matzinger, P. (1994) Annu. Rev. Immunol. 12, 991-1045
53. Soldano, K. L., Jivan, A., Nicchitta, C. V., and Gewirth, T. (2003) J. Biol. Chem. 278, 48330-48338