Mitochondrial DNA is released by shock and activates neutrophils via P38 map kinase

Shock

Volumn 34, Issue 1, 2010, Pages 55-59

  Zhang, Qin ^a   Itagaki, Kiyoshi ^a   Hauser, Carl J ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

DAMPs; MAPK; mitochondria; neutrophils; toll like receptors; Trauma hemorrhagic shock

Indexed keywords

CELL NUCLEUS DNA; CHLOROQUINE; GELATINASE B; INTERLEUKIN 6; MITOCHONDRIAL DNA; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; NEUTROPHIL COLLAGENASE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CIRCULATION; CONTROLLED STUDY; DNA PURIFICATION; ENZYME RELEASE; HEMORRHAGIC SHOCK; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; INCUBATION TEMPERATURE; LEUKOCYTE ACTIVATION; LIVER; MALE; NONHUMAN; PHENOTYPE; PROTEIN PHOSPHORYLATION; RAT; SHOCK; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME;

ANIMALS; BLOTTING, WESTERN; DNA, MITOCHONDRIAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; INTERLEUKIN-6; MALE; MATRIX METALLOPROTEINASE 8; MATRIX METALLOPROTEINASE 9; NEUTROPHILS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; POLYMERASE CHAIN REACTION; RATS; RATS, SPRAGUE-DAWLEY; SHOCK; TUMOR NECROSIS FACTOR-ALPHA;

EID: 77953901974     PISSN: 10732322     EISSN: None     Source Type: Journal    
DOI: 10.1097/SHK.0b013e3181cd8c08     Document Type: Article

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