|
|
Volumn 106, Issue , 2015, Pages 60-74
|
|
Novel oxime-bearing coumarin derivatives act as potent Nrf2/ARE activators in vitro and in mouse model
a
b,c
d
d
b
a
a
b
b
b,e
b
b,e,f
|
|
Author keywords
Antioxidant activity; Cytoprotection; Nrf2 ARE activators; Oxime bearing coumarins
|
|
Indexed keywords
3 (2 OXO 2 PHENYLETHOXY) 2H CHROMEN 2 ONE;
3 HYDROXYCOUMARIN;
3 [2 (4 FLUOROPHENYL) 2 (HYDROXYIMINO)ETHOXY] 2H CHROMEN 2 ONE;
3 [2 (BIPHENYL 4 YL) 2 (HYDROXYIMINO)ETHOXY] 2H CHROMEN 2 ONE;
3 [2 (HYDROXYIMINO) 2 (4 METHOXYPHENYL)ETHOXY] 2H CHROMEN 2 ONE;
3 [2 (HYDROXYIMINO) 2 PHENYLETHOXY] 2H CHROMEN 2 ONE;
3 [2 (HYDROXYIMINO)PROPOXY] 2H CHROMEN 2 ONE;
3 [2 (NAPHTHALEN 2 YL) 2 OXOETHOXY] 2H CHROMEN 2 ONE;
4 [2 (4 FLUOROPHENYL) 2 (HYDROXYIMINO)ETHOXY] 2H CHROMEN 2 ONE;
4 [2 (BIPHENYL 4 YL) 2 (HYDROXYIMINO)ETHOXY] 2H CHROMEN 2 ONE;
4 [2 (HYDROXYIMINO) 2 (4 METHOXYPHENYL)ETHOXY] 2H CHROMEN 2 ONE;
4 [2 (HYDROXYIMINO) 2 (NAPHTHALENE 2 YL)ETHOXY] 2H CHROMEN 2 ONE;
4 [2 (HYDROXYIMINO) 2 PHENYLETHOXY] 2H CHROMEN 2 ONE;
4 [2 (HYDROXYIMINO)PROPOXY] 2H CHROMEN 2 ONE;
4 [2 (NAPHTHALEN 2 YL) 2 OXOETHOXY] 2H CHROMEN 2 ONE;
6 [2 (HYDROXYIMINO)PROPOXY] 2H CHROMEN 2 ONE;
6 [2 (NAPHTHALEN 2 YL) 2 OXOETHOXY] 2H CHROMEN 2 ONE;
7 [2 (HYDROXYIMINO)PROPOXY] 2H CHROMEN 2 ONE;
ALDO KETO REDUCTASE 1 SUBUNIT C 1;
ANTIOXIDANT;
BUTYLCRESOL;
COUMARIN DERIVATIVE;
CYTOPROTECTIVE AGENT;
GLUTATHIONE REDUCTASE;
HEME OXYGENASE 1;
MESSENGER RNA;
PROTEIN;
PROTEIN KINASE C;
TRANSCRIPTION FACTOR NRF2;
UNCLASSIFIED DRUG;
UNINDEXED DRUG;
COUMARIN;
LUCIFERASE;
OXIME;
ALKYLATION;
ANIMAL EXPERIMENT;
ANTIOXIDANT ACTIVITY;
ANTIOXIDANT RESPONSIVE ELEMENT;
ARTICLE;
DRUG POTENCY;
HSC 3 CELL LINE;
IN VITRO STUDY;
MOUSE;
NONHUMAN;
OXIDATIVE STRESS;
PROTEIN EXPRESSION;
PROTEIN PHOSPHORYLATION;
AGONISTS;
ANIMAL;
ANIMAL MODEL;
BIOSYNTHESIS;
C57BL MOUSE;
CELL SURVIVAL;
CHEMICAL STRUCTURE;
CHEMISTRY;
DOSE RESPONSE;
DRUG EFFECTS;
GENETICS;
HUMAN;
MALE;
METABOLISM;
STRUCTURE ACTIVITY RELATION;
TUMOR CELL CULTURE;
ANIMALS;
ANTIOXIDANT RESPONSE ELEMENTS;
CELL SURVIVAL;
COUMARINS;
DOSE-RESPONSE RELATIONSHIP, DRUG;
HUMANS;
IN VITRO TECHNIQUES;
LUCIFERASES;
MALE;
MICE;
MICE, INBRED C57BL;
MODELS, ANIMAL;
MOLECULAR STRUCTURE;
NF-E2-RELATED FACTOR 2;
OXIDATIVE STRESS;
OXIMES;
STRUCTURE-ACTIVITY RELATIONSHIP;
TUMOR CELLS, CULTURED;
|
|
EID: 84946830412
PISSN: 02235234
EISSN: 17683254
Source Type: Journal
DOI: 10.1016/j.ejmech.2015.10.029 Document Type: Article |
|
Times cited : (16)
|
|
References (50)
|
