Discovery of vinyl sulfones as a novel class of neuroprotective agents toward Parkinson's disease therapy

Journal of Medicinal Chemistry

Volumn 57, Issue 4, 2014, Pages 1473-1487

  Woo, Seo Yeon ^a   Kim, Ji Hyun ^c   Moon, Mi Kyeong ^c   Han, Se Hee ^c   Yeon, Seul Ki ^a   Choi, Ji Won ^a   Jang, Bo Ko ^a   Song, Hyo Jung ^a   Kang, Yong Gu ^a   Kim, Jin Woo ^a   Lee, Jaeick ^b   Kim, Dong Jin ^a   Hwang, Onyou ^c   Park, Ki Duk ^a  

^a Brain Science Institute   (South Korea)

^b Korea Institute of Science and Technology   (South Korea)

^c University of Ulsan College of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME; GCLC ENZYME; GLCM ENZYME; HO 1 ENZYME; NEUROPROTECTIVE AGENT; NQO1 ENZYME; SULFONE DERIVATIVE; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG; VINYL SULFONE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; HUMAN; HUMAN CELL; MALE; MOUSE; NONHUMAN; PARKINSON DISEASE;

ANIMALS; BASE SEQUENCE; CELL LINE; DISEASE MODELS, ANIMAL; DNA PRIMERS; HEME OXYGENASE-1; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; PARKINSON DISEASE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SULFONES;

EID: 84896873605     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm401788m     Document Type: Article

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