Chemoprotective properties of phenylpropenoids, bis(benzylidene)cycloalkanones, and related Michael reaction acceptors: Correlation of potencies as phase 2 enzyme inducers and radical scavengers

Journal of Medicinal Chemistry

Volumn 41, Issue 26, 1998, Pages 5287-5296

  Dinkova Kostova, Albena T ^a   Abeygunawardana, Chitrananda ^a   Talalay, Paul ^b  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHALCONE DERIVATIVE; CINNAMIC ACID DERIVATIVE; COUMARIC ACID; ENZYME INDUCING AGENT; FERULIC ACID; SCAVENGER; SINAPIC ACID DERIVATIVE;

ANIMAL CELL; ARTICLE; CANCER CELL CULTURE; CHEMOPROPHYLAXIS; DRUG ACTIVITY; DRUG MECHANISM; DRUG POTENCY; DRUG SCREENING; DRUG STRUCTURE; ENZYME INDUCTION; MOUSE; NONHUMAN; SCAVENGING SYSTEM;

ANIMALS; ANTICARCINOGENIC AGENTS; CHALCONE; CHEMILUMINESCENT MEASUREMENTS; CINNAMATES; COUMARINS; ENZYME INDUCTION; FREE RADICAL SCAVENGERS; LIVER NEOPLASMS, EXPERIMENTAL; MAGNETIC RESONANCE SPECTROSCOPY; MICE; MOLECULAR CONFORMATION; NAD(P)H DEHYDROGENASE (QUINONE); STRUCTURE-ACTIVITY RELATIONSHIP; SUPEROXIDES; TUMOR CELLS, CULTURED;

EID: 0032542331     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm980424s     Document Type: Article

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