Design, synthesis and anticancer activities of stilbene-coumarin hybrid compounds: Identification of novel proapoptotic agents

Bioorganic and Medicinal Chemistry

Volumn 18, Issue 10, 2010, Pages 3543-3550

  Belluti, Federica ^a   Fontana, Gabriele ^b   Bo, Laura Dal ^c   Carenini, Nives ^c   Giommarelli, Chiara ^c   Zunino, Franco ^c  

^a Dipartimento di Scienze Farmaceutiche   (Italy)

^b INDENA S P A   (Italy)

^c NATIONAL CANCER INSTITUTE   (Italy)

Author keywords

Antitumor; Apoptosis; Coumarins; Hybrid compound; Resveratrol

Indexed keywords

3 [2 (3,5 DIMETHOXYPHENYL)VINYL] 7 METHOXY 2H CHROMEN 2 ONE; 4 [2 (3,5 DIMETHOXYPHENYL)ETHYL] 7 METHOXY 2H CHROMEN 2 ONE; 4 [2 (3,5 DIMETHOXYPHENYL)VINYL] 2H CHROMEN 2 ONE; 4 [2 (3,5 DIMETHOXYPHENYL)VINYL] 6 METHOXY 2H CHROMEN 2 ONE; 4 [2 (3,5 DIMETHOXYPHENYL)VINYL] 7 HYDROXYCHROMEN 2H 2 ONE; 7 METHOXY 4 [2 (2,3,4 TRIMETHOXYPHENYL)VINYL] 2H CHROMEN 2 ONE; 7 METHOXY 4 [2 (3 METHOXYPHENYL)VINYL] 2H CHROMEN 2 ONE; 7 METHOXY 4 [2 (3,4,5 TRIMETHOXYPHENYL)VINYL] 2H CHROMEN 2 ONE; 7 METHOXY 4 [2 (3,5 DIMETHOXYPHENYL)VINYL] 2H CHROMEN 2 ONE; 7 METHOXY 4 [[2 (3 METHYLBUT 2 ENYLOXY)PHENYL]VINYL] 2H CHROMEN 2 ONE; ANTINEOPLASTIC AGENT; CASPASE 3; COUMARIN DERIVATIVE; RESVERATROL; STILBENE DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; LUNG CARCINOMA; PROTON NUCLEAR MAGNETIC RESONANCE;

EID: 77953134777     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2010.03.069     Document Type: Article

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