Caffeine impairs resection during DNA break repair by reducing the levels of nucleases Sae2 and Dna2

Nucleic Acids Research

Volumn 43, Issue 14, 2015, Pages 6889-6901

  Tsabar, Michael ^a   Eapen, Vinay V ^a   Mason, Jennifer M ^b   Memisoglu, Gonen ^a   Waterman, David P ^a   Long, Marcus J ^a,c   Bishop, Douglas K ^b   Haber, James E ^a  

^a BRANDEIS UNIVERSITY   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

^c Department of Chemistry and Chemical Biology Cornell University ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CAFFEINE; CYCLOHEXIMIDE; HISTONE H2AX; NUCLEASE; PROTEASOME; PROTEIN DNA2; PROTEIN KINASE; PROTEIN MEC1; PROTEIN SAE2; PROTEIN TEL1; RAD51 PROTEIN; REPLICATION FACTOR A; UNCLASSIFIED DRUG; DNA HELICASE; DNA2 PROTEIN, S CEREVISIAE; ENDONUCLEASE; HISTONE; MEC1 PROTEIN, S CEREVISIAE; PROTEIN SERINE THREONINE KINASE; SACCHAROMYCES CEREVISIAE PROTEIN; SAE2 PROTEIN, S CEREVISIAE; SIGNAL PEPTIDE; TEL1 PROTEIN, S CEREVISIAE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DNA DAMAGE CHECKPOINT; DNA REPAIR; DOUBLE STRANDED DNA BREAK; ENZYMATIC DEGRADATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GENE LOCUS; HALF LIFE TIME; HOMOLOGOUS RECOMBINATION; MAMMAL CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; ANTAGONISTS AND INHIBITORS; DRUG EFFECTS; ENZYMOLOGY; GENETICS; HELA CELL LINE; HUMAN; METABOLISM; SACCHAROMYCES CEREVISIAE;

CAFFEINE; DNA BREAKS, DOUBLE-STRANDED; DNA HELICASES; DNA REPAIR; ENDONUCLEASES; HELA CELLS; HISTONES; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN-SERINE-THREONINE KINASES; RAD51 RECOMBINASE; REPLICATION PROTEIN A; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

EID: 84944937940     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkv520     Document Type: Article

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