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Volumn 279, Issue , 2003, Pages 73-84

Autophagy in yeast: A TOR-mediated response to nutrient starvation

Author keywords

[No Author keywords available]

Indexed keywords

APG1 PROTEIN; APG13 PROTEIN; APG8 PROTEIN; AUT7 PROTEIN; CYCLIN DEPENDENT KINASE; CYCLOHEXIMIDE; FUNGAL PROTEIN; GCN2 PROTEIN KINASE; GCN4 PROTEIN KINASE; GENE PRODUCT; GLN3 PROTEIN; GLYCOGEN; GUANOSINE TRIPHOSPHATASE; PHO85 PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN; RAPAMYCIN; SNF1 PROTEIN KINASE; TAP42 PROTEIN; TARGET OF RAPAMYCIN KINASE; UNCLASSIFIED DRUG; URE2 PROTEIN;

EID: 0042322394     PISSN: 0070217X     EISSN: None     Source Type: Book Series    
DOI: None     Document Type: Review
Times cited : (171)

References (45)
  • 1
    • 0033231275 scopus 로고    scopus 로고
    • Cytoplasm to vacuole trafficking of amino-peptidase I requires a t-SNARE-Sec1p complex composed of Tlg2p and Vps45p
    • Abeliovich H, Darsow T, Emr SD (1999) Cytoplasm to vacuole trafficking of amino-peptidase I requires a t-SNARE-Sec1p complex composed of Tlg2p and Vps45p. EMBO J. 18:6005-6016
    • (1999) EMBO J , vol.18 , pp. 6005-6016
    • Abeliovich, H.1    Darsow, T.2    Emr, S.D.3
  • 2
    • 0034722378 scopus 로고    scopus 로고
    • Dissection of autophagosome biogenesis into distinct nucleation and expansion steps
    • Abeliovich H, Dunn Jr. WA, Kim J, Klionsky DJ (2000) Dissection of autophagosome biogenesis into distinct nucleation and expansion steps. J. Cell Biol. 151:1025-1033
    • (2000) J Cell Biol , vol.151 , pp. 1025-1033
    • Abeliovich, H.1    Dunn W.A., Jr.2    Kim, J.3    Klionsky, D.J.4
  • 3
    • 0028230738 scopus 로고
    • Ultrastructural analysis of the autophagic process in yeast: Detection of autophagosomes and their characterization
    • Baba M, Takeshige K, Baba N, Ohsumi Y (1994) Ultrastructural analysis of the autophagic process in yeast: detection of autophagosomes and their characterization. J. Cell Biol. 124:903-913
    • (1994) J Cell Biol , vol.124 , pp. 903-913
    • Baba, M.1    Takeshige, K.2    Baba, N.3    Ohsumi, Y.4
  • 4
    • 0031417385 scopus 로고    scopus 로고
    • Two distinct pathways for targeting proteins from the cytoplasm to the vacuole/lysosome
    • Baba M, Ohsumi M, Scott SV, Klionsky DJ, Ohsumi Y (1997) Two distinct pathways for targeting proteins from the cytoplasm to the vacuole/lysosome. J Cell Biol. 139:1687-1695
    • (1997) J Cell Biol , vol.139 , pp. 1687-1695
    • Baba, M.1    Ohsumi, M.2    Scott, S.V.3    Klionsky, D.J.4    Ohsumi, Y.5
  • 6
    • 0033588918 scopus 로고    scopus 로고
    • Starvation induces vacuolar targeting and degradation of the tryptophan permease in yeast
    • Beck T, Schmidt A, Hall MN (1999) Starvation induces vacuolar targeting and degradation of the tryptophan permease in yeast. J Cell Biol. 146:1227-1238
    • (1999) J Cell Biol , vol.146 , pp. 1227-1238
    • Beck, T.1    Schmidt, A.2    Hall, M.N.3
  • 7
    • 0033540030 scopus 로고    scopus 로고
    • The TOR signalling pathway controls nuclear localization of nutrient-regulated transcription factors
    • Beck T, Hall MN. 1999. The TOR signalling pathway controls nuclear localization of nutrient-regulated transcription factors. Nature. 402:689-692
    • (1999) Nature , vol.402 , pp. 689-692
    • Beck, T.1    Hall, M.N.2
  • 9
    • 0033573016 scopus 로고    scopus 로고
    • The TOR signaling cascade regulates gene expression in response to nutrients
    • Cardenas ME, Cutler NS, Lorenz MC, Di Como CJ, Heitman J (1999) The TOR signaling cascade regulates gene expression in response to nutrients. Genes Dev. 13, 3271-3279
    • (1999) Genes Dev , vol.13 , pp. 3271-3279
    • Cardenas, M.E.1    Cutler, N.S.2    Lorenz, M.C.3    Di Como, C.J.4    Heitman, J.5
  • 10
    • 0035794172 scopus 로고    scopus 로고
    • Regulation of Apg14 expression by the GATA-type transcription factor Gln3p
    • Chan TF, Bertram PG, Ai W, Zheng XFS (2001) Regulation of Apg14 expression by the GATA-type transcription factor Gln3p. J. Biol. Chem. 276:6463-6467
    • (2001) J Biol Chem , vol.276 , pp. 6463-6467
    • Chan, T.F.1    Bertram, P.G.2    Ai, W.3    Zheng, X.F.S.4
  • 11
    • 0029808294 scopus 로고    scopus 로고
    • Nutrients, via the TOR proteins, stimulate the association of Tap42 with type 2A phosphatases
    • Di Como CJ, Arndt KT (1996) Nutrients, via the TOR proteins, stimulate the association of Tap42 with type 2A phosphatases. Genes Dev. 10:1904-1916
    • (1996) Genes Dev , vol.10 , pp. 1904-1916
    • Di Como, C.J.1    Arndt, K.T.2
  • 12
    • 0030919092 scopus 로고    scopus 로고
    • Analyses of APG13 gene involved in autophagy in yeast, Saccharomyces cerevisiae
    • Funakoshi T, Matsuura A, Noda T, Ohsumi Y (1997) Analyses of APG13 gene involved in autophagy in yeast, Saccharomyces cerevisiae. Gene 192:207-13
    • (1997) Gene , vol.192 , pp. 207-213
    • Funakoshi, T.1    Matsuura, A.2    Noda, T.3    Ohsumi, Y.4
  • 13
    • 0033592983 scopus 로고    scopus 로고
    • Rapamycin-modulated transcription defines the subset of nutrient-sensitive signaling pathways directly controlled by the TOR proteins
    • Hardwick J, Kuruvilla FG, Tong JK, Shamji AF, Schreiber SL. (1999) Rapamycin-modulated transcription defines the subset of nutrient-sensitive signaling pathways directly controlled by the TOR proteins. Proc. Natl. Acad. Sci. U S A. 96:14866-14870
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 14866-14870
    • Hardwick, J.1    Kuruvilla, F.G.2    Tong, J.K.3    Shamji, A.F.4    Schreiber, S.L.5
  • 14
    • 0001634436 scopus 로고
    • General and pathway-specific regulatory mechanisms controlling the synthesis of amino acid biosynthetic enzymes in Saccharomyces cerevisiae
    • Jones EW, Pringle JR, Broach JR (eds). Cold Spring Harbor Laboratory Press
    • Hinnebusch AG (1992) General and pathway-specific regulatory mechanisms controlling the synthesis of amino acid biosynthetic enzymes in Saccharomyces cerevisiae. In: Jones EW, Pringle JR, Broach JR (eds) The molecular and cellular biology of the yeast Saccharomyces vol. 2. Cold Spring Harbor Laboratory Press, pp 319-414
    • (1992) The Molecular and Cellular Biology of the Yeast Saccharomyces , vol.2 , pp. 319-414
    • Hinnebusch, A.G.1
  • 15
    • 0029954396 scopus 로고    scopus 로고
    • Pho85p, a cyclin-dependent protein kinase, and the Snflp protein kinase act antagonistically to control glycogen accumulation in Saccharomyces cerevisiae
    • Huang D, Farkas I, Roach PJ (1996) Pho85p, a cyclin-dependent protein kinase, and the Snflp protein kinase act antagonistically to control glycogen accumulation in Saccharomyces cerevisiae. Mol. Cell. Biol. 16:4357-4365
    • (1996) Mol Cell Biol , vol.16 , pp. 4357-4365
    • Huang, D.1    Farkas, I.2    Roach, P.J.3
  • 16
    • 0035827541 scopus 로고    scopus 로고
    • Vacuolar localization of oligomeric α-mannosidase requires the cytoplasm to vacuole targeting and autophagy pathway components in Saccharomyces cerevisiae
    • 2001
    • Hutchins U, Klionsky DJ (2001) Vacuolar localization of oligomeric α-mannosidase requires the cytoplasm to vacuole targeting and autophagy pathway components in Saccharomyces cerevisiae. J. Biol. Chem. 2001 276:20491-20498
    • (2001) J Biol Chem , vol.276 , pp. 20491-20498
    • Hutchins, U.1    Klionsky, D.J.2
  • 19
    • 0033577745 scopus 로고    scopus 로고
    • TOR proteins and protein phosphatase 2A reciprocally regulated Tap42 in controlling cell growth in yeast
    • Jiang Y, Broach J (1999) TOR proteins and protein phosphatase 2A reciprocally regulated Tap42 in controlling cell growth in yeast. EMBO J. 18, 2782-2792
    • (1999) EMBO J , vol.18 , pp. 2782-2792
    • Jiang, Y.1    Broach, J.2
  • 20
    • 0000632439 scopus 로고
    • Regulation of carbon and phosphate utilization
    • Jones EW, Pringle JR, Broach JR (eds). Cold Spring Harbor Laboratory Press
    • Johnston M, Carlson M (1992) Regulation of carbon and phosphate utilization. In: Jones EW, Pringle JR, Broach JR (eds) The molecular and cellular biology of the yeast Saccharomyces vol. 2. Cold Spring Harbor Laboratory Press, pp 193-281
    • (1992) The Molecular and Cellular Biology of the Yeast Saccharomyces , vol.2 , pp. 193-281
    • Johnston, M.1    Carlson, M.2
  • 22
    • 0032575551 scopus 로고    scopus 로고
    • Apg14p and Apg6/Vps30p form a protein complex essential for autophagy in the yeast. Saccharomyces cerevisiae
    • Kametaka S, Okano T, Ohsumi M, Ohsumi Y (1998) Apg14p and Apg6/Vps30p form a protein complex essential for autophagy in the yeast, Saccharomyces cerevisiae. J. Biol. Chem. 273:22284-22291
    • (1998) J Biol Chem , vol.273 , pp. 22284-22291
    • Kametaka, S.1    Okano, T.2    Ohsumi, M.3    Ohsumi, Y.4
  • 23
    • 0035809160 scopus 로고    scopus 로고
    • Two distinct Vps34 phosphatidylinositol 3-kinase complex function in autophagy and carboxypeptidase Y sorting in Saccharomyces cerevisiae
    • Kihara A, Noda T, Ishihara N, Ohsumi Y (2001) Two distinct Vps34 phosphatidylinositol 3-kinase complex function in autophagy and carboxypeptidase Y sorting in Saccharomyces cerevisiae. J. Cell Biol. 152:519-530
    • (2001) J Cell Biol , vol.152 , pp. 519-530
    • Kihara, A.1    Noda, T.2    Ishihara, N.3    Ohsumi, Y.4
  • 26
    • 0034676037 scopus 로고    scopus 로고
    • The reversible modification regulates the membrane-binding state of Apg8/Aut7 essential for autophagy and the cytoplasm to vacuole targeting pathway
    • Kirisako T, Ichimura Y, Okada H, Kabeya Y, Mizushima N, Yoshimori T, Ohsumi M, Takao T, Noda T, Ohsumi Y (2000) The reversible modification regulates the membrane-binding state of Apg8/Aut7 essential for autophagy and the cytoplasm to vacuole targeting pathway. J. Cell Biol. 151:263-275
    • (2000) J Cell Biol , vol.151 , pp. 263-275
    • Kirisako, T.1    Ichimura, Y.2    Okada, H.3    Kabeya, Y.4    Mizushima, N.5    Yoshimori, T.6    Ohsumi, M.7    Takao, T.8    Noda, T.9    Ohsumi, Y.10
  • 27
    • 0032079372 scopus 로고    scopus 로고
    • Nonclassical protein sorting to the yeast vacuole
    • Klionsky DJ (1998) Nonclassical protein sorting to the yeast vacuole. J. Biol. Chem. 273:10807-10810
    • (1998) J Biol Chem , vol.273 , pp. 10807-10810
    • Klionsky, D.J.1
  • 28
    • 0033280667 scopus 로고    scopus 로고
    • Vacuolar import of proteins and organelles from the cytoplasm
    • Klionsky DJ, Ohsumi Y (1999) Vacuolar import of proteins and organelles from the cytoplasm. Annu. Rev. Cell. Dev. Biol. 15:1-32
    • (1999) Annu Rev Cell Dev Biol , vol.15 , pp. 1-32
    • Klionsky, D.J.1    Ohsumi, Y.2
  • 29
    • 0032126632 scopus 로고    scopus 로고
    • Aut2p and Aut7p, two novel microtubule-associated proteins are essential for delivery of autophagic vesicles to the vacuole
    • Lang T, Schaeffeler E, Bernreuther D, Bredschneider M, Wolf DH Thumm M (1998) Aut2p and Aut7p, two novel microtubule-associated proteins are essential for delivery of autophagic vesicles to the vacuole. EMBO J. 17:3597-3607
    • (1998) EMBO J , vol.17 , pp. 3597-3607
    • Lang, T.1    Schaeffeler, E.2    Bernreuther, D.3    Bredschneider, M.4    Wolf, D.H.5    Thumm, M.6
  • 30
    • 0000025835 scopus 로고
    • Regulation of nitrogen utilization
    • Jones EW, Pringle JR, Broach JR (eds). Cold Spring Harbor Laboratory Press
    • Magasanik B (1992) Regulation of nitrogen utilization. In: Jones EW, Pringle JR, Broach JR (eds) The molecular and cellular biology of the yeast Saccharomyces vol. 2. Cold Spring Harbor Laboratory Press, pp 283-317
    • (1992) The Molecular and Cellular Biology of the Yeast Saccharomyces , vol.2 , pp. 283-317
    • Magasanik, B.1
  • 31
    • 0030983504 scopus 로고    scopus 로고
    • Apg1p, a novel protein kinase required for the autophagic process in Saccharomyces cerevisiae
    • Matsuura A, Tsukada M, Wada Y, Ohsumi Y (1997) Apg1p, a novel protein kinase required for the autophagic process in Saccharomyces cerevisiae. Gene 192:245-250
    • (1997) Gene , vol.192 , pp. 245-250
    • Matsuura, A.1    Tsukada, M.2    Wada, Y.3    Ohsumi, Y.4
  • 33
    • 0034973590 scopus 로고    scopus 로고
    • Transcriptional profiling shows that Gcn4p is a master regulator of gene expression during amino acid starvation in yeast
    • Natarajan K, Meyer MR, Jackson BM, Slade D, Roberts C, Hinnebusch AG, Marton MJ (2001) Transcriptional profiling shows that Gcn4p is a master regulator of gene expression during amino acid starvation in yeast. Mol. Cell. Biol. 21:4347-4368
    • (2001) Mol Cell Biol , vol.21 , pp. 4347-4368
    • Natarajan, K.1    Meyer, M.R.2    Jackson, B.M.3    Slade, D.4    Roberts, C.5    Hinnebusch, A.G.6    Marton, M.J.7
  • 34
    • 0029036915 scopus 로고
    • Novel system for monitoring autophagy in the yeast Saccharomyces cerevisiae
    • Noda T, Matsuura A, Wada Y, Ohsumi Y (1995) Novel system for monitoring autophagy in the yeast Saccharomyces cerevisiae. Biochem. Biophys. Res. Commun. 210:126-132
    • (1995) Biochem Biophys Res Commun , vol.210 , pp. 126-132
    • Noda, T.1    Matsuura, A.2    Wada, Y.3    Ohsumi, Y.4
  • 35
    • 0032512636 scopus 로고    scopus 로고
    • TOR, a phosphatidylinositol kinase homologue, controls autophagy in yeast
    • Noda T, Ohsumi Y (1998) TOR, a phosphatidylinositol kinase homologue, controls autophagy in yeast. J Biol Chem. 273:3963-3966
    • (1998) J Biol Chem , vol.273 , pp. 3963-3966
    • Noda, T.1    Ohsumi, Y.2
  • 37
    • 0032403058 scopus 로고    scopus 로고
    • The TOR nutrient signalling pathway phosphorylates NPR1 and inhibits turnover of the tryptophan permease
    • Schmidt A, Beck T, Koller A, Kunz J, Hall MN (1998) The TOR nutrient signalling pathway phosphorylates NPR1 and inhibits turnover of the tryptophan permease. EMBO J. 17, 6924-6931
    • (1998) EMBO J , vol.17 , pp. 6924-6931
    • Schmidt, A.1    Beck, T.2    Koller, A.3    Kunz, J.4    Hall, M.N.5
  • 38
    • 0029913505 scopus 로고    scopus 로고
    • Cytoplasm-to-vacuole targeting and autophagy employ the same machinery to deliver proteins to the yeast vacuole
    • Scott SV, Hefner-Gravink A, Morano KA, Noda T, Ohsumi Y, Klionsky DJ (1996) Cytoplasm-to-vacuole targeting and autophagy employ the same machinery to deliver proteins to the yeast vacuole. Proc. Natl. Acad. Sci. U S A. 93:12304-12308
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 12304-12308
    • Scott, S.V.1    Hefner-Gravink, A.2    Morano, K.A.3    Noda, T.4    Ohsumi, Y.5    Klionsky, D.J.6
  • 40
    • 0026668042 scopus 로고
    • Autophagy in yeast demonstrated with proteinase-deficient mutants and conditions for its induction
    • Takeshige K, Baba, M, Tsuboi S, Noda T, Ohsumi Y (1992) Autophagy in yeast demonstrated with proteinase-deficient mutants and conditions for its induction. J. Cell Biol. 119:301-311
    • (1992) J Cell Biol , vol.119 , pp. 301-311
    • Takeshige, K.1    Baba, M.2    Tsuboi, S.3    Noda, T.4    Ohsumi, Y.5
  • 42
    • 0030707562 scopus 로고    scopus 로고
    • TOR signalling and control of cell growth
    • Thomas G, Hall MN (1997) TOR signalling and control of cell growth. Curr. Opi. in Cell Biol. 9, 782-787
    • (1997) Curr Opi in Cell Biol , vol.9 , pp. 782-787
    • Thomas, G.1    Hall, M.N.2
  • 44
    • 0027424777 scopus 로고
    • Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae
    • Tsukada M, Ohsumi Y (1993) Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae. FEBS Lett. 333:169-174
    • (1993) FEBS Lett , vol.333 , pp. 169-174
    • Tsukada, M.1    Ohsumi, Y.2
  • 45
    • 0034898851 scopus 로고    scopus 로고
    • Antagonistic controls of autophagy and glycogen accumulation by Snf1p, the yeast homolog of AMP-activated protein kinase, and the cyclin-dependent kinase Pho85p
    • Wang Z, Wilson WA, Fujino MA, Roach PJ (2001) Antagonistic controls of autophagy and glycogen accumulation by Snf1p, the yeast homolog of AMP-activated protein kinase, and the cyclin-dependent kinase Pho85p. Mol. Cell. Biol. 21:5742-5752
    • (2001) Mol Cell Biol , vol.21 , pp. 5742-5752
    • Wang, Z.1    Wilson, W.A.2    Fujino, M.A.3    Roach, P.J.4


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