Identification of active elementary flux modes in mitochondria using selectively permeabilized CHO cells

Metabolic Engineering

Volumn 32, Issue , 2015, Pages 95-105

  Nicolae, Averina ^a   Wahrheit, Judith ^a   Nonnenmacher, Yannic ^a,b   Weyler, Christian ^a   Heinzle, Elmar ^a  

^a SAARLAND UNIVERSITY   (Germany)

^b UNIVERSITY OF LUXEMBOURG   (Luxembourg)

Author keywords

CHO cells; Elementary mode analysis; Mammalian metabolism; Mitochondria; Permeabilized cells; Tricarboxylic acid cycle

Indexed keywords

AMINO ACIDS; BIOMOLECULES; CARBON DIOXIDE; CARBOXYLATION; CELLS; CYTOLOGY; MAMMALS; METABOLISM; METABOLITES; MITOCHONDRIA; PHYSIOLOGY;

CHINESE HAMSTER OVARY CELLS; CHO CELL; ELEMENTARY MODE ANALYSIS; ISOCITRATE DEHYDROGENASE; MITOCHONDRIAL METABOLISM; OXIDATIVE PHOSPHORYLATION; PERMEABILIZED CELLS; TRICARBOXYLIC ACID CYCLE;

SUBSTRATES;

2 OXOGLUTARIC ACID; ADENOSINE TRIPHOSPHATE; CITRIC ACID; GLUTAMINE; ISOCITRATE DEHYDROGENASE; MALATE DEHYDROGENASE; MALATE DEHYDROGENASE (DECARBOXYLATING); PYRUVATE CARBOXYLASE; PYRUVIC ACID; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; ADENOSINE DIPHOSPHATE; AMINO ACID; CARBON DIOXIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE; OXOGLUTARATE DEHYDROGENASE;

ALLOSTERISM; ANIMAL CELL; ARTICLE; CELL PERMEABILIZATION; CELL TRANSPORT; CHO CELL LINE; CITRIC ACID CYCLE; METABOLITE; MITOCHONDRIAL RESPIRATION; NONHUMAN; OXIDATIVE PHOSPHORYLATION; PRIORITY JOURNAL; RESPIRATORY CHAIN; STEADY STATE; ANIMAL; CRICETULUS; HAMSTER; METABOLISM; MITOCHONDRION;

ADENOSINE DIPHOSPHATE; AMINO ACIDS; ANIMALS; CARBON DIOXIDE; CHO CELLS; CITRATES; CITRIC ACID CYCLE; CRICETINAE; CRICETULUS; ISOCITRATE DEHYDROGENASE; KETOGLUTARATE DEHYDROGENASE COMPLEX; METABOLIC NETWORKS AND PATHWAYS; MITOCHONDRIA; NAD; OXIDATIVE PHOSPHORYLATION; PYRUVIC ACID;

EID: 84943524817     PISSN: 10967176     EISSN: 10967184     Source Type: Journal    
DOI: 10.1016/j.ymben.2015.09.014     Document Type: Article

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