-
1
-
-
0030914227
-
Metabolic engineering and human disease
-
Yarmush, M.L. & Berthiaume, F. Metabolic engineering and human disease. Nat. Biotechnol. 15, 525-528 (1997).
-
(1997)
Nat. Biotechnol.
, vol.15
, pp. 525-528
-
-
Yarmush, M.L.1
Berthiaume, F.2
-
2
-
-
0031004921
-
Metabolic fluxes in riboflavin-producing bacillus subtilis
-
Sauer, U. et al. Metabolic fluxes in riboflavin-producing Bacillus subtilis. Nat. Biotechnol. 15, 448-452 (1997).
-
(1997)
Nat. Biotechnol.
, vol.15
, pp. 448-452
-
-
Sauer, U.1
-
3
-
-
0030111235
-
Metabolism and evolution of haemophilus influenzae deduced from a whole-genome comparison with Escherichia coli
-
Tatusov, R.L. et al. Metabolism and evolution of Haemophilus influenzae deduced from a whole-genome comparison with Escherichia coli. Curr. Biol. 6, 279-291 (1996).
-
(1996)
Curr. Biol.
, vol.6
, pp. 279-291
-
-
Tatusov, R.L.1
-
4
-
-
0032491377
-
Predicting function: From genes to genomes and back
-
Bork, P. et al. Predicting function: from genes to genomes and back. J. Mol. Biol. 283, 707-725 (1998).
-
(1998)
J. Mol. Biol.
, vol.283
, pp. 707-725
-
-
Bork, P.1
-
5
-
-
0032516028
-
The underlying pathway structure of biochemical reaction networks
-
Schilling, C.H. & Palsson, B.O. The underlying pathway structure of biochemical reaction networks. Proc. Natl. Acad. Sci. USA 95, 4193-4198 (1998).
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 4193-4198
-
-
Schilling, C.H.1
Palsson, B.O.2
-
6
-
-
0030669030
-
Exploring the metabolic and genetic control of gene expression on a genomic scale
-
DeRisi, J.L., Iyer, V.R. & Brown, P.O. Exploring the metabolic and genetic control of gene expression on a genomic scale. Science 278, 680-686 (1997).
-
(1997)
Science
, vol.278
, pp. 680-686
-
-
DeRisi, J.L.1
Iyer, V.R.2
Brown, P.O.3
-
7
-
-
0032508046
-
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence
-
Cole, S.T. et al. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Nature 393, 537-544 (1998)
-
(1998)
Nature
, vol.393
, pp. 537-544
-
-
Cole, S.T.1
-
8
-
-
0033215210
-
Pathway alignment: Application to the comparative analysis of glycolytic enzymes
-
Dandekar, T., Schuster, S., Snel, B., Huynen, M. & Bork P. Pathway alignment: application to the comparative analysis of glycolytic enzymes, Biochem. J. 343, 115-124 (1999).
-
(1999)
Biochem. J.
, vol.343
, pp. 115-124
-
-
Dandekar, T.1
Schuster, S.2
Snel, B.3
Huynen, M.4
Bork, P.5
-
9
-
-
0022971582
-
MPS: An algorithm and data base for metabolic pathway synthesis
-
Seressiotis, A. & Bailey, J. E. MPS: an algorithm and data base for metabolic pathway synthesis. Biotechn. Lett. 8, 837-842 (1986).
-
(1986)
Biotechn. Lett.
, vol.8
, pp. 837-842
-
-
Seressiotis, A.1
Bailey, J.E.2
-
10
-
-
0025647585
-
Computer-aided synthesis of biochemical pathways
-
Mavrovouniotis, M.L., Stephanopoulos, G. & Stephanopoulos, G. Computer-aided synthesis of biochemical pathways. Biotechnol. Bioeng. 36, 1119-1132 (1990).
-
(1990)
Biotechnol. Bioeng.
, vol.36
, pp. 1119-1132
-
-
Mavrovouniotis, M.L.1
Stephanopoulos, G.2
Stephanopoulos, G.3
-
11
-
-
0343484086
-
-
(eds Schuster, S., Rigoulet, M., Ouhabi, R. & Mazat, J.-P.) Plenum, New York, NY;
-
Fell, D.A. in Modern trends in biothermokinetics (eds Schuster, S., Rigoulet, M., Ouhabi, R. & Mazat, J.-P.) 97-101 (Plenum, New York, NY; 1993).
-
(1993)
Modern Trends in Biothermokinetics
, pp. 97-101
-
-
Fell, D.A.1
-
12
-
-
0029014154
-
Two paradigms of metabolic engineering applied to amino acid biosynthesis
-
Simpson, T.W., Colon, G.E. & Stephanopoulos, G. Two paradigms of metabolic engineering applied to amino acid biosynthesis. Biochem. Soc. Trans. 23, 381-387 (1995).
-
(1995)
Biochem. Soc. Trans.
, vol.23
, pp. 381-387
-
-
Simpson, T.W.1
Colon, G.E.2
Stephanopoulos, G.3
-
13
-
-
0008338866
-
Complete set of steady states for the general stoichiometric dynamical system
-
Clarke, B.L. Complete set of steady states for the general stoichiometric dynamical system. J. Chem. Phys. 75, 4970-4979 (1981).
-
(1981)
J. Chem. Phys.
, vol.75
, pp. 4970-4979
-
-
Clarke, B.L.1
-
14
-
-
0023610603
-
On the analysis of substrate cycles in large metabolic systems
-
Leiser, J. & Blum, J.J. On the analysis of substrate cycles in large metabolic systems. Cell Biophys. 11, 123-138 (1987).
-
(1987)
Cell Biophys.
, vol.11
, pp. 123-138
-
-
Leiser, J.1
Blum, J.J.2
-
15
-
-
0000029295
-
On elementary flux modes in biochemical reaction systems at steady state
-
Schuster, S. & Hilgetag, C. On elementary flux modes in biochemical reaction systems at steady state. J. Biol. Syst. 2, 165-182 (1994).
-
(1994)
J. Biol. Syst.
, vol.2
, pp. 165-182
-
-
Schuster, S.1
Hilgetag, C.2
-
16
-
-
0000311393
-
-
(eds Cuthbertson, R., Holcombe, M. & Paton, R.) World Scientific, Singapore
-
Schuster, S., Hilgetag, C., Woods, J.H. & Fell, D.A. in Computation in cellular and molecular biological systems (eds Cuthbertson, R., Holcombe, M. & Paton, R.) 151-165 (World Scientific, Singapore, 1996).
-
(1996)
Computation in Cellular and Molecular Biological Systems
, pp. 151-165
-
-
Schuster, S.1
Hilgetag, C.2
Woods, J.H.3
Fell, D.A.4
-
17
-
-
0033080396
-
Detection of elementary flux modes in biochemical networks: A promising tool for pathway analysis and metabolic engineering
-
Schuster, S., Dandekar, T. & Fell, D. Detection of elementary flux modes in biochemical networks: a promising tool for pathway analysis and metabolic engineering. Trends Biotechnol. 17, 53-60 (1999).
-
(1999)
Trends Biotechnol.
, vol.17
, pp. 53-60
-
-
Schuster, S.1
Dandekar, T.2
Fell, D.3
-
18
-
-
0033136109
-
Metabolic pathway analysis: Basic concepts and scientific applications in the post-genomic era
-
Schilling, C.H., Schuster, S., Palsson, B.O. & Heinrich R. Metabolic pathway analysis: basic concepts and scientific applications in the post-genomic era. Biotechnol. Prog. 15, 296-303 (1999).
-
(1999)
Biotechnol. Prog.
, vol.15
, pp. 296-303
-
-
Schilling, C.H.1
Schuster, S.2
Palsson, B.O.3
Heinrich, R.4
-
19
-
-
0027537642
-
Refined algorithm and computer program for calculating all non-negative fluxes admissible in steady states of biochemical reaction systems with or without some flux rates fixed
-
Schuster, R. & Schuster, S. Refined algorithm and computer program for calculating all non-negative fluxes admissible in steady states of biochemical reaction systems with or without some flux rates fixed. Comp. Appl. Biosci. 9, 79-85 (1993).
-
(1993)
Comp. Appl. Biosci.
, vol.9
, pp. 79-85
-
-
Schuster, R.1
Schuster, S.2
-
20
-
-
0004155427
-
-
Freeman, New York, NY
-
Stryer, L. Biochemistry (Freeman, New York, NY; 1995).
-
(1995)
Biochemistry
-
-
Stryer, L.1
-
21
-
-
0020972416
-
Gluconeogenesis and related aspects of glycolysis
-
Hers, H.G. & Hue, L. Gluconeogenesis and related aspects of glycolysis. Annu. Rev. Biochem. 52, 617-653 (1983).
-
(1983)
Annu. Rev. Biochem.
, vol.52
, pp. 617-653
-
-
Hers, H.G.1
Hue, L.2
-
24
-
-
0028223931
-
Optimization of metabolism: The evolution of metabolic pathways toward simplicity through the game of the pentose phosphate cycle
-
Meléndez-Hevia, E., Waddell, T.G. & Montero, F. Optimization of metabolism: the evolution of metabolic pathways toward simplicity through the game of the pentose phosphate cycle. J. Theor. Biol. 166, 201-220 (1994).
-
(1994)
J. Theor. Biol.
, vol.166
, pp. 201-220
-
-
Meléndez-Hevia, E.1
Waddell, T.G.2
Montero, F.3
-
26
-
-
0030571222
-
Pathway analysis, engineering, and physiological considerations for redirecting central metabolism
-
Liao, J.C., Hou, S.-Y. & Chao, Y.-P. Pathway analysis, engineering, and physiological considerations for redirecting central metabolism. Biotechnol. Bioeng. 52, 129-140 (1996).
-
(1996)
Biotechnol. Bioeng.
, vol.52
, pp. 129-140
-
-
Liao, J.C.1
Hou, S.-Y.2
Chao, Y.-P.3
-
27
-
-
0031873963
-
New aspects of genes and enzymes for beta-lactam antibiotic biosynthesis
-
Martin, J.F. New aspects of genes and enzymes for beta-lactam antibiotic biosynthesis. Appl. Microbiol. Biotechnol. 50, 1-15 (1998).
-
(1998)
Appl. Microbiol. Biotechnol.
, vol.50
, pp. 1-15
-
-
Martin, J.F.1
-
28
-
-
0028867596
-
Biocatalytic syntheses of aromatics from D-glucose: Renewable microbial sources of aromatic compounds
-
Frost, J.W. & Draths, K.M. Biocatalytic syntheses of aromatics from D-glucose: renewable microbial sources of aromatic compounds. Annu. Rev. Microbiol. 49, 557-579 (1995).
-
(1995)
Annu. Rev. Microbiol.
, vol.49
, pp. 557-579
-
-
Frost, J.W.1
Draths, K.M.2
-
29
-
-
2642654227
-
MPW: The metabolic pathways database
-
Selkov, E. Jr., Grechkin, Y., Mikhailova, N. & Selkov, E. MPW: the metabolic pathways database. Nucleic Acids Res. 26, 43-45 (1998).
-
(1998)
Nucleic Acids Res.
, vol.26
, pp. 43-45
-
-
Selkov E., Jr.1
Grechkin, Y.2
Mikhailova, N.3
Selkov, E.4
-
30
-
-
0030878161
-
A robust view of biochemical pathways
-
Hartwell, L. A robust view of biochemical pathways. Nature 387, 855-857 (1997).
-
(1997)
Nature
, vol.387
, pp. 855-857
-
-
Hartwell, L.1
-
31
-
-
0002961439
-
-
(ed. Neidhardt, F.C.) ASM Press, Washington, DC
-
Cronan Jr., J.E. & LaPorte, D. in Escherichia coli and Salmonella. Cellular and molecular biology, Vol. 1 (ed. Neidhardt, F.C.) 206-215 (ASM Press, Washington, DC; 1996).
-
(1996)
Escherichia Coli and Salmonella. Cellular and Molecular Biology
, vol.1
, pp. 206-215
-
-
Cronan J.E., Jr.1
LaPorte, D.2
-
32
-
-
0030570128
-
Metabolic flux analysis of hybridoma cells in different culture media using mass balances
-
Bonarius, H.P.J. et al. Metabolic flux analysis of hybridoma cells in different culture media using mass balances. Biotechn. Bioeng. 50, 299-318 (1996).
-
(1996)
Biotechn. Bioeng.
, vol.50
, pp. 299-318
-
-
Bonarius, H.P.J.1
-
33
-
-
0031974007
-
Nonoxidative pentose phosphate pathways and their direct role in ribose synthesis in tumors: Is cancer a disease of cellular glucose metabolism?
-
Boros, L.G. et al. Nonoxidative pentose phosphate pathways and their direct role in ribose synthesis in tumors: is cancer a disease of cellular glucose metabolism? Med. Hypoth. 50, 55-59 (1998).
-
(1998)
Med. Hypoth.
, vol.50
, pp. 55-59
-
-
Boros, L.G.1
-
35
-
-
0031021873
-
Glycolysis in bloodstream form Trypanosoma brucei can be understood in terms of the kinetics of the glycolytic enzymes
-
Bakker, B.M., Michels, P.A.M., Opperdoes, F.R. & Westerhoff, H.V. Glycolysis in bloodstream form Trypanosoma brucei can be understood in terms of the kinetics of the glycolytic enzymes. J. Biol. Chem. 272, 3207-3215 (1997).
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 3207-3215
-
-
Bakker, B.M.1
Michels, P.A.M.2
Opperdoes, F.R.3
Westerhoff, H.V.4
-
36
-
-
0022423164
-
The aerobic/anaerobic transition of glucose metabolism in Trypanosoma brucei
-
Eisenthal, R. & Panes, A. The aerobic/anaerobic transition of glucose metabolism in Trypanosoma brucei. FEBS Lett. 181, 23-27 (1985).
-
(1985)
FEBS Lett.
, vol.181
, pp. 23-27
-
-
Eisenthal, R.1
Panes, A.2
-
37
-
-
84982039700
-
Oligomycin-sensitivity of hexose-sugar catabolism in the bloodstream form of Trypanosoma brucei brucei
-
Kiaira, J.K. & Njogu, M.R. Oligomycin-sensitivity of hexose-sugar catabolism in the bloodstream form of Trypanosoma brucei brucei Biotechnol. Appl. Biochem. 20, 347-356 (1994).
-
(1994)
Biotechnol. Appl. Biochem.
, vol.20
, pp. 347-356
-
-
Kiaira, J.K.1
Njogu, M.R.2
-
38
-
-
0027301842
-
A universal method for achieving increases in metabolite production
-
Kacser, H. & Acerenza, L. A universal method for achieving increases in metabolite production. Eur. J. Biochem. 216, 361-367 (1993).
-
(1993)
Eur. J. Biochem.
, vol.216
, pp. 361-367
-
-
Kacser, H.1
Acerenza, L.2
-
40
-
-
0030804853
-
Flux analysis of underdetermined metabolic networks: The quest for the missing constraints
-
Bonarius, H.P.J., Schmid, G. & Tramper, J. Flux analysis of underdetermined metabolic networks: the quest for the missing constraints. Trends Biotechn. 15, 308-314 (1997).
-
(1997)
Trends Biotechn.
, vol.15
, pp. 308-314
-
-
Bonarius, H.P.J.1
Schmid, G.2
Tramper, J.3
-
41
-
-
0030917475
-
Network organization of cell metabolism: Monosaccharide interconversion
-
Nuño, J.C., Sánchez-Valdenebro, I., Perez-Iratxeta, C., Meléndez-Hevia, E. & Montera, F. Network organization of cell metabolism: monosaccharide interconversion. Biochem. J. 324, 103-111 (1997).
-
(1997)
Biochem. J.
, vol.324
, pp. 103-111
-
-
Nuño, J.C.1
Sánchez-Valdenebro, I.2
Perez-Iratxeta, C.3
Meléndez-Hevia, E.4
Montera, F.5
-
42
-
-
0029076429
-
Natural selection of hemi- and heterozygotes for G6PD deficiency in Africa by resistance to severe malaria
-
Ruwende, C. et al. Natural selection of hemi- and heterozygotes for G6PD deficiency in Africa by resistance to severe malaria. Nature 376, 246-249 (1995)
-
(1995)
Nature
, vol.376
, pp. 246-249
-
-
Ruwende, C.1
-
43
-
-
0028834278
-
Targeted disruption of the housekeeping gene encoding glucose 6-phosphate dehydrogenase (G6PD): G6PD is dispensable for pentose synthesis but essential for defense against oxidative stress
-
Pandolfi, P.P. et al. Targeted disruption of the housekeeping gene encoding glucose 6-phosphate dehydrogenase (G6PD): G6PD is dispensable for pentose synthesis but essential for defense against oxidative stress. EMBO J. 14, 5209-5215 (1995).
-
(1995)
EMBO J.
, vol.14
, pp. 5209-5215
-
-
Pandolfi, P.P.1
-
44
-
-
0344052685
-
META-TOOL: For studying metabolic networks
-
Pfeiffer, T., Sánchez-Valdenebro, I., Nuño, J.C., Montero, F. & Schuster, S. META-TOOL: For studying metabolic networks, Bioinformatics 15 (1999) 251-257.
-
(1999)
Bioinformatics
, vol.15
, pp. 251-257
-
-
Pfeiffer, T.1
Sánchez-Valdenebro, I.2
Nuño, J.C.3
Montero, F.4
Schuster, S.5
|