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Volumn 48, Issue , 2015, Pages 147-164

The transcription factor nuclear factor interleukin 6 mediates pro- and anti-inflammatory responses during LPS-induced systemic inflammation in mice

Author keywords

Cytokines; Fever; Hypothalamic pituitary adrenal axis; Immune to brain signaling; Lipopolysaccharide; Neuroinflammation; Neutrophil granulocytes; NF IL6; Serotonin; Tryptophan metabolism

Indexed keywords

INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 10; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MESSENGER RNA; NUCLEAR FACTOR; PROSTAGLANDIN E SYNTHASE; CCAAT ENHANCER BINDING PROTEIN DELTA;

EID: 84942982598     PISSN: 08891591     EISSN: 10902139     Source Type: Journal    
DOI: 10.1016/j.bbi.2015.03.008     Document Type: Article
Times cited : (44)

References (118)
  • 1
    • 0842291550 scopus 로고    scopus 로고
    • Cell-specific pituitary gene expression profiles after treatment with leukemia inhibitory factor reveal novel modulators for proopiomelanocortin expression
    • Abbud, R.A., Kelleher, R., Melmed, S., 2004. Cell-specific pituitary gene expression profiles after treatment with leukemia inhibitory factor reveal novel modulators for proopiomelanocortin expression. Endocrinology 145, 867-880. http://dx.doi.org/10.1210/en.2003-0897.
    • (2004) Endocrinology , vol.145 , pp. 867-880
    • Abbud, R.A.1    Kelleher, R.2    Melmed, S.3
  • 2
    • 84908389493 scopus 로고    scopus 로고
    • Editorial: balancing tumor necrosis factor receptor I and tumor necrosis factor receptor II jointly for joint inflammation
    • Aggarwal, B.B., 2014. Editorial: balancing tumor necrosis factor receptor I and tumor necrosis factor receptor II jointly for joint inflammation. Arthritis Rheumatol. 66, 2657-2660. http://dx.doi.org/10.1002/art.38753.
    • (2014) Arthritis Rheumatol. , vol.66 , pp. 2657-2660
    • Aggarwal, B.B.1
  • 3
    • 0037394635 scopus 로고    scopus 로고
    • Overexpressed nuclear factor-kappaB can participate in endogenous C-reactive protein induction, and enhances the effects of C/EBPbeta and signal transducer and activator of transcription-3
    • Agrawal, A., Cha-Molstad, H., Samols, D., Kushner, I., 2003. Overexpressed nuclear factor-kappaB can participate in endogenous C-reactive protein induction, and enhances the effects of C/EBPbeta and signal transducer and activator of transcription-3. Immunology 108, 539-547.
    • (2003) Immunology , vol.108 , pp. 539-547
    • Agrawal, A.1    Cha-Molstad, H.2    Samols, D.3    Kushner, I.4
  • 4
    • 84899482930 scopus 로고    scopus 로고
    • Role of brain transmigrating neutrophils in depression-like behavior during systemic infection
    • Aguilar-Valles, A., Kim, J., Jung, S., Woodside, B., Luheshi, G.N., 2014. Role of brain transmigrating neutrophils in depression-like behavior during systemic infection. Mol. Psychiatry 19, 599-606. http://dx.doi.org/10.1038/mp.2013.137.
    • (2014) Mol. Psychiatry , vol.19 , pp. 599-606
    • Aguilar-Valles, A.1    Kim, J.2    Jung, S.3    Woodside, B.4    Luheshi, G.N.5
  • 6
    • 78149484622 scopus 로고    scopus 로고
    • In vivo deficiency of both C/EBPbeta and C/EBPepsilon results in highly defective myeloid differentiation and lack of cytokine response
    • Akagi, T., Thoennissen, N.H., George, A., Crooks, G., Song, J.H., Okamoto, R., Nowak, D., Gombart, A.F., Koeffler, H.P., 2010. In vivo deficiency of both C/EBPbeta and C/EBPepsilon results in highly defective myeloid differentiation and lack of cytokine response. PLoS One 5, e15419. http://dx.doi.org/10.1371/journal.pone.0015419.
    • (2010) PLoS One , vol.5
    • Akagi, T.1    Thoennissen, N.H.2    George, A.3    Crooks, G.4    Song, J.H.5    Okamoto, R.6    Nowak, D.7    Gombart, A.F.8    Koeffler, H.P.9
  • 7
    • 0026619974 scopus 로고
    • Regulation of expression of the interleukin 6 gene: structure and function of the transcription factor NF-IL6
    • Akira, S., Isshiki, H., Nakajima, T., Kinoshita, S., Nishio, Y., Natsuka, S., Kishimoto, T., 1992. Regulation of expression of the interleukin 6 gene: structure and function of the transcription factor NF-IL6. Ciba Found. Symp. 167, 47-62.
    • (1992) Ciba Found. Symp. , vol.167 , pp. 47-62
    • Akira, S.1    Isshiki, H.2    Nakajima, T.3    Kinoshita, S.4    Nishio, Y.5    Natsuka, S.6    Kishimoto, T.7
  • 9
    • 84883881295 scopus 로고    scopus 로고
    • Tryptophan: the key to boosting brain serotonin synthesis in depressive illness
    • Badawy, A.A., 2013. Tryptophan: the key to boosting brain serotonin synthesis in depressive illness. J. Psychopharmacol. 27, 878-893. http://dx.doi.org/10.1177/0269881113499209.
    • (2013) J. Psychopharmacol. , vol.27 , pp. 878-893
    • Badawy, A.A.1
  • 11
    • 0023870289 scopus 로고
    • The ACTH-immunoreactive system in the brain of the white-crowned sparrow, Zonotrichia leucophrys gambelii (Passeriformes, Emberizidae)
    • Blahser, S., 1988. The ACTH-immunoreactive system in the brain of the white-crowned sparrow, Zonotrichia leucophrys gambelii (Passeriformes, Emberizidae). Histochemistry 88, 309-312.
    • (1988) Histochemistry , vol.88 , pp. 309-312
    • Blahser, S.1
  • 12
    • 84883885115 scopus 로고    scopus 로고
    • Serotonin and beyond: therapeutics for major depression
    • Blier, P., El Mansari, M., 2013. Serotonin and beyond: therapeutics for major depression. Philos. Trans. R. Soc. Lond. B Biol. Sci. 368, 20120536. http://dx.doi.org/10.1098/rstb.2012.0536.
    • (2013) Philos. Trans. R. Soc. Lond. B Biol. Sci. , vol.368 , pp. 20120536
    • Blier, P.1    El Mansari, M.2
  • 13
    • 79953662385 scopus 로고    scopus 로고
    • Immune system to brain signaling: neuropsychopharmacological implications
    • Capuron, L., Miller, A.H., 2011. Immune system to brain signaling: neuropsychopharmacological implications. Pharmacol. Ther. 130, 226-238. http://dx.doi.org/10.1016/j.pharmthera.2011.01.014.
    • (2011) Pharmacol. Ther. , vol.130 , pp. 226-238
    • Capuron, L.1    Miller, A.H.2
  • 15
    • 0033836856 scopus 로고    scopus 로고
    • Circulating interleukin-6 mediates the febrile response to localised inflammation in rats
    • Cartmell, T., Poole, S., Turnbull, A.V., Rothwell, N.J., Luheshi, G.N., 2000. Circulating interleukin-6 mediates the febrile response to localised inflammation in rats. J. Physiol. 526 (Pt. 3), 653-661.
    • (2000) J. Physiol , vol.526 , pp. 653-661
    • Cartmell, T.1    Poole, S.2    Turnbull, A.V.3    Rothwell, N.J.4    Luheshi, G.N.5
  • 16
    • 84862918916 scopus 로고    scopus 로고
    • Advances in tryptophan hydroxylase-2 gene expression regulation: new insights into serotonin-stress interaction and clinical implications
    • Chen, G.L., Miller, G.M., 2012. Advances in tryptophan hydroxylase-2 gene expression regulation: new insights into serotonin-stress interaction and clinical implications. Am. J. Med. Genet. B Neuropsychiatr. Genet. 159B, 152-171. http://dx.doi.org/10.1002/ajmg.b.32023.
    • (2012) Am. J. Med. Genet. B Neuropsychiatr. Genet. , vol.159B , pp. 152-171
    • Chen, G.L.1    Miller, G.M.2
  • 17
    • 34848920411 scopus 로고    scopus 로고
    • Endothelial-specific knockdown of interleukin-1 (IL-1) type 1 receptor differentially alters CNS responses to IL-1 depending on its route of administration
    • Ching, S., Zhang, H., Belevych, N., He, L., Lai, W., Pu, X.A., Jaeger, L.B., Chen, Q., Quan, N., 2007. Endothelial-specific knockdown of interleukin-1 (IL-1) type 1 receptor differentially alters CNS responses to IL-1 depending on its route of administration. J. Neurosci. 27, 10476-10486. http://dx.doi.org/10.1523/JNEUROSCI.3357-07.2007.
    • (2007) J. Neurosci. , vol.27 , pp. 10476-10486
    • Ching, S.1    Zhang, H.2    Belevych, N.3    He, L.4    Lai, W.5    Pu, X.A.6    Jaeger, L.B.7    Chen, Q.8    Quan, N.9
  • 19
    • 60849135712 scopus 로고    scopus 로고
    • Cerebral microglia recruit monocytes into the brain in response to tumor necrosis factoralpha signaling during peripheral organ inflammation
    • D'Mello, C., Le, T., Swain, M.G., 2009. Cerebral microglia recruit monocytes into the brain in response to tumor necrosis factoralpha signaling during peripheral organ inflammation. J. Neurosci. 29, 2089-2102. http://dx.doi.org/10.1523/JNEUROSCI.3567-08.2009.
    • (2009) J. Neurosci. , vol.29 , pp. 2089-2102
    • D'Mello, C.1    Le, T.2    Swain, M.G.3
  • 20
    • 84878158252 scopus 로고    scopus 로고
    • The putative JAKSTAT inhibitor AG490 exacerbates LPS-fever, reduces sickness behavior, and alters the expression of pro- and anti-inflammatory genes in the rat brain
    • Damm, J., Harden, L.M., Gerstberger, R., Roth, J., Rummel, C., 2013. The putative JAKSTAT inhibitor AG490 exacerbates LPS-fever, reduces sickness behavior, and alters the expression of pro- and anti-inflammatory genes in the rat brain. Neuropharmacology 71, 98-111. http://dx.doi.org/10.1016/j.neuropharm.2013.03.014.
    • (2013) Neuropharmacology , vol.71 , pp. 98-111
    • Damm, J.1    Harden, L.M.2    Gerstberger, R.3    Roth, J.4    Rummel, C.5
  • 21
    • 78650636800 scopus 로고    scopus 로고
    • Spatiotemporal nuclear factor interleukin-6 expression in the rat brain during lipopolysaccharide-induced fever is linked to sustained hypothalamic inflammatory target gene induction
    • Damm, J., Luheshi, G.N., Gerstberger, R., Roth, J., Rummel, C., 2011. Spatiotemporal nuclear factor interleukin-6 expression in the rat brain during lipopolysaccharide-induced fever is linked to sustained hypothalamic inflammatory target gene induction. J. Comp. Neurol. 519, 480-505. http://dx.doi.org/10.1002/cne.22529.
    • (2011) J. Comp. Neurol. , vol.519 , pp. 480-505
    • Damm, J.1    Luheshi, G.N.2    Gerstberger, R.3    Roth, J.4    Rummel, C.5
  • 22
    • 84855557761 scopus 로고    scopus 로고
    • Fever, sickness behavior, and expression of inflammatory genes in the hypothalamus after systemic and localized subcutaneous stimulation of rats with the Toll-like receptor 7 agonist imiquimod
    • Damm, J., Wiegand, F., Harden, L.M., Gerstberger, R., Rummel, C., Roth, J., 2012. Fever, sickness behavior, and expression of inflammatory genes in the hypothalamus after systemic and localized subcutaneous stimulation of rats with the Toll-like receptor 7 agonist imiquimod. Neuroscience 201, 166-183. http://dx.doi.org/10.1016/j.neuroscience.2011.11.013.
    • (2012) Neuroscience , vol.201 , pp. 166-183
    • Damm, J.1    Wiegand, F.2    Harden, L.M.3    Gerstberger, R.4    Rummel, C.5    Roth, J.6
  • 23
    • 84919333843 scopus 로고    scopus 로고
    • Intraperitoneal and subcutaneous injections of the TLR9 agonist ODN 1668 in rats: brain inflammatory responses are related to peripheral IL-6 rather than interferons
    • Damm, J., Wiegand, F., Harden, L.M., Wenisch, S., Gerstberger, R., Rummel, C., Roth, J., 2014. Intraperitoneal and subcutaneous injections of the TLR9 agonist ODN 1668 in rats: brain inflammatory responses are related to peripheral IL-6 rather than interferons. J. Neuroimmunol. 277, 105-117. http://dx.doi.org/10.1016/j.jneuroim.2014.10.007.
    • (2014) J. Neuroimmunol. , vol.277 , pp. 105-117
    • Damm, J.1    Wiegand, F.2    Harden, L.M.3    Wenisch, S.4    Gerstberger, R.5    Rummel, C.6    Roth, J.7
  • 24
    • 37249094173 scopus 로고    scopus 로고
    • From inflammation to sickness and depression: when the immune system subjugates the brain
    • Dantzer, R., O'Connor, J.C., Freund, G.G., Johnson, R.W., Kelley, K.W., 2008. From inflammation to sickness and depression: when the immune system subjugates the brain. Nat. Rev. Neurosci. 9, 46-56. http://dx.doi.org/10.1038/nrn2297.
    • (2008) Nat. Rev. Neurosci. , vol.9 , pp. 46-56
    • Dantzer, R.1    O'Connor, J.C.2    Freund, G.G.3    Johnson, R.W.4    Kelley, K.W.5
  • 25
    • 84925702647 scopus 로고    scopus 로고
    • Is there a role for glutamate-mediated excitotoxicity in inflammation-induced depression?
    • Dantzer, R., Walker, A.K., 2014. Is there a role for glutamate-mediated excitotoxicity in inflammation-induced depression? J. Neural Transm. http://dx.doi.org/10.1007/s00702-014-1187-1.
    • (2014) J. Neural Transm
    • Dantzer, R.1    Walker, A.K.2
  • 26
    • 0034904975 scopus 로고    scopus 로고
    • Expression and function of CCAAT/enhancer binding proteinbeta (C/EBPbeta) LAP and LIP isoforms in mouse mammary gland, tumors and cultured mammary epithelial cells
    • Dearth, L.R., Hutt, J., Sattler, A., Gigliotti, A., DeWille, J., 2001. Expression and function of CCAAT/enhancer binding proteinbeta (C/EBPbeta) LAP and LIP isoforms in mouse mammary gland, tumors and cultured mammary epithelial cells. J. Cell. Biochem. 82, 357-370.
    • (2001) J. Cell. Biochem. , vol.82 , pp. 357-370
    • Dearth, L.R.1    Hutt, J.2    Sattler, A.3    Gigliotti, A.4    DeWille, J.5
  • 27
    • 77954537848 scopus 로고    scopus 로고
    • Coordinated up-regulation of cyclooxygenase-2 and microsomal prostaglandin E synthase 1 transcription by nuclear factor kappa B and early growth response-1 in macrophages
    • Diaz-Munoz, M.D., Osma-Garcia, I.C., Cacheiro-Llaguno, C., Fresno, M., Iniguez, M.A., 2010. Coordinated up-regulation of cyclooxygenase-2 and microsomal prostaglandin E synthase 1 transcription by nuclear factor kappa B and early growth response-1 in macrophages. Cell. Signal. 22, 1427-1436. http://dx.doi.org/10.1016/j.cellsig.2010.05.011.
    • (2010) Cell. Signal. , vol.22 , pp. 1427-1436
    • Diaz-Munoz, M.D.1    Osma-Garcia, I.C.2    Cacheiro-Llaguno, C.3    Fresno, M.4    Iniguez, M.A.5
  • 28
    • 0021780387 scopus 로고
    • The heterogeneity of mononuclear phagocytes in lymphoid organs: distinct macrophage subpopulations in rat recognized by monoclonal antibodies ED1, ED2 and ED3
    • Dijkstra, C.D., Dopp, E.A., Joling, P., Kraal, G., 1985. The heterogeneity of mononuclear phagocytes in lymphoid organs: distinct macrophage subpopulations in rat recognized by monoclonal antibodies ED1, ED2 and ED3. Adv. Exp. Med. Biol. 186, 409-419.
    • (1985) Adv. Exp. Med. Biol. , vol.186 , pp. 409-419
    • Dijkstra, C.D.1    Dopp, E.A.2    Joling, P.3    Kraal, G.4
  • 30
    • 0033563095 scopus 로고    scopus 로고
    • Central role of transcription factor NF-IL6 for cytokine and iron-mediated regulation of murine inducible nitric oxide synthase expression
    • Dlaska, M., Weiss, G., 1999. Central role of transcription factor NF-IL6 for cytokine and iron-mediated regulation of murine inducible nitric oxide synthase expression. J. Immunol. 162, 6171-6177.
    • (1999) J. Immunol. , vol.162 , pp. 6171-6177
    • Dlaska, M.1    Weiss, G.2
  • 31
    • 33845948245 scopus 로고    scopus 로고
    • Upregulation of CCAAT/enhancer binding protein beta in activated astrocytes and microglia
    • Ejarque-Ortiz, A., Medina, M.G., Tusell, J.M., Perez-Gonzalez, A.P., Serratosa, J., Saura, J., 2007. Upregulation of CCAAT/enhancer binding protein beta in activated astrocytes and microglia. Glia 55, 178-188. http://dx.doi.org/10.1002/glia.20446.
    • (2007) Glia , vol.55 , pp. 178-188
    • Ejarque-Ortiz, A.1    Medina, M.G.2    Tusell, J.M.3    Perez-Gonzalez, A.P.4    Serratosa, J.5    Saura, J.6
  • 32
    • 0037152234 scopus 로고    scopus 로고
    • Induction of microsomal prostaglandin E synthase in the rat brain endothelium and parenchyma in adjuvant-induced arthritis
    • Engblom, D., Ek, M., Andersson, I.M., Saha, S., Dahlstrom, M., Jakobsson, P.J., Ericsson-Dahlstrand, A., Blomqvist, A., 2002. Induction of microsomal prostaglandin E synthase in the rat brain endothelium and parenchyma in adjuvant-induced arthritis. J. Comp. Neurol. 452, 205-214. http://dx.doi.org/10.1002/cne.10380.
    • (2002) J. Comp. Neurol. , vol.452 , pp. 205-214
    • Engblom, D.1    Ek, M.2    Andersson, I.M.3    Saha, S.4    Dahlstrom, M.5    Jakobsson, P.J.6    Ericsson-Dahlstrand, A.7    Blomqvist, A.8
  • 33
    • 84911893311 scopus 로고    scopus 로고
    • Immune-induced fever is mediated by IL-6 receptors on brain endothelial cells coupled to STAT3-dependent induction of brain endothelial prostaglandin synthesis
    • Eskilsson, A., Mirrasekhian, E., Dufour, S., Schwaninger, M., Engblom, D., Blomqvist, A., 2014. Immune-induced fever is mediated by IL-6 receptors on brain endothelial cells coupled to STAT3-dependent induction of brain endothelial prostaglandin synthesis. J. Neurosci. 34, 15957-15961. http://dx.doi.org/10.1523/JNEUROSCI.3520-14.2014.
    • (2014) J. Neurosci. , vol.34 , pp. 15957-15961
    • Eskilsson, A.1    Mirrasekhian, E.2    Dufour, S.3    Schwaninger, M.4    Engblom, D.5    Blomqvist, A.6
  • 34
    • 67349083526 scopus 로고    scopus 로고
    • MiR-155 gene: a typical multifunctional microRNA
    • Faraoni, I., Antonetti, F.R., Cardone, J., Bonmassar, E., 2009. MiR-155 gene: a typical multifunctional microRNA. Biochim. Biophys. Acta 1792, 497-505. http://dx.doi.org/10.1016/j.bbadis.2009.02.013.
    • (2009) Biochim. Biophys. Acta , vol.1792 , pp. 497-505
    • Faraoni, I.1    Antonetti, F.R.2    Cardone, J.3    Bonmassar, E.4
  • 35
    • 84888148371 scopus 로고    scopus 로고
    • Activation of the inflammatory transcription factor nuclear factor interleukin-6 during inflammatory and psychological stress in the brain
    • Fuchs, F., Damm, J., Gerstberger, R., Roth, J., Rummel, C., 2013. Activation of the inflammatory transcription factor nuclear factor interleukin-6 during inflammatory and psychological stress in the brain. J. Neuroinflammation 10, 140. http://dx.doi.org/10.1186/1742-2094-10-140.
    • (2013) J. Neuroinflammation , vol.10 , pp. 140
    • Fuchs, F.1    Damm, J.2    Gerstberger, R.3    Roth, J.4    Rummel, C.5
  • 36
    • 0037025051 scopus 로고    scopus 로고
    • Spatiotemporal analysis of signal transducer and activator of transcription 3 activation in rat brain astrocytes and pituitary following peripheral immune challenge
    • Gautron, L., Lafon, P., Chaigniau, M., Tramu, G., Laye, S., 2002. Spatiotemporal analysis of signal transducer and activator of transcription 3 activation in rat brain astrocytes and pituitary following peripheral immune challenge. Neuroscience 112, 717-729.
    • (2002) Neuroscience , vol.112 , pp. 717-729
    • Gautron, L.1    Lafon, P.2    Chaigniau, M.3    Tramu, G.4    Laye, S.5
  • 37
    • 0024520462 scopus 로고
    • Identity of ED2-positive perivascular cells in rat brain
    • Graeber, M.B., Streit, W.J., Kreutzberg, G.W., 1989. Identity of ED2-positive perivascular cells in rat brain. J. Neurosci. Res. 22, 103-106. http://dx.doi.org/10.1002/jnr.490220114.
    • (1989) J. Neurosci. Res. , vol.22 , pp. 103-106
    • Graeber, M.B.1    Streit, W.J.2    Kreutzberg, G.W.3
  • 38
    • 0141818113 scopus 로고    scopus 로고
    • A critical role for C/EBPbeta binding to the AABS promoter response element in the human iNOS gene
    • Guo, Z., Shao, L., Feng, X., Reid, K., Marderstein, E., Nakao, A., Geller, D.A., 2003. A critical role for C/EBPbeta binding to the AABS promoter response element in the human iNOS gene. FASEB J. 17, 1718-1720. http://dx.doi.org/10.1096/fj.02-1172fje.
    • (2003) FASEB J. , vol.17 , pp. 1718-1720
    • Guo, Z.1    Shao, L.2    Feng, X.3    Reid, K.4    Marderstein, E.5    Nakao, A.6    Geller, D.A.7
  • 39
    • 0036889766 scopus 로고    scopus 로고
    • Cytokines and neuro-immuneendocrine interactions: a role for the hypothalamic-pituitary-adrenal revolving axis
    • Haddad, J.J., Saade, N.E., Safieh-Garabedian, B., 2002. Cytokines and neuro-immuneendocrine interactions: a role for the hypothalamic-pituitary-adrenal revolving axis. J. Neuroimmunol. 133, 1-19.
    • (2002) J. Neuroimmunol. , vol.133 , pp. 1-19
    • Haddad, J.J.1    Saade, N.E.2    Safieh-Garabedian, B.3
  • 40
    • 44649199238 scopus 로고    scopus 로고
    • Loss of c/EBP-beta activity promotes the adaptive to apoptotic switch in hypoxic cortical neurons
    • Halterman, M.W., De Jesus, C., Rempe, D.A., Schor, N.F., Federoff, H.J., 2008. Loss of c/EBP-beta activity promotes the adaptive to apoptotic switch in hypoxic cortical neurons. Mol. Cell. Neurosci. 38, 125-137. http://dx.doi.org/10.1016/j.mcn.2008.01.014.
    • (2008) Mol. Cell. Neurosci. , vol.38 , pp. 125-137
    • Halterman, M.W.1    De Jesus, C.2    Rempe, D.A.3    Schor, N.F.4    Federoff, H.J.5
  • 41
    • 79954510531 scopus 로고    scopus 로고
    • Temporal phasing of locomotor activity, heart rate rhythmicity, and core body temperature is disrupted in VIP receptor 2-deficient mice
    • Hannibal, J., Hsiung, H.M., Fahrenkrug, J., 2011. Temporal phasing of locomotor activity, heart rate rhythmicity, and core body temperature is disrupted in VIP receptor 2-deficient mice. Am. J. Physiol. Regul. Integr. Comp. Physiol. 300, R519-530. http://dx.doi.org/10.1152/ajpregu.00599.2010.
    • (2011) Am. J. Physiol. Regul. Integr. Comp. Physiol. , vol.300 , pp. R519-R530
    • Hannibal, J.1    Hsiung, H.M.2    Fahrenkrug, J.3
  • 42
    • 84904596490 scopus 로고    scopus 로고
    • Critical role for peripherally-derived interleukin-10 in mediating the thermoregulatory manifestations of fever and hypothermia in severe forms of lipopolysaccharide-induced inflammation
    • Harden, L.M., Rummel, C., Laburn, H.P., Damm, J., Wiegand, F., Poole, S., Gerstberger, R., Roth, J., 2014. Critical role for peripherally-derived interleukin-10 in mediating the thermoregulatory manifestations of fever and hypothermia in severe forms of lipopolysaccharide-induced inflammation. Pflugers Arch. 466, 1451-1466. http://dx.doi.org/10.1007/s00424-013-1371-4.
    • (2014) Pflugers Arch. , vol.466 , pp. 1451-1466
    • Harden, L.M.1    Rummel, C.2    Laburn, H.P.3    Damm, J.4    Wiegand, F.5    Poole, S.6    Gerstberger, R.7    Roth, J.8
  • 43
    • 0036081846 scopus 로고    scopus 로고
    • Selected contribution: role of IL-6 in LPS-induced nuclear STAT3 translocation in sensory circumventricular organs during fever in rats
    • Harre, E.M., Roth, J., Pehl, U., Kueth, M., Gerstberger, R., Hubschle, T., 2002. Selected contribution: role of IL-6 in LPS-induced nuclear STAT3 translocation in sensory circumventricular organs during fever in rats. J. Appl. Physiol. 92, 2657-2666. http://dx.doi.org/10.1152/japplphysiol.00822.2001.
    • (2002) J. Appl. Physiol. , vol.92 , pp. 2657-2666
    • Harre, E.M.1    Roth, J.2    Pehl, U.3    Kueth, M.4    Gerstberger, R.5    Hubschle, T.6
  • 45
    • 84900509461 scopus 로고    scopus 로고
    • Serotonin transporter polymorphisms (5-HTTLPR) in emotion processing implications from current neurobiology
    • Jonassen, R., Landro, N.I., 2014. Serotonin transporter polymorphisms (5-HTTLPR) in emotion processing implications from current neurobiology. Prog. Neurobiol. http://dx.doi.org/10.1016/j.pneurobio.2014.02.003.
    • (2014) Prog. Neurobiol
    • Jonassen, R.1    Landro, N.I.2
  • 46
    • 3543077645 scopus 로고    scopus 로고
    • Distribution of vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide receptors (VPAC1, VPAC2, and PAC1 receptor) in the rat brain
    • Joo, K.M., Chung, Y.H., Kim, M.K., Nam, R.H., Lee, B.L., Lee, K.H., Cha, C.I., 2004. Distribution of vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide receptors (VPAC1, VPAC2, and PAC1 receptor) in the rat brain. J. Comp. Neurol. 476, 388-413. http://dx.doi.org/10.1002/cne.20231.
    • (2004) J. Comp. Neurol. , vol.476 , pp. 388-413
    • Joo, K.M.1    Chung, Y.H.2    Kim, M.K.3    Nam, R.H.4    Lee, B.L.5    Lee, K.H.6    Cha, C.I.7
  • 47
    • 33748089027 scopus 로고    scopus 로고
    • Decreased brain damage and curtailed inflammation in transcription factor CCAAT/enhancer binding protein beta knockout mice following transient focal cerebral ischemia
    • Kapadia, R., Tureyen, K., Bowen, K.K., Kalluri, H., Johnson, P.F., Vemuganti, R., 2006. Decreased brain damage and curtailed inflammation in transcription factor CCAAT/enhancer binding protein beta knockout mice following transient focal cerebral ischemia. J. Neurochem. 98, 1718-1731. http://dx.doi.org/10.1111/j.1471-4159.2006.04056.x.
    • (2006) J. Neurochem. , vol.98 , pp. 1718-1731
    • Kapadia, R.1    Tureyen, K.2    Bowen, K.K.3    Kalluri, H.4    Johnson, P.F.5    Vemuganti, R.6
  • 48
    • 84864772397 scopus 로고    scopus 로고
    • Brain indoleamine 2,3-dioxygenase contributes to the comorbidity of pain and depression
    • Kim, H., Chen, L., Lim, G., Sung, B., Wang, S., McCabe, M.F., Rusanescu, G., Yang, L., Tian, Y., Mao, J., 2012. Brain indoleamine 2,3-dioxygenase contributes to the comorbidity of pain and depression. J. Clin. Invest. 122, 2940-2954. http://dx.doi.org/10.1172/JCI61884.
    • (2012) J. Clin. Invest. , vol.122 , pp. 2940-2954
    • Kim, H.1    Chen, L.2    Lim, G.3    Sung, B.4    Wang, S.5    McCabe, M.F.6    Rusanescu, G.7    Yang, L.8    Tian, Y.9    Mao, J.10
  • 49
    • 1642544092 scopus 로고    scopus 로고
    • Gender-dependent alterations in corticosteroid receptor status and spatial performance following 21 days of restraint stress
    • Kitraki, E., Kremmyda, O., Youlatos, D., Alexis, M.N., Kittas, C., 2004. Gender-dependent alterations in corticosteroid receptor status and spatial performance following 21 days of restraint stress. Neuroscience 125, 47-55. http://dx.doi.org/10.1016/j.neuroscience.2003.12.024.
    • (2004) Neuroscience , vol.125 , pp. 47-55
    • Kitraki, E.1    Kremmyda, O.2    Youlatos, D.3    Alexis, M.N.4    Kittas, C.5
  • 50
    • 0028950377 scopus 로고
    • Systemic but not central administration of tumor necrosis factor-alpha attenuates LPS-induced fever in rats
    • Klir, J.J., McClellan, J.L., Kozak, W., Szelenyi, Z., Wong, G.H., Kluger, M.J., 1995. Systemic but not central administration of tumor necrosis factor-alpha attenuates LPS-induced fever in rats. Am. J. Physiol. 268, R480-486.
    • (1995) Am. J. Physiol. , vol.268 , pp. R480-R486
    • Klir, J.J.1    McClellan, J.L.2    Kozak, W.3    Szelenyi, Z.4    Wong, G.H.5    Kluger, M.J.6
  • 51
    • 84891825307 scopus 로고    scopus 로고
    • Leptin is involved in age-dependent changes in response to systemic inflammation in the rat
    • Koenig, S., Luheshi, G.N., Wenz, T., Gerstberger, R., Roth, J., Rummel, C., 2014. Leptin is involved in age-dependent changes in response to systemic inflammation in the rat. Brain Behav. Immun. 36, 128-138. http://dx.doi.org/10.1016/j.bbi.2013.10.019.
    • (2014) Brain Behav. Immun. , vol.36 , pp. 128-138
    • Koenig, S.1    Luheshi, G.N.2    Wenz, T.3    Gerstberger, R.4    Roth, J.5    Rummel, C.6
  • 52
    • 0029127943 scopus 로고
    • TNF soluble receptor and antiserum against TNF enhance lipopolysaccharide fever in mice
    • Kozak, W., Conn, C.A., Klir, J.J., Wong, G.H., Kluger, M.J., 1995. TNF soluble receptor and antiserum against TNF enhance lipopolysaccharide fever in mice. Am. J. Physiol. 269, R23-29.
    • (1995) Am. J. Physiol. , vol.269 , pp. R23-R29
    • Kozak, W.1    Conn, C.A.2    Klir, J.J.3    Wong, G.H.4    Kluger, M.J.5
  • 53
    • 0038826627 scopus 로고    scopus 로고
    • Genetic Models in Applied Physiology. Differential role of nitric oxide synthase isoforms in fever of different etiologies: studies using Nos gene-deficient mice
    • Kozak A (2003)
    • Kozak, W., Kozak, A., 2003. Kozak A (2003), Genetic Models in Applied Physiology. Differential role of nitric oxide synthase isoforms in fever of different etiologies: studies using Nos gene-deficient mice. J. Appl. Physiol. 94, 2534-2544. http://dx.doi.org/10.1152/japplphysiol.01042.2002.
    • (2003) J. Appl. Physiol. , vol.94 , pp. 2534-2544
    • Kozak, W.1    Kozak, A.2
  • 54
    • 33646487906 scopus 로고    scopus 로고
    • Pyrogenicity of CpG-DNA in mice: role of interleukin-6, cyclooxygenases, and nuclear factor-kappaB
    • Kozak, W., Wrotek, S., Kozak, A., 2006. Pyrogenicity of CpG-DNA in mice: role of interleukin-6, cyclooxygenases, and nuclear factor-kappaB. Am. J. Physiol. Regul. Integr. Comp. Physiol. 290, R871-880. http://dx.doi.org/10.1152/ajpregu.00408.2005.
    • (2006) Am. J. Physiol. Regul. Integr. Comp. Physiol. , vol.290 , pp. R871-R880
    • Kozak, W.1    Wrotek, S.2    Kozak, A.3
  • 55
    • 0033038790 scopus 로고    scopus 로고
    • Effects of systemic immunogenic insults and circulating proinflammatory cytokines on the transcription of the inhibitory factor kappaB alpha within specific cellular populations of the rat brain
    • Laflamme, N., Rivest, S., 1999. Effects of systemic immunogenic insults and circulating proinflammatory cytokines on the transcription of the inhibitory factor kappaB alpha within specific cellular populations of the rat brain. J. Neurochem. 73, 309-321.
    • (1999) J. Neurochem. , vol.73 , pp. 309-321
    • Laflamme, N.1    Rivest, S.2
  • 56
    • 34548317001 scopus 로고    scopus 로고
    • EP3 prostaglandin receptors in the median preoptic nucleus are critical for fever responses
    • Lazarus, M., Yoshida, K., Coppari, R., Bass, C.E., Mochizuki, T., Lowell, B.B., Saper, C.B., 2007. EP3 prostaglandin receptors in the median preoptic nucleus are critical for fever responses. Nat. Neurosci. 10, 1131-1133. http://dx.doi.org/10.1038/nn1949.
    • (2007) Nat. Neurosci. , vol.10 , pp. 1131-1133
    • Lazarus, M.1    Yoshida, K.2    Coppari, R.3    Bass, C.E.4    Mochizuki, T.5    Lowell, B.B.6    Saper, C.B.7
  • 57
    • 0033735522 scopus 로고    scopus 로고
    • Selective involvement of interleukin-6 in the transcriptional activation of the suppressor of cytokine signaling-3 in the brain during systemic immune challenges
    • Lebel, E., Vallieres, L., Rivest, S., 2000. Selective involvement of interleukin-6 in the transcriptional activation of the suppressor of cytokine signaling-3 in the brain during systemic immune challenges. Endocrinology 141, 3749-3763. http://dx.doi.org/10.1210/endo.141.10.7695.
    • (2000) Endocrinology , vol.141 , pp. 3749-3763
    • Lebel, E.1    Vallieres, L.2    Rivest, S.3
  • 59
    • 31844432926 scopus 로고    scopus 로고
    • The HPA and immune axes in stress: the involvement of the serotonergic system
    • Leonard, B.E., 2005. The HPA and immune axes in stress: the involvement of the serotonergic system. Eur. Psychiatry 20 (Suppl. 3), S302-306.
    • (2005) Eur. Psychiatry , vol.20 , pp. S302-S306
    • Leonard, B.E.1
  • 60
    • 80054918892 scopus 로고    scopus 로고
    • TNFalpha-induced up-regulation of miR-155 inhibits adipogenesis by down-regulating early adipogenic transcription factors
    • Liu, S., Yang, Y., Wu, J., 2011. TNFalpha-induced up-regulation of miR-155 inhibits adipogenesis by down-regulating early adipogenic transcription factors. Biochem. Biophys. Res. Commun. 414, 618-624. http://dx.doi.org/10.1016/j.bbrc.2011.09.131.
    • (2011) Biochem. Biophys. Res. Commun. , vol.414 , pp. 618-624
    • Liu, S.1    Yang, Y.2    Wu, J.3
  • 61
    • 0037769043 scopus 로고    scopus 로고
    • Functional cooperation of simian virus 40 promoter factor 1 and CCAAT/enhancer-binding protein beta and delta in lipopolysaccharide-induced gene activation of IL-10 in mouse macrophages
    • Liu, Y.W., Tseng, H.P., Chen, L.C., Chen, B.K., Chang, W.C., 2003. Functional cooperation of simian virus 40 promoter factor 1 and CCAAT/enhancer-binding protein beta and delta in lipopolysaccharide-induced gene activation of IL-10 in mouse macrophages. J. Immunol. 171, 821-828.
    • (2003) J. Immunol. , vol.171 , pp. 821-828
    • Liu, Y.W.1    Tseng, H.P.2    Chen, L.C.3    Chen, B.K.4    Chang, W.C.5
  • 62
    • 33845919736 scopus 로고    scopus 로고
    • Baseline and stress-induced plasma corticosterone concentrations of mice selectively bred for high voluntary wheel running
    • Malisch, J.L., Saltzman, W., Gomes, F.R., Rezende, E.L., Jeske, D.R., Garland Jr., T., 2007. Baseline and stress-induced plasma corticosterone concentrations of mice selectively bred for high voluntary wheel running. Physiol. Biochem. Zool. 80, 146-156. http://dx.doi.org/10.1086/508828.
    • (2007) Physiol. Biochem. Zool. , vol.80 , pp. 146-156
    • Malisch, J.L.1    Saltzman, W.2    Gomes, F.R.3    Rezende, E.L.4    Jeske, D.R.5    Garland, T.6
  • 63
    • 3543046113 scopus 로고    scopus 로고
    • Tumor necrosis factor (TNF)-mediated neuroprotection against glutamate-induced excitotoxicity is enhanced by N-methyl-D-aspartate receptor activation. Essential role of a TNF receptor 2-mediated phosphatidylinositol 3-kinase-dependent NF-kappa B pathway
    • Marchetti, L., Klein, M., Schlett, K., Pfizenmaier, K., Eisel, U.L., 2004. Tumor necrosis factor (TNF)-mediated neuroprotection against glutamate-induced excitotoxicity is enhanced by N-methyl-D-aspartate receptor activation. Essential role of a TNF receptor 2-mediated phosphatidylinositol 3-kinase-dependent NF-kappa B pathway. J. Biol. Chem. 279, 32869-32881. http://dx.doi.org/10.1074/jbc.M311766200.
    • (2004) J. Biol. Chem , vol.279 , pp. 32869-32881
    • Marchetti, L.1    Klein, M.2    Schlett, K.3    Pfizenmaier, K.4    Eisel, U.L.5
  • 64
    • 0027453552 scopus 로고
    • Transcription factors NF-IL6 and NF-kappa B synergistically activate transcription of the inflammatory cytokines, interleukin 6 and interleukin 8
    • Matsusaka, T., Fujikawa, K., Nishio, Y., Mukaida, N., Matsushima, K., Kishimoto, T., Akira, S., 1993. Transcription factors NF-IL6 and NF-kappa B synergistically activate transcription of the inflammatory cytokines, interleukin 6 and interleukin 8. Proc. Natl. Acad. Sci. U.S.A. 90, 10193-10197.
    • (1993) Proc. Natl. Acad. Sci. U.S.A. , vol.90 , pp. 10193-10197
    • Matsusaka, T.1    Fujikawa, K.2    Nishio, Y.3    Mukaida, N.4    Matsushima, K.5    Kishimoto, T.6    Akira, S.7
  • 65
    • 34247338117 scopus 로고    scopus 로고
    • Systemic inflammatory stimulus potentiates the acute phase and CXC chemokine responses to experimental stroke and exacerbates brain damage via interleukin-1- and neutrophil-dependent mechanisms
    • McColl, B.W., Rothwell, N.J., Allan, S.M., 2007. Systemic inflammatory stimulus potentiates the acute phase and CXC chemokine responses to experimental stroke and exacerbates brain damage via interleukin-1- and neutrophil-dependent mechanisms. J. Neurosci. 27, 4403-4412. http://dx.doi.org/10.1523/JNEUROSCI.5376-06.2007.
    • (2007) J. Neurosci. , vol.27 , pp. 4403-4412
    • McColl, B.W.1    Rothwell, N.J.2    Allan, S.M.3
  • 66
    • 33847020843 scopus 로고    scopus 로고
    • Mice with a deletion in the gene for CCAAT/enhancer-binding protein beta are protected against diet-induced obesity
    • Millward, C.A., Heaney, J.D., Sinasac, D.S., Chu, E.C., Bederman, I.R., Gilge, D.A., Previs, S.F., Croniger, C.M., 2007. Mice with a deletion in the gene for CCAAT/enhancer-binding protein beta are protected against diet-induced obesity. Diabetes 56, 161-167. http://dx.doi.org/10.2337/db06-0310.
    • (2007) Diabetes , vol.56 , pp. 161-167
    • Millward, C.A.1    Heaney, J.D.2    Sinasac, D.S.3    Chu, E.C.4    Bederman, I.R.5    Gilge, D.A.6    Previs, S.F.7    Croniger, C.M.8
  • 67
    • 0027536067 scopus 로고
    • The central role of corticotrophin-releasing factor (CRF-41) in psychological stress in rats
    • Morimoto, A., Nakamori, T., Morimoto, K., Tan, N., Murakami, N., 1993. The central role of corticotrophin-releasing factor (CRF-41) in psychological stress in rats. J. Physiol. 460, 221-229.
    • (1993) J. Physiol. , vol.460 , pp. 221-229
    • Morimoto, A.1    Nakamori, T.2    Morimoto, K.3    Tan, N.4    Murakami, N.5
  • 68
    • 0032209810 scopus 로고    scopus 로고
    • Interleukin-1beta fever in rats: gender difference and estrous cycle influence
    • Mouihate, A., Chen, X., Pittman, Q.J., 1998. Interleukin-1beta fever in rats: gender difference and estrous cycle influence. Am. J. Physiol. 275, R1450-1454.
    • (1998) Am. J. Physiol. , vol.275 , pp. R1450-R1454
    • Mouihate, A.1    Chen, X.2    Pittman, Q.J.3
  • 69
    • 0037846419 scopus 로고    scopus 로고
    • Neuroimmune response to endogenous and exogenous pyrogens is differently modulated by sex steroids
    • Mouihate, A., Pittman, Q.J., 2003. Neuroimmune response to endogenous and exogenous pyrogens is differently modulated by sex steroids. Endocrinology 144, 2454-2460. http://dx.doi.org/10.1210/en.2002-0093.
    • (2003) Endocrinology , vol.144 , pp. 2454-2460
    • Mouihate, A.1    Pittman, Q.J.2
  • 70
    • 84859563380 scopus 로고    scopus 로고
    • Kynurenines: from the perspective of major psychiatric disorders
    • Myint, A.M., 2012. Kynurenines: from the perspective of major psychiatric disorders. FEBS J. 279, 1375-1385. http://dx.doi.org/10.1111/j.1742-4658.2012.08551.x.
    • (2012) FEBS J. , vol.279 , pp. 1375-1385
    • Myint, A.M.1
  • 71
    • 84889095470 scopus 로고    scopus 로고
    • Network beyond IDO in psychiatric disorders: revisiting neurodegeneration hypothesis
    • Myint, A.M., Kim, Y.K., 2014. Network beyond IDO in psychiatric disorders: revisiting neurodegeneration hypothesis. Prog. Neuropsychopharmacol. Biol. Psychiatry 48, 304-313. http://dx.doi.org/10.1016/j.pnpbp.2013.08.008.
    • (2014) Prog. Neuropsychopharmacol. Biol. Psychiatry , vol.48 , pp. 304-313
    • Myint, A.M.1    Kim, Y.K.2
  • 72
    • 0344393076 scopus 로고    scopus 로고
    • Nuclear factor kappaB nuclear translocation as a crucial marker of brain response to interleukin-1. A study in rat and interleukin-1 type I deficient mouse
    • Nadjar, A., Combe, C., Laye, S., Tridon, V., Dantzer, R., Amedee, T., Parnet, P., 2003. Nuclear factor kappaB nuclear translocation as a crucial marker of brain response to interleukin-1. A study in rat and interleukin-1 type I deficient mouse. J. Neurochem. 87, 1024-1036.
    • (2003) J. Neurochem. , vol.87 , pp. 1024-1036
    • Nadjar, A.1    Combe, C.2    Laye, S.3    Tridon, V.4    Dantzer, R.5    Amedee, T.6    Parnet, P.7
  • 74
    • 0037146881 scopus 로고    scopus 로고
    • Effect of chronic administration of a CRF(1) receptor antagonist, CRA1000, on locomotor activity and endocrine responses to stress
    • Ohata, H., Arai, K., Shibasaki, T., 2002. Effect of chronic administration of a CRF(1) receptor antagonist, CRA1000, on locomotor activity and endocrine responses to stress. Eur. J. Pharmacol. 457, 201-206.
    • (2002) Eur. J. Pharmacol. , vol.457 , pp. 201-206
    • Ohata, H.1    Arai, K.2    Shibasaki, T.3
  • 75
    • 78149470893 scopus 로고    scopus 로고
    • Neurons and glial cells of the rat organum vasculosum laminae terminalis directly respond to lipopolysaccharide and pyrogenic cytokines
    • Ott, D., Murgott, J., Rafalzik, S., Wuchert, F., Schmalenbeck, B., Roth, J., Gerstberger, R., 2010. Neurons and glial cells of the rat organum vasculosum laminae terminalis directly respond to lipopolysaccharide and pyrogenic cytokines. Brain Res. 1363, 93-106. http://dx.doi.org/10.1016/j.brainres.2010.09.083.
    • (2010) Brain Res. , vol.1363 , pp. 93-106
    • Ott, D.1    Murgott, J.2    Rafalzik, S.3    Wuchert, F.4    Schmalenbeck, B.5    Roth, J.6    Gerstberger, R.7
  • 76
    • 84888046070 scopus 로고    scopus 로고
    • Reciprocal modulation of C/EBP-alpha and C/EBP-beta by IL-13 in activated microglia prevents neuronal death
    • Pan, H.C., Yang, C.N., Hung, Y.W., Lee, W.J., Tien, H.R., Shen, C.C., Sheehan, J., Chou, C.T., Sheu, M.L., 2013. Reciprocal modulation of C/EBP-alpha and C/EBP-beta by IL-13 in activated microglia prevents neuronal death. Eur. J. Immunol. 43, 2854-2865. http://dx.doi.org/10.1002/eji.201343301.
    • (2013) Eur. J. Immunol. , vol.43 , pp. 2854-2865
    • Pan, H.C.1    Yang, C.N.2    Hung, Y.W.3    Lee, W.J.4    Tien, H.R.5    Shen, C.C.6    Sheehan, J.7    Chou, C.T.8    Sheu, M.L.9
  • 77
    • 0003698235 scopus 로고    scopus 로고
    • The Mouse Brain in Stereotaxic Coordinates
    • Academic Press, San Diego, California, USA
    • Paxinos, G., Franklin, K.B.J., 2001. The Mouse Brain in Stereotaxic Coordinates. Academic Press, San Diego, California, USA.
    • (2001)
    • Paxinos, G.1    Franklin, K.B.J.2
  • 78
    • 84892675277 scopus 로고    scopus 로고
    • The transcription factor CCAAT enhancer-binding protein beta protects rat cerebellar granule neurons from apoptosis through its transcription-activating isoforms
    • Pena-Altamira, E., Polazzi, E., Moretto, E., Lauriola, M., Monti, B., 2014. The transcription factor CCAAT enhancer-binding protein beta protects rat cerebellar granule neurons from apoptosis through its transcription-activating isoforms. Eur. J. Neurosci. 39, 176-185. http://dx.doi.org/10.1111/ejn.12407.
    • (2014) Eur. J. Neurosci. , vol.39 , pp. 176-185
    • Pena-Altamira, E.1    Polazzi, E.2    Moretto, E.3    Lauriola, M.4    Monti, B.5
  • 79
    • 0032491401 scopus 로고    scopus 로고
    • The role of C/EBP isoforms in the control of inflammatory and native immunity functions
    • Poli, V., 1998. The role of C/EBP isoforms in the control of inflammatory and native immunity functions. J. Biol. Chem. 273, 29279-29282.
    • (1998) J. Biol. Chem. , vol.273 , pp. 29279-29282
    • Poli, V.1
  • 80
    • 0036683653 scopus 로고    scopus 로고
    • CCAAT/enhancer-binding proteins: structure, function and regulation
    • Ramji, D.P., Foka, P., 2002. CCAAT/enhancer-binding proteins: structure, function and regulation. Biochem. J. 365, 561-575. http://dx.doi.org/10.1042/BJ20020508.
    • (2002) Biochem. J. , vol.365 , pp. 561-575
    • Ramji, D.P.1    Foka, P.2
  • 81
    • 1842539535 scopus 로고    scopus 로고
    • Expressions of CCAAT-enhancer-binding proteins and c-Myc in the parotid gland of the rat: in vivo effects of isoprenaline, bethanechol, vasoactive intestinal peptide and food intake
    • Reinhold, A.C., Ekstrom, J., 2004. Expressions of CCAAT-enhancer-binding proteins and c-Myc in the parotid gland of the rat: in vivo effects of isoprenaline, bethanechol, vasoactive intestinal peptide and food intake. Arch. Oral Biol. 49, 345-354. http://dx.doi.org/10.1016/j.archoralbio.2004.01.001.
    • (2004) Arch. Oral Biol. , vol.49 , pp. 345-354
    • Reinhold, A.C.1    Ekstrom, J.2
  • 82
    • 77957751003 scopus 로고    scopus 로고
    • Involvement of nitric oxide in lipopolysaccharide induced anorexia
    • Riediger, T., Cordani, C., Potes, C.S., Lutz, T.A., 2010. Involvement of nitric oxide in lipopolysaccharide induced anorexia. Pharmacol. Biochem. Behav. 97, 112-120. http://dx.doi.org/10.1016/j.pbb.2010.04.015.
    • (2010) Pharmacol. Biochem. Behav. , vol.97 , pp. 112-120
    • Riediger, T.1    Cordani, C.2    Potes, C.S.3    Lutz, T.A.4
  • 83
    • 12144251098 scopus 로고    scopus 로고
    • The role of IFN-gamma and TNF-alpha-responsive regulatory elements in the synergistic induction of indoleamine dioxygenase
    • Robinson, C.M., Hale, P.T., Carlin, J.M., 2005. The role of IFN-gamma and TNF-alpha-responsive regulatory elements in the synergistic induction of indoleamine dioxygenase. J. Interferon Cytokine Res. 25, 20-30. http://dx.doi.org/10.1089/jir.2005.25.20.
    • (2005) J. Interferon Cytokine Res. , vol.25 , pp. 20-30
    • Robinson, C.M.1    Hale, P.T.2    Carlin, J.M.3
  • 84
    • 84919402914 scopus 로고    scopus 로고
    • Mechanisms of fever production and lysis: lessons from experimental LPS fever
    • Roth, J., Blatteis, C.M., 2014. Mechanisms of fever production and lysis: lessons from experimental LPS fever. Compr. Physiol. 4, 1563-1604. http://dx.doi.org/10.1002/cphy.c130033.
    • (2014) Compr. Physiol. , vol.4 , pp. 1563-1604
    • Roth, J.1    Blatteis, C.M.2
  • 85
    • 2542466803 scopus 로고    scopus 로고
    • Signaling the brain in systemic inflammation: role of sensory circumventricular organs
    • Roth, J., Harre, E.M., Rummel, C., Gerstberger, R., Hubschle, T., 2004. Signaling the brain in systemic inflammation: role of sensory circumventricular organs. Front. Biosci. 9, 290-300.
    • (2004) Front. Biosci. , vol.9 , pp. 290-300
    • Roth, J.1    Harre, E.M.2    Rummel, C.3    Gerstberger, R.4    Hubschle, T.5
  • 87
    • 27144545768 scopus 로고    scopus 로고
    • Thermoregulatory responses to lipopolysaccharide in the mouse: dependence on the dose and ambient temperature
    • Rudaya, A.Y., Steiner, A.A., Robbins, J.R., Dragic, A.S., Romanovsky, A.A., 2005. Thermoregulatory responses to lipopolysaccharide in the mouse: dependence on the dose and ambient temperature. Am. J. Physiol. Regul. Integr. Comp. Physiol. 289, R1244-1252. http://dx.doi.org/10.1152/ajpregu.00370.2005.
    • (2005) Am. J. Physiol. Regul. Integr. Comp. Physiol. , vol.289 , pp. R1244-R1252
    • Rudaya, A.Y.1    Steiner, A.A.2    Robbins, J.R.3    Dragic, A.S.4    Romanovsky, A.A.5
  • 88
    • 77951877918 scopus 로고    scopus 로고
    • Leptin regulates leukocyte recruitment into the brain following systemic LPS-induced inflammation.
    • Rummel, C., Inoue, W., Poole, S., Luheshi, G.N., 2010. Leptin regulates leukocyte recruitment into the brain following systemic LPS-induced inflammation. Mol. Psychiatry 15, 523-534. http://dx.doi.org/10.1038/mp.2009.98.
    • (2010) Mol. Psychiatry , vol.15 , pp. 523-534
    • Rummel, C.1    Inoue, W.2    Poole, S.3    Luheshi, G.N.4
  • 89
    • 58149147511 scopus 로고    scopus 로고
    • Selective contribution of interleukin-6 and leptin to brain inflammatory signals induced by systemic LPS injection in mice
    • Rummel, C., Inoue, W., Sachot, C., Poole, S., Hubschle, T., Luheshi, G.N., 2008. Selective contribution of interleukin-6 and leptin to brain inflammatory signals induced by systemic LPS injection in mice. J. Comp. Neurol. 511, 373-395. http://dx.doi.org/10.1002/cne.21850.
    • (2008) J. Comp. Neurol. , vol.511 , pp. 373-395
    • Rummel, C.1    Inoue, W.2    Sachot, C.3    Poole, S.4    Hubschle, T.5    Luheshi, G.N.6
  • 90
    • 82755160605 scopus 로고    scopus 로고
    • Circulating IL-6 contributes to peripheral LPS-induced mPGES-1 expression in the rat brain
    • Rummel, C., Matsumura, K., Luheshi, G.N., 2011. Circulating IL-6 contributes to peripheral LPS-induced mPGES-1 expression in the rat brain. Brain Res. Bull. 86, 319-325. http://dx.doi.org/10.1016/j.brainresbull.2011.09.006.
    • (2011) Brain Res. Bull. , vol.86 , pp. 319-325
    • Rummel, C.1    Matsumura, K.2    Luheshi, G.N.3
  • 91
    • 33751192075 scopus 로고    scopus 로고
    • Circulating interleukin-6 induces fever through a STAT3-linked activation of COX-2 in the brain
    • Rummel, C., Sachot, C., Poole, S., Luheshi, G.N., 2006. Circulating interleukin-6 induces fever through a STAT3-linked activation of COX-2 in the brain. Am. J. Physiol. Regul. Integr. Comp. Physiol. 291, R1316-1326. http://dx.doi.org/10.1152/ajpregu.00301.2006.
    • (2006) Am. J. Physiol. Regul. Integr. Comp. Physiol. , vol.291 , pp. R1316-R1326
    • Rummel, C.1    Sachot, C.2    Poole, S.3    Luheshi, G.N.4
  • 92
    • 24344501250 scopus 로고    scopus 로고
    • Nuclear STAT3 translocation in guinea pig and rat brain endothelium during systemic challenge with lipopolysaccharide and interleukin-6
    • Rummel, C., Voss, T., Matsumura, K., Korte, S., Gerstberger, R., Roth, J., Hubschle, T., 2005. Nuclear STAT3 translocation in guinea pig and rat brain endothelium during systemic challenge with lipopolysaccharide and interleukin-6. J. Comp. Neurol. 491, 1-14. http://dx.doi.org/10.1002/cne.20653.
    • (2005) J. Comp. Neurol. , vol.491 , pp. 1-14
    • Rummel, C.1    Voss, T.2    Matsumura, K.3    Korte, S.4    Gerstberger, R.5    Roth, J.6    Hubschle, T.7
  • 93
    • 17844390365 scopus 로고    scopus 로고
    • Impaired febrile responses to immune challenge in mice deficient in microsomal prostaglandin E synthase-1
    • Saha, S., Engstrom, L., Mackerlova, L., Jakobsson, P.J., Blomqvist, A., 2005. Impaired febrile responses to immune challenge in mice deficient in microsomal prostaglandin E synthase-1. Am. J. Physiol. Regul. Integr. Comp. Physiol. 288, R1100-1107. http://dx.doi.org/10.1152/ajpregu.00872.2004.
    • (2005) Am. J. Physiol. Regul. Integr. Comp. Physiol. , vol.288 , pp. R1100-R1107
    • Saha, S.1    Engstrom, L.2    Mackerlova, L.3    Jakobsson, P.J.4    Blomqvist, A.5
  • 94
    • 79952535268 scopus 로고    scopus 로고
    • Sex- and age-specific differences in core body temperature of C57Bl/6 mice
    • Sanchez-Alavez, M., Alboni, S., Conti, B., 2011. Sex- and age-specific differences in core body temperature of C57Bl/6 mice. Age (Dordr) 33, 89-99. http://dx.doi.org/10.1007/s11357-010-9164-6.
    • (2011) Age (Dordr) , vol.33 , pp. 89-99
    • Sanchez-Alavez, M.1    Alboni, S.2    Conti, B.3
  • 95
    • 84864484031 scopus 로고    scopus 로고
    • Neural circuitry engaged by prostaglandins during the sickness syndrome
    • Saper, C.B., Romanovsky, A.A., Scammell, T.E., 2012. Neural circuitry engaged by prostaglandins during the sickness syndrome. Nat. Neurosci. 15, 1088-1095. http://dx.doi.org/10.1038/nn.3159.
    • (2012) Nat. Neurosci. , vol.15 , pp. 1088-1095
    • Saper, C.B.1    Romanovsky, A.A.2    Scammell, T.E.3
  • 96
    • 3142687010 scopus 로고    scopus 로고
    • Signaling the brain in systemic inflammation: the role of perivascular cells
    • Schiltz, J.C., Sawchenko, P.E., 2003. Signaling the brain in systemic inflammation: the role of perivascular cells. Front. Biosci. 8, s1321-1329.
    • (2003) Front. Biosci. , vol.8 , pp. s1321-s1329
    • Schiltz, J.C.1    Sawchenko, P.E.2
  • 97
    • 0033527549 scopus 로고    scopus 로고
    • Interleukin-10 signaling blocks inhibitor of kappaB kinase activity and nuclear factor kappaB DNA binding
    • Schottelius, A.J., Mayo, M.W., Sartor, R.B., Baldwin Jr., A.S., 1999. Interleukin-10 signaling blocks inhibitor of kappaB kinase activity and nuclear factor kappaB DNA binding. J. Biol. Chem. 274, 31868-31874.
    • (1999) J. Biol. Chem. , vol.274 , pp. 31868-31874
    • Schottelius, A.J.1    Mayo, M.W.2    Sartor, R.B.3    Baldwin, A.S.4
  • 99
    • 84922575896 scopus 로고    scopus 로고
    • Lipid Mediators in the Resolution of Inflammation
    • Cold Spring Harb. Perspect Biol
    • Serhan, C.N., Chiang, N., Dalli, J., Levy, B.D., 2014. Lipid Mediators in the Resolution of Inflammation. Cold Spring Harb. Perspect Biol. http://dx.doi.org/10.1101/cshperspect.a016311.
    • (2014)
    • Serhan, C.N.1    Chiang, N.2    Dalli, J.3    Levy, B.D.4
  • 100
    • 73549117185 scopus 로고    scopus 로고
    • Dual roles for perivascular macrophages in immune-to-brain signaling
    • Serrats, J., Schiltz, J.C., Garcia-Bueno, B., van Rooijen, N., Reyes, T.M., Sawchenko, P.E., 2010. Dual roles for perivascular macrophages in immune-to-brain signaling. Neuron 65, 94-106. http://dx.doi.org/10.1016/j.neuron.2009.11.032.
    • (2010) Neuron , vol.65 , pp. 94-106
    • Serrats, J.1    Schiltz, J.C.2    Garcia-Bueno, B.3    van Rooijen, N.4    Reyes, T.M.5    Sawchenko, P.E.6
  • 101
    • 30044435949 scopus 로고    scopus 로고
    • SERT-ainly involved in depression, but when?
    • Sibille, E., Lewis, D.A., 2006. SERT-ainly involved in depression, but when? Am. J. Psychiatry 163, 8-11. http://dx.doi.org/10.1176/appi.ajp.163.1.8.
    • (2006) Am. J. Psychiatry , vol.163 , pp. 8-11
    • Sibille, E.1    Lewis, D.A.2
  • 103
    • 84882870599 scopus 로고    scopus 로고
    • CCAAT/enhancer binding protein beta regulates prostaglandin E synthase expression and prostaglandin E2 production in activated microglial cells
    • Straccia, M., Dentesano, G., Valente, T., Pulido-Salgado, M., Sola, C., Saura, J., 2013. CCAAT/enhancer binding protein beta regulates prostaglandin E synthase expression and prostaglandin E2 production in activated microglial cells. Glia 61, 1607-1619. http://dx.doi.org/10.1002/glia.22542.
    • (2013) Glia , vol.61 , pp. 1607-1619
    • Straccia, M.1    Dentesano, G.2    Valente, T.3    Pulido-Salgado, M.4    Sola, C.5    Saura, J.6
  • 104
    • 84899583984 scopus 로고    scopus 로고
    • CCAAT-enhancer binding protein-beta expression and elevation in Alzheimer's disease and microglial cell cultures
    • Strohmeyer, R., Shelton, J., Lougheed, C., Breitkopf, T., 2014. CCAAT-enhancer binding protein-beta expression and elevation in Alzheimer's disease and microglial cell cultures. PLoS One 9, e86617. http://dx.doi.org/10.1371/journal.pone.0086617.
    • (2014) PLoS One , vol.9
    • Strohmeyer, R.1    Shelton, J.2    Lougheed, C.3    Breitkopf, T.4
  • 105
    • 79952477473 scopus 로고    scopus 로고
    • PACAP: a master regulator of neuroendocrine stress circuits and the cellular stress response
    • Stroth, N., Holighaus, Y., Ait-Ali, D., Eiden, L.E., 2011. PACAP: a master regulator of neuroendocrine stress circuits and the cellular stress response. Ann. N. Y. Acad. Sci. 1220, 49-59. http://dx.doi.org/10.1111/j.1749-6632.2011.05904.x.
    • (2011) Ann. N. Y. Acad. Sci. , vol.1220 , pp. 49-59
    • Stroth, N.1    Holighaus, Y.2    Ait-Ali, D.3    Eiden, L.E.4
  • 106
    • 0034928798 scopus 로고    scopus 로고
    • The consolidation of new but not reactivated memory requires hippocampal C/EBPbeta
    • Taubenfeld, S.M., Milekic, M.H., Monti, B., Alberini, C.M., 2001. The consolidation of new but not reactivated memory requires hippocampal C/EBPbeta. Nat. Neurosci. 4, 813-818. http://dx.doi.org/10.1038/90520.
    • (2001) Nat. Neurosci. , vol.4 , pp. 813-818
    • Taubenfeld, S.M.1    Milekic, M.H.2    Monti, B.3    Alberini, C.M.4
  • 107
    • 0033825851 scopus 로고    scopus 로고
    • The role of tumor necrosis factor (TNF) in the febrile and metabolic responses of rats to intraperitoneal injection of a high dose of lipopolysaccharide
    • Tollner, B., Roth, J., Storr, B., Martin, D., Voigt, K., Zeisberger, E., 2000. The role of tumor necrosis factor (TNF) in the febrile and metabolic responses of rats to intraperitoneal injection of a high dose of lipopolysaccharide. Pflugers Arch. 440, 925-932.
    • (2000) Pflugers Arch. , vol.440 , pp. 925-932
    • Tollner, B.1    Roth, J.2    Storr, B.3    Martin, D.4    Voigt, K.5    Zeisberger, E.6
  • 108
    • 0032078995 scopus 로고    scopus 로고
    • Mechanisms of hypothalamic-pituitary-adrenal axis stimulation by immune signals in the adult rat
    • Turnbull, A.V., Lee, S., Rivier, C., 1998. Mechanisms of hypothalamic-pituitary-adrenal axis stimulation by immune signals in the adult rat. Ann. N. Y. Acad. Sci. 840, 434-443.
    • (1998) Ann. N. Y. Acad. Sci. , vol.840 , pp. 434-443
    • Turnbull, A.V.1    Lee, S.2    Rivier, C.3
  • 110
    • 0036604215 scopus 로고    scopus 로고
    • Lipopolysaccharide-dependent prostaglandin E(2) production is regulated by the glutathione-dependent prostaglandin E(2) synthase gene induced by the Toll-like receptor 4/MyD88/NF-IL6 pathway
    • Uematsu, S., Matsumoto, M., Takeda, K., Akira, S., 2002. Lipopolysaccharide-dependent prostaglandin E(2) production is regulated by the glutathione-dependent prostaglandin E(2) synthase gene induced by the Toll-like receptor 4/MyD88/NF-IL6 pathway. J. Immunol. 168, 5811-5816.
    • (2002) J. Immunol. , vol.168 , pp. 5811-5816
    • Uematsu, S.1    Matsumoto, M.2    Takeda, K.3    Akira, S.4
  • 111
    • 84907901414 scopus 로고    scopus 로고
    • Long-term corticosterone exposure decreases insulin sensitivity and induces depressive-like behaviour in the C57BL/6NCrl mouse
    • van Donkelaar, E.L., Vaessen, K.R., Pawluski, J.L., Sierksma, A.S., Blokland, A., Canete, R., Steinbusch, H.W., 2014. Long-term corticosterone exposure decreases insulin sensitivity and induces depressive-like behaviour in the C57BL/6NCrl mouse. PLoS One 9, e106960. http://dx.doi.org/10.1371/journal.pone.0106960.
    • (2014) PLoS One , vol.9
    • van Donkelaar, E.L.1    Vaessen, K.R.2    Pawluski, J.L.3    Sierksma, A.S.4    Blokland, A.5    Canete, R.6    Steinbusch, H.W.7
  • 112
    • 84861808931 scopus 로고    scopus 로고
    • Fever induction by systemic stimulation with macrophage-activating lipopeptide-2 depends upon TLR2 but not CD36
    • Welsch, J., Hubschle, T., Murgott, J., Kirschning, C., Rummel, C., Gerstberger, R., Roth, J., 2012. Fever induction by systemic stimulation with macrophage-activating lipopeptide-2 depends upon TLR2 but not CD36. Innate Immun. 18, 541-559. http://dx.doi.org/10.1177/1753425911426892.
    • (2012) Innate Immun. , vol.18 , pp. 541-559
    • Welsch, J.1    Hubschle, T.2    Murgott, J.3    Kirschning, C.4    Rummel, C.5    Gerstberger, R.6    Roth, J.7
  • 114
    • 54349099665 scopus 로고    scopus 로고
    • Rat area postrema microglial cells act as sensors for the toll-like receptor-4 agonist lipopolysaccharide
    • Wuchert, F., Ott, D., Murgott, J., Rafalzik, S., Hitzel, N., Roth, J., Gerstberger, R., 2008. Rat area postrema microglial cells act as sensors for the toll-like receptor-4 agonist lipopolysaccharide. J. Neuroimmunol. 204, 66-74. http://dx.doi.org/10.1016/j.jneuroim.2008.07.017.
    • (2008) J. Neuroimmunol. , vol.204 , pp. 66-74
    • Wuchert, F.1    Ott, D.2    Murgott, J.3    Rafalzik, S.4    Hitzel, N.5    Roth, J.6    Gerstberger, R.7
  • 115
    • 58149234819 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha, interleukin-1beta and nitric oxide induce calcium transients in distinct populations of cells cultured from the rat area postrema
    • Wuchert, F., Ott, D., Rafalzik, S., Roth, J., Gerstberger, R., 2009. Tumor necrosis factor-alpha, interleukin-1beta and nitric oxide induce calcium transients in distinct populations of cells cultured from the rat area postrema. J. Neuroimmunol. 206, 44-51. http://dx.doi.org/10.1016/j.jneuroim.2008.10.010.
    • (2009) J. Neuroimmunol. , vol.206 , pp. 44-51
    • Wuchert, F.1    Ott, D.2    Rafalzik, S.3    Roth, J.4    Gerstberger, R.5
  • 117
    • 65349107367 scopus 로고    scopus 로고
    • CCAAT/enhancer-binding protein beta: its role in breast cancer and associations with receptor tyrosine kinases
    • Zahnow, C.A., 2009. CCAAT/enhancer-binding protein beta: its role in breast cancer and associations with receptor tyrosine kinases. Expert Rev. Mol. Med. 11, e12. http://dx.doi.org/10.1017/S1462399409001033.
    • (2009) Expert Rev. Mol. Med. , vol.11
    • Zahnow, C.A.1
  • 118
    • 84926466569 scopus 로고    scopus 로고
    • Inhibition of serotonin transporter expression by C/EBPbeta in LPS-activated macrophage cells (HD11)
    • Zimmermann, K., van Phi, V.D., Brase, A., Phi-van, L., 2014. Inhibition of serotonin transporter expression by C/EBPbeta in LPS-activated macrophage cells (HD11). Innate Immun. http://dx.doi.org/10.1177/1753425914547434.
    • (2014) Innate Immun
    • Zimmermann, K.1    van Phi, V.D.2    Brase, A.3    Phi-van, L.4


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