Gender-dependent alterations in corticosteroid receptor status and spatial performance following 21 days of restraint stress

Neuroscience

Volumn 125, Issue 1, 2004, Pages 47-55

  Kitraki, E ^a   Kremmyda, O ^a   Youlatos, D ^b   Alexis, Michael N ^c   Kittas, C ^a  

^a UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

^b ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

^c INSTITUTE OF BIOLOGY   (Greece)

Author keywords

CA; Cornu ammonis; Dentate gyrus; DG; Glucocorticoid receptor; GR; Hippocampus; HPA; Hypothalamic pituitary adrenal; Immunohistochemistry; Least significant difference; LSD; Mineralocorticoid receptor; MR; PBS; Sex differences; Water maze

Indexed keywords

CORTICOSTEROID RECEPTOR; GLUCOCORTICOID RECEPTOR; MINERALOCORTICOID RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; CONTROLLED STUDY; DENTATE GYRUS; FEMALE; GENDER; HIPPOCAMPUS; IMMOBILIZATION STRESS; IMMUNOREACTIVITY; LEARNING; MALE; MAZE TEST; MENTAL TASK; NONHUMAN; PRIORITY JOURNAL; RAT; SCORING SYSTEM; SEX DIFFERENCE; SPATIAL MEMORY;

EID: 1642544092     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2003.12.024     Document Type: Article

References (37)

1. Ahima R.S., Lawson A.N., Osei S.Y., Harlan R.E. Sexual dimorphism in regulation of type II corticosteroid receptor immunoreactivity in the rat hippocampus. Endocrinology. 131:1992;1409-1416.
2. Almeida O.F., Conde G.L., Crochemore C., Demeneix B.A., Fischer D., Hassan A.H., Meyer M., Holsboer F., Michaelidis T.M. Subtle shifts in the ratio between pro- and antiapoptotic molecules after activation of corticosteroid receptors decide neuronal fate. FASEB J. 14:2000;779-790.
3. Cole M.A., Kalman B.A., Pace T.W., Topczewski F., Lowrey M.J., Spencer R.L. Selective blockade of the mineralocorticoid receptor impairs hypothalamic-pituitary-adrenal axis expression of habituation. J Neuroendocrinol. 12:2000;1034-1042.
4. Conrad C.D., Galea L.A., Kuroda Y., McEwen B.S. Chronic stress impairs rat spatial memory on the Y maze, and this effect is blocked by tianeptine pretreatment. Behav Neurosci. 110:1996;1321-1334.
5. Conrad C.D., Grote K.A., Hobbs R.J., Ferayorni A. Sex differences in spatial and non-spatial Y-maze performance after chronic stress. Neurobiol Learn Mem. 79:2003;32-40.
6. de Kloet E.R., Oitzl M.S., Joels M. Stress and cognition Are corticosteroids good or bad guys? Trends Neurosci. 22:1999;422-426.
7. de Kloet E.R., Vreugdenhil E., Oitzl M.S., Joels M. Brain corticosteroid receptor balance in health and disease. Endocr Rev. 19:1998;269-301.
8. Einon D. Spatial memory and response strategies in rats Age, sex and rearing differences in performance. Q J Exp Psychol. 32:1980;473-489.
9. Frye C.A. Estrus-associated decrements in a water maze task are limited to acquisition. Physiol Behav. 57:1995;5-14.
10. Galea L.A., McEwen B.S., Tanapat P., Deak T., Spencer R.L., Dhabhar F.S. Sex differences in dendritic atrophy of CA3 pyramidal neurons in response to chronic restraint stress. Neuroscience. 81:1997;689-697.
11. Gass P., Kretz O., Wolfer D.P., Berger S., Tronche F., Reichardt H.M., Kellendonk C., Lipp H.P., Schmid W., Schutz G. Genetic disruption of mineralocorticoid receptor leads to impaired neurogenesis and granule cell degeneration in the hippocampus of adult mice. EMBO Rep. 1:2000;447-451.
12. Gomez F., Lahmame A., de Kloet E.R., Armario A. Hypothalamic-pituitary- adrenal response to chronic stress in five inbred rat strains Differential responses are mainly located at the adrenocortical level. Neuroendocrinology. 63:1996;327-337.
13. Herman J.P., Adams D., Prewitt C. Regulatory changes in neuroendocrine stress-integrative circuitry produced by a variable stress paradigm. Neuroendocrinology. 61:1995;180-190.
14. Karandrea D., Kittas C., Kitraki E. Contribution of sex and cellular context in the regulation of brain corticosteroid receptors following restraint stress. Neuroendocrinology. 71:2000;343-353.
15. Karandrea D., Kittas C., Kitraki E. Forced swimming differentially affects male and female brain corticosteroid receptors. Neuroendocrinology. 75:2002;217-226.
16. Kitraki E., Karandrea D., Kittas C. Long-lasting effects of stress on glucocorticoid receptor gene expression in the rat brain. Neuroendocrinology. 69:1999;331-338.
17. Luine V., Villegas M., Martinez C., McEwen B.S. Repeated stress causes reversible impairments of spatial memory performance. Brain Res. 639:1994;167-170.
18. Luine V., Martinez C., Villegas M., Magarinos A.M., McEwen B.S. Restraint stress reversibly enhances spatial memory performance. Physiol Behav. 59:1996;27-32.
19. Lupien S.J., Lepage M. Stress, memory, and the hippocampus Can't live with it, can't live without it. Behav Brain Res. 127:2001;137-158.
20. Magarinos A.M., McEwen B.S. Stress-induced atrophy of apical dendrites of hippocampal CA3c neurons Involvement of glucocorticoid secretion and excitatory amino acid receptors. Neuroscience. 69:1995;89-98.
21. Magarinos A.M., McEwen B.S., Flugge G., Fuchs E. Chronic psychosocial stress causes apical dendritic atrophy of hippocampal CA3 pyramidal neurons in subordinate tree shrews. J Neurosci. 16:1996;3534-3540.
22. Makino S., Smith M.A., Gold P.W. Increased expression of corticotropin-releasing hormone and vasopressin messenger ribonucleic acid (mRNA) in the hypothalamic paraventricular nucleus during repeated stress Association with reduction in glucocorticoid receptor mrna levels. Endocrinology. 136:1995;3299-3309.
23. McEwen B.S. Stress and hippocampal plasticity. Annu Rev Neurosci. 22:1999;105-122.
24. McEwen B.S. The neurobiology of stress From serendipity to clinical relevance. Brain Res. 886:2000;172-189.
25. Oitzl M.S., de Kloet E.R. Selective corticosteroid antagonists modulate specific aspects of spatial orientation learning. Behav Neurosci. 106:1992;62-71.
26. Oitzl M.S., Reichardt H.M., Joels M., de Kloet E.R. Point mutation in the mouse glucocorticoid receptor preventing DNA binding impairs spatial memory. Proc Natl Acad Sci USA. 98:2001;12790-12795.
27. Oitzl M.S., de Kloet E.R., Joels M., Schmid W., Cole T.J. Spatial learning deficits in mice with a targeted glucocorticoid receptor gene disruption. Eur J Neurosci. 9:1997;2284-2296.
28. Paxinos G, Watson C (1998) The rat brain in stereotaxic coordinates, 4th edition. San Diego, CA: Academic Press.
29. Pham K., Nacher J., Hof P.R., McEwen B.S. Repeated restraint stress suppresses neurogenesis and induces biphasic PSA-NCAM expression in the adult rat dentate gyrus. Eur J Neurosci. 17:2003;879-886.
30. Roof R.L., Havens M.D. Testosterone improves maze performance and induces development of a male hippocampus in females. Brain Res. 572:1992;310-313.
31. Roof R.L., Stein D.G. Gender differences in Morris water maze performance depend on task parameters. Physiol Behav. 68:1999;81-86.
32. Sapolsky R.M., Krey L.C., McEwen B.S. Stress down-regulates corticosterone receptors in a site-specific manner in the brain. Endocrinology. 114:1984;287-292.
33. Siriani D., Mitsiou D.J., Alexis M.N. Overexpressed glucocorticoid receptor negatively regulates gene expression under conditions that favour accumulation of non-hormone-binding forms of the receptor. J Steroid Biochem Mol Biol. 84:2003;171-180.
34. Sousa N., Lukoyanov N.V., Madeira M.D., Almeida O.F., Paula-Barbosa M.M. Reorganization of the morphology of hippocampal neurites and synapses after stress-induced damage correlates with behavioral improvement. Neuroscience. 97:2000;253-266.
35. van Haaren F., Wouters M., van de Poll N.E. Absence of behavioral differences between male and female rats in different radial-maze procedures. Physiol Behav. 39:1987;409-412.
36. Venero C., Tilling T., Hermans-Borgmeyer I., Schmidt R., Schachner M., Sandi C. Chronic stress induces opposite changes in the mRNA expression of the cell adhesion molecules NCAM and L1. Neuroscience. 115:2002;1211-1219.
37. Williams C.L., Barnett A.M., Meck W.H. Organizational effects of early gonadal secretions on sexual differentiation in spatial memory. Behav Neurosci. 104:1990;84-97.