In vivo deficiency of both C/EBPβ and C/EBP results in highly defective myeloid differentiation and lack of cytokine response

PLoS ONE

Volumn 5, Issue 11, 2010, Pages

  Akagi, Tadayuki ^a,e   Thoennissen, Nils H ^a   George, Ann ^b   Crooks, Gay ^a   Song, Jee Hoon ^a   Okamoto, Ryoko ^a   Nowak, Daniel ^a   Gombart, Adrian F ^c   Phillip Koeffler, H ^a,d  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b CHILDREN S HOSPITAL LOS ANGELES   (United States)

^c OREGON STATE UNIVERSITY   (United States)

^d NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^e KANAZAWA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN BETA; CCAAT ENHANCER BINDING PROTEIN EPSILON; CD38 ANTIGEN; CELL PROTEIN; CYTOKINE; GAMMA INTERFERON; LIPOPOLYSACCHARIDE; MACROPHAGE MANNOSE RECEPTOR; MACROPHAGE RECEPTOR WITH COLLAGENOUS STRUCTURE; MANNOSE RECEPTOR; SUPPRESSOR OF CYTOKINE SIGNALING 2; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; CCAAT ENHANCER BINDING PROTEIN; CEBPE PROTEIN, MOUSE; IMMUNOGLOBULIN RECEPTOR; MARCO PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BIOACCUMULATION; BONE MARROW CELL; CELL COMPARTMENTALIZATION; CELL DIFFERENTIATION; CELL MATURATION; CONTROLLED STUDY; CYTOKINE RESPONSE; GENE EXPRESSION PROFILING; HEMATOPOIETIC STEM CELL; IMMUNE RESPONSE; IN VIVO STUDY; MACROPHAGE; MOUSE; NEUTROPHIL; NEWBORN; NONHUMAN; PHENOTYPE; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN MICROARRAY; SIGNAL TRANSDUCTION; SPECIES DIFFERENCE; WILD ANIMAL; 129 MOUSE; ANIMAL; BACTERIAL INFECTION; CLUSTER ANALYSIS; CYTOLOGY; DNA MICROARRAY; DRUG EFFECT; FEMALE; GENE REGULATORY NETWORK; GENETICS; MALE; METABOLISM; MICROBIOLOGY; MOUSE MUTANT; PRENATAL DEVELOPMENT; PROTEIN BINDING; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

MUS;

ANIMALS; ANIMALS, NEWBORN; BACTERIAL INFECTIONS; BLOTTING, WESTERN; CCAAT-ENHANCER-BINDING PROTEIN-BETA; CCAAT-ENHANCER-BINDING PROTEINS; CELL DIFFERENTIATION; CLUSTER ANALYSIS; CYTOKINES; FEMALE; GENE EXPRESSION PROFILING; GENE REGULATORY NETWORKS; INTERFERON-GAMMA; LIPOPOLYSACCHARIDES; MACROPHAGES; MALE; MICE; MICE, 129 STRAIN; MICE, KNOCKOUT; NEUTROPHILS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; RECEPTORS, IMMUNOLOGIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 78149484622     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0015419     Document Type: Article

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