메뉴 건너뛰기




Volumn 1220, Issue 1, 2011, Pages 49-59

PACAP: A master regulator of neuroendocrine stress circuits and the cellular stress response

Author keywords

HPA axis; Hypothalamus; Neuropeptides; PACAP; Stress response

Indexed keywords

ADRENALIN; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; GENE PRODUCT; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE; MESSENGER RNA; NEUROPEPTIDE; NEUROTRANSMITTER;

EID: 79952477473     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2011.05904.x     Document Type: Article
Times cited : (99)

References (64)
  • 1
    • 15744391563 scopus 로고    scopus 로고
    • Handbook of Cell Signaling
    • In R. Bradshaw & E. Dennis, Eds. Academic Press. New York
    • Eiden, L.E. 2003. Signaling during exocytosis. In Handbook of Cell Signaling. Vol. 3. R. Bradshaw & E. Dennis, Eds.: 375-392. Academic Press. New York
    • (2003) Signaling during exocytosis , vol.3 , pp. 375-392
    • Eiden, L.E.1
  • 2
    • 0038714965 scopus 로고    scopus 로고
    • Neuropeptides: opportunities for drug discovery
    • Hökfelt, T., T. Bartfai & F. Bloom 2003. Neuropeptides: opportunities for drug discovery. Lancet Neurol. 2: 463-472.
    • (2003) Lancet Neurol. , vol.2 , pp. 463-472
    • Hökfelt, T.1    Bartfai, T.2    Bloom, F.3
  • 3
    • 0024415355 scopus 로고
    • Isolation of a novel 38 residue-hypothalamic polypeptide which stimulates adenylate cyclase in pituitary cells
    • Miyata, A. et al 1989. Isolation of a novel 38 residue-hypothalamic polypeptide which stimulates adenylate cyclase in pituitary cells. Biochem. Biophys. Res. Commun. 164: 567-574.
    • (1989) Biochem. Biophys. Res. Commun. , vol.164 , pp. 567-574
    • Miyata, A.1
  • 4
    • 34447628199 scopus 로고    scopus 로고
    • Handbook of Neurochemistry and Molecular Neurobiology: XIII. Neuroactive Peptides and Proteins
    • In R. Lim, Ed. Springer. Heidelberg
    • Mustafa, T. & L.E. Eiden 2006. The secretin superfamily: PACAP, VIP and related peptides. In Handbook of Neurochemistry and Molecular Neurobiology: XIII. Neuroactive Peptides and Proteins. Vol. XIII. R. Lim, Ed.: 1-36. Springer. Heidelberg
    • (2006) The secretin superfamily: PACAP, VIP and related peptides , vol.13 , pp. 1-36
    • Mustafa, T.1    Eiden, L.E.2
  • 5
    • 0035400123 scopus 로고    scopus 로고
    • Pituitary adenylyl cyclase-activating peptides and alpha-amidation in olfactory neurogenesis and neuronal survival in vitro
    • Hansel, D.E. et al 2001. Pituitary adenylyl cyclase-activating peptides and alpha-amidation in olfactory neurogenesis and neuronal survival in vitro. J. Neurosci. 21: 4625-4636.
    • (2001) J. Neurosci. , vol.21 , pp. 4625-4636
    • Hansel, D.E.1
  • 6
    • 43049141452 scopus 로고    scopus 로고
    • The activation and physiological functions of the proprotein convertases
    • Seidah, N.G. et al 2008. The activation and physiological functions of the proprotein convertases. Int. J. Biochem. Cell Biol. 40: 1111-1125.
    • (2008) Int. J. Biochem. Cell Biol. , vol.40 , pp. 1111-1125
    • Seidah, N.G.1
  • 7
    • 0033735478 scopus 로고    scopus 로고
    • Pituitary adenylate cyclase-activating polypeptide precursor is processed solely by prohormone convertase 4 in the gonads
    • Li, M., M. Mbikay & A. Arimura 2000. Pituitary adenylate cyclase-activating polypeptide precursor is processed solely by prohormone convertase 4 in the gonads. Endocrinology 141: 3723-3730.
    • (2000) Endocrinology , vol.141 , pp. 3723-3730
    • Li, M.1    Mbikay, M.2    Arimura, A.3
  • 8
    • 0029056734 scopus 로고
    • A neuropeptide gene defined by the Drosophila memory mutant amnesiac
    • Feany, M.B. & W.G. Quinn 1995. A neuropeptide gene defined by the Drosophila memory mutant amnesiac. Science 268: 869-873.
    • (1995) Science , vol.268 , pp. 869-873
    • Feany, M.B.1    Quinn, W.G.2
  • 9
    • 0029056754 scopus 로고
    • Mediation of PACAP-like neuropeptide transmission by coactivation of Ras/Raf and cAMP signal transduction pathways in Drosophila
    • Zhong, Y. 1995. Mediation of PACAP-like neuropeptide transmission by coactivation of Ras/Raf and cAMP signal transduction pathways in Drosophila. Nature 375: 588-592.
    • (1995) Nature , vol.375 , pp. 588-592
    • Zhong, Y.1
  • 10
    • 0032442307 scopus 로고    scopus 로고
    • The PACAP ligand/receptor system regulates cerebral cortical neurogenesis
    • DiCicco-Bloom, E. et al 1998. The PACAP ligand/receptor system regulates cerebral cortical neurogenesis. Ann. N.Y. Acad. Sci. 865: 274-289.
    • (1998) Ann. N.Y. Acad. Sci. , vol.865 , pp. 274-289
    • Dicicco-Bloom, E.1
  • 11
    • 0035901719 scopus 로고    scopus 로고
    • BDNF mediates the neuroprotective effect of PACAP-38 on rat cortical neurons
    • Frechilla, D. et al 2001. BDNF mediates the neuroprotective effect of PACAP-38 on rat cortical neurons. Neuroreport 12: 919-923.
    • (2001) Neuroreport , vol.12 , pp. 919-923
    • Frechilla, D.1
  • 12
    • 1842862736 scopus 로고    scopus 로고
    • PACAP promotes sensory neuron differentiation: blockade by neurotrophic factors
    • Nielsen, K.M. et al 2004. PACAP promotes sensory neuron differentiation: blockade by neurotrophic factors. Molec. Cell. Neurosci. 25: 629-641.
    • (2004) Molec. Cell. Neurosci. , vol.25 , pp. 629-641
    • Nielsen, K.M.1
  • 13
    • 0032562177 scopus 로고    scopus 로고
    • Pituitary adenylate cyclase-activating polypeptide stimulates both c-Fos gene expression and cell survival in rat cerebellar granule neurons through activation of the protein kinase A pathway
    • Vaudry, D. et al 1998. Pituitary adenylate cyclase-activating polypeptide stimulates both c-Fos gene expression and cell survival in rat cerebellar granule neurons through activation of the protein kinase A pathway. Neuroscience 84: 801-812.
    • (1998) Neuroscience , vol.84 , pp. 801-812
    • Vaudry, D.1
  • 14
    • 77951223899 scopus 로고    scopus 로고
    • Pituitary adenylate cyclase-activating polypeptide (PACAP)/PAC1HOP1 receptor activation coordinates multiple neurotrophic signaling pathways: Akt activation through phosphatidylinositol 3-kinase gamma and vesicle endocytosis for neuronal survival
    • May, V. et al 2010. Pituitary adenylate cyclase-activating polypeptide (PACAP)/PAC1HOP1 receptor activation coordinates multiple neurotrophic signaling pathways: Akt activation through phosphatidylinositol 3-kinase gamma and vesicle endocytosis for neuronal survival. J. Biol. Chem. 285: 9749-9761.
    • (2010) J. Biol. Chem. , vol.285 , pp. 9749-9761
    • May, V.1
  • 15
    • 0026660275 scopus 로고
    • The 38-amino acid form of pituitary adenylate cyclase-activating polypeptide stimulates dual signaling cascades in PC12 cells and promotes neurite outgrowth
    • Deutsch, P.J. & Y. Sun 1992. The 38-amino acid form of pituitary adenylate cyclase-activating polypeptide stimulates dual signaling cascades in PC12 cells and promotes neurite outgrowth. J. Biol. Chem. 267: 5108-5113.
    • (1992) J. Biol. Chem. , vol.267 , pp. 5108-5113
    • Deutsch, P.J.1    Sun, Y.2
  • 16
    • 34047246691 scopus 로고    scopus 로고
    • The neuropeptide pituitary adenylate cyclase-activating polypeptide exerts anti-apoptotic and differentiating effects during neurogenesis: focus on cerebellar granule neurones and embryonic stem cells
    • Falluel-Morel, A. et al 2007. The neuropeptide pituitary adenylate cyclase-activating polypeptide exerts anti-apoptotic and differentiating effects during neurogenesis: focus on cerebellar granule neurones and embryonic stem cells. J. Neuroendocrinol. 19: 321-327.
    • (2007) J. Neuroendocrinol. , vol.19 , pp. 321-327
    • Falluel-Morel, A.1
  • 17
    • 27944499840 scopus 로고    scopus 로고
    • Endogenous PACAP acts as a stress response peptide to protect cerebellar neurons from ethanol or oxidative insult
    • Vaudry, D. et al 2005. Endogenous PACAP acts as a stress response peptide to protect cerebellar neurons from ethanol or oxidative insult. Peptides 26: 2518-2524.
    • (2005) Peptides , vol.26 , pp. 2518-2524
    • Vaudry, D.1
  • 18
    • 0030785348 scopus 로고    scopus 로고
    • Neuronal protection from apoptosis by pituitary adenylate cyclase-activating polypeptide
    • Tanaka, J. et al 1997. Neuronal protection from apoptosis by pituitary adenylate cyclase-activating polypeptide. Regul. Pept. 72: 1-8.
    • (1997) Regul. Pept. , vol.72 , pp. 1-8
    • Tanaka, J.1
  • 19
    • 0030481081 scopus 로고    scopus 로고
    • VIP and PACAP receptor-mediated actions on cell proliferation and survival
    • Waschek, J.A. 1996. VIP and PACAP receptor-mediated actions on cell proliferation and survival. Ann. N.Y. Acad. Sci. 805: 290-300.
    • (1996) Ann. N.Y. Acad. Sci. , vol.805 , pp. 290-300
    • Waschek, J.A.1
  • 20
    • 77953500031 scopus 로고    scopus 로고
    • Cardioprotective effect of endogenous pituitary adenylate cyclase-activating polypeptide on doxorubicin-induced cardiomyopathy in mice
    • Mori, H. et al 2010. Cardioprotective effect of endogenous pituitary adenylate cyclase-activating polypeptide on doxorubicin-induced cardiomyopathy in mice. Circ. J. 74: 1183-1190.
    • (2010) Circ. J. , vol.74 , pp. 1183-1190
    • Mori, H.1
  • 21
    • 0034994996 scopus 로고    scopus 로고
    • Pituitary adenylate cyclase activating polypeptide is highly abundant in the nervous system of anoxia-tolerant turtle, Pseudemys scripta elegans
    • Reglodi, D. et al 2001. Pituitary adenylate cyclase activating polypeptide is highly abundant in the nervous system of anoxia-tolerant turtle, Pseudemys scripta elegans. Peptides 22: 873-878.
    • (2001) Peptides , vol.22 , pp. 873-878
    • Reglodi, D.1
  • 23
    • 0030595848 scopus 로고    scopus 로고
    • PACAP in the adrenal gland-relationship with choline acetyltransferase, enkephalin and chromaffin cells and effects of immunological sympathectomy
    • Holgert, H. et al 1996. PACAP in the adrenal gland-relationship with choline acetyltransferase, enkephalin and chromaffin cells and effects of immunological sympathectomy. Neuroreport 20: 297-301.
    • (1996) Neuroreport , vol.20 , pp. 297-301
    • Holgert, H.1
  • 24
    • 0030570488 scopus 로고    scopus 로고
    • Expression of pituitary adenylate cyclase-activating peptide (PACAP) and PACAP type I receptors in the rat adrenal medulla
    • Moller, K. & F. Sundler 1996. Expression of pituitary adenylate cyclase-activating peptide (PACAP) and PACAP type I receptors in the rat adrenal medulla. Regul. Pept. 63: 129-139.
    • (1996) Regul. Pept. , vol.63 , pp. 129-139
    • Moller, K.1    Sundler, F.2
  • 25
    • 0037039471 scopus 로고    scopus 로고
    • Pituitary adenylate cyclase activating polypeptide is a sympathoadrenal neurotransmitter involved in catecholamine regulation and glucohomeostasis
    • Hamelink, C. et al 2002. Pituitary adenylate cyclase activating polypeptide is a sympathoadrenal neurotransmitter involved in catecholamine regulation and glucohomeostasis. Proc. Natl. Acad. Sci. U.S.A. 99: 461-466.
    • (2002) Proc. Natl. Acad. Sci. U.S.A. , vol.99 , pp. 461-466
    • Hamelink, C.1
  • 26
    • 73749083218 scopus 로고    scopus 로고
    • Stress hormone synthesis in mouse hypothalamus and adrenal gland triggered by restraint is dependent on pituitary adenylate cyclase-activating polypeptide signaling
    • Stroth, N. & L.E. Eiden 2010. Stress hormone synthesis in mouse hypothalamus and adrenal gland triggered by restraint is dependent on pituitary adenylate cyclase-activating polypeptide signaling. Neuroscience 165: 1025-1030.
    • (2010) Neuroscience , vol.165 , pp. 1025-1030
    • Stroth, N.1    Eiden, L.E.2
  • 27
    • 0029555233 scopus 로고
    • Sympathoadrenal system in stress. Interaction with the hypothalamic-pituitary-adrenocortical system
    • Kvetnansky, R. et al 1995. Sympathoadrenal system in stress. Interaction with the hypothalamic-pituitary-adrenocortical system. Ann. N.Y. Acad. Sci. 771: 131-158.
    • (1995) Ann. N.Y. Acad. Sci. , vol.771 , pp. 131-158
    • Kvetnansky, R.1
  • 28
    • 79151482833 scopus 로고    scopus 로고
    • Neuropeptides, growth factors and cytokines: a cohort of informational molecules whose expression is up-regulated by the stress-associated slow transmitter PACAP in chromaffin cells
    • Ait-Ali, D. et al 2010. Neuropeptides, growth factors and cytokines: a cohort of informational molecules whose expression is up-regulated by the stress-associated slow transmitter PACAP in chromaffin cells. Cell. Mol. Neurobiol. 30: 1441-1449.
    • (2010) Cell. Mol. Neurobiol , vol.30 , pp. 1441-1449
    • Ait-Ali, D.1
  • 29
    • 17344383389 scopus 로고    scopus 로고
    • High expression of stanniocalcin in differentiated brain neurons
    • Zhang, K.Z. et al 1998. High expression of stanniocalcin in differentiated brain neurons. Am. J. Pathol. 153: 439-445.
    • (1998) Am. J. Pathol. , vol.153 , pp. 439-445
    • Zhang, K.Z.1
  • 30
    • 0034724230 scopus 로고    scopus 로고
    • Stanniocalcin: a molecular guard of neurons during cerebral ischemia
    • Zhang, K. et al 2000. Stanniocalcin: a molecular guard of neurons during cerebral ischemia. Proc. Natl. Acad. Sci. U.S.A. 97: 3637-3642.
    • (2000) Proc. Natl. Acad. Sci. U.S.A. , vol.97 , pp. 3637-3642
    • Zhang, K.1
  • 31
    • 3242793276 scopus 로고    scopus 로고
    • Differentiated Paju cells have increased resistance to toxic effects of potassium ionophores
    • Teplova, V. et al 2004. Differentiated Paju cells have increased resistance to toxic effects of potassium ionophores. Acta. Biochim. Pol. 51: 539-544.
    • (2004) Acta. Biochim. Pol. , vol.51 , pp. 539-544
    • Teplova, V.1
  • 32
    • 34247557605 scopus 로고    scopus 로고
    • Stanniocalcin 1 prevents cytosolic Ca2+ overload and cell hypercontracture in cardiomyocytes
    • Koizumi, K. et al 2007. Stanniocalcin 1 prevents cytosolic Ca2+ overload and cell hypercontracture in cardiomyocytes. Circ. J. 71: 796-801.
    • (2007) Circ. J. , vol.71 , pp. 796-801
    • Koizumi, K.1
  • 33
    • 34548409609 scopus 로고    scopus 로고
    • Hypoxic preconditioning induces elevated expression of stanniocalcin-1 in the heart
    • Westberg, J.A. et al 2007. Hypoxic preconditioning induces elevated expression of stanniocalcin-1 in the heart. Am. J. Physiol. Heart Circ. Physiol. 293: H1766-H1771.
    • (2007) Am. J. Physiol. Heart Circ. Physiol. , vol.293
    • Westberg, J.A.1
  • 34
    • 33947497788 scopus 로고    scopus 로고
    • Hypoxic preconditioning induces neuroprotective stanniocalcin-1 in brain via IL-6 signaling
    • Westberg, J.A. et al 2007. Hypoxic preconditioning induces neuroprotective stanniocalcin-1 in brain via IL-6 signaling. Stroke 38: 1025-1030.
    • (2007) Stroke , vol.38 , pp. 1025-1030
    • Westberg, J.A.1
  • 35
    • 0036905708 scopus 로고    scopus 로고
    • Analysis of the PC12 cell transcriptome after differentiation with pituitary adenylate cyclase-activating polypeptide (PACAP)
    • Vaudry, D. et al 2002. Analysis of the PC12 cell transcriptome after differentiation with pituitary adenylate cyclase-activating polypeptide (PACAP). J. Neurochem. 83: 1272-1284.
    • (2002) J. Neurochem. , vol.83 , pp. 1272-1284
    • Vaudry, D.1
  • 36
    • 56649108177 scopus 로고    scopus 로고
    • Discovery of PACAP-related genes through microarray analyses in cell culture and in vivo
    • Eiden, L.E. et al 2008. Discovery of PACAP-related genes through microarray analyses in cell culture and in vivo. Ann. N.Y. Acad. Sci. 1144: 6-20.
    • (2008) Ann. N.Y. Acad. Sci. , vol.1144 , pp. 6-20
    • Eiden, L.E.1
  • 37
    • 44249121484 scopus 로고    scopus 로고
    • A cAMP-dependent, PKA-independent signaling pathway mediating neuritogenesis through Egr1 in PC12 cells
    • Ravni, A. et al 2008. A cAMP-dependent, PKA-independent signaling pathway mediating neuritogenesis through Egr1 in PC12 cells. Mol. Pharmacol. 73: 1688-1708.
    • (2008) Mol. Pharmacol. , vol.73 , pp. 1688-1708
    • Ravni, A.1
  • 38
    • 0036662774 scopus 로고    scopus 로고
    • Coincident elevation of cyclic AMP and calcium influx by PACAP-27 synergistically regulates VIP gene transcription through a novel PKA-independent signaling pathway
    • Hamelink, C. et al 2002. Coincident elevation of cyclic AMP and calcium influx by PACAP-27 synergistically regulates VIP gene transcription through a novel PKA-independent signaling pathway. J. Neurosci. 22: 5310-5320.
    • (2002) J. Neurosci. , vol.22 , pp. 5310-5320
    • Hamelink, C.1
  • 39
    • 0032995872 scopus 로고    scopus 로고
    • Sp1/Egr1 motif: a new candidate in the regulation of rat tyrosine hydroxylase gene transcription by immobilization stress
    • Papanikolaou, N.A. & E.L. Sabban 1999. Sp1/Egr1 motif: a new candidate in the regulation of rat tyrosine hydroxylase gene transcription by immobilization stress. J. Neurochem. 73: 433-436.
    • (1999) J. Neurochem. , vol.73 , pp. 433-436
    • Papanikolaou, N.A.1    Sabban, E.L.2
  • 40
    • 36348953165 scopus 로고    scopus 로고
    • Pituitary adenylate cyclase-activating polypeptide stimulates corticotropin-releasing factor, vasopressin and interleukin-6 gene transcription in hypothalamic 4B cells
    • Kageyama, K. et al 2007. Pituitary adenylate cyclase-activating polypeptide stimulates corticotropin-releasing factor, vasopressin and interleukin-6 gene transcription in hypothalamic 4B cells. J. Endocrinol. 195: 199-211.
    • (2007) J. Endocrinol. , vol.195 , pp. 199-211
    • Kageyama, K.1
  • 41
    • 0035818539 scopus 로고    scopus 로고
    • Altered psychomotor behaviors in mice lacking pituitary adenylate cyclase-activating polypeptide (PACAP)
    • Hashimoto, H. et al 2001. Altered psychomotor behaviors in mice lacking pituitary adenylate cyclase-activating polypeptide (PACAP). Proc. Natl. Acad. Sci. U.S.A. 98: 13355-13360.
    • (2001) Proc. Natl. Acad. Sci. U.S.A. , vol.98 , pp. 13355-13360
    • Hashimoto, H.1
  • 42
    • 0035882445 scopus 로고    scopus 로고
    • Altered emotional behavior in PACAP-type-I-receptor-deficient mice
    • Otto, C. et al 2001. Altered emotional behavior in PACAP-type-I-receptor-deficient mice. Brain Res. Mol. Brain Res. 92: 78-84.
    • (2001) Brain Res. Mol. Brain Res. , vol.92 , pp. 78-84
    • Otto, C.1
  • 44
    • 33750969341 scopus 로고    scopus 로고
    • Neuroprotection by endogenous and exogenous PACAP following stroke
    • Chen, Y. et al 2006. Neuroprotection by endogenous and exogenous PACAP following stroke. Regul. Pept. 137: 4-19.
    • (2006) Regul. Pept. , vol.137 , pp. 4-19
    • Chen, Y.1
  • 45
    • 0036948319 scopus 로고    scopus 로고
    • Effects of pretreatment with PACAP on the infarct size and functional outcome in rat permanent focal cerebral ischemia
    • Reglodi, D. et al 2002. Effects of pretreatment with PACAP on the infarct size and functional outcome in rat permanent focal cerebral ischemia. Peptides 23: 2227-2234.
    • (2002) Peptides , vol.23 , pp. 2227-2234
    • Reglodi, D.1
  • 46
    • 33646596542 scopus 로고    scopus 로고
    • Pituitary adenylate cyclase-activating polypeptide (PACAP) decreases ischemic neuronal cell death in association with IL-6
    • Ohtaki, H. et al 2006. Pituitary adenylate cyclase-activating polypeptide (PACAP) decreases ischemic neuronal cell death in association with IL-6. Proc. Natl. Acad. Sci. U.S.A. 103: 7488-7493.
    • (2006) Proc. Natl. Acad. Sci. U.S.A. , vol.103 , pp. 7488-7493
    • Ohtaki, H.1
  • 47
    • 79151472642 scopus 로고    scopus 로고
    • Adrenal responses to stress
    • Goldstein, D.S. 2010. Adrenal responses to stress. Cell Mol. Neurobiol. 30: 1433-1440.
    • (2010) Cell Mol. Neurobiol. , vol.30 , pp. 1433-1440
    • Goldstein, D.S.1
  • 48
    • 67649995436 scopus 로고    scopus 로고
    • Catecholaminergic systems in stress: structural and molecular genetic approaches
    • Kvetnansky, R., E.L. Sabban & M. Palkovits 2009. Catecholaminergic systems in stress: structural and molecular genetic approaches. Physiol. Rev. 89: 535-606.
    • (2009) Physiol. Rev. , vol.89 , pp. 535-606
    • Kvetnansky, R.1    Sabban, E.L.2    Palkovits, M.3
  • 49
    • 3242673267 scopus 로고    scopus 로고
    • Molecular regulation of gene expression of catecholamine biosynthetic enzymes by stress: sympathetic ganglia versus adrenal medulla
    • Sabban, E.L. et al 2004. Molecular regulation of gene expression of catecholamine biosynthetic enzymes by stress: sympathetic ganglia versus adrenal medulla. Ann. N.Y. Acad. Sci. 1018: 370-377.
    • (2004) Ann. N.Y. Acad. Sci. , vol.1018 , pp. 370-377
    • Sabban, E.L.1
  • 50
    • 57649213510 scopus 로고    scopus 로고
    • Identifying the stress transcriptome in the adrenal medulla following acute and repeated immobilization
    • Liu, X. et al 2008. Identifying the stress transcriptome in the adrenal medulla following acute and repeated immobilization. Ann. N.Y. Acad. Sci. 1148: 1-28.
    • (2008) Ann. N.Y. Acad. Sci. , vol.1148 , pp. 1-28
    • Liu, X.1
  • 51
    • 0034255507 scopus 로고    scopus 로고
    • Fos-related antigen 2: potential mediator of the transcriptional activation in rat adrenal medulla evoked by repeated immobilization stress
    • Nankova, B.B. et al 2000. Fos-related antigen 2: potential mediator of the transcriptional activation in rat adrenal medulla evoked by repeated immobilization stress. J. Neurosci. 20: 5647-5653.
    • (2000) J. Neurosci. , vol.20 , pp. 5647-5653
    • Nankova, B.B.1
  • 52
    • 0032856518 scopus 로고    scopus 로고
    • Multiple signalling pathways exist in the stress-triggered regulation of gene expression for catecholamine biosynthetic enzymes and several neuropeptides in the rat adrenal medulla
    • Nankova, B.B. & E.L. Sabban 1999. Multiple signalling pathways exist in the stress-triggered regulation of gene expression for catecholamine biosynthetic enzymes and several neuropeptides in the rat adrenal medulla. Acta Physiol. Scand. 167: 1-9.
    • (1999) Acta Physiol. Scand. , vol.167 , pp. 1-9
    • Nankova, B.B.1    Sabban, E.L.2
  • 53
    • 0034282856 scopus 로고    scopus 로고
    • Ability of Egr1 to activate tyrosine hydroxylase transcription in PC12 cells
    • Papanikolaou, N.A. & E.L. Sabban 2000. Ability of Egr1 to activate tyrosine hydroxylase transcription in PC12 cells. J. Biol. Chem. 275: 26683-26689.
    • (2000) J. Biol. Chem. , vol.275 , pp. 26683-26689
    • Papanikolaou, N.A.1    Sabban, E.L.2
  • 54
    • 0032502579 scopus 로고    scopus 로고
    • Pituitary adenylate cyclase-activating polypeptide-nerve terminals densely innervate corticotropin-releasing hormone-neurons in the hypothalamic paraventricular nucleus of the rat
    • Legradi, G., J. Hannibal & R.M. Lechan 1998. Pituitary adenylate cyclase-activating polypeptide-nerve terminals densely innervate corticotropin-releasing hormone-neurons in the hypothalamic paraventricular nucleus of the rat. Neurosci. Lett. 246: 145-148.
    • (1998) Neurosci. Lett. , vol.246 , pp. 145-148
    • Legradi, G.1    Hannibal, J.2    Lechan, R.M.3
  • 55
    • 22744433147 scopus 로고    scopus 로고
    • Pituitary adenylate cyclase-activating polypeptide (PACAP) mimics neuroendocrine and behavioral manifestations of stress: evidence for PKA-mediated expression of the corticotropin-releasing hormone (CRH) gene
    • Agarwal, A., L.M. Halvorson & G. Legradi 2005. Pituitary adenylate cyclase-activating polypeptide (PACAP) mimics neuroendocrine and behavioral manifestations of stress: evidence for PKA-mediated expression of the corticotropin-releasing hormone (CRH) gene. Brain Res. Mol. Brain Res. 138: 45-57.
    • (2005) Brain Res. Mol. Brain Res. , vol.138 , pp. 45-57
    • Agarwal, A.1    Halvorson, L.M.2    Legradi, G.3
  • 56
    • 0030726726 scopus 로고    scopus 로고
    • Effects of pituitary adenylate cyclase-activating polypeptide (PACAP) on corticotropin-releasing hormone (CRH) gene expression in the rat hypothalamic paraventricular nucleus
    • Grinevich, V., A. Fournier & G. Pelletier 1997. Effects of pituitary adenylate cyclase-activating polypeptide (PACAP) on corticotropin-releasing hormone (CRH) gene expression in the rat hypothalamic paraventricular nucleus. Brain Res. 773: 190-196.
    • (1997) Brain Res. , vol.773 , pp. 190-196
    • Grinevich, V.1    Fournier, A.2    Pelletier, G.3
  • 57
    • 0037175342 scopus 로고    scopus 로고
    • Pituitary adenylate cyclase-activating peptide in the rat central nervous system: an immunohistochemical and in situ hybridization study
    • Hannibal, J. 2002. Pituitary adenylate cyclase-activating peptide in the rat central nervous system: an immunohistochemical and in situ hybridization study. J. Comp. Neurol. 453: 389-417.
    • (2002) J. Comp. Neurol. , vol.453 , pp. 389-417
    • Hannibal, J.1
  • 58
    • 0005739565 scopus 로고    scopus 로고
    • PACAP gene expression in neurons of the rat hypothalamo-pituitary-adrenocortical axis is induced by endotoxin and interleukin-1beta
    • Hannibal, J. et al 1999. PACAP gene expression in neurons of the rat hypothalamo-pituitary-adrenocortical axis is induced by endotoxin and interleukin-1beta. Neuroendocrinology 70: 73-82.
    • (1999) Neuroendocrinology , vol.70 , pp. 73-82
    • Hannibal, J.1
  • 59
    • 0037111489 scopus 로고    scopus 로고
    • Regulation of neurotrophic peptide expression in sympathetic neurons: quantitative analysis using radioimmunoassay and real-time quantitative polymerase chain reaction
    • Girard, B.M. et al 2002. Regulation of neurotrophic peptide expression in sympathetic neurons: quantitative analysis using radioimmunoassay and real-time quantitative polymerase chain reaction. Regul. Pept. 109: 89-101.
    • (2002) Regul. Pept. , vol.109 , pp. 89-101
    • Girard, B.M.1
  • 60
    • 0033638849 scopus 로고    scopus 로고
    • The sympathetic nerve-an integrative interface between two supersystems: the brain and the immune system
    • Elenkov, I. J. et al 2000. The sympathetic nerve-an integrative interface between two supersystems: the brain and the immune system. Pharmacol. Rev. 52: 595-638.
    • (2000) Pharmacol. Rev. , vol.52 , pp. 595-638
    • Elenkov, I.J.1
  • 61
    • 77956730171 scopus 로고    scopus 로고
    • Stressor specificity of peripheral catecholaminergic activation
    • Kvetnansky, R. et al 1998. Stressor specificity of peripheral catecholaminergic activation. Adv. Pharmacol. 42: 556-560.
    • (1998) Adv. Pharmacol. , vol.42 , pp. 556-560
    • Kvetnansky, R.1
  • 62
    • 67349180729 scopus 로고    scopus 로고
    • Chronic stress increases pituitary adenylate cyclase-activating peptide (PACAP) and brain-derived neurotrophic factor (BDNF) mRNA expression in the bed nucleus of the stria terminalis (BNST): roles for PACAP in anxiety-like behavior
    • Hammack, S.E. et al 2009. Chronic stress increases pituitary adenylate cyclase-activating peptide (PACAP) and brain-derived neurotrophic factor (BDNF) mRNA expression in the bed nucleus of the stria terminalis (BNST): roles for PACAP in anxiety-like behavior. Psychoneuroendocrinology 34: 833-843.
    • (2009) Psychoneuroendocrinology , vol.34 , pp. 833-843
    • Hammack, S.E.1
  • 63
    • 78349308989 scopus 로고    scopus 로고
    • Roles for pituitary adenylate cyclase-activating peptide (PACAP) expression and signaling in the bed nucleus of the stria terminals (BNST) in mediating the behavioral consequences of chronic stress
    • Hammack, S.E. et al 2010. Roles for pituitary adenylate cyclase-activating peptide (PACAP) expression and signaling in the bed nucleus of the stria terminals (BNST) in mediating the behavioral consequences of chronic stress. J. Mol. Neurosci. 42: 327-340.
    • (2010) J. Mol. Neurosci. , vol.42 , pp. 327-340
    • Hammack, S.E.1
  • 64
    • 0033997773 scopus 로고    scopus 로고
    • Circuits and mechanisms governing hypothalamic responses to stress: a tale of two paradigms
    • Sawchenko, P.E., H.Y. Li & A. Ericsson 2000. Circuits and mechanisms governing hypothalamic responses to stress: a tale of two paradigms. Prog. Brain Res. 122: 61-78.
    • (2000) Prog. Brain Res. , vol.122 , pp. 61-78
    • Sawchenko, P.E.1    Li, H.Y.2    Ericsson, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.