Targeting chemokine receptors in disease - A case study of CCR4

European Journal of Pharmacology

Volumn 763, Issue , 2015, Pages 169-177

  Solari, Roberto ^a   Pease, James E ^b  

^a NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Antagonist; Asthma leukaemia; Chemokine; Inflammation; Receptor; Signaling

Indexed keywords

BMS 397; CHEMOKINE RECEPTOR CCR4; CHEMOKINE RECEPTOR CCR4 ANTAGONIST; GSK 2239633; K 777; MACROPHAGE DERIVED CHEMOKINE; MOGALIZUMAB; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY KM 2160; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; PLECKSTRIN; RETINA S ANTIGEN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; SCAFFOLD PROTEIN; THYMUS AND ACTIVATION REGULATED CHEMOKINE; UNCLASSIFIED DRUG;

ALLERGIC ASTHMA; ARTICLE; CARBOXY TERMINAL SEQUENCE; CYTOKINE PRODUCTION; DRUG EFFICACY; DRUG MECHANISM; DRUG STRUCTURE; DRUG TARGETING; HUMAN; INTRACELLULAR SIGNALING; LIGAND BINDING; MOLECULAR PATHOLOGY; NONHUMAN; OUTCOME ASSESSMENT; PHASE 2 CLINICAL TRIAL (TOPIC); PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LIPID INTERACTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; RECEPTOR BINDING; SKIN ALLERGY; STRUCTURE ACTIVITY RELATION; T CELL LYMPHOMA; UPREGULATION; ANIMAL; ANTAGONISTS AND INHIBITORS; DISEASES; METABOLISM; MOLECULARLY TARGETED THERAPY; PROCEDURES;

ANIMALS; DISEASE; HUMANS; MOLECULAR TARGETED THERAPY; RECEPTORS, CCR4;

EID: 84942363815     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2015.05.018     Document Type: Article

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