Significantly elevated expression of PF4 (platelet factor 4) and eotaxin in the NOA mouse, a model for atopic dermatitis

Journal of Human Genetics

Volumn 44, Issue 3, 1999, Pages 173-176

  Watanabe, Otsu ^a   Natori, Kyoko ^a   Tamari, Mayumi ^a   Shiomoto, Yasuhisa ^b   Kubo, Shuji ^b   Nakamura, Yusuke ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b OTSUKA PHARMACEUTICAL CO LTD   (Japan)

Author keywords

Atopic dermatitis; Chemokine; Differential display method; Model mouse; MRNA expression

Indexed keywords

BETA ACTIN; CHEMOKINE; DNA; EOTAXIN; HEPARIN BINDING PROTEIN; IMMUNOGLOBULIN E; MESSENGER RNA; RANTES; THROMBOCYTE FACTOR 4;

AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATOPIC DERMATITIS; CONTROLLED STUDY; DNA SEQUENCE; EOSINOPHIL; MAST CELL; MOLECULAR CLONING; MOUSE; NONHUMAN; NORTHERN BLOTTING; OPEN READING FRAME; PROTEIN EXPRESSION; SKIN ALLERGY; SPLEEN;

AMINO ACID SEQUENCE; ANIMALS; CHEMOKINES, CC; CYTOKINES; DERMATITIS, ATOPIC; DISEASE MODELS, ANIMAL; DNA, COMPLEMENTARY; GENE AMPLIFICATION; GENE EXPRESSION; MICE; MICE, INBRED C57BL; MOLECULAR SEQUENCE DATA; PLATELET FACTOR 4; RNA, MESSENGER; SEQUENCE HOMOLOGY, AMINO ACID; SPLEEN;

EID: 0032944476     PISSN: 14345161     EISSN: None     Source Type: Journal    
DOI: 10.1007/s100380050136     Document Type: Article

References (23)

1. Alam R, Stafford S, Forsythe P, Harrison R, Faubion D, Lett- Brown MA, Grant JA (1993) RANTES is a chemotactic and activating factor for human eosinophils. J Immunol 150: 3442-3448
2. Broekman MJ, Handin RI, Cohen P (1975) Distribution of fibrinogen and platelet factor 4 and XIII in subcellular fractions of human platelets. Br J Haematol 31: 51-55
3. Bruijinzeel Pl, Kuijiper PH, Rihs S, Betz S, Warringa RA, Koenderman L (1993) Eosinophil migration in atopic dermatitis. Increased migratory response to N-formyl-methionyl-leusil-phenylalanine, neutrophil-activating factor, platelet-activating factor, and platelet factor 4. J Invest Dermatol 100: 137-142
4. Coleman R, Trembath RC, Harper JI (1997). Genetic studies of atopy and atopic dermatitis. Br J Dermatol 136: 1-5
5. Cookson WO, Young RP, Sandford AJ, Moffatt MF, Shirakawa T, Sharp PA, Faux JA, Julier C, Nakumuura Y (1992) Maternal inheritance of atopic IgE responsiveness on chromosome 11q. Lancet 15: 381-384
6. Doi T, Greenberg SM, Rosenberg RD (1987) Structure of the rat platelet factor 4 gene: a marker for megakaryocyte differentiation. Mol Cell Biol 7: 898-904
7. Garcia-Zepeda EA, Rothenberg ME, Ownbey RT, Celestin J, Leder P, Luster AD (1996) Human eotaxin is a specific chemoattractant for eosinophil cells and provides a new mechanism to explain tissue eosinophilia. Nat Med 2: 449-456
8. Hanifin JM, Rajka G (1980) Diagnostic features of atopic dermatitis. Acta Dermao-Venereol Suppl 92: 44-47
9. Hizawa N, Yamaguchi E, Ohe M, Itoh A, Furuya K, Ohnuma N, Kawakami, Y (1992) Lack of linkage between atopy and locus 11q13. Clin Exp Allergy/ 22: 1065-1069
10. Kaplan Kl, Broekman MJ, Chernoff A, lesznik GR, and Drillings M (1979) Platelet α-granule proteins. Studies on release and subcellular localization. Blood 53: 604-618
11. Kofler H, Aichberger S, Ott G, Casari A, Kofler R (1996) Lack of association between atopy and the I1e181Leu variant of the beta-subunit of the high-affinity immunoglobulin E receptor. Int Arch Allergy Immunol 111: 44-47
12. Kondo T, Shiomoto Y, Kondo T, Kubo S (1997) The NOA mouse, a new hair-deficient mutant (A possible animal model of allergic dermatitis). Mouse Genome 95: 698-700
13. Liang P, Pardee AB (1992) Differential display of eukaryotic messenger RNA by means of the polymerase chain reaction. Science 257: 967-971
14. Lim J, Kuroki T, Ozaki K, Kohsaki H, Yamori T, Tsuruo T, Nakamori S, Imaoka S, Endo M, Nakamura Y (1997) Isolation of murine and human homologues of the Fission-Yeast dis+ gene encoding a mitotic-control protein and its overexpression in cancer cells with progressive phenotype. Cancer Res 57: 921-925
15. Marsh DG, Neely JD, Breazeale DR, Ghosh B, Freidhoff LR, Ehrlich-Kantzky E, Schon C, Krishnaswamy G, Beaty TH (1994) Linkage analysis of IL4 and other chromosome 5q31.1 markers and total serum immunoglobulin E concentrations. Science 264: 1152-1156
16. Moore S, Pepper DS, Cash JD (1975) Platelet antiheparin activity: The isolation and characterization of platelet factor 4 released from thrombin-aggregated washed human platelets and its disassociation into subunits and the isolation of membrane-bound antiheparin activity. Biochem Biophys Acta 379: 370-384
17. Noguchi E, Shibasaki M, Arinami T, Takeda K. Maki T, Miyamoto T, Kawashima T, Kobayashi K, Hamaguchi H (1997) Evidence for linkage between asthma/atopy in childhood and chromosome 5q31-5q33 in a Japanese population. Am J Respir Crit Care Med 156: 1390-1393
18. Ozaki K, Kuroki T, Hayashi S, Nakamura Y (1996) Isolation of three testis-specific genes (TSA303, TSA806, TSA903) by a differential mRNA method. Genomics 36: 316-319
19. Poncz M, Surrey S, LaRocco P, Weiss MJ, Rappaport EF, Conway TM, Schwartz E (1987) Cloning and characterization of platelet factor 4 cDNA derived from a human erythroleukemic cell line. Blood 69: 219-223
20. Rucinski B, Niewiarowski S, James P, Walz DA, Budzynski AZ (1979) Anti-heparin proteins secreted by human platelets: Purification and characterization and radioimmunoassay. Blood 53: 47-62
21. Ryo R, Nakeff A, Huang SS, Ginsberg M, Deuel TF (1983) New synthesis of a platelet-specific protein: Platelet factor 4 synthesis in a megakaryocyte-rabbit bone marrow culture system. J Cell Biol 96: 515-520
22. Shirakawa T, Li A, Dubowitz M. Dekker JW, Shaw AE, Faux JA, Ra C, Cookson WO, Hopkin JM (1994) Association between atopy and variants of the β subunit of the high-affinity immunoglobulin E receptor. Nat Genet 7: 125-130
23. Yamada H, Izutani R, Chihara J, Yudate T, Mtsukura M, Tezuka T (1996) RANTES mRNA expression in skin and colon of patients with atopic dermatitis. Int Arch Allerg Immunol 111: 19-21