The chemokine receptor CCR4 in vascular recognition by cutaneous but not intestinal memory T cells

Nature

Volumn 400, Issue 6746, 1999, Pages 776-780

  Campbell, J J ^a,b   Haraldsen, G ^a,b,d   Pan, J ^a,b   Rottman, J ^c   Qin, S ^c   Ponath, P ^c   Andrew, D P ^c   Warnke, R ^a   Ruffing, N ^c   Kassam, N ^c   Wu, L ^c   Butcher, E C ^a,b  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Ctr for Molec Biology and Medicine   (United States)

^c MILLENNIUM PHARMACEUTICALS INC   (United States)

^d UNIVERSITY OF OSLO   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CXCR4; INTERCELLULAR ADHESION MOLECULE 1;

ARTICLE; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; INTESTINE LYMPHATIC TISSUE; LAMINA PROPRIA; LYMPHOCYTIC INFILTRATION; MEMORY CELL; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DETERMINATION; SKIN INFLAMMATION;

CHEMOKINES, CC; CHEMOTAXIS, LEUKOCYTE; HUMANS; IMMUNOLOGIC MEMORY; INFLAMMATION; INTESTINES; RECEPTORS, CHEMOKINE; SKIN; T-LYMPHOCYTES; VENULES;

EID: 0033584358     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/23495     Document Type: Article

References (30)

1. Butcher, E. C., Williams, M., Youngman, K., Rott, L. & Briskin, M. Lymphocyte trafficking and regional immunity. Adv. Immunol. 72, 209-253 (1999).
2. Zlotnik, A., Morales, J. & Hedrick, J A. Recent advances in chernokines and chemokine receptor. Crit. Rev. Immunol. 19, 1-47 (1999).
3. Butcher, E. C. Leukocyte-endothelial cell recognition: three (or more) steps to specificity and diversity. Cell 67, 1033-1036 (1991).
4. Campbell, J J. et al. Chemokines and the arrest of lymphocytes rolling under flow conditions. Science 279, 381-384 (1998).
5. Gunn, M. D. et al. A chemokine expressed in lymphoid high endothelial venules promotes the adhesion and chemotaxis of naive T lymphocytes. Proc. Natl Acad. Sci. USA 95, 258-263 (1998).
6. Power, C. A. et al. Molecular cloning and functional expression of a novel CC chemokine receptor cDNA from a human basophilic cell line. J. Biol. Chem. 270, 19495-19500 (1995).
7. Campbell, J. J., Qin, S., Bacon, K. B., Mackay, C. R. & Butcher, E. C. Biology of chemokine and classical chemoattractant receptors: differential requirements for adhesion-triggering versus chemotactic responses in lymphoid cells. J. Cell Biol. 134, 255-266 (1996).
8. Campbell, J. J. et al. 6-C-kine (SLC), a lymphocyte adhesion-triggering chemokine expressed by high endothelium, is an agonist for the MIP-3β receptor CCR7. J. Cell Biol. 141, 1053-1059 (1998).
9. Mackay, C. R., Andrew, D. P., Briskin, M., Ringler, D. J. & Butcher, E. C. Phenotype and migration properties of three major subsets of tissue homing T cells in sheep. Eur. J. Immunol. 26, 2433-2439 (1996).
10. Williams, M. B. & butcher, E. C. Homing of naive and memory T lymphocyte subsets to Peyer's patches, lymph nodes, and spleen. J. Immunol. 159, 1746-1752 (1997).
11. Santamaria Babi, L. F. et al. Circulating allergen-reactive T cells from patients with atopic dermatitis and allergic contact dermatitis express the skin-selective homing receptor, the cutaneous lymphocyte-associated antigen. J. Exp. Med. 181, 1935-1940 (1995).
12. Picker, L. J., Michie, S. A., Rott, L. S. & Butcher, E. C. A unique phenotype of skin-associated lymphocytes in humans. Preferential expression of the HECA-452 epitope by benign and malignant T cells at cutaneous sites. Am. J. Pathol. 136, 1053-1068 (1990).
13. Berg, E. L. et al. The cutaneous lymphocyte antigen is a skin lymphocyte homing receptor for the vascular lectin endothelial cell-leukocyte adhesion molecule 1. J. Exp. Med. 174, 1461-1466 (1991).
14. Anderson, A. O. & Shaw, S. T-cell adhesion to endothelium: the FRC conduit system and other anatomic and molecular features which facilitate the adhesion cascade in lymph node. Semin. Immunol. 5, 271-282 (1993).
15. Middleton, J. et al. Transcytosis and surface presentation of IL-8 by venular endothelial cells. Cell 91, 385-395 (1997).
16. Utgaard, J. O., Jahnsen, F. L., Bakka, A., Brandtzaeg, P. & Haraldsen, G. Rapid secretion of prestored interleukin 8 from Weibel-Palade bodies of microvascular endothelial cells. J. Exp. Med. 188, 1751-1756 (1998).
17. Baekkevold, E. S. et al. Culture characterization of differentiated high endothelial venule cells from human tonsils. Lab. Invest. 79, 327-336 (1999).
18. Silber, A. et al. Recruitment of lymphocytes during cutaneous delayed hypersensitivity in nonhuman primates is dependent on E-selectin and vascular cell adhesion molecule 1. J. Clin. Invest. 93, 1554-1563 (1994).
19. Balashov, K. E., Rottman, J. B., Weiner, H. L. & Hancock, W. W. CCR5(+) and CXCR3(+) T cells are increased in multiple sclerosis and their ligands MIP-1α and IP-10 are expressed in demyelinating brain lesions. Proc. Natl Acad. Sci. USA 96, 6873-6878 (1999).
20. Picker, L. J., Kishimoto, T. K., Smith, C. W., Warnock, R. A. & Butcher, E. C. ELAM-1 is an adhesion molecule for skin-homing T cells. Nature 349, 796-799 (1991).
21. Imai, T., Baba, M., Nishimua, M., Takagi, S. & Yoshie, O. The T cell-directed CC chemokine TARC is a highly specific biological ligand for CC chemokine receptor 4. J. Biol. Chem. 272, 15036-15042 (1997).
22. Bonecchi, R. et al. Differential expression of chemokine receptors and chemotactic responsiveness of type 1 T helper cells (Th1s) and Th2s. J. Exp. Med. 187, 129-134 (1998).
23. Andrew, D. P. et al. STCP-1 (MDC) CC chemokine acts specifically on chronically activated Th2 lymphocytes and is produced by monocytes on stimulation with Th2 cytokines IL-4 and IL-13. J. Immunol. 161, 5027-5038 (1998).
24. Sallusto, F., Lenig, D., Mackay, C. R. & Lanzavecchia, A. Flexible programs of chemokine receptor expression on human polarized T helper 1 and 2 lymphocytes. J. Exp. Med. 187, 875-883 (1998).
25. Austrup, F. et al. P- and E-selectin mediate recruitment of T-helper-1 but not T-helper-2 cells into inflammed tissues. Nature 385, 81-83 (1997).
26. Sallusto, F., Lanzavecchia, A. & Mackay, C. R. Chemokines and chemokine receptors in T-cell priming and Th1/Th2-mediated responses. Immunol. Today 19, 568-574 (1998).
27. D'Ambrosio, D. et al. Selective up-regulation of chemokine receptors CCR4 and CCR8 upon activation of polarized human type 2 Th cells. J. Immunol. 161, 5111-5115 (1998).
28. + memory T cell differentiation. J. Immunol. 159, 6018-6029 (1997).
29. Qin, S. et al. the chemokine receptors CXCR3 and CCR5 mark subsets of T cells associated with certain inflammatory reactions. J. Clin. Invest. 101, 746-754 (1998).
30. Qin, S. et al. Expression of monocyte chemoattractant protein-1 and interleukin-8 receptors on subsets of T cells: correlation with transendothelial chemotactic potential. Eur. J. Immunol. 26, 640-647 (1996).