Synthesis and structure-activity relationships of indazole arylsulfonamides as allosteric CC-chemokine receptor 4 (CCR4) antagonists

Journal of Medicinal Chemistry

Volumn 56, Issue 5, 2013, Pages 1946-1960

  Procopiou, Panayiotis A ^a   Barrett, John W ^a   Barton, Nicholas P ^a   Begg, Malcolm ^a   Clapham, David ^a   Copley, Royston C B ^a   Ford, Alison J ^a   Graves, Rebecca H ^a   Hall, David A ^a   Hancock, Ashley P ^a   Hill, Alan P ^a   Hobbs, Heather ^a   Hodgson, Simon T ^a   Jumeaux, Coline ^a   Lacroix, Yannick M L ^a   Miah, Afjal H ^a   Morriss, Karen M L ^a   Needham, Deborah ^a   Sheriff, Emma B ^a   Slack, Robert J ^a   Smith, Claire E ^a   Sollis, Steven L ^a   Staton, Hugo ^a   more..

^a GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CCR4; CHEMOKINE RECEPTOR CCR4 ANTAGONIST; INDAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ALLOSTERISM; ARTICLE; DRUG ACTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; NONHUMAN; PLASMA PROTEIN BINDING; X RAY DIFFRACTION;

ANIMALS; DOGS; HUMANS; INDAZOLES; MALE; RATS; RECEPTORS, CCR4; STRUCTURE-ACTIVITY RELATIONSHIP; SULFONAMIDES;

EID: 84875154676     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm301572h     Document Type: Article

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