STCP-1 (MDC) CC chemokine acts specifically on chronically activated Th2 lymphocytes and is produced by monocytes on stimulation with Th2 cytokines IL-4 and IL-13

Journal of Immunology

Volumn 161, Issue 9, 1998, Pages 5027-5038

  Andrew, David P ^a,b   Chang, Ming Shi ^a   McNinch, Jennifer ^a   Wathen, Scott T ^a   Rihanek, Marynette ^a   Tseng, Julia ^a   Spellberg, Jason P ^a   Chester III, G Elias ^a  

^a AMGEN INC   (United States)

^b MILLENNIUM PHARMACEUTICALS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOATTRACTANT; CHEMOKINE; CYTOKINE; EOTAXIN; INTERLEUKIN 4;

ARTICLE; CALCIUM TRANSPORT; CELL DIFFERENTIATION; CELL MIGRATION; DESENSITIZATION; DISULFIDE BOND; EFFECTOR CELL; HUMAN; HUMAN CELL; LYMPHOCYTE ACTIVATION; LYMPHOCYTE SUBPOPULATION; MEMORY CELL; MONOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION;

ANIMALS; B-LYMPHOCYTES; CALCIUM SIGNALING; CHEMOKINES; CHEMOKINES, CC; CHEMOKINES, CXC; CHEMOTAXIS, LEUKOCYTE; CYTOKINES; DENDRITIC CELLS; FEEDBACK; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HUMANS; IMMUNOLOGIC MEMORY; INTERLEUKIN-10; INTERLEUKIN-13; INTERLEUKIN-4; KILLER CELLS, NATURAL; LYMPHOCYTE ACTIVATION; MACROPHAGES; MICE; MICE, INBRED BALB C; MONOCYTES; RANTES; RECEPTORS, CHEMOKINE;

EID: 0032212311     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (43)

1. Taub, D. D., and J. J. Oppenheim. 1994. Chemokines, inflammation and the immune system. Ther. Immunol. 1:229.
2. Keiner, G. S., J. Kennedy, K. B. Bacon, S. Kleyensteuber, D. A. Largaespada, N. A. Jenkins, N. G. Copeland, J. F. Bazan, K. W. Moore, T. J. Schall, and A. Zlotnik. 1994. Lymphotactin: a cytokine that represents a new class of chemokine. Science 266:12395.
3. Bazan, J. F., K. B. Bacon, G. Hardoman, W. Wang, K. Soo, D. Rossi, D. R. Greaves, A. Zlotnik, and T. J. Schall. 1997. A new class of membrane bound chemokine with a CXxC motif. Nature 385:640.
4. Pin, Y., C. Lloyd, H. Zhou, S. Dollich, J. Deeds, J. Gonzalo, J. Vath, M. Gosselin, J. Ma, D. Dussault, E. Woolf, G. Alperin, J. Culpepper, J. C. Gutierrez, and D. Gearing. 1997. Neurotactin, a membrane anchored chemokine up-regulated in brain inflammation. Nature 385:611.
5. Mackay, C. R. 1996. Chemokine receptors and T cell chemotaxis. J. Exp. Med. 184:799.
6. Taub, D. D., M. Anver, J. J. Oppenheim, D. L. Longo, and W. J. Murphy. 1996. T lymphocyte recruitment by interleukin-8 (IL-8). J. Clin. Invest. 97:1931.
7. Fuentes, M. E., S. K. Durham, M. R. Swerdel, A. C. Lewin, D. S. Barton, J. R. Megil, R. Bravo, and S. A. Lira. 1995. Controlled recruitment of monocytes and macrophages to specific organs through transgenic expression of monocyte chemoattractant protein-1. J. Immunol. 155:5769.
8. Bargatze, R. F., and E. C. Butcher. 1993. G-protein regulated activation event involved in lymphocyte binding to high endothelial venules. J. Exp. Med. 178:367.
9. Sekido, N., N. Mukaida, A. Harada, I. Nakanishi, Y. Watanabe, and K. Matsushima. 1993. Prevention of lung reperfusion injury in rabbits by a monoclonal antibody against interleukin-8. Nature 365:654.
10. Karpus, W. J., N. W. Lukacs, B. L. McRae, R. M. Strieter, S. L. Kunkel, and S. D. Miller. 1995. An important role for the chemokine macrophage inflammatory protein-1α in the pathogenesis of the T cell-mediated autoimmune disease, experimental autoimmune encephalomyelitis. J. Immunol. 155:5003.
11. Gupta, S. K., T. Hassel, and J. P. Singh. 1995. A potent inhibitor of endothelial cell proliferation is generated by proteolytic cleavage of the chemokine platelet factor 4. Proc. Natl. Acad. Sci. USA 92:7799.
12. Zhou, Z., Y. J. Kim, K. Pollok, J. Hurtado, J. L. Lee, H. E. Broxmeyer, and B. S. Kwon. 1993. Macrophage inflammatory protein-1α rapidly modulates its receptors and inhibits the anti-CD3 mAb-mediated proliferation of T lymphocytes. J. Immunol. 151:4333.
13. Taub, D. D., S. M. Turcovski-Corrales, M. L. Key, D. L. Longo, and W. J. Murphy. 1996. Chemokines and T lymphocytes activation 1: B chemokines costimulate human T lymphocyte activation in vitro. J. Immunol. 156:2095.
14. Choe, H., M. Farzan, Y. Sun, N. Sullivan, B. Rollins, P. D. Ponath, L. Wu, C. R. Mackay, G. LaRosa, W. Newman, N. Gerard, C. Gerard, and J. Sodroski. 1996. The B-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates. Cell 85:1135.
15. Feng, Y., C. C. Broder, P. E. Kennedyu, and E. A. Berger. 1996. HIV-1 entry cofactor: functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor. Science 272:872.
16. Chang, Ming-shi, J. McNinch, C. Elias III, C. L. Manthey, D. Grosshans, T. Meng, T. Boone, and D. P. Andrew. 1997. Molecular cloning and functional characterization of a novel CC chemokine stimulated T cell cheomtactic protein (STCP-1) that specifically acts on activated T lymphocytes. J. Biol. Chem. 272:25229.
17. Godiska, R., D. Chantry, C. J. Raport, S. Sozzani, P. Allavena, D. Levitin, A. Mantovani, and P. Gray. 1997. Human macrophage derived chemokine (MDC), a novel chemoattractant for monocytes-derived dendritic cells and natural killer cells. J. Exp. Med. 185:1595.
18. Murphy, E., K. Shibuya, N. Hosken, P. Openshaw, V. Maino, K. Davis, K. Murphy, and A. O'Garra. 1997. Reversibility of T helper 1 and 2 populations is lost after long term stimulation. J. Exp. Med. 183:901.
19. Austrup, F., D. Vestweber, E. Borges, M. Lohning, R. Brauer, U. Herz, H. Renz, R. Hallman, A. Scheffold, A. Radbruch, and A. Hamman. 1997. P-and E-selectin mediate recruitment of T helper 1 but not T helper 2 cells into inflamed tissues. Nature 385:81.
20. Sallusto, F., C. R. Mackay, and A. Lanzavecchia. 1997. Selective expression of the eotaxin receptor CCR3 by human T helper 2 cells. Science 277:2005.
21. Sallusto, F., and A. Lanzavecchia. 1994. Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor α. J. Exp. Med. 179:1109.
22. Holland, P. M., R. D. Abramson, R. Watson, and D. H. Gelfand. 1991. Detection of specific polymerase chain reaction product by utilizing the 5′ to 3′ exonuclease activity of Thermus aquaticus DNA polymerase. Proc. Natl. Acad. Sci. USA 88:7276.
23. Forssmann, U., M. Uguccioni, P. Loetscher, C. A. Dahinden, H. Langen, M. Thelen, and M. Baggiolini. 1997. Eotaxin-2, a novel CC chemokine that is selective for the chemokine receptor CCR3 and acts like eotaxin on human eosinophil and basophilic leukocytes. J. Exp. Med. 185:2171.
24. Lukacs, N. W., S. W. Chensue, W. J. Karus, P. Lincoln, C. Keefer, R. M. Strieter, and S. L. Kunkel. 1997. C-C chemokines differentially alter interleukin 4 production from lymphocytes. Am. J. Pathol. 150:1861.
25. Kimata, H., A. Yoshida, C. Ishioka, M. Fujimoto, I. Lindley, and K. Furusho. 1996. RANTES and MIP-1a selectively enhance immunoglobulin (IgE) and IgG4 production by B lymphocytes. J. Exp. Med. 183:2397.
26. Gao, J. L., T. A. Wynn, Y. Chang, E. J. Lee, H. E. Broxmeyer, S. Cooper, H. L. Tiffany, H. Westphal, J. Kwon-Chung, and P. Murphy. 1997. Impaired host defense, hematopoiesis, granulomaous inflammation and type-1/type2 cytokine balance in mice lacking CC chemokine receptor 1. J. Exp. Med. 185:1959.
27. Boring, L., J. Gosling, S. W. Chensue, S. L. Kunkel, R. V. Farese, H. E. Broxmeyer, and I. F. Chara. 1997. Impaired monocyte migration and reduced type 1 (Th1) cytokine responses in C-C chemokine receptor 2 knock out mice. J. Clin. Invest. 100:2552.
28. Imai, T., M. Baba, M. Nishimura, M. Kahizaki, S. Takagi, and O. Yoshie. 1997. The T cell directed CC chemokine TARC is a highly specific biological ligand for CC chemokine receptor 4. J. Biol. Chem. 272:15036.
29. Imai, T., D. Chantry, C. J. Raport, C. L. Wood, M. Nishimura, R. Godiska, O. Yoshie, and P. W. Gray. 1998. Macrophage-derived chemokine is a functional ligand for chemokine receptor 4. J. Biol. Chem. 273:1764.
30. Luster, A. D., J. C. Unkeless, and J. V. Ravetch. 1985. Interferon gamma transcriptionally regulates an early response gene containing homology to platelet proteins. Nature 315:672.
31. Kaplan, G., A. D. Luster, G. Hancock, and Z. Cohn. 1987. The expression of a γ interferon-induced protein (IP-10) in delayed immune responses in human skin. J. Exp. Med. 166:1098.
32. Bernardini, G., J. Hedrick, S. Sozzani, W. Luini, G. Spinetti, M. Weiss, S. Menon, A. Zlotnik, A. Mantovani, A. Santoni, and M. Napolitano. 1998. Identification of the chemokines TARC and macrophage inflammatory protein-1β as novel functional ligands of the CCR8 receptor. Eur. J. Immunol. 28:582.
33. Xhou, Y., T. Kurihara, R. P. Ryseck, Y. Yang, C. Ryan, J. Leroy, G. Warr, and R. Bravo. 1998. Impaired macrophage function and enhanced T cell dependent immune response in mice lacking CCR5, the mouse homologue of the major HIV-1 coreceptor. J. Immunol. 160:4018.
34. Bleul, C., L. Wu, J. A. Hoxie, T. A. Springer, and C. R. Mackay. 1997. The HIV coreceptors CXCR4 and CCR5 are differentially expressed and regulated on human T lymphocytes. Proc. Natl. Acad. Sci. USA 94:1925.
35. Adema, G. J., F. Hartgers, R. Verstraten, E. de Vries, G. Marland, S. Menon, J. Foster, Y. Xu, P. Nooyen, T. McClanahan, K. B. Bacon, and C. G. Figdor. 1997. A dendritic cell derived CC chemokine that preferentially attracts naive T cells. Nature 387:713.
36. Qin, S., G. LaRosa, J. J. Campbell, H. Smith-Heath, N. Kassam, X. Shi, L. Zeng, E. C. Butcher, and C. R. Mackay. 1996. Expression of monocyte chemoattractant protein-1 and IL-8 receptors on subsets of T cells: correlation with transendothelial chemotactic potential. Eur. J. Immunol. 26:640.
37. Robinson, D. S., Q. Hamid, S. Ying, A. Tsicopoulos, J. Barkans, A. M. Bentley, C. Corrigan, S. R. Durham, and B. Kay. 1992. Predominant TH2 like bronchiolar T lymphocyte population in atopic asthma. N. Engl. J. Med. 326:298.
38. Crimi, E., D. Gaffi, E. Frittoli, B. Borgonova, and S. E. Buratero. 1997. Depletion of circulating allergan-specific TH2 T lymphocytes after allergan expsoure in asthma. J. Allergy. Clin. Immunol. 99:788.
39. Weinblatt, M. E., P. J. Maddison, K. J. Bulpitt, B. L. Hazleman, M. B. Urowitz, R. D. Sturrock, J. S. Coblyn, A. L. Maier, W. R. Spreen, V. K. Manna, and J. M. Johnston. 1997. CAMPATH-1H, a humanized monoclonal antibody in refractory rheumatoid arthritis. Arthritis Rheum. 38:1589.
40. + T cell counts. Arthritis Rheum. 37:834.
41. Gonzalo, J. A., C. M. Lloyd, L. Kremer, E. Finger, C. Martinez-A, M. H. Siegelman, M. Cybulsky, and J. C. Guitierrez-Ramos. 1996. Eosinophil recruitment to the lung in a murine model of allergic inflammation: the role of T cells, chemokines and adhesion receptors. J. Clin. Invest. 98:2332.
42. Bonecchi, R., G. Bianchi, P. P. Bordignon, D. D'Ambrosio, R. Lang, A. Borsatti, S. Sozzani, P. Allavena, P. W. Gray, A. Mantovani, and F. Sinigaglia. 1998. Differential expression of chemokine receptors and chemotactic responsiveness of T helper (Th1s) and Th2s. J. Exp. Med. 187:129.
43. Sallusto, F., D. Lenig, C. Mackay, and A. Lanzavecchia. 1998. Flexible programs of chemokine receptor expression on human polarized T helper 1 and 2 lymphocytes. J. Exp. Med. 187:875.