메뉴 건너뛰기




Volumn 143, Issue 6, 2012, Pages

Liver progenitor cells yield functional hepatocytes in response to chronic liver injury in mice

Author keywords

Differentiation; Liver Disease; Liver Regeneration; Mouse Model

Indexed keywords

1,4 DIHYDRO 2,4,6 TRIMETHYL 3,5 PYRIDINEDICARBOXYLIC ACID DIETHYL ESTER; CARBON TETRACHLORIDE; CRE RECOMBINASE; GLYCOGEN; LAMININ; OSTEOPONTIN; TAMOXIFEN; YELLOW FLUORESCENT PROTEIN;

EID: 84869751765     PISSN: 00165085     EISSN: 15280012     Source Type: Journal    
DOI: 10.1053/j.gastro.2012.08.024     Document Type: Article
Times cited : (294)

References (44)
  • 1
    • 0001888629 scopus 로고    scopus 로고
    • Liver stem cells
    • C.S. Potten, Academic Press London
    • J. Grisham, S. Thorgeirsson Liver stem cells C.S. Potten, Stem cells 1997 Academic Press London 233 282
    • (1997) Stem Cells , pp. 233-282
    • Grisham, J.1    Thorgeirsson, S.2
  • 2
    • 0037213389 scopus 로고    scopus 로고
    • The role of hepatocytes and oval cells in liver regeneration and repopulation
    • N. Fausto, J.S. Campbell The role of hepatocytes and oval cells in liver regeneration and repopulation Mech Dev 120 2003 117 130
    • (2003) Mech Dev , vol.120 , pp. 117-130
    • Fausto, N.1    Campbell, J.S.2
  • 3
    • 0036109627 scopus 로고    scopus 로고
    • Liver stem cells and model systems for liver repopulation
    • D.A. Shafritz, M.D. Dabeva Liver stem cells and model systems for liver repopulation J Hepatol 36 2002 552 564
    • (2002) J Hepatol , vol.36 , pp. 552-564
    • Shafritz, D.A.1    Dabeva, M.D.2
  • 6
    • 66149112853 scopus 로고    scopus 로고
    • Locating the stem cell niche and tracing hepatocyte lineages in human liver
    • T.G. Fellous, S. Islam, P.J. Tadrous Locating the stem cell niche and tracing hepatocyte lineages in human liver Hepatology 49 2009 1655 1663
    • (2009) Hepatology , vol.49 , pp. 1655-1663
    • Fellous, T.G.1    Islam, S.2    Tadrous, P.J.3
  • 7
    • 78651228289 scopus 로고    scopus 로고
    • Continuous cell supply from a Sox9-expressing progenitor zone in adult liver, exocrine pancreas and intestine
    • K. Furuyama, Y. Kawaguchi, H. Akiyama Continuous cell supply from a Sox9-expressing progenitor zone in adult liver, exocrine pancreas and intestine Nat Genet 43 2011 34 41
    • (2011) Nat Genet , vol.43 , pp. 34-41
    • Furuyama, K.1    Kawaguchi, Y.2    Akiyama, H.3
  • 8
    • 80053610191 scopus 로고    scopus 로고
    • Embryonic ductal plate cells give rise to cholangiocytes, periportal hepatocytes, and adult liver progenitor cells
    • R. Carpentier, R. Español-Suñer, N. Van Hul Embryonic ductal plate cells give rise to cholangiocytes, periportal hepatocytes, and adult liver progenitor cells Gastroenterology 141 2011 1432 1438
    • (2011) Gastroenterology , vol.141 , pp. 1432-1438
    • Carpentier, R.1    Español-Suñer, R.2    Van Hul, N.3
  • 9
    • 79960726270 scopus 로고    scopus 로고
    • Contributions of new hepatocyte lineages to liver growth, maintenance, and regeneration in mice
    • S.V. Iverson, K.M. Comstock, J.A. Kundert Contributions of new hepatocyte lineages to liver growth, maintenance, and regeneration in mice Hepatology 54 2011 655 663
    • (2011) Hepatology , vol.54 , pp. 655-663
    • Iverson, S.V.1    Comstock, K.M.2    Kundert, J.A.3
  • 10
    • 84055199890 scopus 로고    scopus 로고
    • Fate tracing of mature hepatocytes in mouse liver homeostasis and regeneration
    • Y. Malato, S. Naqvi, N. Schurmann Fate tracing of mature hepatocytes in mouse liver homeostasis and regeneration J Clin Invest 121 2011 4850 4860
    • (2011) J Clin Invest , vol.121 , pp. 4850-4860
    • Malato, Y.1    Naqvi, S.2    Schurmann, N.3
  • 12
    • 80055051680 scopus 로고    scopus 로고
    • Ductular reactions in human liver: Diversity at the interface
    • A.S. Gouw, A.D. Clouston, N.D. Theise Ductular reactions in human liver: diversity at the interface Hepatology 54 2011 1853 1863
    • (2011) Hepatology , vol.54 , pp. 1853-1863
    • Gouw, A.S.1    Clouston, A.D.2    Theise, N.D.3
  • 13
    • 77950618927 scopus 로고    scopus 로고
    • The histogenesis of regenerative nodules in human liver cirrhosis
    • W.R. Lin, S.N. Lim, S.A. McDonald The histogenesis of regenerative nodules in human liver cirrhosis Hepatology 51 2010 1017 1026
    • (2010) Hepatology , vol.51 , pp. 1017-1026
    • Lin, W.R.1    Lim, S.N.2    McDonald, S.A.3
  • 14
    • 79952230767 scopus 로고    scopus 로고
    • Epithelial cell adhesion molecule (EpCAM) marks hepatocytes newly derived from stem/progenitor cells in humans
    • S.M. Yoon, D. Gerasimidou, R. Kuwahara Epithelial cell adhesion molecule (EpCAM) marks hepatocytes newly derived from stem/progenitor cells in humans Hepatology 53 2011 964 973
    • (2011) Hepatology , vol.53 , pp. 964-973
    • Yoon, S.M.1    Gerasimidou, D.2    Kuwahara, R.3
  • 15
    • 79958051227 scopus 로고    scopus 로고
    • Prospective isolation of a bipotential clonogenic liver progenitor cell in adult mice
    • C. Dorrell, L. Erker, J. Schug Prospective isolation of a bipotential clonogenic liver progenitor cell in adult mice Genes Dev 25 2011 1193 1203
    • (2011) Genes Dev , vol.25 , pp. 1193-1203
    • Dorrell, C.1    Erker, L.2    Schug, J.3
  • 16
    • 79958066222 scopus 로고    scopus 로고
    • Foxl1-Cre-marked adult hepatic progenitors have clonogenic and bilineage differentiation potential
    • S. Shin, G. Walton, R. Aoki Foxl1-Cre-marked adult hepatic progenitors have clonogenic and bilineage differentiation potential Genes Dev 25 2011 1185 1192
    • (2011) Genes Dev , vol.25 , pp. 1185-1192
    • Shin, S.1    Walton, G.2    Aoki, R.3
  • 17
    • 68349094342 scopus 로고    scopus 로고
    • Potential hepatic stem cells reside in EpCAM+ cells of normal and injured mouse liver
    • M. Okabe, Y. Tsukahara, M. Tanaka Potential hepatic stem cells reside in EpCAM+ cells of normal and injured mouse liver Development 136 2009 1951 1960
    • (2009) Development , vol.136 , pp. 1951-1960
    • Okabe, M.1    Tsukahara, Y.2    Tanaka, M.3
  • 18
    • 39549111466 scopus 로고    scopus 로고
    • Identification of adult hepatic progenitor cells capable of repopulating injured rat liver
    • M.I. Yovchev, P.N. Grozdanov, H. Zhou Identification of adult hepatic progenitor cells capable of repopulating injured rat liver Hepatology 47 2008 636 647
    • (2008) Hepatology , vol.47 , pp. 636-647
    • Yovchev, M.I.1    Grozdanov, P.N.2    Zhou, H.3
  • 19
    • 0038010055 scopus 로고    scopus 로고
    • Differentiation of putative hepatic stem cells derived from adult rats into mature hepatocytes in the presence of epidermal growth factor and hepatocyte growth factor
    • Z.P. He, W.Q. Tan, Y.F. Tang Differentiation of putative hepatic stem cells derived from adult rats into mature hepatocytes in the presence of epidermal growth factor and hepatocyte growth factor Differentiation 71 2003 281 290
    • (2003) Differentiation , vol.71 , pp. 281-290
    • He, Z.P.1    Tan, W.Q.2    Tang, Y.F.3
  • 20
    • 33750336747 scopus 로고    scopus 로고
    • Defective hepatic regeneration after partial hepatectomy in leptin-deficient mice is not rescued by exogenous leptin
    • I.A. Leclercq, M. Vansteenberghe, V.B. Lebrun Defective hepatic regeneration after partial hepatectomy in leptin-deficient mice is not rescued by exogenous leptin Lab Invest 86 2006 1161 1171
    • (2006) Lab Invest , vol.86 , pp. 1161-1171
    • Leclercq, I.A.1    Vansteenberghe, M.2    Lebrun, V.B.3
  • 21
    • 3042856262 scopus 로고    scopus 로고
    • Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus
    • S. Srinivas, T. Watanabe, C.S. Lin Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus BMC Dev Biol 1 2001 4
    • (2001) BMC Dev Biol , vol.1 , pp. 4
    • Srinivas, S.1    Watanabe, T.2    Lin, C.S.3
  • 22
    • 66149109566 scopus 로고    scopus 로고
    • Relation between liver progenitor cell expansion and extracellular matrix deposition in a CDE-induced murine model of chronic liver injury
    • N.K. Van Hul, J. Abarca-Quinones, C. Sempoux Relation between liver progenitor cell expansion and extracellular matrix deposition in a CDE-induced murine model of chronic liver injury Hepatology 49 2009 1625 1635
    • (2009) Hepatology , vol.49 , pp. 1625-1635
    • Van Hul, N.K.1    Abarca-Quinones, J.2    Sempoux, C.3
  • 23
    • 80053278784 scopus 로고    scopus 로고
    • Kupffer cells influence parenchymal invasion and phenotypic orientation, but not the proliferation, of liver progenitor cells in a murine model of liver injury
    • N. Van Hul, N. Lanthier, R. Español-Suñer Kupffer cells influence parenchymal invasion and phenotypic orientation, but not the proliferation, of liver progenitor cells in a murine model of liver injury Am J Pathol 179 2011 1839 1850
    • (2011) Am J Pathol , vol.179 , pp. 1839-1850
    • Van Hul, N.1    Lanthier, N.2    Español-Suñer, R.3
  • 24
    • 2342502028 scopus 로고    scopus 로고
    • 2-acetylaminofluorene dose-dependent differentiation of rat oval cells into hepatocytes: Confocal and electron microscopic studies
    • S. Paku, P. Nagy, L. Kopper 2-acetylaminofluorene dose-dependent differentiation of rat oval cells into hepatocytes: confocal and electron microscopic studies Hepatology 39 2004 1353 1361
    • (2004) Hepatology , vol.39 , pp. 1353-1361
    • Paku, S.1    Nagy, P.2    Kopper, L.3
  • 25
    • 20444462270 scopus 로고    scopus 로고
    • Role of connective tissue growth factor in oval cell response during liver regeneration after 2-AAF/PHx in rats
    • L. Pi, S.H. Oh, T. Shupe Role of connective tissue growth factor in oval cell response during liver regeneration after 2-AAF/PHx in rats Gastroenterology 128 2005 2077 2088
    • (2005) Gastroenterology , vol.128 , pp. 2077-2088
    • Pi, L.1    Oh, S.H.2    Shupe, T.3
  • 26
    • 77951728697 scopus 로고    scopus 로고
    • Characterisation of a stereotypical cellular and extracellular adult liver progenitor cell niche in rodents and diseased human liver
    • S. Lorenzini, T.G. Bird, L. Boulter Characterisation of a stereotypical cellular and extracellular adult liver progenitor cell niche in rodents and diseased human liver Gut 59 2010 645 654
    • (2010) Gut , vol.59 , pp. 645-654
    • Lorenzini, S.1    Bird, T.G.2    Boulter, L.3
  • 27
    • 79951539242 scopus 로고    scopus 로고
    • Sox9+ ductal cells are multipotent progenitors throughout development but do not produce new endocrine cells in the normal or injured adult pancreas
    • J.L. Kopp, C.L. Dubois, A.E. Schaffer Sox9+ ductal cells are multipotent progenitors throughout development but do not produce new endocrine cells in the normal or injured adult pancreas Development 138 2011 653 665
    • (2011) Development , vol.138 , pp. 653-665
    • Kopp, J.L.1    Dubois, C.L.2    Schaffer, A.E.3
  • 28
    • 47549119127 scopus 로고    scopus 로고
    • A CK19(CreERT) knockin mouse line allows for conditional DNA recombination in epithelial cells in multiple endodermal organs
    • A.L. Means, Y. Xu, A. Zhao A CK19(CreERT) knockin mouse line allows for conditional DNA recombination in epithelial cells in multiple endodermal organs Genesis 46 2008 318 323
    • (2008) Genesis , vol.46 , pp. 318-323
    • Means, A.L.1    Xu, Y.2    Zhao, A.3
  • 29
    • 0037853158 scopus 로고    scopus 로고
    • Regeneration of hepatocyte 'buds' in cirrhosis from intrabiliary stem cells
    • O. Falkowski, H.J. An, I.A. Ianus Regeneration of hepatocyte 'buds' in cirrhosis from intrabiliary stem cells J Hepatol 39 2003 357 364
    • (2003) J Hepatol , vol.39 , pp. 357-364
    • Falkowski, O.1    An, H.J.2    Ianus, I.A.3
  • 30
    • 14244252656 scopus 로고    scopus 로고
    • Transdifferentiation of rat hepatocytes into biliary cells after bile duct ligation and toxic biliary injury
    • G.K. Michalopoulos, L. Barua, W.C. Bowen Transdifferentiation of rat hepatocytes into biliary cells after bile duct ligation and toxic biliary injury Hepatology 41 2005 535 544
    • (2005) Hepatology , vol.41 , pp. 535-544
    • Michalopoulos, G.K.1    Barua, L.2    Bowen, W.C.3
  • 32
    • 77950597707 scopus 로고    scopus 로고
    • Hepatocytes do not undergo epithelial-mesenchymal transition in liver fibrosis in mice
    • K. Taura, K. Miura, K. Iwaisako Hepatocytes do not undergo epithelial-mesenchymal transition in liver fibrosis in mice Hepatology 51 2010 1027 1036
    • (2010) Hepatology , vol.51 , pp. 1027-1036
    • Taura, K.1    Miura, K.2    Iwaisako, K.3
  • 33
    • 77956158103 scopus 로고    scopus 로고
    • Genetic labeling does not detect epithelial-to-mesenchymal transition of cholangiocytes in liver fibrosis in mice
    • D. Scholten, C.H. Osterreicher, A. Scholten Genetic labeling does not detect epithelial-to-mesenchymal transition of cholangiocytes in liver fibrosis in mice Gastroenterology 139 2010 987 998
    • (2010) Gastroenterology , vol.139 , pp. 987-998
    • Scholten, D.1    Osterreicher, C.H.2    Scholten, A.3
  • 34
    • 79955123951 scopus 로고    scopus 로고
    • Lineage tracing demonstrates no evidence of cholangiocyte epithelial-to-mesenchymal transition in murine models of hepatic fibrosis
    • A.S. Chu, R. Diaz, J.J. Hui Lineage tracing demonstrates no evidence of cholangiocyte epithelial-to-mesenchymal transition in murine models of hepatic fibrosis Hepatology 53 2011 1685 1695
    • (2011) Hepatology , vol.53 , pp. 1685-1695
    • Chu, A.S.1    Diaz, R.2    Hui, J.J.3
  • 35
    • 84859614232 scopus 로고    scopus 로고
    • Macrophage-derived Wnt opposes Notch signaling to specify hepatic progenitor cell fate in chronic liver disease
    • L. Boulter, O. Govaere, T.G. Bird Macrophage-derived Wnt opposes Notch signaling to specify hepatic progenitor cell fate in chronic liver disease Nat Med 18 2012 572 579
    • (2012) Nat Med , vol.18 , pp. 572-579
    • Boulter, L.1    Govaere, O.2    Bird, T.G.3
  • 36
    • 0034953832 scopus 로고    scopus 로고
    • Iloprost suppresses connective tissue growth factor production in fibroblasts and in the skin of scleroderma patients
    • R. Stratton, X. Shiwen, G. Martini Iloprost suppresses connective tissue growth factor production in fibroblasts and in the skin of scleroderma patients J Clin Invest 108 2001 241 250
    • (2001) J Clin Invest , vol.108 , pp. 241-250
    • Stratton, R.1    Shiwen, X.2    Martini, G.3
  • 37
    • 0036883881 scopus 로고    scopus 로고
    • Prostacyclin derivatives prevent the fibrotic response to TGF-beta by inhibiting the Ras/MEK/ERK pathway
    • R. Stratton, V. Rajkumar, M. Ponticos Prostacyclin derivatives prevent the fibrotic response to TGF-beta by inhibiting the Ras/MEK/ERK pathway FASEB J 16 2002 1949 1951
    • (2002) FASEB J , vol.16 , pp. 1949-1951
    • Stratton, R.1    Rajkumar, V.2    Ponticos, M.3
  • 38
    • 0031664853 scopus 로고    scopus 로고
    • A new logic for DNA engineering using recombination in Escherichia coli
    • Y. Zhang, F. Buchholz, J.P. Muyrers A new logic for DNA engineering using recombination in Escherichia coli Nat Genet 20 1998 123 128
    • (1998) Nat Genet , vol.20 , pp. 123-128
    • Zhang, Y.1    Buchholz, F.2    Muyrers, J.P.3
  • 39
    • 0033668496 scopus 로고    scopus 로고
    • DNA cloning by homologous recombination in Escherichia coli
    • Y. Zhang, J.P. Muyrers, G. Testa, A.F. Stewart DNA cloning by homologous recombination in Escherichia coli Nat Biotechnol 18 2000 1314 1317
    • (2000) Nat Biotechnol , vol.18 , pp. 1314-1317
    • Zhang, Y.1    Muyrers, J.P.2    Testa, G.3    Stewart, A.F.4
  • 40
    • 34250315750 scopus 로고    scopus 로고
    • A recombineering based approach for high-throughput conditional knockout targeting vector construction
    • W. Chan, N. Costantino, R. Li, S.C. Lee A recombineering based approach for high-throughput conditional knockout targeting vector construction Nucleic Acids Res 35 2007 e64
    • (2007) Nucleic Acids Res , vol.35 , pp. 64
    • Chan, W.1    Costantino, N.2    Li, R.3    Lee, S.C.4
  • 41
    • 0036158916 scopus 로고    scopus 로고
    • Codon-improved Cre recombinase (iCre) expression in the mouse
    • D.R. Shimshek, J. Kim, M.R. Hubner Codon-improved Cre recombinase (iCre) expression in the mouse Genesis 32 2002 19 26
    • (2002) Genesis , vol.32 , pp. 19-26
    • Shimshek, D.R.1    Kim, J.2    Hubner, M.R.3
  • 42
    • 79251481160 scopus 로고    scopus 로고
    • A mouse tool for conditional mutagenesis in ovarian granulosa cells
    • B. Grabner, L. Blaas, M. Musteanu A mouse tool for conditional mutagenesis in ovarian granulosa cells Genesis 48 2010 612 617
    • (2010) Genesis , vol.48 , pp. 612-617
    • Grabner, B.1    Blaas, L.2    Musteanu, M.3
  • 43
    • 0035308590 scopus 로고    scopus 로고
    • A highly efficient Escherichia coli-based chromosome engineering system adapted for recombinogenic targeting and subcloning of BAC DNA
    • E.C. Lee, D. Yu, de Velasco Martinez A highly efficient Escherichia coli-based chromosome engineering system adapted for recombinogenic targeting and subcloning of BAC DNA Genomics 73 2001 56 65
    • (2001) Genomics , vol.73 , pp. 56-65
    • Lee, E.C.1    Yu, D.2    Martinez, D.V.3
  • 44
    • 66149109566 scopus 로고    scopus 로고
    • Relation between liver progenitor cell expansion and extracellular matrix deposition in a CDE-induced murine model of chronic liver injury
    • N.K. Van Hul, J. Abarca-Quinones, C. Sempoux Relation between liver progenitor cell expansion and extracellular matrix deposition in a CDE-induced murine model of chronic liver injury Hepatology 49 2009 1625 1635
    • (2009) Hepatology , vol.49 , pp. 1625-1635
    • Van Hul, N.K.1    Abarca-Quinones, J.2    Sempoux, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.