The pan-ErbB negative regulator lrig1 is an intestinal stem cell marker that functions as a tumor suppressor

Cell

Volumn 149, Issue 1, 2012, Pages 146-158

  Powell, Anne E ^a   Wang, Yang ^a   Li, Yina ^a   Poulin, Emily J ^a   Means, Anna L ^a   Washington, Mary K ^a   Higginbotham, James N ^a   Juchheim, Alwin ^b   Prasad, Nripesh ^c   Levy, Shawn E ^c   Guo, Yan ^a   Shyr, Yu ^a   Aronow, Bruce J ^d   Haigis, Kevin M ^b   Franklin, Jeffrey L ^a   Coffey, Robert J ^a,e  

^a VANDERBILT UNIVERSITY   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c HUDSONALPHA INSTITUTE FOR BIOTECHNOLOGY   (United States)

^d CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^e DEPARTMENT OF VETERANS AFFAIRS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TUBULIN; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPIDERMAL GROWTH FACTOR RECEPTOR 3; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN LRIG1; REGULATOR PROTEIN; TRANSCRIPTOME; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APC GENE; ARTICLE; CELL CYCLE; CELL DIVISION; CELL LINEAGE; CELL POPULATION; CELL PROLIFERATION; COLON ADENOMA; CONTROLLED STUDY; DUODENUM TUMOR; INTESTINAL STEM CELL; INTESTINE CRYPT; LRIG1 GENE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; STEM CELL; TUMOR SUPPRESSOR GENE; UPREGULATION;

EID: 84859196824     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2012.02.042     Document Type: Article

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