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Volumn 38, Issue 3, 2016, Pages 293-307

Trp channels and itch

Author keywords

DRG neurons; GPCR; Itch; Skin; Trp channel

Indexed keywords

1 (2 BROMOPHENYL) 3 [1 (5 TRIFLUOROMETHYL 2 PYRIDINYL) 3 PYRROLIDINYL]UREA; CYTOKINE RECEPTOR; ENDOTHELIN RECEPTOR; G PROTEIN COUPLED RECEPTOR; HISTAMINE RECEPTOR; INTERLEUKIN 31 RECEPTOR; LEUKOTRIENE B4 RECEPTOR; LEUKOTRIENE B4 RECEPTOR 2; MAS RELATED G PROTEIN COUPLED RECEPTOR; PAC 14028; PROTEINASE ACTIVATED RECEPTOR 1; PROTEINASE ACTIVATED RECEPTOR 2; PROTEINASE ACTIVATED RECEPTOR 3; PROTEINASE ACTIVATED RECEPTOR 4; SEROTONIN RECEPTOR; THYMIC STROMAL LYMPHOPOIETIN RECEPTOR; TOLL LIKE RECEPTOR; TRANSIENT RECEPTOR POTENTIAL CHANNEL; UNCLASSIFIED DRUG; VANILLOID RECEPTOR 1 ANTAGONIST; ANTIPRURITIC AGENT;

EID: 84942058704     PISSN: 18632297     EISSN: 18632300     Source Type: Journal    
DOI: 10.1007/s00281-015-0530-4     Document Type: Review
Times cited : (67)

References (184)
  • 1
    • 33745684571 scopus 로고    scopus 로고
    • The neurobiology of itch
    • COI: 1:CAS:528:DC%2BD28XmtVSgtrg%3D, PID: 16791143
    • Ikoma A, Steinhoff M, Ständer S et al (2006) The neurobiology of itch. Nat Rev Neurosci 7:535–547
    • (2006) Nat Rev Neurosci , vol.7 , pp. 535-547
    • Ikoma, A.1    Steinhoff, M.2    Ständer, S.3
  • 2
    • 35348913148 scopus 로고    scopus 로고
    • Clinical classification of itch: a position paper of the International Forum for the Study of Itch
    • PID: 17598029
    • Ständer S, Weisshaar E, Mettang T et al (2007) Clinical classification of itch: a position paper of the International Forum for the Study of Itch. Acta Derm Venereol 87:291–294
    • (2007) Acta Derm Venereol , vol.87 , pp. 291-294
    • Ständer, S.1    Weisshaar, E.2    Mettang, T.3
  • 3
    • 84884131951 scopus 로고    scopus 로고
    • Neural processing of itch
    • COI: 1:CAS:528:DC%2BC3sXht12itrnN, PID: 23891755
    • Akiyama T, Carstens E (2013) Neural processing of itch. Neuroscience 250:697–714
    • (2013) Neuroscience , vol.250 , pp. 697-714
    • Akiyama, T.1    Carstens, E.2
  • 4
    • 0006021465 scopus 로고
    • Zur Physiologie der Juckempfindung
    • Von Frey M (1922) Zur Physiologie der Juckempfindung. Arch Neerl Physiol 142–145
    • (1922) Arch Neerl Physiol , pp. 142-145
    • Von Frey, M.1
  • 5
    • 0001013340 scopus 로고
    • Vascular reactions of the skin to injury. Part X The intervention of a chemical stimulus illustrated especially by the flare. The response to faradism - Google Search
    • Lewis T, Grant RT, Marvin HM (1927) Vascular reactions of the skin to injury. Part X The intervention of a chemical stimulus illustrated especially by the flare. The response to faradism - Google Search. Heart 139–160
    • (1927) Heart , pp. 139-160
    • Lewis, T.1    Grant, R.T.2    Marvin, H.M.3
  • 6
    • 78049303517 scopus 로고    scopus 로고
    • An itch to be scratched
    • COI: 1:CAS:528:DC%2BC3cXhtlKkt7vM, PID: 21040839
    • Patel KN, Dong X (2010) An itch to be scratched. Neuron 68:334–339
    • (2010) Neuron , vol.68 , pp. 334-339
    • Patel, K.N.1    Dong, X.2
  • 7
    • 0033558529 scopus 로고    scopus 로고
    • Cutaneous sensory spots and the “law of specific nerve energies”: history and development of ideas
    • COI: 1:STN:280:DyaK1M3pvFOhsw%3D%3D, PID: 10372506
    • Norrsell U, Finger S, Lajonchere C (1999) Cutaneous sensory spots and the “law of specific nerve energies”: history and development of ideas. Brain Res Bull 48:457–465
    • (1999) Brain Res Bull , vol.48 , pp. 457-465
    • Norrsell, U.1    Finger, S.2    Lajonchere, C.3
  • 8
    • 70349317480 scopus 로고    scopus 로고
    • Cellular basis of itch sensation
    • COI: 1:CAS:528:DC%2BD1MXhtFanurrN, PID: 19661382
    • Sun Y-G, Zhao Z-Q, Meng X-L et al (2009) Cellular basis of itch sensation. Science 325:1531–1534
    • (2009) Science , vol.325 , pp. 1531-1534
    • Sun, Y.-G.1    Zhao, Z.-Q.2    Meng, X.-L.3
  • 9
    • 72249113172 scopus 로고    scopus 로고
    • Sensory neuron-specific GPCR Mrgprs are itch receptors mediating chloroquine-induced pruritus
    • PID: 20004959
    • Liu Q, Tang Z, Surdenikova L et al (2009) Sensory neuron-specific GPCR Mrgprs are itch receptors mediating chloroquine-induced pruritus. Cell 139:1353–1365
    • (2009) Cell , vol.139 , pp. 1353-1365
    • Liu, Q.1    Tang, Z.2    Surdenikova, L.3
  • 10
    • 79955385137 scopus 로고    scopus 로고
    • TRPA1 is required for histamine-independent, Mas-related G protein-coupled receptor-mediated itch
    • COI: 1:CAS:528:DC%2BC3MXktFahsbc%3D, PID: 21460831
    • Wilson SR, Gerhold KA, Bifolck-Fisher A et al (2011) TRPA1 is required for histamine-independent, Mas-related G protein-coupled receptor-mediated itch. Nat Neurosci 14:595–602
    • (2011) Nat Neurosci , vol.14 , pp. 595-602
    • Wilson, S.R.1    Gerhold, K.A.2    Bifolck-Fisher, A.3
  • 11
    • 0037541581 scopus 로고    scopus 로고
    • Chemical response pattern of different classes of C-nociceptors to pruritogens and algogens
    • COI: 1:CAS:528:DC%2BD3sXksFSks7w%3D, PID: 12611975
    • Schmelz M, Schmidt R, Weidner C et al (2003) Chemical response pattern of different classes of C-nociceptors to pruritogens and algogens. J Neurophysiol 89:2441–2448
    • (2003) J Neurophysiol , vol.89 , pp. 2441-2448
    • Schmelz, M.1    Schmidt, R.2    Weidner, C.3
  • 12
    • 34548632601 scopus 로고    scopus 로고
    • TRP channels
    • COI: 1:CAS:528:DC%2BD2sXhtVehtb%2FJ, PID: 17579562
    • Venkatachalam K, Montell C (2007) TRP channels. Annu Rev Biochem 76:387–417
    • (2007) Annu Rev Biochem , vol.76 , pp. 387-417
    • Venkatachalam, K.1    Montell, C.2
  • 13
    • 33645297168 scopus 로고    scopus 로고
    • An introduction to TRP channels
    • COI: 1:CAS:528:DC%2BD28XksFWksL8%3D, PID: 16460286
    • Ramsey IS, Delling M, Clapham DE (2006) An introduction to TRP channels. Annu Rev Physiol 68:619–647
    • (2006) Annu Rev Physiol , vol.68 , pp. 619-647
    • Ramsey, I.S.1    Delling, M.2    Clapham, D.E.3
  • 14
    • 84885827972 scopus 로고    scopus 로고
    • TRP channels and pain
    • COI: 1:CAS:528:DC%2BC3sXhvFSqurfK, PID: 24099085
    • Julius D (2013) TRP channels and pain. Annu Rev Cell Dev Biol 29:355–384
    • (2013) Annu Rev Cell Dev Biol , vol.29 , pp. 355-384
    • Julius, D.1
  • 15
    • 25444482429 scopus 로고    scopus 로고
    • Mammalian G proteins and their cell type specific functions
    • COI: 1:CAS:528:DC%2BD2MXhtFeqsr3P, PID: 16183910
    • Wettschureck N, Offermanns S (2005) Mammalian G proteins and their cell type specific functions. Physiol Rev 85:1159–1204
    • (2005) Physiol Rev , vol.85 , pp. 1159-1204
    • Wettschureck, N.1    Offermanns, S.2
  • 16
    • 84964641636 scopus 로고
    • The blood vessels of the human skin and their responses
    • MacDermot HE (1927) The blood vessels of the human skin and their responses. Can Med Assoc J 17:1574
    • (1927) Can Med Assoc J , vol.17 , pp. 1574
    • MacDermot, H.E.1
  • 17
    • 0019921539 scopus 로고
    • Histamine receptors in human skin: indirect evidence
    • COI: 1:CAS:528:DyaL3sXmtVY%3D, PID: 7138777
    • Greaves MW, Davies MG (1982) Histamine receptors in human skin: indirect evidence. Br J Dermatol 107(Suppl):101–105
    • (1982) Br J Dermatol , vol.107 , pp. 101-105
    • Greaves, M.W.1    Davies, M.G.2
  • 18
    • 0032587894 scopus 로고    scopus 로고
    • Participation of histamine H1 and H2 receptors in passive cutaneous anaphylaxis-induced scratching behavior in ICR mice
    • COI: 1:CAS:528:DyaK1MXhsVWnt74%3D, PID: 10079012
    • Inagaki N, Nakamura N, Nagao M et al (1999) Participation of histamine H1 and H2 receptors in passive cutaneous anaphylaxis-induced scratching behavior in ICR mice. Eur J Pharmacol 367:361–371
    • (1999) Eur J Pharmacol , vol.367 , pp. 361-371
    • Inagaki, N.1    Nakamura, N.2    Nagao, M.3
  • 19
    • 67650494652 scopus 로고    scopus 로고
    • TRPV1-expressing primary afferents generate behavioral responses to pruritogens via multiple mechanisms
    • COI: 1:CAS:528:DC%2BD1MXptVWlu7w%3D, PID: 19564617
    • Imamachi N, Park GH, Lee H et al (2009) TRPV1-expressing primary afferents generate behavioral responses to pruritogens via multiple mechanisms. Proc Natl Acad Sci U S A 106:11330–11335
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 11330-11335
    • Imamachi, N.1    Park, G.H.2    Lee, H.3
  • 20
    • 84879651573 scopus 로고    scopus 로고
    • Activity-dependent silencing reveals functionally distinct itch-generating sensory neurons
    • COI: 1:CAS:528:DC%2BC3sXnvVSiu7o%3D, PID: 23685721
    • Roberson DP, Gudes S, Sprague JM et al (2013) Activity-dependent silencing reveals functionally distinct itch-generating sensory neurons. Nat Neurosci 16:910–918
    • (2013) Nat Neurosci , vol.16 , pp. 910-918
    • Roberson, D.P.1    Gudes, S.2    Sprague, J.M.3
  • 21
    • 2342466078 scopus 로고    scopus 로고
    • Histamine-induced Ca(2+) influx via the PLA(2)/lipoxygenase/TRPV1 pathway in rat sensory neurons
    • COI: 1:CAS:528:DC%2BD2cXjvVGlu7s%3D, PID: 15135918
    • Kim BM, Lee SH, Shim WS, Oh U (2004) Histamine-induced Ca(2+) influx via the PLA(2)/lipoxygenase/TRPV1 pathway in rat sensory neurons. Neurosci Lett 361:159–162
    • (2004) Neurosci Lett , vol.361 , pp. 159-162
    • Kim, B.M.1    Lee, S.H.2    Shim, W.S.3    Oh, U.4
  • 22
    • 33847400543 scopus 로고    scopus 로고
    • TRPV1 mediates histamine-induced itching via the activation of phospholipase A2 and 12-lipoxygenase
    • COI: 1:CAS:528:DC%2BD2sXjsVymsL8%3D, PID: 17329430
    • Shim W-S, Tak M-H, Lee M-H et al (2007) TRPV1 mediates histamine-induced itching via the activation of phospholipase A2 and 12-lipoxygenase. J Neurosci 27:2331–2337
    • (2007) J Neurosci , vol.27 , pp. 2331-2337
    • Shim, W.-S.1    Tak, M.-H.2    Lee, M.-H.3
  • 23
    • 33751229313 scopus 로고    scopus 로고
    • Phospholipase Cbeta 3 mediates the scratching response activated by the histamine H1 receptor on C-fiber nociceptive neurons
    • COI: 1:CAS:528:DC%2BD28XhtlSmtLnE, PID: 17114052
    • Han S-K, Mancino V, Simon MI (2006) Phospholipase Cbeta 3 mediates the scratching response activated by the histamine H1 receptor on C-fiber nociceptive neurons. Neuron 52:691–703
    • (2006) Neuron , vol.52 , pp. 691-703
    • Han, S.-K.1    Mancino, V.2    Simon, M.I.3
  • 24
    • 0037066069 scopus 로고    scopus 로고
    • Characterisation of the calcium responses to histamine in capsaicin-sensitive and capsaicin-insensitive sensory neurones
    • COI: 1:CAS:528:DC%2BD38XhslSrsr8%3D, PID: 11958874
    • Nicolson TA, Bevan S, Richards CD (2002) Characterisation of the calcium responses to histamine in capsaicin-sensitive and capsaicin-insensitive sensory neurones. Neuroscience 110:329–338
    • (2002) Neuroscience , vol.110 , pp. 329-338
    • Nicolson, T.A.1    Bevan, S.2    Richards, C.D.3
  • 25
    • 2942530381 scopus 로고    scopus 로고
    • Involvement of histamine H4 and H1 receptors in scratching induced by histamine receptor agonists in Balb C mice
    • COI: 1:CAS:528:DC%2BD2cXkvVyksLs%3D, PID: 15066908
    • Bell JK, McQueen DS, Rees JL (2004) Involvement of histamine H4 and H1 receptors in scratching induced by histamine receptor agonists in Balb C mice. Br J Pharmacol 142:374–380
    • (2004) Br J Pharmacol , vol.142 , pp. 374-380
    • Bell, J.K.1    McQueen, D.S.2    Rees, J.L.3
  • 26
    • 33845924770 scopus 로고    scopus 로고
    • Histamine H4 receptor antagonists are superior to traditional antihistamines in the attenuation of experimental pruritus
    • COI: 1:CAS:528:DC%2BD2sXit1OktQ%3D%3D, PID: 17208599
    • Dunford PJ, Williams KN, Desai PJ et al (2007) Histamine H4 receptor antagonists are superior to traditional antihistamines in the attenuation of experimental pruritus. J Allergy Clin Immunol 119:176–183
    • (2007) J Allergy Clin Immunol , vol.119 , pp. 176-183
    • Dunford, P.J.1    Williams, K.N.2    Desai, P.J.3
  • 27
    • 0032161858 scopus 로고    scopus 로고
    • Substance P induction of itch-associated response mediated by cutaneous NK1 tachykinin receptors in mice
    • COI: 1:CAS:528:DyaK1cXmt1Grurc%3D, PID: 9732370
    • Andoh T, Nagasawa T, Satoh M, Kuraishi Y (1998) Substance P induction of itch-associated response mediated by cutaneous NK1 tachykinin receptors in mice. J Pharmacol Exp Ther 286:1140–1145
    • (1998) J Pharmacol Exp Ther , vol.286 , pp. 1140-1145
    • Andoh, T.1    Nagasawa, T.2    Satoh, M.3    Kuraishi, Y.4
  • 28
    • 0018253625 scopus 로고
    • Flare and itch induced by substance P in human skin
    • PID: 81243
    • Hägermark O, Hökfelt T, Pernow B (1978) Flare and itch induced by substance P in human skin. J Invest Dermatol 71:233–235
    • (1978) J Invest Dermatol , vol.71 , pp. 233-235
    • Hägermark, O.1    Hökfelt, T.2    Pernow, B.3
  • 29
    • 0011892840 scopus 로고
    • Proteolytic activity in development of pain and itching. Cutaneous reactions to bradykinin and kallikrein
    • COI: 1:CAS:528:DyaF3MXhtFems78%3D, PID: 13811988
    • CORMIA FE, DOUGHERTY JW (1960) Proteolytic activity in development of pain and itching. Cutaneous reactions to bradykinin and kallikrein. J Invest Dermatol 35:21–26
    • (1960) J Invest Dermatol , vol.35 , pp. 21-26
    • CORMIA, F.E.1    DOUGHERTY, J.W.2
  • 30
    • 0016261283 scopus 로고
    • Studies on experimental itch induced by kallikrein and bradykinin
    • PID: 4138516
    • Hägermark O (1974) Studies on experimental itch induced by kallikrein and bradykinin. Acta Derm Venereol 54:397–400
    • (1974) Acta Derm Venereol , vol.54 , pp. 397-400
    • Hägermark, O.1
  • 31
    • 33751016799 scopus 로고    scopus 로고
    • Bradykinin is a potent pruritogen in atopic dermatitis: a switch from pain to itch
    • COI: 1:CAS:528:DC%2BD28Xht1agtrbF, PID: 16842920
    • Hosogi M, Schmelz M, Miyachi Y, Ikoma A (2006) Bradykinin is a potent pruritogen in atopic dermatitis: a switch from pain to itch. Pain 126:16–23
    • (2006) Pain , vol.126 , pp. 16-23
    • Hosogi, M.1    Schmelz, M.2    Miyachi, Y.3    Ikoma, A.4
  • 32
    • 1842475312 scopus 로고    scopus 로고
    • Noxious cold ion channel TRPA1 is activated by pungent compounds and bradykinin
    • COI: 1:CAS:528:DC%2BD2cXjtValtL8%3D, PID: 15046718
    • Bandell M, Story GM, Hwang SW et al (2004) Noxious cold ion channel TRPA1 is activated by pungent compounds and bradykinin. Neuron 41:849–857
    • (2004) Neuron , vol.41 , pp. 849-857
    • Bandell, M.1    Story, G.M.2    Hwang, S.W.3
  • 33
    • 44949182742 scopus 로고    scopus 로고
    • Phospholipase C and protein kinase A mediate bradykinin sensitization of TRPA1: a molecular mechanism of inflammatory pain
    • PID: 18356188
    • Wang S, Dai Y, Fukuoka T et al (2008) Phospholipase C and protein kinase A mediate bradykinin sensitization of TRPA1: a molecular mechanism of inflammatory pain. Brain 131:1241–1251
    • (2008) Brain , vol.131 , pp. 1241-1251
    • Wang, S.1    Dai, Y.2    Fukuoka, T.3
  • 34
    • 33646045075 scopus 로고    scopus 로고
    • TRPA1 mediates the inflammatory actions of environmental irritants and proalgesic agents
    • COI: 1:CAS:528:DC%2BD28Xjt1Khs70%3D, PID: 16564016
    • Bautista DM, Jordt S-E, Nikai T et al (2006) TRPA1 mediates the inflammatory actions of environmental irritants and proalgesic agents. Cell 124:1269–1282
    • (2006) Cell , vol.124 , pp. 1269-1282
    • Bautista, D.M.1    Jordt, S.-E.2    Nikai, T.3
  • 35
    • 0035678082 scopus 로고    scopus 로고
    • Involvement of leukotriene B(4) in substance P-induced itch-associated response in mice
    • COI: 1:CAS:528:DC%2BD38XjtValsA%3D%3D, PID: 11886531
    • Andoh T, Katsube N, Maruyama M, Kuraishi Y (2001) Involvement of leukotriene B(4) in substance P-induced itch-associated response in mice. J Invest Dermatol 117:1621–1626
    • (2001) J Invest Dermatol , vol.117 , pp. 1621-1626
    • Andoh, T.1    Katsube, N.2    Maruyama, M.3    Kuraishi, Y.4
  • 36
    • 0037276535 scopus 로고    scopus 로고
    • Nitric oxide enhances substance P-induced itch-associated responses in mice
    • COI: 1:CAS:528:DC%2BD3sXhtF2hs78%3D, PID: 12522091
    • Andoh T, Kuraishi Y (2003) Nitric oxide enhances substance P-induced itch-associated responses in mice. Br J Pharmacol 138:202–208
    • (2003) Br J Pharmacol , vol.138 , pp. 202-208
    • Andoh, T.1    Kuraishi, Y.2
  • 37
    • 0026647484 scopus 로고
    • Activation of capsaicin-sensitive primary afferents in the rat urinary bladder by compound 48/80: a direct action on sensory nerves?
    • COI: 1:CAS:528:DyaK38Xks1Ont7Y%3D, PID: 1417367
    • Eglezos A, Lecci A, Santicioli P et al (1992) Activation of capsaicin-sensitive primary afferents in the rat urinary bladder by compound 48/80: a direct action on sensory nerves? Arch Int Pharmacodyn Thér 315:96–109
    • (1992) Arch Int Pharmacodyn Thér , vol.315 , pp. 96-109
    • Eglezos, A.1    Lecci, A.2    Santicioli, P.3
  • 38
    • 0035822998 scopus 로고    scopus 로고
    • A diverse family of GPCRs expressed in specific subsets of nociceptive sensory neurons
    • COI: 1:CAS:528:DC%2BD3MXmvF2mu74%3D, PID: 11551509
    • Dong X, Han S, Zylka MJ et al (2001) A diverse family of GPCRs expressed in specific subsets of nociceptive sensory neurons. Cell 106:619–632
    • (2001) Cell , vol.106 , pp. 619-632
    • Dong, X.1    Han, S.2    Zylka, M.J.3
  • 39
    • 84927947337 scopus 로고    scopus 로고
    • The role of the Mrgpr receptor family in itch
    • PID: 25861775
    • Liu Q, Dong X (2015) The role of the Mrgpr receptor family in itch. Handb Exp Pharmacol 226:71–88
    • (2015) Handb Exp Pharmacol , vol.226 , pp. 71-88
    • Liu, Q.1    Dong, X.2
  • 40
    • 79956321743 scopus 로고    scopus 로고
    • BAM8-22 peptide produces itch and nociceptive sensations in humans independent of histamine release
    • COI: 1:CAS:528:DC%2BC3MXmvFektbk%3D, PID: 21593341
    • Sikand P, Dong X, LaMotte RH (2011) BAM8-22 peptide produces itch and nociceptive sensations in humans independent of histamine release. J Neurosci 31:7563–7567
    • (2011) J Neurosci , vol.31 , pp. 7563-7567
    • Sikand, P.1    Dong, X.2    LaMotte, R.H.3
  • 41
    • 84873088904 scopus 로고    scopus 로고
    • A subpopulation of nociceptors specifically linked to itch
    • COI: 1:CAS:528:DC%2BC38XhvVOrurjE, PID: 23263443
    • Han L, Ma C, Liu Q et al (2013) A subpopulation of nociceptors specifically linked to itch. Nat Neurosci 16:174–182
    • (2013) Nat Neurosci , vol.16 , pp. 174-182
    • Han, L.1    Ma, C.2    Liu, Q.3
  • 42
    • 84867605840 scopus 로고    scopus 로고
    • Mechanisms of itch evoked by β-alanine
    • COI: 1:CAS:528:DC%2BC38XhsFKrsrnO, PID: 23077038
    • Liu Q, Sikand P, Ma C et al (2012) Mechanisms of itch evoked by β-alanine. J Neurosci 32:14532–14537
    • (2012) J Neurosci , vol.32 , pp. 14532-14537
    • Liu, Q.1    Sikand, P.2    Ma, C.3
  • 43
    • 0030709263 scopus 로고    scopus 로고
    • Can a serotonin type 3 (5-HT3) receptor antagonist reduce experimentally-induced itch?
    • COI: 1:CAS:528:DyaK1cXms1entg%3D%3D, PID: 9372314
    • Weisshaar E, Ziethen B, Gollnick H (1997) Can a serotonin type 3 (5-HT3) receptor antagonist reduce experimentally-induced itch? Inflamm Res 46:412–416
    • (1997) Inflamm Res , vol.46 , pp. 412-416
    • Weisshaar, E.1    Ziethen, B.2    Gollnick, H.3
  • 44
    • 33748943679 scopus 로고    scopus 로고
    • Neuronal 5-HT metabotropic receptors: fine-tuning of their structure, signaling, and roles in synaptic modulation
    • COI: 1:CAS:528:DC%2BD28XpvFaltLs%3D, PID: 16896947
    • Bockaert J, Claeysen S, Bécamel C et al (2006) Neuronal 5-HT metabotropic receptors: fine-tuning of their structure, signaling, and roles in synaptic modulation. Cell Tissue Res 326:553–572
    • (2006) Cell Tissue Res , vol.326 , pp. 553-572
    • Bockaert, J.1    Claeysen, S.2    Bécamel, C.3
  • 45
    • 0032703315 scopus 로고    scopus 로고
    • Itch-associated response induced by intradermal serotonin through 5-HT2 receptors in mice
    • COI: 1:CAS:528:DyaK1MXntVChtrg%3D, PID: 10616911
    • Yamaguchi T, Nagasawa T, Satoh M, Kuraishi Y (1999) Itch-associated response induced by intradermal serotonin through 5-HT2 receptors in mice. Neurosci Res 35:77–83
    • (1999) Neurosci Res , vol.35 , pp. 77-83
    • Yamaguchi, T.1    Nagasawa, T.2    Satoh, M.3    Kuraishi, Y.4
  • 46
    • 84937516283 scopus 로고    scopus 로고
    • HTR7 mediates serotonergic acute and chronic itch
    • COI: 1:CAS:528:DC%2BC2MXhtVeiu77L, PID: 26074006
    • Morita T, McClain SP, Batia LM et al (2015) HTR7 mediates serotonergic acute and chronic itch. Neuron 87:124–138
    • (2015) Neuron , vol.87 , pp. 124-138
    • Morita, T.1    McClain, S.P.2    Batia, L.M.3
  • 47
    • 84875704973 scopus 로고    scopus 로고
    • 4-induced itch by transient receptor potential ankyrin 1 and transient receptor potential vanilloid 1
    • COI: 1:CAS:528:DC%2BC3sXmtFegtLc%3D, PID: 23271050
    • 4-induced itch by transient receptor potential ankyrin 1 and transient receptor potential vanilloid 1. FASEB J 27:1664–1673
    • (2013) FASEB J , vol.27 , pp. 1664-1673
    • Fernandes, E.S.1    Vong, C.T.2    Quek, S.3
  • 48
    • 0022598215 scopus 로고
    • Skin levels of arachidonic acid-derived inflammatory mediators and histamine in atopic dermatitis and psoriasis
    • COI: 1:STN:280:DyaL28zgsF2msg%3D%3D, PID: 3018086
    • Ruzicka T, Simmet T, Peskar BA, Ring J (1986) Skin levels of arachidonic acid-derived inflammatory mediators and histamine in atopic dermatitis and psoriasis. J Invest Dermatol 86:105–108
    • (1986) J Invest Dermatol , vol.86 , pp. 105-108
    • Ruzicka, T.1    Simmet, T.2    Peskar, B.A.3    Ring, J.4
  • 49
    • 0035206419 scopus 로고    scopus 로고
    • Clinical and biochemical effects of zileuton in patients with the Sjögren-Larsson syndrome
    • COI: 1:CAS:528:DC%2BD3MXosFGgurg%3D, PID: 11795678
    • Willemsen MA, Lutt MA, Steijlen PM et al (2001) Clinical and biochemical effects of zileuton in patients with the Sjögren-Larsson syndrome. Eur J Pediatr 160:711–717
    • (2001) Eur J Pediatr , vol.160 , pp. 711-717
    • Willemsen, M.A.1    Lutt, M.A.2    Steijlen, P.M.3
  • 50
    • 0021287558 scopus 로고
    • The release of leukotriene B4-like material in biologically active amounts from the lesional skin of patients with psoriasis
    • COI: 1:CAS:528:DyaL2cXkvVygsbw%3D, PID: 6330213
    • Brain S, Camp R, Dowd P et al (1984) The release of leukotriene B4-like material in biologically active amounts from the lesional skin of patients with psoriasis. J Invest Dermatol 83:70–73
    • (1984) J Invest Dermatol , vol.83 , pp. 70-73
    • Brain, S.1    Camp, R.2    Dowd, P.3
  • 51
    • 79958126214 scopus 로고    scopus 로고
    • Leukotriene B(4) mediates sphingosylphosphorylcholine-induced itch-associated responses in mouse skin
    • COI: 1:CAS:528:DC%2BD1MXhtl2jsLvJ, PID: 19657356
    • Andoh T, Saito A, Kuraishi Y (2009) Leukotriene B(4) mediates sphingosylphosphorylcholine-induced itch-associated responses in mouse skin. J Invest Dermatol 129:2854–2860
    • (2009) J Invest Dermatol , vol.129 , pp. 2854-2860
    • Andoh, T.1    Saito, A.2    Kuraishi, Y.3
  • 52
    • 84860279973 scopus 로고    scopus 로고
    • Pruritus in chronic cholestatic liver disease
    • PID: 22541702
    • Bunchorntavakul C, Reddy KR (2012) Pruritus in chronic cholestatic liver disease. Clin Liver Dis 16:331–346
    • (2012) Clin Liver Dis , vol.16 , pp. 331-346
    • Bunchorntavakul, C.1    Reddy, K.R.2
  • 53
    • 0017691040 scopus 로고
    • Elevations in skin tissue levels of bile acids in human cholestasis: relation to serum levels and topruritus
    • COI: 1:STN:280:DyaE1c%2FgsVejsw%3D%3D, PID: 908491
    • Ghent CN, Bloomer JR, Klatskin G (1977) Elevations in skin tissue levels of bile acids in human cholestasis: relation to serum levels and topruritus. Gastroenterology 73:1125–1130
    • (1977) Gastroenterology , vol.73 , pp. 1125-1130
    • Ghent, C.N.1    Bloomer, J.R.2    Klatskin, G.3
  • 54
    • 0016064821 scopus 로고
    • Pruritus induced by crude bile and purified bile acids. Experimental production of pruritus in human skin
    • COI: 1:STN:280:DyaE2c7msVeitQ%3D%3D, PID: 4828535
    • Varadi DP (1974) Pruritus induced by crude bile and purified bile acids. Experimental production of pruritus in human skin. Arch Dermatol 109:678–681
    • (1974) Arch Dermatol , vol.109 , pp. 678-681
    • Varadi, D.P.1
  • 55
    • 0037392389 scopus 로고    scopus 로고
    • Review article: pruritus in cholestatic and other liver diseases
    • COI: 1:CAS:528:DC%2BD3sXjslSrsL4%3D, PID: 12656688
    • Mela M, Mancuso A, Burroughs AK (2003) Review article: pruritus in cholestatic and other liver diseases. Aliment Pharmacol Ther 17:857–870
    • (2003) Aliment Pharmacol Ther , vol.17 , pp. 857-870
    • Mela, M.1    Mancuso, A.2    Burroughs, A.K.3
  • 56
    • 84875848761 scopus 로고    scopus 로고
    • The TGR5 receptor mediates bile acid-induced itch and analgesia
    • COI: 1:CAS:528:DC%2BC3sXlvVKhsL8%3D, PID: 23524965
    • Alemi F, Kwon E, Poole DP et al (2013) The TGR5 receptor mediates bile acid-induced itch and analgesia. J Clin Invest 123:1513–1530
    • (2013) J Clin Invest , vol.123 , pp. 1513-1530
    • Alemi, F.1    Kwon, E.2    Poole, D.P.3
  • 57
    • 84913533041 scopus 로고    scopus 로고
    • The bile acid receptor TGR5 activates the TRPA1 channel to induce itch in mice
    • COI: 1:CAS:528:DC%2BC2cXhvFOgsrzO, PID: 25194674
    • Lieu T, Jayaweera G, Zhao P et al (2014) The bile acid receptor TGR5 activates the TRPA1 channel to induce itch in mice. Gastroenterology 147:1417–1428
    • (2014) Gastroenterology , vol.147 , pp. 1417-1428
    • Lieu, T.1    Jayaweera, G.2    Zhao, P.3
  • 58
    • 4043072745 scopus 로고    scopus 로고
    • Itch-scratch responses induced by lysophosphatidic acid in mice
    • COI: 1:CAS:528:DC%2BD2cXmsV2itbg%3D, PID: 15292655
    • Hashimoto T, Ohata H, Momose K (2004) Itch-scratch responses induced by lysophosphatidic acid in mice. Pharmacology 72:51–56
    • (2004) Pharmacology , vol.72 , pp. 51-56
    • Hashimoto, T.1    Ohata, H.2    Momose, K.3
  • 59
    • 84925581702 scopus 로고    scopus 로고
    • Lysophosphatidic acid is a potential mediator of cholestatic pruritus
    • COI: 1:CAS:528:DC%2BC3cXhtV2iurrI, PID: 20546739, 1018.e1
    • Kremer AE, Martens JJ, Kulik W et al (2010) Lysophosphatidic acid is a potential mediator of cholestatic pruritus. Gastroenterology 139:1008–1018, 1018.e1
    • (2010) Gastroenterology , vol.139 , pp. 1008-1018
    • Kremer, A.E.1    Martens, J.J.2    Kulik, W.3
  • 60
    • 84899540615 scopus 로고    scopus 로고
    • Potentials of the circulating pruritogenic mediator lysophosphatidic acid in development of allergic skin inflammation in mice: role of blood cell-associated lysophospholipase D activity of autotaxin
    • COI: 1:CAS:528:DC%2BC2cXnsVemtbk%3D, PID: 24641902
    • Shimizu Y, Morikawa Y, Okudaira S et al (2014) Potentials of the circulating pruritogenic mediator lysophosphatidic acid in development of allergic skin inflammation in mice: role of blood cell-associated lysophospholipase D activity of autotaxin. Am J Pathol 184:1593–1603
    • (2014) Am J Pathol , vol.184 , pp. 1593-1603
    • Shimizu, Y.1    Morikawa, Y.2    Okudaira, S.3
  • 61
    • 83655161366 scopus 로고    scopus 로고
    • Lysophosphatidic acid directly activates TRPV1 through a C-terminal binding site
    • COI: 1:CAS:528:DC%2BC3MXhsV2gt7zL
    • Nieto-Posadas A, Picazo-Juárez G, Llorente I et al (2012) Lysophosphatidic acid directly activates TRPV1 through a C-terminal binding site. Nat Chem Biol 8:78–85
    • (2012) Nat Chem Biol , vol.8 , pp. 78-85
    • Nieto-Posadas, A.1    Picazo-Juárez, G.2    Llorente, I.3
  • 62
    • 0033670389 scopus 로고    scopus 로고
    • The neurogenic vasodilator response to endothelin-1: a study in human skin in vivo
    • COI: 1:CAS:528:DC%2BD3MXktlSqug%3D%3D, PID: 11187978
    • Katugampola R, Church MK, Clough GF (2000) The neurogenic vasodilator response to endothelin-1: a study in human skin in vivo. Exp Physiol 85:839–846
    • (2000) Exp Physiol , vol.85 , pp. 839-846
    • Katugampola, R.1    Church, M.K.2    Clough, G.F.3
  • 63
    • 84902166170 scopus 로고    scopus 로고
    • Neural peptidase endothelin-converting enzyme 1 regulates endothelin 1-induced pruritus
    • COI: 1:CAS:528:DC%2BC2cXpvFahs74%3D, PID: 24812665
    • Kido-Nakahara M, Buddenkotte J, Kempkes C et al (2014) Neural peptidase endothelin-converting enzyme 1 regulates endothelin 1-induced pruritus. J Clin Invest 124:2683–2695
    • (2014) J Clin Invest , vol.124 , pp. 2683-2695
    • Kido-Nakahara, M.1    Buddenkotte, J.2    Kempkes, C.3
  • 65
    • 78049343477 scopus 로고    scopus 로고
    • Molecular signaling of pruritus induced by endothelin-1 in mice
    • COI: 1:CAS:528:DC%2BC3cXhsFahsLzF
    • Liang J, Kawamata T, Ji W (2010) Molecular signaling of pruritus induced by endothelin-1 in mice. Exp Biol Med (Maywood) 235:1300–1305
    • (2010) Exp Biol Med (Maywood) , vol.235 , pp. 1300-1305
    • Liang, J.1    Kawamata, T.2    Ji, W.3
  • 66
    • 79952282096 scopus 로고    scopus 로고
    • Functional endothelin receptors are selectively expressed in isolectin B4-negative sensory neurons and are upregulated in isolectin B4-positive neurons by neurturin and glia-derived neurotropic factor
    • COI: 1:CAS:528:DC%2BC3MXjsFags7o%3D, PID: 21241671
    • Vellani V, Prandini M, Giacomoni C et al (2011) Functional endothelin receptors are selectively expressed in isolectin B4-negative sensory neurons and are upregulated in isolectin B4-positive neurons by neurturin and glia-derived neurotropic factor. Brain Res 1381:31–37
    • (2011) Brain Res , vol.1381 , pp. 31-37
    • Vellani, V.1    Prandini, M.2    Giacomoni, C.3
  • 67
    • 84861634949 scopus 로고    scopus 로고
    • Cathepsin E induces itch-related response through the production of endothelin-1 in mice
    • COI: 1:CAS:528:DC%2BC38XntFaisbg%3D, PID: 22546226
    • Andoh T, Yoshida T, Lee J-B, Kuraishi Y (2012) Cathepsin E induces itch-related response through the production of endothelin-1 in mice. Eur J Pharmacol 686:16–21
    • (2012) Eur J Pharmacol , vol.686 , pp. 16-21
    • Andoh, T.1    Yoshida, T.2    Lee, J.-B.3    Kuraishi, Y.4
  • 68
    • 0035019636 scopus 로고    scopus 로고
    • Proteinase-activated receptors
    • COI: 1:CAS:528:DC%2BD3MXkt1GnurY%3D, PID: 11356985
    • Macfarlane SR, Seatter MJ, Kanke T et al (2001) Proteinase-activated receptors. Pharmacol Rev 53:245–282
    • (2001) Pharmacol Rev , vol.53 , pp. 245-282
    • Macfarlane, S.R.1    Seatter, M.J.2    Kanke, T.3
  • 69
    • 43749117724 scopus 로고    scopus 로고
    • Cowhage-evoked itch is mediated by a novel cysteine protease: a ligand of protease-activated receptors
    • COI: 1:CAS:528:DC%2BD1cXlsVWgsrg%3D, PID: 18434511
    • Reddy VB, Iuga AO, Shimada SG et al (2008) Cowhage-evoked itch is mediated by a novel cysteine protease: a ligand of protease-activated receptors. J Neurosci 28:4331–4335
    • (2008) J Neurosci , vol.28 , pp. 4331-4335
    • Reddy, V.B.1    Iuga, A.O.2    Shimada, S.G.3
  • 70
    • 0033971235 scopus 로고    scopus 로고
    • Agonists of proteinase-activated receptor 2 induce inflammation by a neurogenic mechanism
    • COI: 1:CAS:528:DC%2BD3cXosFyqtw%3D%3D, PID: 10655102
    • Steinhoff M, Vergnolle N, Young SH et al (2000) Agonists of proteinase-activated receptor 2 induce inflammation by a neurogenic mechanism. Nat Med 6:151–158
    • (2000) Nat Med , vol.6 , pp. 151-158
    • Steinhoff, M.1    Vergnolle, N.2    Young, S.H.3
  • 71
    • 77951093867 scopus 로고    scopus 로고
    • Cathepsin S elicits itch and signals via protease-activated receptors
    • COI: 1:CAS:528:DC%2BC3cXkvVSrtbw%3D, PID: 20072136
    • Reddy VB, Shimada SG, Sikand P et al (2010) Cathepsin S elicits itch and signals via protease-activated receptors. J Invest Dermatol 130:1468–1470
    • (2010) J Invest Dermatol , vol.130 , pp. 1468-1470
    • Reddy, V.B.1    Shimada, S.G.2    Sikand, P.3
  • 72
    • 0032814121 scopus 로고    scopus 로고
    • Proteinase-activated receptor-2 in human skin: tissue distribution and activation of keratinocytes by mast cell tryptase
    • COI: 1:CAS:528:DyaK1MXltlOnu7w%3D, PID: 10439226
    • Steinhoff M, Corvera CU, Thoma MS et al (1999) Proteinase-activated receptor-2 in human skin: tissue distribution and activation of keratinocytes by mast cell tryptase. Exp Dermatol 8:282–294
    • (1999) Exp Dermatol , vol.8 , pp. 282-294
    • Steinhoff, M.1    Corvera, C.U.2    Thoma, M.S.3
  • 73
    • 0038720558 scopus 로고    scopus 로고
    • Proteinase-activated receptor-2 mediates itch: a novel pathway for pruritus in human skin
    • COI: 1:CAS:528:DC%2BD3sXlvVCgsr0%3D, PID: 12867500
    • Steinhoff M, Neisius U, Ikoma A et al (2003) Proteinase-activated receptor-2 mediates itch: a novel pathway for pruritus in human skin. J Neurosci 23:6176–6180
    • (2003) J Neurosci , vol.23 , pp. 6176-6180
    • Steinhoff, M.1    Neisius, U.2    Ikoma, A.3
  • 74
    • 67249103872 scopus 로고    scopus 로고
    • Involvement of tryptase and proteinase-activated receptor-2 in spontaneous itch-associated response in mice with atopy-like dermatitis
    • COI: 1:CAS:528:DC%2BD1MXktVSqu70%3D, PID: 19270428
    • Tsujii K, Andoh T, Ui H et al (2009) Involvement of tryptase and proteinase-activated receptor-2 in spontaneous itch-associated response in mice with atopy-like dermatitis. J Pharmacol Sci 109:388–395
    • (2009) J Pharmacol Sci , vol.109 , pp. 388-395
    • Tsujii, K.1    Andoh, T.2    Ui, H.3
  • 75
    • 84858182949 scopus 로고    scopus 로고
    • Overexpression of cathepsin S induces chronic atopic dermatitis in mice
    • COI: 1:CAS:528:DC%2BC3MXhs1aitrnK, PID: 22170489
    • Kim N, Bae KB, Kim MO et al (2012) Overexpression of cathepsin S induces chronic atopic dermatitis in mice. J Invest Dermatol 132:1169–1176
    • (2012) J Invest Dermatol , vol.132 , pp. 1169-1176
    • Kim, N.1    Bae, K.B.2    Kim, M.O.3
  • 76
    • 30444454009 scopus 로고    scopus 로고
    • Scratching behavior in mice induced by the proteinase-activated receptor-2 agonist, SLIGRL-NH2
    • COI: 1:CAS:528:DC%2BD28XjvVCmsQ%3D%3D, PID: 16356490
    • Shimada SG, Shimada KA, Collins JG (2006) Scratching behavior in mice induced by the proteinase-activated receptor-2 agonist, SLIGRL-NH2. Eur J Pharmacol 530:281–283
    • (2006) Eur J Pharmacol , vol.530 , pp. 281-283
    • Shimada, S.G.1    Shimada, K.A.2    Collins, J.G.3
  • 77
    • 79960365417 scopus 로고    scopus 로고
    • The distinct roles of two GPCRs, MrgprC11 and PAR2, in itch and hyperalgesia
    • COI: 1:CAS:528:DC%2BC3MXhtFOis7bN, PID: 21775281
    • Liu Q, Weng H-J, Patel KN et al (2011) The distinct roles of two GPCRs, MrgprC11 and PAR2, in itch and hyperalgesia. Sci Signal 4:ra45
    • (2011) Sci Signal , vol.4 , pp. ra45
    • Liu, Q.1    Weng, H.-J.2    Patel, K.N.3
  • 78
    • 84938151125 scopus 로고    scopus 로고
    • Redefining the concept of protease-activated receptors: cathepsin S evokes itch via activation of Mrgprs
    • COI: 1:CAS:528:DC%2BC2MXhtlCjtr3P, PID: 26216096
    • Reddy VB, Sun S, Azimi E et al (2015) Redefining the concept of protease-activated receptors: cathepsin S evokes itch via activation of Mrgprs. Nat Commun 6:7864
    • (2015) Nat Commun , vol.6 , pp. 7864
    • Reddy, V.B.1    Sun, S.2    Azimi, E.3
  • 79
    • 84885674640 scopus 로고    scopus 로고
    • The epithelial cell-derived atopic dermatitis cytokine TSLP activates neurons to induce itch
    • COI: 1:CAS:528:DC%2BC3sXhsFOlsb%2FE, PID: 24094650
    • Wilson SR, Thé L, Batia LM et al (2013) The epithelial cell-derived atopic dermatitis cytokine TSLP activates neurons to induce itch. Cell 155:285–295
    • (2013) Cell , vol.155 , pp. 285-295
    • Wilson, S.R.1    Thé, L.2    Batia, L.M.3
  • 80
    • 2342604388 scopus 로고    scopus 로고
    • Protease-activated receptor 2 sensitizes the capsaicin receptor transient receptor potential vanilloid receptor 1 to induce hyperalgesia
    • COI: 1:CAS:528:DC%2BD2cXktFCjt7g%3D, PID: 15128844
    • Amadesi S, Nie J, Vergnolle N et al (2004) Protease-activated receptor 2 sensitizes the capsaicin receptor transient receptor potential vanilloid receptor 1 to induce hyperalgesia. J Neurosci 24:4300–4312
    • (2004) J Neurosci , vol.24 , pp. 4300-4312
    • Amadesi, S.1    Nie, J.2    Vergnolle, N.3
  • 81
    • 34447121851 scopus 로고    scopus 로고
    • Sensitization of TRPA1 by PAR2 contributes to the sensation of inflammatory pain
    • COI: 1:CAS:528:DC%2BD2sXhtFCnt7nM
    • Dai Y, Wang S, Tominaga M et al (2007) Sensitization of TRPA1 by PAR2 contributes to the sensation of inflammatory pain. J Clin Invest 117:3140–3140
    • (2007) J Clin Invest , vol.117 , pp. 3140
    • Dai, Y.1    Wang, S.2    Tominaga, M.3
  • 82
    • 33846903838 scopus 로고    scopus 로고
    • Cytokine receptor signaling through the Jak-Stat-Socs pathway in disease
    • PID: 17208301
    • O’Sullivan LA, Liongue C, Lewis RS et al (2007) Cytokine receptor signaling through the Jak-Stat-Socs pathway in disease. Mol Immunol 44:2497–2506
    • (2007) Mol Immunol , vol.44 , pp. 2497-2506
    • O’Sullivan, L.A.1    Liongue, C.2    Lewis, R.S.3
  • 83
    • 84874544507 scopus 로고    scopus 로고
    • The biology of thymic stromal lymphopoietin (TSLP)
    • COI: 1:CAS:528:DC%2BC3sXhtVWgs7zF, PID: 23433457
    • Ziegler SF, Roan F, Bell BD et al (2013) The biology of thymic stromal lymphopoietin (TSLP). Adv Pharmacol 66:129–155
    • (2013) Adv Pharmacol , vol.66 , pp. 129-155
    • Ziegler, S.F.1    Roan, F.2    Bell, B.D.3
  • 84
    • 23944459169 scopus 로고    scopus 로고
    • Spontaneous atopic dermatitis in mice expressing an inducible thymic stromal lymphopoietin transgene specifically in the skin
    • COI: 1:CAS:528:DC%2BD2MXosVarsrk%3D, PID: 16103410
    • Yoo J, Omori M, Gyarmati D et al (2005) Spontaneous atopic dermatitis in mice expressing an inducible thymic stromal lymphopoietin transgene specifically in the skin. J Exp Med 202:541–549
    • (2005) J Exp Med , vol.202 , pp. 541-549
    • Yoo, J.1    Omori, M.2    Gyarmati, D.3
  • 85
    • 75749149721 scopus 로고    scopus 로고
    • Thymic stromal lymphopoietin
    • COI: 1:CAS:528:DC%2BC3cXisVehsrg%3D, PID: 20146705
    • He R, Geha RS (2010) Thymic stromal lymphopoietin. Ann N Y Acad Sci 1183:13–24
    • (2010) Ann N Y Acad Sci , vol.1183 , pp. 13-24
    • He, R.1    Geha, R.S.2
  • 86
    • 84887825524 scopus 로고    scopus 로고
    • IL-31 is produced by the malignant T-cell population in cutaneous T-cell lymphoma and correlates with CTCL pruritus
    • COI: 1:CAS:528:DC%2BC3sXhtVWgt7nO, PID: 23698099
    • Singer EM, Shin DB, Nattkemper LA et al (2013) IL-31 is produced by the malignant T-cell population in cutaneous T-cell lymphoma and correlates with CTCL pruritus. J Invest Dermatol 133:2783–2785
    • (2013) J Invest Dermatol , vol.133 , pp. 2783-2785
    • Singer, E.M.1    Shin, D.B.2    Nattkemper, L.A.3
  • 87
    • 79959349600 scopus 로고    scopus 로고
    • Atopic dermatitis: a disease of altered skin barrier and immune dysregulation
    • COI: 1:CAS:528:DC%2BC3MXot1OntLg%3D, PID: 21682749
    • Boguniewicz M, Leung DYM (2011) Atopic dermatitis: a disease of altered skin barrier and immune dysregulation. Immunol Rev 242:233–246
    • (2011) Immunol Rev , vol.242 , pp. 233-246
    • Boguniewicz, M.1    Leung, D.Y.M.2
  • 88
    • 57649243697 scopus 로고    scopus 로고
    • Anti-interleukin-31-antibodies ameliorate scratching behaviour in NC/Nga mice: a model of atopic dermatitis
    • COI: 1:CAS:528:DC%2BD1MXhslyrsrY%3D, PID: 19054054
    • Grimstad O, Sawanobori Y, Vestergaard C et al (2009) Anti-interleukin-31-antibodies ameliorate scratching behaviour in NC/Nga mice: a model of atopic dermatitis. Exp Dermatol 18:35–43
    • (2009) Exp Dermatol , vol.18 , pp. 35-43
    • Grimstad, O.1    Sawanobori, Y.2    Vestergaard, C.3
  • 89
    • 3242798310 scopus 로고    scopus 로고
    • Interleukin 31, a cytokine produced by activated T cells, induces dermatitis in mice
    • COI: 1:CAS:528:DC%2BD2cXlt1WmurY%3D, PID: 15184896
    • Dillon SR, Sprecher C, Hammond A et al (2004) Interleukin 31, a cytokine produced by activated T cells, induces dermatitis in mice. Nat Immunol 5:752–760
    • (2004) Nat Immunol , vol.5 , pp. 752-760
    • Dillon, S.R.1    Sprecher, C.2    Hammond, A.3
  • 90
    • 84895065194 scopus 로고    scopus 로고
    • A sensory neuron-expressed IL-31 receptor mediates T helper cell-dependent itch: involvement of TRPV1 and TRPA1
    • COI: 1:CAS:528:DC%2BC3sXitVWjt73E, PID: 24373353
    • Cevikbas F, Wang X, Akiyama T et al (2014) A sensory neuron-expressed IL-31 receptor mediates T helper cell-dependent itch: involvement of TRPV1 and TRPA1. J Allergy Clin Immunol 133:448–460
    • (2014) J Allergy Clin Immunol , vol.133 , pp. 448-460
    • Cevikbas, F.1    Wang, X.2    Akiyama, T.3
  • 91
    • 84888314492 scopus 로고    scopus 로고
    • TRPA1-dependent pruritus in IL-13-induced chronic atopic dermatitis
    • COI: 1:CAS:528:DC%2BC3sXhslymsLbE, PID: 24140646
    • Oh M-H, Oh SY, Lu J et al (2013) TRPA1-dependent pruritus in IL-13-induced chronic atopic dermatitis. J Immunol 191:5371–5382
    • (2013) J Immunol , vol.191 , pp. 5371-5382
    • Oh, M.-H.1    Oh, S.Y.2    Lu, J.3
  • 92
    • 12444341944 scopus 로고    scopus 로고
    • Toll-like receptors in innate immunity
    • COI: 1:CAS:528:DC%2BD2cXhtVKru77P, PID: 15585605
    • Takeda K, Akira S (2005) Toll-like receptors in innate immunity. Int Immunol 17:1–14
    • (2005) Int Immunol , vol.17 , pp. 1-14
    • Takeda, K.1    Akira, S.2
  • 93
    • 70449730854 scopus 로고    scopus 로고
    • Toll-like receptors 3, 4, and 7 are expressed in the enteric nervous system and dorsal root ganglia
    • COI: 1:CAS:528:DC%2BD1MXhtl2it7bO, PID: 19546475
    • Barajon I, Serrao G, Arnaboldi F et al (2009) Toll-like receptors 3, 4, and 7 are expressed in the enteric nervous system and dorsal root ganglia. J Histochem Cytochem 57:1013–1023
    • (2009) J Histochem Cytochem , vol.57 , pp. 1013-1023
    • Barajon, I.1    Serrao, G.2    Arnaboldi, F.3
  • 94
    • 0036008014 scopus 로고    scopus 로고
    • Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway
    • COI: 1:CAS:528:DC%2BD38XhtVygurc%3D, PID: 11812998
    • Hemmi H, Kaisho T, Takeuchi O et al (2002) Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway. Nat Immunol 3:196–200
    • (2002) Nat Immunol , vol.3 , pp. 196-200
    • Hemmi, H.1    Kaisho, T.2    Takeuchi, O.3
  • 95
    • 84875173644 scopus 로고    scopus 로고
    • Therapy of human papillomavirus-related disease
    • COI: 1:CAS:528:DC%2BC38Xhsl2jur%2FM, PID: 23199967
    • Stern PL, van der Burg SH, Hampson IN et al (2012) Therapy of human papillomavirus-related disease. Vaccine 30(Suppl 5):F71–82
    • (2012) Vaccine , vol.30 , pp. F71-F82
    • Stern, P.L.1    van der Burg, S.H.2    Hampson, I.N.3
  • 96
    • 78650205054 scopus 로고    scopus 로고
    • Toll-like receptor 7 mediates pruritus
    • COI: 1:CAS:528:DC%2BC3cXhtlGrsL3I, PID: 21037581
    • Liu T, Xu Z-Z, Park C-K et al (2010) Toll-like receptor 7 mediates pruritus. Nat Neurosci 13:1460–1462
    • (2010) Nat Neurosci , vol.13 , pp. 1460-1462
    • Liu, T.1    Xu, Z.-Z.2    Park, C.-K.3
  • 97
    • 79952763777 scopus 로고    scopus 로고
    • Analysis of cellular and behavioral responses to imiquimod reveals a unique itch pathway in transient receptor potential vanilloid 1 (TRPV1)-expressing neurons
    • COI: 1:CAS:528:DC%2BC3MXislGgtbY%3D, PID: 21300878
    • Kim S-J, Park GH, Kim D et al (2011) Analysis of cellular and behavioral responses to imiquimod reveals a unique itch pathway in transient receptor potential vanilloid 1 (TRPV1)-expressing neurons. Proc Natl Acad Sci U S A 108:3371–3376
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 3371-3376
    • Kim, S.-J.1    Park, G.H.2    Kim, D.3
  • 98
    • 33745521238 scopus 로고    scopus 로고
    • The small antitumoral immune response modifier imiquimod interacts with adenosine receptor signaling in a TLR7- and TLR8-independent fashion
    • PID: 16575388
    • Schön MP, Schön M, Klotz K-N (2006) The small antitumoral immune response modifier imiquimod interacts with adenosine receptor signaling in a TLR7- and TLR8-independent fashion. J Invest Dermatol 126:1338–1347
    • (2006) J Invest Dermatol , vol.126 , pp. 1338-1347
    • Schön, M.P.1    Schön, M.2    Klotz, K.-N.3
  • 99
    • 84855586249 scopus 로고    scopus 로고
    • Imiquimod enhances excitability of dorsal root ganglion neurons by inhibiting background (K(2P)) and voltage-gated (K(v)1.1 and K(v)1.2) potassium channels
    • COI: 1:CAS:528:DC%2BC38XkvVOqu7Y%3D, PID: 22233604
    • Lee J, Kim T, Hong J et al (2012) Imiquimod enhances excitability of dorsal root ganglion neurons by inhibiting background (K(2P)) and voltage-gated (K(v)1.1 and K(v)1.2) potassium channels. Mol Pain 8:2
    • (2012) Mol Pain , vol.8 , pp. 2
    • Lee, J.1    Kim, T.2    Hong, J.3
  • 100
    • 84897467553 scopus 로고    scopus 로고
    • Extracellular microRNAs activate nociceptor neurons to elicit pain via TLR7 and TRPA1
    • COI: 1:CAS:528:DC%2BC2cXls1KjtLY%3D, PID: 24698267
    • Park C-K, Xu Z-Z, Berta T et al (2014) Extracellular microRNAs activate nociceptor neurons to elicit pain via TLR7 and TRPA1. Neuron 82:47–54
    • (2014) Neuron , vol.82 , pp. 47-54
    • Park, C.-K.1    Xu, Z.-Z.2    Berta, T.3
  • 101
    • 84906922249 scopus 로고    scopus 로고
    • TLR4 enhances histamine-mediated pruritus by potentiating TRPV1 activity
    • PID: 25139109
    • Min H, Lee H, Lim H et al (2014) TLR4 enhances histamine-mediated pruritus by potentiating TRPV1 activity. Mol Brain 7:59
    • (2014) Mol Brain , vol.7 , pp. 59
    • Min, H.1    Lee, H.2    Lim, H.3
  • 102
    • 84861794417 scopus 로고    scopus 로고
    • TLR3 deficiency impairs spinal cord synaptic transmission, central sensitization, and pruritus in mice
    • COI: 1:CAS:528:DC%2BC38XosFaqsr8%3D, PID: 22565312
    • Liu T, Berta T, Xu Z-Z et al (2012) TLR3 deficiency impairs spinal cord synaptic transmission, central sensitization, and pruritus in mice. J Clin Invest 122:2195–2207
    • (2012) J Clin Invest , vol.122 , pp. 2195-2207
    • Liu, T.1    Berta, T.2    Xu, Z.-Z.3
  • 103
    • 79956058346 scopus 로고    scopus 로고
    • LPS sensitizes TRPV1 via activation of TLR4 in trigeminal sensory neurons
    • COI: 1:CAS:528:DC%2BC3MXnvFSltrw%3D, PID: 21393555
    • Diogenes A, Ferraz CCR, Akopian AN et al (2011) LPS sensitizes TRPV1 via activation of TLR4 in trigeminal sensory neurons. J Dent Res 90:759–764
    • (2011) J Dent Res , vol.90 , pp. 759-764
    • Diogenes, A.1    Ferraz, C.C.R.2    Akopian, A.N.3
  • 104
    • 78650160059 scopus 로고    scopus 로고
    • Lipopolysaccharide from Porphyromonas gingivalis sensitizes capsaicin-sensitive nociceptors
    • PID: 21146075
    • Ferraz CCR, Henry MA, Hargreaves KM, Diogenes A (2011) Lipopolysaccharide from Porphyromonas gingivalis sensitizes capsaicin-sensitive nociceptors. J Endod 37:45–48
    • (2011) J Endod , vol.37 , pp. 45-48
    • Ferraz, C.C.R.1    Henry, M.A.2    Hargreaves, K.M.3    Diogenes, A.4
  • 105
    • 33751112220 scopus 로고    scopus 로고
    • Oxidative stress in the pathogenesis of skin disease
    • COI: 1:CAS:528:DC%2BD28Xht1Sgt7rF, PID: 17108903
    • Bickers DR, Athar M (2006) Oxidative stress in the pathogenesis of skin disease. J Invest Dermatol 126:2565–2575
    • (2006) J Invest Dermatol , vol.126 , pp. 2565-2575
    • Bickers, D.R.1    Athar, M.2
  • 106
    • 84873638826 scopus 로고    scopus 로고
    • TRPA1: a gatekeeper for inflammation
    • COI: 1:CAS:528:DC%2BC3sXjvFOnsbY%3D, PID: 23020579
    • Bautista DM, Pellegrino M, Tsunozaki M (2013) TRPA1: a gatekeeper for inflammation. Annu Rev Physiol 75:181–200
    • (2013) Annu Rev Physiol , vol.75 , pp. 181-200
    • Bautista, D.M.1    Pellegrino, M.2    Tsunozaki, M.3
  • 107
    • 40449121206 scopus 로고    scopus 로고
    • Transient receptor potential A1 is a sensory receptor for multiple products of oxidative stress
    • COI: 1:CAS:528:DC%2BD1cXjt1Ghu7Y%3D, PID: 18322093
    • Andersson DA, Gentry C, Moss S, Bevan S (2008) Transient receptor potential A1 is a sensory receptor for multiple products of oxidative stress. J Neurosci 28:2485–2494
    • (2008) J Neurosci , vol.28 , pp. 2485-2494
    • Andersson, D.A.1    Gentry, C.2    Moss, S.3    Bevan, S.4
  • 108
    • 84860833829 scopus 로고    scopus 로고
    • Oxidative stress induces itch via activation of transient receptor potential subtype ankyrin 1 in mice
    • PID: 22466125
    • Liu T, Ji R-R (2012) Oxidative stress induces itch via activation of transient receptor potential subtype ankyrin 1 in mice. Neurosci Bull 28:145–154
    • (2012) Neurosci Bull , vol.28 , pp. 145-154
    • Liu, T.1    Ji, R.-R.2
  • 109
    • 78049296458 scopus 로고    scopus 로고
    • VGLUT2-dependent sensory neurons in the TRPV1 population regulate pain and itch
    • PID: 21040852
    • Lagerström MC, Rogoz K, Abrahamsen B et al (2010) VGLUT2-dependent sensory neurons in the TRPV1 population regulate pain and itch. Neuron 68:529–542
    • (2010) Neuron , vol.68 , pp. 529-542
    • Lagerström, M.C.1    Rogoz, K.2    Abrahamsen, B.3
  • 110
    • 78049254863 scopus 로고    scopus 로고
    • VGLUT2-dependent glutamate release from nociceptors is required to sense pain and suppress itch
    • COI: 1:CAS:528:DC%2BC3cXhtlKkt7jI, PID: 21040853
    • Liu Y, Abdel Samad O, Zhang L et al (2010) VGLUT2-dependent glutamate release from nociceptors is required to sense pain and suppress itch. Neuron 68:543–556
    • (2010) Neuron , vol.68 , pp. 543-556
    • Liu, Y.1    Abdel Samad, O.2    Zhang, L.3
  • 111
    • 0022637676 scopus 로고
    • The effects of thermal stimulation on clinical and experimental itch
    • COI: 1:STN:280:DyaL287ns1ehsg%3D%3D, PID: 3960572
    • Fruhstorfer H, Hermanns M, Latzke L (1986) The effects of thermal stimulation on clinical and experimental itch. Pain 24:259–269
    • (1986) Pain , vol.24 , pp. 259-269
    • Fruhstorfer, H.1    Hermanns, M.2    Latzke, L.3
  • 112
    • 0028904545 scopus 로고
    • Effects of menthol and cold on histamine-induced itch and skin reactions in man
    • COI: 1:CAS:528:DyaK2MXkvValtLo%3D, PID: 7624016
    • Bromm B, Scharein E, Darsow U, Ring J (1995) Effects of menthol and cold on histamine-induced itch and skin reactions in man. Neurosci Lett 187:157–160
    • (1995) Neurosci Lett , vol.187 , pp. 157-160
    • Bromm, B.1    Scharein, E.2    Darsow, U.3    Ring, J.4
  • 113
    • 84868338495 scopus 로고    scopus 로고
    • Topical TRPM8 agonist (icilin) relieved vulva pruritus originating from lichen sclerosus et atrophicus
    • PID: 22042233
    • Han JH, Choi H-K, Kim SJ (2012) Topical TRPM8 agonist (icilin) relieved vulva pruritus originating from lichen sclerosus et atrophicus. Acta Derm Venereol 92:561–562
    • (2012) Acta Derm Venereol , vol.92 , pp. 561-562
    • Han, J.H.1    Choi, H.-K.2    Kim, S.J.3
  • 114
    • 77953646385 scopus 로고    scopus 로고
    • Therapy of pruritus
    • COI: 1:CAS:528:DC%2BC3cXnsVWgtb4%3D, PID: 20426711
    • Patel T, Yosipovitch G (2010) Therapy of pruritus. Expert Opin Pharmacother 11:1673–1682
    • (2010) Expert Opin Pharmacother , vol.11 , pp. 1673-1682
    • Patel, T.1    Yosipovitch, G.2
  • 115
    • 67349165698 scopus 로고    scopus 로고
    • Relief of itch by scratching: state-dependent inhibition of primate spinothalamic tract neurons
    • COI: 1:CAS:528:DC%2BD1MXktVKgtL0%3D, PID: 19349977
    • Davidson S, Zhang X, Khasabov SG et al (2009) Relief of itch by scratching: state-dependent inhibition of primate spinothalamic tract neurons. Nat Neurosci 12:544–546
    • (2009) Nat Neurosci , vol.12 , pp. 544-546
    • Davidson, S.1    Zhang, X.2    Khasabov, S.G.3
  • 116
    • 79960765251 scopus 로고    scopus 로고
    • Transmitters and pathways mediating inhibition of spinal itch-signaling neurons by scratching and other counterstimuli
    • COI: 1:CAS:528:DC%2BC3MXhtVOisr%2FO, PID: 21818363
    • Akiyama T, Iodi Carstens M, Carstens E (2011) Transmitters and pathways mediating inhibition of spinal itch-signaling neurons by scratching and other counterstimuli. PLoS ONE 6, e22665
    • (2011) PLoS ONE , vol.6
    • Akiyama, T.1    Iodi Carstens, M.2    Carstens, E.3
  • 117
    • 77950218258 scopus 로고    scopus 로고
    • Loss of inhibitory interneurons in the dorsal spinal cord and elevated itch in Bhlhb5 mutant mice
    • COI: 1:CAS:528:DC%2BC3cXlt1Kmtbo%3D, PID: 20346763
    • Ross SE, Mardinly AR, McCord AE et al (2010) Loss of inhibitory interneurons in the dorsal spinal cord and elevated itch in Bhlhb5 mutant mice. Neuron 65:886–898
    • (2010) Neuron , vol.65 , pp. 886-898
    • Ross, S.E.1    Mardinly, A.R.2    McCord, A.E.3
  • 118
    • 0035917683 scopus 로고    scopus 로고
    • Norbinaltorphimine, a selective kappa-opioid receptor antagonist, induces an itch-associated response in mice
    • COI: 1:CAS:528:DC%2BD3MXjtFGntbk%3D, PID: 11334876
    • Kamei J, Nagase H (2001) Norbinaltorphimine, a selective kappa-opioid receptor antagonist, induces an itch-associated response in mice. Eur J Pharmacol 418:141–145
    • (2001) Eur J Pharmacol , vol.418 , pp. 141-145
    • Kamei, J.1    Nagase, H.2
  • 119
    • 84899838945 scopus 로고    scopus 로고
    • Dynorphin acts as a neuromodulator to inhibit itch in the dorsal horn of the spinal cord
    • COI: 1:CAS:528:DC%2BC2cXmtVGhsr4%3D, PID: 24726382
    • Kardon AP, Polgár E, Hachisuka J et al (2014) Dynorphin acts as a neuromodulator to inhibit itch in the dorsal horn of the spinal cord. Neuron 82:573–586
    • (2014) Neuron , vol.82 , pp. 573-586
    • Kardon, A.P.1    Polgár, E.2    Hachisuka, J.3
  • 120
    • 12144287525 scopus 로고    scopus 로고
    • Expression of vanilloid receptor subtype 1 in cutaneous sensory nerve fibers, mast cells, and epithelial cells of appendage structures
    • PID: 14987252
    • Ständer S, Moormann C, Schumacher M et al (2004) Expression of vanilloid receptor subtype 1 in cutaneous sensory nerve fibers, mast cells, and epithelial cells of appendage structures. Exp Dermatol 13:129–139
    • (2004) Exp Dermatol , vol.13 , pp. 129-139
    • Ständer, S.1    Moormann, C.2    Schumacher, M.3
  • 121
    • 15444368320 scopus 로고    scopus 로고
    • Inhibition of scratching behaviour caused by contact dermatitis in histidine decarboxylase gene knockout mice
    • COI: 1:CAS:528:DC%2BD2MXjtFektbY%3D, PID: 15740588
    • Seike M, Ikeda M, Kodama H et al (2005) Inhibition of scratching behaviour caused by contact dermatitis in histidine decarboxylase gene knockout mice. Exp Dermatol 14:169–175
    • (2005) Exp Dermatol , vol.14 , pp. 169-175
    • Seike, M.1    Ikeda, M.2    Kodama, H.3
  • 122
    • 79958822176 scopus 로고    scopus 로고
    • Antipruritic effects of TRPV1 antagonist in murine atopic dermatitis and itching models
    • COI: 1:CAS:528:DC%2BC3MXnsFWgsrc%3D, PID: 21471988
    • Yun J-W, Seo JA, Jang W-H et al (2011) Antipruritic effects of TRPV1 antagonist in murine atopic dermatitis and itching models. J Invest Dermatol 131:1576–1579
    • (2011) J Invest Dermatol , vol.131 , pp. 1576-1579
    • Yun, J.-W.1    Seo, J.A.2    Jang, W.-H.3
  • 123
    • 63849087410 scopus 로고    scopus 로고
    • TRPV1-mediated itch in seasonal allergic rhinitis
    • COI: 1:STN:280:DC%2BD1M3ptVymtQ%3D%3D, PID: 19220220
    • Alenmyr L, Högestätt ED, Zygmunt PM, Greiff L (2009) TRPV1-mediated itch in seasonal allergic rhinitis. Allergy 64:807–810
    • (2009) Allergy , vol.64 , pp. 807-810
    • Alenmyr, L.1    Högestätt, E.D.2    Zygmunt, P.M.3    Greiff, L.4
  • 124
    • 84858299070 scopus 로고    scopus 로고
    • Distribution and expression of non-neuronal transient receptor potential (TRPV) ion channels in rosacea
    • COI: 1:CAS:528:DC%2BC3MXhs1GksLnE, PID: 22189789
    • Sulk M, Seeliger S, Aubert J et al (2012) Distribution and expression of non-neuronal transient receptor potential (TRPV) ion channels in rosacea. J Invest Dermatol 132:1253–1262
    • (2012) J Invest Dermatol , vol.132 , pp. 1253-1262
    • Sulk, M.1    Seeliger, S.2    Aubert, J.3
  • 125
    • 84888332336 scopus 로고    scopus 로고
    • Impact of TRPV3 on the development of allergic dermatitis as a dendritic cell modulator
    • COI: 1:CAS:528:DC%2BC3sXhvVGkurjI, PID: 24164484
    • Yamamoto-Kasai E, Yasui K, Shichijo M et al (2013) Impact of TRPV3 on the development of allergic dermatitis as a dendritic cell modulator. Exp Dermatol 22:820–824
    • (2013) Exp Dermatol , vol.22 , pp. 820-824
    • Yamamoto-Kasai, E.1    Yasui, K.2    Shichijo, M.3
  • 126
    • 84918805697 scopus 로고    scopus 로고
    • Increased expression of three types of transient receptor potential channels (TRPA1, TRPV4 and TRPV3) in burn scars with post-burn pruritus
    • PID: 24695993
    • Yang YS, Cho SI, Choi MG et al (2015) Increased expression of three types of transient receptor potential channels (TRPA1, TRPV4 and TRPV3) in burn scars with post-burn pruritus. Acta Derm Venereol 95:20–24
    • (2015) Acta Derm Venereol , vol.95 , pp. 20-24
    • Yang, Y.S.1    Cho, S.I.2    Choi, M.G.3
  • 127
    • 0037077041 scopus 로고    scopus 로고
    • A heat-sensitive TRP channel expressed in keratinocytes
    • COI: 1:CAS:528:DC%2BD38Xks1GitLs%3D, PID: 12016205
    • Peier AM, Reeve AJ, Andersson DA et al (2002) A heat-sensitive TRP channel expressed in keratinocytes. Science 296:2046–2049
    • (2002) Science , vol.296 , pp. 2046-2049
    • Peier, A.M.1    Reeve, A.J.2    Andersson, D.A.3
  • 128
    • 33847080874 scopus 로고    scopus 로고
    • Effects of skin surface temperature on epidermal permeability barrier homeostasis
    • COI: 1:CAS:528:DC%2BD2sXhs1Crtrs%3D, PID: 17068482
    • Denda M, Sokabe T, Fukumi-Tominaga T, Tominaga M (2007) Effects of skin surface temperature on epidermal permeability barrier homeostasis. J Invest Dermatol 127:654–659
    • (2007) J Invest Dermatol , vol.127 , pp. 654-659
    • Denda, M.1    Sokabe, T.2    Fukumi-Tominaga, T.3    Tominaga, M.4
  • 129
    • 58149396234 scopus 로고    scopus 로고
    • Overexpressed transient receptor potential vanilloid 3 ion channels in skin keratinocytes modulate pain sensitivity via prostaglandin E2
    • COI: 1:CAS:528:DC%2BD1cXhsFCqtrjE, PID: 19091963
    • Huang SM, Lee H, Chung M-K et al (2008) Overexpressed transient receptor potential vanilloid 3 ion channels in skin keratinocytes modulate pain sensitivity via prostaglandin E2. J Neurosci 28:13727–13737
    • (2008) J Neurosci , vol.28 , pp. 13727-13737
    • Huang, S.M.1    Lee, H.2    Chung, M.-K.3
  • 130
    • 70349577888 scopus 로고    scopus 로고
    • TRPV3 in keratinocytes transmits temperature information to sensory neurons via ATP
    • COI: 1:CAS:528:DC%2BD1MXhtFensbjL, PID: 19669158
    • Mandadi S, Sokabe T, Shibasaki K et al (2009) TRPV3 in keratinocytes transmits temperature information to sensory neurons via ATP. Pflugers Arch 458:1093–1102
    • (2009) Pflugers Arch , vol.458 , pp. 1093-1102
    • Mandadi, S.1    Sokabe, T.2    Shibasaki, K.3
  • 131
    • 84880308811 scopus 로고    scopus 로고
    • TRPV3 regulates nitric oxide synthase-independent nitric oxide synthesis in the skin
    • PID: 21712817
    • Miyamoto T, Petrus MJ, Dubin AE, Patapoutian A (2011) TRPV3 regulates nitric oxide synthase-independent nitric oxide synthesis in the skin. Nat Commun 2:369
    • (2011) Nat Commun , vol.2 , pp. 369
    • Miyamoto, T.1    Petrus, M.J.2    Dubin, A.E.3    Patapoutian, A.4
  • 132
    • 59949095113 scopus 로고    scopus 로고
    • Impact of the Gly573Ser substitution in TRPV3 on the development of allergic and pruritic dermatitis in mice
    • COI: 1:CAS:528:DC%2BD1MXhslShtrk%3D, PID: 18754035
    • Yoshioka T, Imura K, Asakawa M et al (2009) Impact of the Gly573Ser substitution in TRPV3 on the development of allergic and pruritic dermatitis in mice. J Invest Dermatol 129:714–722
    • (2009) J Invest Dermatol , vol.129 , pp. 714-722
    • Yoshioka, T.1    Imura, K.2    Asakawa, M.3
  • 133
    • 33751112985 scopus 로고    scopus 로고
    • Association of a mutation in TRPV3 with defective hair growth in rodents
    • COI: 1:CAS:528:DC%2BD28Xht1Sgt7nL, PID: 16858425
    • Asakawa M, Yoshioka T, Matsutani T et al (2006) Association of a mutation in TRPV3 with defective hair growth in rodents. J Invest Dermatol 126:2664–2672
    • (2006) J Invest Dermatol , vol.126 , pp. 2664-2672
    • Asakawa, M.1    Yoshioka, T.2    Matsutani, T.3
  • 134
    • 84863251177 scopus 로고    scopus 로고
    • Exome sequencing reveals mutations in TRPV3 as a cause of Olmsted syndrome
    • COI: 1:CAS:528:DC%2BC38XjsFOjsro%3D, PID: 22405088
    • Lin Z, Chen Q, Lee M et al (2012) Exome sequencing reveals mutations in TRPV3 as a cause of Olmsted syndrome. Am J Hum Genet 90:558–564
    • (2012) Am J Hum Genet , vol.90 , pp. 558-564
    • Lin, Z.1    Chen, Q.2    Lee, M.3
  • 135
    • 84864402775 scopus 로고    scopus 로고
    • Recurrent heterozygous missense mutation, p.Gly573Ser, in the TRPV3 gene in an Indian boy with sporadic Olmsted syndrome
    • COI: 1:CAS:528:DC%2BC38XhtFWns7vK, PID: 22835024
    • Lai-Cheong JE, Sethuraman G, Ramam M et al (2012) Recurrent heterozygous missense mutation, p.Gly573Ser, in the TRPV3 gene in an Indian boy with sporadic Olmsted syndrome. Br J Dermatol 167:440–442
    • (2012) Br J Dermatol , vol.167 , pp. 440-442
    • Lai-Cheong, J.E.1    Sethuraman, G.2    Ramam, M.3
  • 136
    • 0034306198 scopus 로고    scopus 로고
    • OTRPC4, a nonselective cation channel that confers sensitivity to extracellular osmolarity
    • COI: 1:CAS:528:DC%2BD3cXnsVyntL8%3D, PID: 11025659
    • Strotmann R, Harteneck C, Nunnenmacher K et al (2000) OTRPC4, a nonselective cation channel that confers sensitivity to extracellular osmolarity. Nat Cell Biol 2:695–702
    • (2000) Nat Cell Biol , vol.2 , pp. 695-702
    • Strotmann, R.1    Harteneck, C.2    Nunnenmacher, K.3
  • 137
    • 0034721648 scopus 로고    scopus 로고
    • Vanilloid receptor-related osmotically activated channel (VR-OAC), a candidate vertebrate osmoreceptor
    • COI: 1:CAS:528:DC%2BD3cXnvF2ksbs%3D, PID: 11081638
    • Liedtke W, Choe Y, Martí-Renom MA et al (2000) Vanilloid receptor-related osmotically activated channel (VR-OAC), a candidate vertebrate osmoreceptor. Cell 103:525–535
    • (2000) Cell , vol.103 , pp. 525-535
    • Liedtke, W.1    Choe, Y.2    Martí-Renom, M.A.3
  • 138
    • 0041355261 scopus 로고    scopus 로고
    • Warm temperatures activate TRPV4 in mouse 308 keratinocytes
    • COI: 1:CAS:528:DC%2BD3sXmsVOmsrg%3D, PID: 12783886
    • Chung M-K, Lee H, Caterina MJ (2003) Warm temperatures activate TRPV4 in mouse 308 keratinocytes. J Biol Chem 278:32037–32046
    • (2003) J Biol Chem , vol.278 , pp. 32037-32046
    • Chung, M.-K.1    Lee, H.2    Caterina, M.J.3
  • 139
    • 0036703646 scopus 로고    scopus 로고
    • Heat-evoked activation of the ion channel, TRPV4
    • PID: 12151520
    • Güler AD, Lee H, Iida T et al (2002) Heat-evoked activation of the ion channel, TRPV4. J Neurosci 22:6408–6414
    • (2002) J Neurosci , vol.22 , pp. 6408-6414
    • Güler, A.D.1    Lee, H.2    Iida, T.3
  • 140
    • 77953316839 scopus 로고    scopus 로고
    • The TRPV4 channel contributes to intercellular junction formation in keratinocytes
    • COI: 1:CAS:528:DC%2BC3cXmvFaqsbc%3D, PID: 20413591
    • Sokabe T, Fukumi-Tominaga T, Yonemura S et al (2010) The TRPV4 channel contributes to intercellular junction formation in keratinocytes. J Biol Chem 285:18749–18758
    • (2010) J Biol Chem , vol.285 , pp. 18749-18758
    • Sokabe, T.1    Fukumi-Tominaga, T.2    Yonemura, S.3
  • 141
    • 42149135958 scopus 로고    scopus 로고
    • TRPC channels determine human keratinocyte differentiation: new insight into basal cell carcinoma
    • COI: 1:CAS:528:DC%2BD1cXkvFGit78%3D, PID: 17920677
    • Beck B, Lehen’kyi V, Roudbaraki M et al (2008) TRPC channels determine human keratinocyte differentiation: new insight into basal cell carcinoma. Cell Calcium 43:492–505
    • (2008) Cell Calcium , vol.43 , pp. 492-505
    • Beck, B.1    Lehen’kyi, V.2    Roudbaraki, M.3
  • 142
    • 57749084622 scopus 로고    scopus 로고
    • Specific TRPC6 channel activation, a novel approach to stimulate keratinocyte differentiation
    • PID: 18818211
    • Müller M, Essin K, Hill K et al (2008) Specific TRPC6 channel activation, a novel approach to stimulate keratinocyte differentiation. J Biol Chem 283:33942–33954
    • (2008) J Biol Chem , vol.283 , pp. 33942-33954
    • Müller, M.1    Essin, K.2    Hill, K.3
  • 143
    • 79952055407 scopus 로고    scopus 로고
    • Reduced TRPC channel expression in psoriatic keratinocytes is associated with impaired differentiation and enhanced proliferation
    • COI: 1:CAS:528:DC%2BC3MXivVymuro%3D, PID: 21364982
    • Leuner K, Kraus M, Woelfle U et al (2011) Reduced TRPC channel expression in psoriatic keratinocytes is associated with impaired differentiation and enhanced proliferation. PLoS ONE 6, e14716
    • (2011) PLoS ONE , vol.6
    • Leuner, K.1    Kraus, M.2    Woelfle, U.3
  • 144
    • 0036780395 scopus 로고    scopus 로고
    • Pruritic linear papules on a 75-year-old woman: a case of localized Darier-White disease
    • PID: 12403314
    • Barfield RL, Barrett KR, Moon CM, David-Bajar K (2002) Pruritic linear papules on a 75-year-old woman: a case of localized Darier-White disease. Cutis 70:225–228
    • (2002) Cutis , vol.70 , pp. 225-228
    • Barfield, R.L.1    Barrett, K.R.2    Moon, C.M.3    David-Bajar, K.4
  • 145
    • 33749500948 scopus 로고    scopus 로고
    • Up-regulation of transient receptor potential canonical 1 (TRPC1) following sarco(endo)plasmic reticulum Ca2+ ATPase 2 gene silencing promotes cell survival: a potential role for TRPC1 in Darier’s disease
    • COI: 1:CAS:528:DC%2BD28XhtFSjt7fL, PID: 16899508
    • Pani B, Cornatzer E, Cornatzer W et al (2006) Up-regulation of transient receptor potential canonical 1 (TRPC1) following sarco(endo)plasmic reticulum Ca2+ ATPase 2 gene silencing promotes cell survival: a potential role for TRPC1 in Darier’s disease. Mol Biol Cell 17:4446–4458
    • (2006) Mol Biol Cell , vol.17 , pp. 4446-4458
    • Pani, B.1    Cornatzer, E.2    Cornatzer, W.3
  • 146
    • 2342634417 scopus 로고    scopus 로고
    • Involvement of substance P in scratching behaviour in an atopic dermatitis model
    • COI: 1:CAS:528:DC%2BD2cXktVCqsr0%3D, PID: 15140636
    • Ohmura T, Hayashi T, Satoh Y et al (2004) Involvement of substance P in scratching behaviour in an atopic dermatitis model. Eur J Pharmacol 491:191–194
    • (2004) Eur J Pharmacol , vol.491 , pp. 191-194
    • Ohmura, T.1    Hayashi, T.2    Satoh, Y.3
  • 147
    • 84882782663 scopus 로고    scopus 로고
    • TRPA1 controls inflammation and pruritogen responses in allergic contact dermatitis
    • COI: 1:CAS:528:DC%2BC3sXhsVaitLzE, PID: 23722916
    • Liu B, Escalera J, Balakrishna S et al (2013) TRPA1 controls inflammation and pruritogen responses in allergic contact dermatitis. FASEB J 27:3549–3563
    • (2013) FASEB J , vol.27 , pp. 3549-3563
    • Liu, B.1    Escalera, J.2    Balakrishna, S.3
  • 148
    • 77949541373 scopus 로고    scopus 로고
    • The histamine H4 receptor mediates inflammation and pruritus in Th2-dependent dermal inflammation
    • COI: 1:CAS:528:DC%2BC3cXjt1Kqu78%3D, PID: 19907432
    • Cowden JM, Zhang M, Dunford PJ, Thurmond RL (2010) The histamine H4 receptor mediates inflammation and pruritus in Th2-dependent dermal inflammation. J Invest Dermatol 130:1023–1033
    • (2010) J Invest Dermatol , vol.130 , pp. 1023-1033
    • Cowden, J.M.1    Zhang, M.2    Dunford, P.J.3    Thurmond, R.L.4
  • 149
    • 0036213007 scopus 로고    scopus 로고
    • Itch-associated response induced by experimental dry skin in mice
    • COI: 1:CAS:528:DC%2BD38Xis1Wktrk%3D, PID: 11949883
    • Miyamoto T, Nojima H, Shinkado T et al (2002) Itch-associated response induced by experimental dry skin in mice. Jpn J Pharmacol 88:285–292
    • (2002) Jpn J Pharmacol , vol.88 , pp. 285-292
    • Miyamoto, T.1    Nojima, H.2    Shinkado, T.3
  • 150
    • 79959343109 scopus 로고    scopus 로고
    • Spontaneous itch in the absence of hyperalgesia in a mouse hindpaw dry skin model
    • COI: 1:CAS:528:DC%2BC3cXhtFGjurzK, PID: 20709155
    • Akiyama T, Carstens MI, Carstens E (2010) Spontaneous itch in the absence of hyperalgesia in a mouse hindpaw dry skin model. Neurosci Lett 484:62–65
    • (2010) Neurosci Lett , vol.484 , pp. 62-65
    • Akiyama, T.1    Carstens, M.I.2    Carstens, E.3
  • 151
    • 84878331790 scopus 로고    scopus 로고
    • The ion channel TRPA1 is required for chronic itch
    • COI: 1:CAS:528:DC%2BC3sXovFerurc%3D, PID: 23719797
    • Wilson SR, Nelson AM, Batia L et al (2013) The ion channel TRPA1 is required for chronic itch. J Neurosci 33:9283–9294
    • (2013) J Neurosci , vol.33 , pp. 9283-9294
    • Wilson, S.R.1    Nelson, A.M.2    Batia, L.3
  • 152
    • 84863983852 scopus 로고    scopus 로고
    • TRPV3 as a therapeutic target for itch
    • COI: 1:CAS:528:DC%2BC38XkvFyqsb4%3D, PID: 22475759
    • Yamamoto-Kasai E, Imura K, Yasui K et al (2012) TRPV3 as a therapeutic target for itch. J Invest Dermatol 132:2109–2112
    • (2012) J Invest Dermatol , vol.132 , pp. 2109-2112
    • Yamamoto-Kasai, E.1    Imura, K.2    Yasui, K.3
  • 153
    • 77951756662 scopus 로고    scopus 로고
    • TRP channel regulates EGFR signaling in hair morphogenesis and skin barrier formation
    • COI: 1:CAS:528:DC%2BC3cXmtVWnsb4%3D, PID: 20403327
    • Cheng X, Jin J, Hu L et al (2010) TRP channel regulates EGFR signaling in hair morphogenesis and skin barrier formation. Cell 141:331–343
    • (2010) Cell , vol.141 , pp. 331-343
    • Cheng, X.1    Jin, J.2    Hu, L.3
  • 154
    • 80051605343 scopus 로고    scopus 로고
    • Itch signaling in the nervous system
    • COI: 1:CAS:528:DC%2BC3MXht1Shtr7N
    • Jeffry J, Kim S, Chen Z-F (2011) Itch signaling in the nervous system. Physiology (Bethesda) 26:286–292
    • (2011) Physiology (Bethesda) , vol.26 , pp. 286-292
    • Jeffry, J.1    Kim, S.2    Chen, Z.-F.3
  • 155
    • 77957891302 scopus 로고    scopus 로고
    • Enhanced scratching evoked by PAR-2 agonist and 5-HT but not histamine in a mouse model of chronic dry skin itch
    • COI: 1:CAS:528:DC%2BC3cXhtlSmtbnN, PID: 20709455
    • Akiyama T, Carstens MI, Carstens E (2010) Enhanced scratching evoked by PAR-2 agonist and 5-HT but not histamine in a mouse model of chronic dry skin itch. Pain 151:378–383
    • (2010) Pain , vol.151 , pp. 378-383
    • Akiyama, T.1    Carstens, M.I.2    Carstens, E.3
  • 156
    • 58549088980 scopus 로고    scopus 로고
    • Evolving concepts of pathogenesis in atopic dermatitis and other eczemas
    • COI: 1:CAS:528:DC%2BD1MXmt1Ggug%3D%3D, PID: 18719604
    • Hanifin JM (2009) Evolving concepts of pathogenesis in atopic dermatitis and other eczemas. J Invest Dermatol 129:320–322
    • (2009) J Invest Dermatol , vol.129 , pp. 320-322
    • Hanifin, J.M.1
  • 157
    • 77953613538 scopus 로고    scopus 로고
    • Topical application of TRPA1 agonists and brief cold exposure accelerate skin permeability barrier recovery
    • COI: 1:CAS:528:DC%2BC3cXnsVyisb0%3D, PID: 20182443
    • Denda M, Tsutsumi M, Goto M et al (2010) Topical application of TRPA1 agonists and brief cold exposure accelerate skin permeability barrier recovery. J Invest Dermatol 130:1942–1945
    • (2010) J Invest Dermatol , vol.130 , pp. 1942-1945
    • Denda, M.1    Tsutsumi, M.2    Goto, M.3
  • 158
    • 79960997710 scopus 로고    scopus 로고
    • Transient receptor potential channels as therapeutic targets
    • COI: 1:CAS:528:DC%2BC3MXpsFOjs7Y%3D, PID: 21804597
    • Moran MM, McAlexander MA, Bíró T, Szallasi A (2011) Transient receptor potential channels as therapeutic targets. Nat Rev Drug Discov 10:601–620
    • (2011) Nat Rev Drug Discov , vol.10 , pp. 601-620
    • Moran, M.M.1    McAlexander, M.A.2    Bíró, T.3    Szallasi, A.4
  • 159
    • 84862869336 scopus 로고    scopus 로고
    • Development of PAC-14028, a novel transient receptor potential vanilloid type 1 (TRPV1) channel antagonist as a new drug for refractory skin diseases
    • COI: 1:CAS:528:DC%2BC38XltVKgs7o%3D, PID: 22477184
    • Lim K-M, Park Y-H (2012) Development of PAC-14028, a novel transient receptor potential vanilloid type 1 (TRPV1) channel antagonist as a new drug for refractory skin diseases. Arch Pharm Res 35:393–396
    • (2012) Arch Pharm Res , vol.35 , pp. 393-396
    • Lim, K.-M.1    Park, Y.-H.2
  • 160
    • 84899107723 scopus 로고    scopus 로고
    • Inhibition of capsaicin-driven nasal hyper-reactivity by SB-705498, a TRPV1 antagonist
    • COI: 1:CAS:528:DC%2BC2cXmvVyrtrw%3D, PID: 23909699
    • Holland C, van Drunen C, Denyer J et al (2014) Inhibition of capsaicin-driven nasal hyper-reactivity by SB-705498, a TRPV1 antagonist. Br J Clin Pharmacol 77:777–788
    • (2014) Br J Clin Pharmacol , vol.77 , pp. 777-788
    • Holland, C.1    van Drunen, C.2    Denyer, J.3
  • 161
    • 84880223161 scopus 로고    scopus 로고
    • The effects of a TRPV1 antagonist, SB-705498, in the treatment of seasonal allergic rhinitis
    • COI: 1:CAS:528:DC%2BC3sXhsVaqsLjE, PID: 23735181
    • Bareille P, Murdoch RD, Denyer J et al (2013) The effects of a TRPV1 antagonist, SB-705498, in the treatment of seasonal allergic rhinitis. Int J Clin Pharmacol Ther 51:576–584
    • (2013) Int J Clin Pharmacol Ther , vol.51 , pp. 576-584
    • Bareille, P.1    Murdoch, R.D.2    Denyer, J.3
  • 162
    • 84904698744 scopus 로고    scopus 로고
    • A randomised trial evaluating the effects of the TRPV1 antagonist SB705498 on pruritus induced by histamine, and cowhage challenge in healthy volunteers
    • PID: 25047038
    • Gibson RA, Robertson J, Mistry H et al (2014) A randomised trial evaluating the effects of the TRPV1 antagonist SB705498 on pruritus induced by histamine, and cowhage challenge in healthy volunteers. PLoS ONE 9, e100610
    • (2014) PLoS ONE , vol.9
    • Gibson, R.A.1    Robertson, J.2    Mistry, H.3
  • 163
    • 38549118896 scopus 로고    scopus 로고
    • Capsaicin (TRPV1 Agonist) therapy for pain relief: farewell or revival?
    • PID: 18209521
    • Knotkova H, Pappagallo M, Szallasi A (2008) Capsaicin (TRPV1 Agonist) therapy for pain relief: farewell or revival? Clin J Pain 24:142–154
    • (2008) Clin J Pain , vol.24 , pp. 142-154
    • Knotkova, H.1    Pappagallo, M.2    Szallasi, A.3
  • 164
    • 0035106681 scopus 로고    scopus 로고
    • Treatment of prurigo nodularis with topical capsaicin
    • PID: 11209117
    • Ständer S, Luger T, Metze D (2001) Treatment of prurigo nodularis with topical capsaicin. J Am Acad Dermatol 44:471–478
    • (2001) J Am Acad Dermatol , vol.44 , pp. 471-478
    • Ständer, S.1    Luger, T.2    Metze, D.3
  • 165
    • 0027184020 scopus 로고
    • A double-blind evaluation of topical capsaicin in pruritic psoriasis
    • COI: 1:STN:280:DyaK3szlt1yqsw%3D%3D, PID: 7688774
    • Ellis CN, Berberian B, Sulica VI et al (1993) A double-blind evaluation of topical capsaicin in pruritic psoriasis. J Am Acad Dermatol 29:438–442
    • (1993) J Am Acad Dermatol , vol.29 , pp. 438-442
    • Ellis, C.N.1    Berberian, B.2    Sulica, V.I.3
  • 166
    • 0041507034 scopus 로고    scopus 로고
    • Topical capsaicin—a novel and effective treatment for idiopathic intractable pruritus ani: a randomised, placebo controlled, crossover study
    • COI: 1:CAS:528:DC%2BD3sXnsFCgtL0%3D, PID: 12912865
    • Lysy J, Sistiery-Ittah M, Israelit Y et al (2003) Topical capsaicin—a novel and effective treatment for idiopathic intractable pruritus ani: a randomised, placebo controlled, crossover study. Gut 52:1323–1326
    • (2003) Gut , vol.52 , pp. 1323-1326
    • Lysy, J.1    Sistiery-Ittah, M.2    Israelit, Y.3
  • 167
    • 77953174427 scopus 로고    scopus 로고
    • Topical capsaicin therapy for uremic pruritus in patients on hemodialysis
    • PID: 20404425
    • Makhlough A, Ala S, Haj-Heydari Z et al (2010) Topical capsaicin therapy for uremic pruritus in patients on hemodialysis. Iran J Kidney Dis 4:137–140
    • (2010) Iran J Kidney Dis , vol.4 , pp. 137-140
    • Makhlough, A.1    Ala, S.2    Haj-Heydari, Z.3
  • 168
    • 77954924312 scopus 로고    scopus 로고
    • Systematic review of topical capsaicin in the treatment of pruritus
    • PID: 21128913
    • Gooding SMD, Canter PH, Coelho HF et al (2010) Systematic review of topical capsaicin in the treatment of pruritus. Int J Dermatol 49:858–865
    • (2010) Int J Dermatol , vol.49 , pp. 858-865
    • Gooding, S.M.D.1    Canter, P.H.2    Coelho, H.F.3
  • 169
    • 34249721652 scopus 로고    scopus 로고
    • Phenol and menthol in the treatment of chronic skin lesions following mustard gas exposure
    • COI: 1:STN:280:DC%2BD2s3ksVWjtQ%3D%3D
    • Panahi Y, Davoodi SM, Khalili H et al (2007) Phenol and menthol in the treatment of chronic skin lesions following mustard gas exposure. Singap Med J 48:392–395
    • (2007) Singap Med J , vol.48 , pp. 392-395
    • Panahi, Y.1    Davoodi, S.M.2    Khalili, H.3
  • 170
    • 70350157082 scopus 로고    scopus 로고
    • Successful treatment of therapy-resistant pruritus in lichen amyloidosis with menthol
    • PID: 19734984
    • Frölich M, Enk A, Diepgen TL, Weisshaar E (2009) Successful treatment of therapy-resistant pruritus in lichen amyloidosis with menthol. Acta Derm Venereol 89:524–526
    • (2009) Acta Derm Venereol , vol.89 , pp. 524-526
    • Frölich, M.1    Enk, A.2    Diepgen, T.L.3    Weisshaar, E.4
  • 171
    • 45049083554 scopus 로고    scopus 로고
    • Hydroxyethyl starch-induced pruritus relieved by a combination of menthol and camphor
    • PID: 18455262
    • Haught JM, Jukic DM, English JC (2008) Hydroxyethyl starch-induced pruritus relieved by a combination of menthol and camphor. J Am Acad Dermatol 59:151–153
    • (2008) J Am Acad Dermatol , vol.59 , pp. 151-153
    • Haught, J.M.1    Jukic, D.M.2    English, J.C.3
  • 172
    • 34548617428 scopus 로고    scopus 로고
    • The itch-producing agents histamine and cowhage activate separate populations of primate spinothalamic tract neurons
    • COI: 1:CAS:528:DC%2BD2sXhtVyksbnO, PID: 17855615
    • Davidson S, Zhang X, Yoon CH et al (2007) The itch-producing agents histamine and cowhage activate separate populations of primate spinothalamic tract neurons. J Neurosci 27:10007–10014
    • (2007) J Neurosci , vol.27 , pp. 10007-10014
    • Davidson, S.1    Zhang, X.2    Yoon, C.H.3
  • 173
    • 84866396893 scopus 로고    scopus 로고
    • Pruriceptive spinothalamic tract neurons: physiological properties and projection targets in the primate
    • PID: 22723676
    • Davidson S, Zhang X, Khasabov SG et al (2012) Pruriceptive spinothalamic tract neurons: physiological properties and projection targets in the primate. J Neurophysiol 108:1711–1723
    • (2012) J Neurophysiol , vol.108 , pp. 1711-1723
    • Davidson, S.1    Zhang, X.2    Khasabov, S.G.3
  • 174
    • 84921466417 scopus 로고    scopus 로고
    • Unbiased classification of sensory neuron types by large-scale single-cell RNA sequencing
    • PID: 25420068
    • Usoskin D, Furlan A, Islam S et al (2014) Unbiased classification of sensory neuron types by large-scale single-cell RNA sequencing. Nat Neurosci 18:145–153
    • (2014) Nat Neurosci , vol.18 , pp. 145-153
    • Usoskin, D.1    Furlan, A.2    Islam, S.3
  • 175
    • 33745656971 scopus 로고    scopus 로고
    • Cysteinyl leukotrienes: multi-functional mediators in allergic rhinitis
    • COI: 1:CAS:528:DC%2BD28Xntlymtrs%3D, PID: 16776669
    • Peters-Golden M, Gleason MM, Togias A (2006) Cysteinyl leukotrienes: multi-functional mediators in allergic rhinitis. Clin Exp Allergy 36:689–703
    • (2006) Clin Exp Allergy , vol.36 , pp. 689-703
    • Peters-Golden, M.1    Gleason, M.M.2    Togias, A.3
  • 176
    • 78349236257 scopus 로고    scopus 로고
    • The employment of leukotriene antagonists in cutaneous diseases belonging to allergological field. Mediat Inflamm
    • Nettis E, D’Erasmo M, Di Leo E, et al. (2010) The employment of leukotriene antagonists in cutaneous diseases belonging to allergological field. Mediat Inflamm. doi:10.1155/2010/628171
    • (2010) doi:10.1155/2010/628171
    • Nettis, E.1    D’Erasmo, M.2    Di Leo, E.3
  • 177
    • 24744470041 scopus 로고    scopus 로고
    • Successful treatment of severe atopic dermatitis with cysteinyl leukotriene receptor antagonist montelukast
    • Angelova-Fischer I, Tsankov N (2005) Successful treatment of severe atopic dermatitis with cysteinyl leukotriene receptor antagonist montelukast. Acta Dermatovenerol Alpina, Pannonica, Adriat 14:115–119
    • (2005) Acta Dermatovenerol Alpina, Pannonica, Adriat , vol.14 , pp. 115-119
    • Angelova-Fischer, I.1    Tsankov, N.2
  • 178
    • 84877939975 scopus 로고    scopus 로고
    • The cells and circuitry for itch responses in mice
    • COI: 1:CAS:528:DC%2BC3sXnvFSrt70%3D, PID: 23704570
    • Mishra SK, Hoon MA (2013) The cells and circuitry for itch responses in mice. Science 340:968–971
    • (2013) Science , vol.340 , pp. 968-971
    • Mishra, S.K.1    Hoon, M.A.2
  • 179
    • 37749048627 scopus 로고    scopus 로고
    • The role of histamine H1 and H4 receptors in allergic inflammation: the search for new antihistamines
    • COI: 1:CAS:528:DC%2BD1cXht1ygsQ%3D%3D, PID: 18172439
    • Thurmond RL, Gelfand EW, Dunford PJ (2008) The role of histamine H1 and H4 receptors in allergic inflammation: the search for new antihistamines. Nat Rev Drug Discov 7:41–53
    • (2008) Nat Rev Drug Discov , vol.7 , pp. 41-53
    • Thurmond, R.L.1    Gelfand, E.W.2    Dunford, P.J.3
  • 180
    • 46249119396 scopus 로고    scopus 로고
    • Involvement of the BLT2 receptor in the itch-associated scratching induced by 12-(S)-lipoxygenase products in ICR mice
    • COI: 1:CAS:528:DC%2BD1cXnvVGqsrY%3D, PID: 18536755
    • Kim HJ, Kim DK, Kim H et al (2008) Involvement of the BLT2 receptor in the itch-associated scratching induced by 12-(S)-lipoxygenase products in ICR mice. Br J Pharmacol 154:1073–1078
    • (2008) Br J Pharmacol , vol.154 , pp. 1073-1078
    • Kim, H.J.1    Kim, D.K.2    Kim, H.3
  • 181
    • 37549070754 scopus 로고    scopus 로고
    • Involvement of serotonin receptors 5-HT1 and 5-HT2 in 12(S)-HPETE-induced scratching in mice
    • COI: 1:CAS:528:DC%2BD1cXivVOitw%3D%3D, PID: 18037400
    • Kim D-K, Kim H-J, Kim H et al (2008) Involvement of serotonin receptors 5-HT1 and 5-HT2 in 12(S)-HPETE-induced scratching in mice. Eur J Pharmacol 579:390–394
    • (2008) Eur J Pharmacol , vol.579 , pp. 390-394
    • Kim, D.-K.1    Kim, H.-J.2    Kim, H.3
  • 182
    • 84867576847 scopus 로고    scopus 로고
    • Endothelin-1 induces itch and pain in the mouse cheek model
    • COI: 1:CAS:528:DC%2BC38XlvVSntL4%3D, PID: 22483687
    • Gomes LO, Hara DB, Rae GA (2012) Endothelin-1 induces itch and pain in the mouse cheek model. Life Sci 91:628–633
    • (2012) Life Sci , vol.91 , pp. 628-633
    • Gomes, L.O.1    Hara, D.B.2    Rae, G.A.3
  • 183
    • 34447534299 scopus 로고    scopus 로고
    • Thromboxane A2 induces itch-associated responses through TP receptors in the skin in mice
    • COI: 1:CAS:528:DC%2BD2sXns1ymu7Y%3D, PID: 17429442
    • Andoh T, Nishikawa Y, Yamaguchi-Miyamoto T et al (2007) Thromboxane A2 induces itch-associated responses through TP receptors in the skin in mice. J Invest Dermatol 127:2042–2047
    • (2007) J Invest Dermatol , vol.127 , pp. 2042-2047
    • Andoh, T.1    Nishikawa, Y.2    Yamaguchi-Miyamoto, T.3
  • 184
    • 79958111386 scopus 로고    scopus 로고
    • Functional effects of interleukin 31 in human primary keratinocytes
    • COI: 1:CAS:528:DC%2BC3MXpsVGjsbs%3D, PID: 21261663
    • Kasraie S, Niebuhr M, Baumert K, Werfel T (2011) Functional effects of interleukin 31 in human primary keratinocytes. Allergy 66:845–852
    • (2011) Allergy , vol.66 , pp. 845-852
    • Kasraie, S.1    Niebuhr, M.2    Baumert, K.3    Werfel, T.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.