메뉴 건너뛰기




Volumn 44, Issue 10, 2007, Pages 2497-2506

Cytokine receptor signaling through the Jak-Stat-Socs pathway in disease

Author keywords

Cytokine receptor; Inflammatory diseases; Jak Stat Socs

Indexed keywords

CYTOKINE RECEPTOR; INTERLEUKIN 2 RECEPTOR ANTIBODY; INTERLEUKIN RECEPTOR; JANUS KINASE; STAT PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING; VIRUS RECEPTOR;

EID: 33846903838     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2006.11.025     Document Type: Review
Times cited : (289)

References (105)
  • 2
    • 0025162844 scopus 로고
    • Structural design and molecular evolution of a cytokine receptor superfamily
    • Bazan J.F. Structural design and molecular evolution of a cytokine receptor superfamily. Proc. Natl. Acad. Sci. U.S.A. 87 (1990) 6934-6938
    • (1990) Proc. Natl. Acad. Sci. U.S.A. , vol.87 , pp. 6934-6938
    • Bazan, J.F.1
  • 4
    • 0032460226 scopus 로고    scopus 로고
    • Prolactin (PRL) and its receptor: actions, signal transduction pathways and phenotypes observed in PRL receptor knockout mice
    • Bole-Feysot C., Goffin V., Edery M., Binart N., and Kelly P.A. Prolactin (PRL) and its receptor: actions, signal transduction pathways and phenotypes observed in PRL receptor knockout mice. Endocr. Rev. 19 (1998) 225-268
    • (1998) Endocr. Rev. , vol.19 , pp. 225-268
    • Bole-Feysot, C.1    Goffin, V.2    Edery, M.3    Binart, N.4    Kelly, P.A.5
  • 5
    • 0042932806 scopus 로고    scopus 로고
    • Molecular phylogeny within type I cytokines and their cognate receptors
    • Boulay J.L., O'Shea J.J., and Paul W.E. Molecular phylogeny within type I cytokines and their cognate receptors. Immunity 19 (2003) 159-163
    • (2003) Immunity , vol.19 , pp. 159-163
    • Boulay, J.L.1    O'Shea, J.J.2    Paul, W.E.3
  • 7
    • 0032805660 scopus 로고    scopus 로고
    • Constitutive activation of Stats upon in vivo human immunodeficiency virus infection
    • Bovolenta C., Camorali L., Lorini A.L., Ghezzi S., Vicenzi E., Lazzarin A., and Poli G. Constitutive activation of Stats upon in vivo human immunodeficiency virus infection. Blood 12 (1999) 4202-4209
    • (1999) Blood , vol.12 , pp. 4202-4209
    • Bovolenta, C.1    Camorali, L.2    Lorini, A.L.3    Ghezzi, S.4    Vicenzi, E.5    Lazzarin, A.6    Poli, G.7
  • 8
    • 2542461255 scopus 로고    scopus 로고
    • Molecular defects in human severe combined immunodeficiency and approaches to immune reconstitution
    • Buckley R.H. Molecular defects in human severe combined immunodeficiency and approaches to immune reconstitution. Annu. Rev. Immunol. 22 (2004) 625-655
    • (2004) Annu. Rev. Immunol. , vol.22 , pp. 625-655
    • Buckley, R.H.1
  • 14
    • 0031718359 scopus 로고    scopus 로고
    • Regulation of proliferation, differentiation and survival by the IL-3/IL-5/GM-CSF receptor family
    • de Groot R.P., Coffer P.J., and Koenderman L. Regulation of proliferation, differentiation and survival by the IL-3/IL-5/GM-CSF receptor family. Cell. Signal. 10 (1998) 619-628
    • (1998) Cell. Signal. , vol.10 , pp. 619-628
    • de Groot, R.P.1    Coffer, P.J.2    Koenderman, L.3
  • 15
    • 0027215519 scopus 로고
    • Truncated erythropoietin receptor causes dominantly inherited benign human erythrocytosis
    • de la Chapelle A., Träskelin A.L., and Juvonen E. Truncated erythropoietin receptor causes dominantly inherited benign human erythrocytosis. Proc. Natl. Acad. Sci. U.S.A. 90 (1993) 4495-4499
    • (1993) Proc. Natl. Acad. Sci. U.S.A. , vol.90 , pp. 4495-4499
    • de la Chapelle, A.1    Träskelin, A.L.2    Juvonen, E.3
  • 16
    • 0030793449 scopus 로고    scopus 로고
    • Ligand-independent dimerization of the extracellular domain of the leptin receptor and determination of the stoichiometry of leptin binding
    • Devos R., Guisez Y., Van der Heyden J., White D.W., Kalai M., Fountoulakis M., and Plaetinck G. Ligand-independent dimerization of the extracellular domain of the leptin receptor and determination of the stoichiometry of leptin binding. J. Biol. Chem. 272 (1997) 18304-18310
    • (1997) J. Biol. Chem. , vol.272 , pp. 18304-18310
    • Devos, R.1    Guisez, Y.2    Van der Heyden, J.3    White, D.W.4    Kalai, M.5    Fountoulakis, M.6    Plaetinck, G.7
  • 18
    • 0030711559 scopus 로고    scopus 로고
    • Human pulmonary alveolar proteinosis associated with a defect in GM-CSF/IL-3/IL-5 receptor common beta chain expression
    • Dirksen U., Nishinakamura R., Groneck P., Hattenhorst U., Nogee L., Murray R., and Burdach S. Human pulmonary alveolar proteinosis associated with a defect in GM-CSF/IL-3/IL-5 receptor common beta chain expression. J. Clin. Invest. 100 (1997) 2211-2217
    • (1997) J. Clin. Invest. , vol.100 , pp. 2211-2217
    • Dirksen, U.1    Nishinakamura, R.2    Groneck, P.3    Hattenhorst, U.4    Nogee, L.5    Murray, R.6    Burdach, S.7
  • 19
    • 0037316938 scopus 로고    scopus 로고
    • Tissue microarray analysis of signal transducers and activators of transcription 3 (Stat3) and phospho-Stat3 (Tyr705) in node-negative breast cancer shows nuclear localization is associated with a better prognosis
    • Dolled-Filhart M., Camp R.L., Kowalski D.P., Smith B.L., and Rimm D.L. Tissue microarray analysis of signal transducers and activators of transcription 3 (Stat3) and phospho-Stat3 (Tyr705) in node-negative breast cancer shows nuclear localization is associated with a better prognosis. Clin. Cancer Res. 9 (2003) 594-600
    • (2003) Clin. Cancer Res. , vol.9 , pp. 594-600
    • Dolled-Filhart, M.1    Camp, R.L.2    Kowalski, D.P.3    Smith, B.L.4    Rimm, D.L.5
  • 20
    • 0029129034 scopus 로고
    • Mutations in the gene for the granulocyte colony-stimulating-factor receptor in patients with acute myeloid leukemia preceded by severe congenital neutropenia
    • Dong F., Brynes R.K., Tidow N., Welte K., Löwenberg B., and Touw I.P. Mutations in the gene for the granulocyte colony-stimulating-factor receptor in patients with acute myeloid leukemia preceded by severe congenital neutropenia. New Engl. J. Med. 333 (1995) 487-493
    • (1995) New Engl. J. Med. , vol.333 , pp. 487-493
    • Dong, F.1    Brynes, R.K.2    Tidow, N.3    Welte, K.4    Löwenberg, B.5    Touw, I.P.6
  • 22
    • 85047687240 scopus 로고    scopus 로고
    • Suppressor of cytokine-1 regulates acute inflammatory arthritis and T cell activation
    • Egan P.J., Lawlor K.E., Alexander W.S., and Wicks I.P. Suppressor of cytokine-1 regulates acute inflammatory arthritis and T cell activation. J. Clin. Res. 111 (2003) 915-924
    • (2003) J. Clin. Res. , vol.111 , pp. 915-924
    • Egan, P.J.1    Lawlor, K.E.2    Alexander, W.S.3    Wicks, I.P.4
  • 23
    • 13944258449 scopus 로고    scopus 로고
    • SOCS5 mRNA levels in peripheral blood mononuclear cells (PBMC): a potential bio-marker for monitoring response of uveitis patients to Daclizumab therapy
    • Egwuagu C.E., Yu C., Li Z., and Nussenblatt R.B. SOCS5 mRNA levels in peripheral blood mononuclear cells (PBMC): a potential bio-marker for monitoring response of uveitis patients to Daclizumab therapy. J. Autoimmun. 24 (2005) 39-46
    • (2005) J. Autoimmun. , vol.24 , pp. 39-46
    • Egwuagu, C.E.1    Yu, C.2    Li, Z.3    Nussenblatt, R.B.4
  • 26
    • 0035898315 scopus 로고    scopus 로고
    • Defective gp130-mediated signal transducer and activator of transcription (STAT) results in degenerative joint disease, gastrointestinal ulceration, and failure of uterine implantation
    • Ernst M., Inglese M., Waring P., Campbell I.K., Bao S., Clay F.J., Alexander W.S., Wicks I.P., Tarlinton D.M., Novak U., Heath J.K., and Dunn A.R. Defective gp130-mediated signal transducer and activator of transcription (STAT) results in degenerative joint disease, gastrointestinal ulceration, and failure of uterine implantation. J. Exp. Med. 194 (2001) 189-203
    • (2001) J. Exp. Med. , vol.194 , pp. 189-203
    • Ernst, M.1    Inglese, M.2    Waring, P.3    Campbell, I.K.4    Bao, S.5    Clay, F.J.6    Alexander, W.S.7    Wicks, I.P.8    Tarlinton, D.M.9    Novak, U.10    Heath, J.K.11    Dunn, A.R.12
  • 27
    • 5744222763 scopus 로고    scopus 로고
    • Thrombopoietin signaling in physiology and disease
    • Fishley B., and Alexander W.S. Thrombopoietin signaling in physiology and disease. Growth Factors 22 (2004) 151-155
    • (2004) Growth Factors , vol.22 , pp. 151-155
    • Fishley, B.1    Alexander, W.S.2
  • 28
    • 0035176107 scopus 로고    scopus 로고
    • Growth hormone signaling and its regulation: preventing too much of a good thing
    • Frank S.J. Growth hormone signaling and its regulation: preventing too much of a good thing. Growth Horm. IGF Res. 11 (2001) 201-212
    • (2001) Growth Horm. IGF Res. , vol.11 , pp. 201-212
    • Frank, S.J.1
  • 29
    • 18944379196 scopus 로고    scopus 로고
    • The many faces of IL-7: from lymphopoiesis to peripheral T cell maintenance
    • Fry T.J., and Mackall C.L. The many faces of IL-7: from lymphopoiesis to peripheral T cell maintenance. J. Immunol. 174 (2005) 6571-6576
    • (2005) J. Immunol. , vol.174 , pp. 6571-6576
    • Fry, T.J.1    Mackall, C.L.2
  • 31
    • 0035925887 scopus 로고    scopus 로고
    • Domains of the interleukin 2 receptor
    • Gaffen S.L. Domains of the interleukin 2 receptor. Cytokine 14 (2001) 63-77
    • (2001) Cytokine , vol.14 , pp. 63-77
    • Gaffen, S.L.1
  • 32
    • 0031965459 scopus 로고    scopus 로고
    • A truncated isoform of the human beta chain common to the receptors for granulocyte-macrophage colony-stimulating factor, interleukin-3 (IL-3), and IL-5 with increased mRNA expression in some patients with acute leukemia
    • Gale R.E., Freeburn R.W., Khwaja A., Chopra R., and Linch D.C. A truncated isoform of the human beta chain common to the receptors for granulocyte-macrophage colony-stimulating factor, interleukin-3 (IL-3), and IL-5 with increased mRNA expression in some patients with acute leukemia. Blood 91 (1998) 54-63
    • (1998) Blood , vol.91 , pp. 54-63
    • Gale, R.E.1    Freeburn, R.W.2    Khwaja, A.3    Chopra, R.4    Linch, D.C.5
  • 33
    • 33751226932 scopus 로고    scopus 로고
    • Multiple pathways contribute to the hyperproliferative responses from truncated granulocyte colony-stimulating factor receptors
    • Gits J., van Leeuwen D., Carroll H.P., Touw I.P., and Ward A.C. Multiple pathways contribute to the hyperproliferative responses from truncated granulocyte colony-stimulating factor receptors. Leukemia 20 (2007) 2111-2118
    • (2007) Leukemia , vol.20 , pp. 2111-2118
    • Gits, J.1    van Leeuwen, D.2    Carroll, H.P.3    Touw, I.P.4    Ward, A.C.5
  • 34
    • 0031803213 scopus 로고    scopus 로고
    • Differential constitutive activation between STAT-related proteins and MAP kinase in primary acute myelogenous leukaemia
    • Hayakawa F., Towatari M., Iida H., Wakao H., Kiyoi H., Naoe T., and Saito H. Differential constitutive activation between STAT-related proteins and MAP kinase in primary acute myelogenous leukaemia. Br. J. Haematol. 101 (1998) 521-528
    • (1998) Br. J. Haematol. , vol.101 , pp. 521-528
    • Hayakawa, F.1    Towatari, M.2    Iida, H.3    Wakao, H.4    Kiyoi, H.5    Naoe, T.6    Saito, H.7
  • 35
  • 36
    • 0028838012 scopus 로고
    • Dimerization of cell surface receptors in signal transduction
    • Heldin C.H. Dimerization of cell surface receptors in signal transduction. Cell 80 (1995) 213-223
    • (1995) Cell , vol.80 , pp. 213-223
    • Heldin, C.H.1
  • 38
    • 0028028415 scopus 로고
    • Evidence for the ligand-induced conversion from a dimer to a tetramer of the granulocyte colony-stimulating factor receptor
    • Hiraoka O., Anaguchi H., and Ota Y. Evidence for the ligand-induced conversion from a dimer to a tetramer of the granulocyte colony-stimulating factor receptor. FEBS Lett. 356 (1994) 255-260
    • (1994) FEBS Lett. , vol.356 , pp. 255-260
    • Hiraoka, O.1    Anaguchi, H.2    Ota, Y.3
  • 39
    • 0035694582 scopus 로고    scopus 로고
    • The N-terminal domain of Janus kinase 2 is required for Golgi processing and cell surface expression of erythropoietin receptor
    • Huang L.J., Constantinescu S.N., and Lodish H.F. The N-terminal domain of Janus kinase 2 is required for Golgi processing and cell surface expression of erythropoietin receptor. Mol. Cell 8 (2001) 1327-1338
    • (2001) Mol. Cell , vol.8 , pp. 1327-1338
    • Huang, L.J.1    Constantinescu, S.N.2    Lodish, H.F.3
  • 40
    • 0028864798 scopus 로고
    • A null mutation in the gene encoding a type I interferon receptor component eliminates antiproliferative and antiviral responses to interferons alpha and beta and alters macrophage responses
    • Hwang S.Y., Hertzog P.J., Holland K.A., Sumarsono S.H., Tymms M.J., Hamilton J.A., Whitty G., Bertoncello I., and Kola I. A null mutation in the gene encoding a type I interferon receptor component eliminates antiproliferative and antiviral responses to interferons alpha and beta and alters macrophage responses. Proc. Natl. Acad. Sci. U.S.A. 92 (1995) 11284-11288
    • (1995) Proc. Natl. Acad. Sci. U.S.A. , vol.92 , pp. 11284-11288
    • Hwang, S.Y.1    Hertzog, P.J.2    Holland, K.A.3    Sumarsono, S.H.4    Tymms, M.J.5    Hamilton, J.A.6    Whitty, G.7    Bertoncello, I.8    Kola, I.9
  • 47
    • 0028117163 scopus 로고
    • Cytokine signal transduction
    • Kishimoto T., Taga T., and Akira S. Cytokine signal transduction. Cell 76 (1994) 253-262
    • (1994) Cell , vol.76 , pp. 253-262
    • Kishimoto, T.1    Taga, T.2    Akira, S.3
  • 48
    • 2342444617 scopus 로고    scopus 로고
    • Full house: 12 receptors for 27 cytokines
    • Kotenko S.V., and Langer J.A. Full house: 12 receptors for 27 cytokines. Int. Immunopharmacol. 4 (2004) 593-608
    • (2004) Int. Immunopharmacol. , vol.4 , pp. 593-608
    • Kotenko, S.V.1    Langer, J.A.2
  • 49
    • 0034658583 scopus 로고    scopus 로고
    • Jak-Stat signal transduction pathway through the eyes of cytokine class II receptor complexes
    • Kotenko S.V., and Pestka S. Jak-Stat signal transduction pathway through the eyes of cytokine class II receptor complexes. Oncogene 19 (2000) 2557-2565
    • (2000) Oncogene , vol.19 , pp. 2557-2565
    • Kotenko, S.V.1    Pestka, S.2
  • 51
    • 9644295710 scopus 로고    scopus 로고
    • Cytokines and immunodeficiency diseases: critical roles of the gamma(c)-dependent cytokines interleukins 2, 4, 7, 9, 15, and 21, and their pathways
    • Kovanen P.E., and Leonard W.J. Cytokines and immunodeficiency diseases: critical roles of the gamma(c)-dependent cytokines interleukins 2, 4, 7, 9, 15, and 21, and their pathways. Immunol. Rev. 202 (2004) 67-83
    • (2004) Immunol. Rev. , vol.202 , pp. 67-83
    • Kovanen, P.E.1    Leonard, W.J.2
  • 58
    • 0028000668 scopus 로고
    • Mice lacking granulocyte colony-stimulating factor have chronic neutropenia, granulocyte and macrophage progenitor deficiency, and impaired neutrophil mobilization
    • Lieschke G.J., Grail D., Hodgson G., Metcalf D., Stanley E., Cheers C., Fowler K.J., Basu S., Zhan Y.F., and Dunn A.R. Mice lacking granulocyte colony-stimulating factor have chronic neutropenia, granulocyte and macrophage progenitor deficiency, and impaired neutrophil mobilization. Blood 84 (1994) 1737-1746
    • (1994) Blood , vol.84 , pp. 1737-1746
    • Lieschke, G.J.1    Grail, D.2    Hodgson, G.3    Metcalf, D.4    Stanley, E.5    Cheers, C.6    Fowler, K.J.7    Basu, S.8    Zhan, Y.F.9    Dunn, A.R.10
  • 59
    • 0034658153 scopus 로고    scopus 로고
    • STAT in the pathogenesis and treatment of leukemias
    • Lin T.S., Mahajan S., and Frank D.A. STAT in the pathogenesis and treatment of leukemias. Oncogene 19 (2000) 2496-2504
    • (2000) Oncogene , vol.19 , pp. 2496-2504
    • Lin, T.S.1    Mahajan, S.2    Frank, D.A.3
  • 62
    • 0032809058 scopus 로고    scopus 로고
    • Interleukin-3 in hematology and oncology: current state of knowledge and future directions
    • Mangi M.H., and Newland A.C. Interleukin-3 in hematology and oncology: current state of knowledge and future directions. Cytokines Cell. Mol. Ther. 5 (1999) 87-95
    • (1999) Cytokines Cell. Mol. Ther. , vol.5 , pp. 87-95
    • Mangi, M.H.1    Newland, A.C.2
  • 63
    • 0030956715 scopus 로고    scopus 로고
    • CIS, a cytokine inducible SH2 protein, is a target of the JAK-STAT5 pathway and modulates STAT5 activation
    • Matsumoto A., Masuhara M., Mitsui K., Yokouchi M., Ohtsubo M., Misawa H., Miyajima A., and Yoshimura A. CIS, a cytokine inducible SH2 protein, is a target of the JAK-STAT5 pathway and modulates STAT5 activation. Blood 89 (1997) 3148-3154
    • (1997) Blood , vol.89 , pp. 3148-3154
    • Matsumoto, A.1    Masuhara, M.2    Mitsui, K.3    Yokouchi, M.4    Ohtsubo, M.5    Misawa, H.6    Miyajima, A.7    Yoshimura, A.8
  • 65
    • 0037119351 scopus 로고    scopus 로고
    • Cytokine and cytokine receptor pleiotropy and redundancy
    • Ozaki K., and Leonard W.J. Cytokine and cytokine receptor pleiotropy and redundancy. J. Biol. Chem. 277 (2002) 29355-29358
    • (2002) J. Biol. Chem. , vol.277 , pp. 29355-29358
    • Ozaki, K.1    Leonard, W.J.2
  • 66
    • 26844503986 scopus 로고    scopus 로고
    • The control of allergic conjunctivitis by suppressor of cytokine (SOCS)3 and SOCS5 in a murine model
    • Ozaki A., Seki Y., Fukushima A., and Kubo M. The control of allergic conjunctivitis by suppressor of cytokine (SOCS)3 and SOCS5 in a murine model. J. Immunol. 175 (2005) 5489-5497
    • (2005) J. Immunol. , vol.175 , pp. 5489-5497
    • Ozaki, A.1    Seki, Y.2    Fukushima, A.3    Kubo, M.4
  • 68
    • 0030637626 scopus 로고    scopus 로고
    • Interleukin-4: signaling mechanisms and control of T cell differentiation
    • Paul W.E. Interleukin-4: signaling mechanisms and control of T cell differentiation. Ciba Found. Symp. 204 (1997) 208-216
    • (1997) Ciba Found. Symp. , vol.204 , pp. 208-216
    • Paul, W.E.1
  • 72
    • 0031740732 scopus 로고    scopus 로고
    • Defective IL7R expression in T-B + NK + severe combined immunodeficiency
    • Puel A., Ziegler S.F., Buckley R.H., and Leonard W.J. Defective IL7R expression in T-B + NK + severe combined immunodeficiency. Nat. Genet. 20 (1998) 394-397
    • (1998) Nat. Genet. , vol.20 , pp. 394-397
    • Puel, A.1    Ziegler, S.F.2    Buckley, R.H.3    Leonard, W.J.4
  • 73
    • 0033548048 scopus 로고    scopus 로고
    • Erythropoietin receptor activation by a ligand-induced conformation change
    • Remy I., Wilson I.A., and Michnick S.W. Erythropoietin receptor activation by a ligand-induced conformation change. Science 283 (1999) 990-993
    • (1999) Science , vol.283 , pp. 990-993
    • Remy, I.1    Wilson, I.A.2    Michnick, S.W.3
  • 74
    • 0141720769 scopus 로고    scopus 로고
    • Class II cytokine receptors and their ligands: key antiviral and inflammatory modulators
    • Renauld J.C. Class II cytokine receptors and their ligands: key antiviral and inflammatory modulators. Nat. Rev. Immunol. 3 (2003) 667-676
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 667-676
    • Renauld, J.C.1
  • 75
    • 14744299761 scopus 로고    scopus 로고
    • Turning cells red: signal transduction mediated by erythropoietin
    • Richmond T.D., Chohan M., and Barber D.L. Turning cells red: signal transduction mediated by erythropoietin. Trends Cell Biol. 15 (2005) 146-155
    • (2005) Trends Cell Biol. , vol.15 , pp. 146-155
    • Richmond, T.D.1    Chohan, M.2    Barber, D.L.3
  • 76
    • 0032885128 scopus 로고    scopus 로고
    • Interleukin-5 and the regulation of eosinophil production
    • Roboz G.J., and Rafii S. Interleukin-5 and the regulation of eosinophil production. Curr. Opin. Hematol. 6 (1999) 164-168
    • (1999) Curr. Opin. Hematol. , vol.6 , pp. 164-168
    • Roboz, G.J.1    Rafii, S.2
  • 77
    • 0036746091 scopus 로고    scopus 로고
    • IL-13 signal transduction in human monocytes: phosphorylation of receptor components, association with Jaks, and phosphorylation/activation of Stats
    • Roy B., Bhattacharjee A., Xu B., Ford D., Maizel A.L., and Cathcart M.K. IL-13 signal transduction in human monocytes: phosphorylation of receptor components, association with Jaks, and phosphorylation/activation of Stats. J. Leukoc. Biol. 72 (2002) 580-589
    • (2002) J. Leukoc. Biol. , vol.72 , pp. 580-589
    • Roy, B.1    Bhattacharjee, A.2    Xu, B.3    Ford, D.4    Maizel, A.L.5    Cathcart, M.K.6
  • 78
    • 0034012330 scopus 로고    scopus 로고
    • Regulation of the Jak2 tyrosine kinase by its pseudokinase domain
    • Saharinen P., Takaluoma K., and Silvennoinen O. Regulation of the Jak2 tyrosine kinase by its pseudokinase domain. Mol. Cell. Biol. 20 (2000) 3387-3395
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 3387-3395
    • Saharinen, P.1    Takaluoma, K.2    Silvennoinen, O.3
  • 79
    • 0033135134 scopus 로고    scopus 로고
    • Constitutive activation of an epithelial signal transducer and activator of transcription (STAT) pathway in asthma
    • Sampath D., Castro M., Look D.C., and Holtzman M.J. Constitutive activation of an epithelial signal transducer and activator of transcription (STAT) pathway in asthma. J. Clin. Invest. 103 (1999) 1353-1361
    • (1999) J. Clin. Invest. , vol.103 , pp. 1353-1361
    • Sampath, D.1    Castro, M.2    Look, D.C.3    Holtzman, M.J.4
  • 81
    • 1942518231 scopus 로고    scopus 로고
    • Hepatitis C virus NS5A mediated STAT3 activation requires co-operation of Jak1 kinase
    • Sarcar B., Ghosh A.K., Steele R., Ray R., and Ray R.B. Hepatitis C virus NS5A mediated STAT3 activation requires co-operation of Jak1 kinase. Virology 322 (2004) 51-60
    • (2004) Virology , vol.322 , pp. 51-60
    • Sarcar, B.1    Ghosh, A.K.2    Steele, R.3    Ray, R.4    Ray, R.B.5
  • 82
    • 0028348567 scopus 로고
    • Multimeric cytokine receptors: common versus specific functions
    • Sato N., and Miyajima A. Multimeric cytokine receptors: common versus specific functions. Curr. Opin. Cell Biol. 6 (1994) 174-179
    • (1994) Curr. Opin. Cell Biol. , vol.6 , pp. 174-179
    • Sato, N.1    Miyajima, A.2
  • 85
    • 0029810923 scopus 로고    scopus 로고
    • Constitutive activation of STAT5 by the BCR-ABL oncogene in chronic myelogenous leukemia
    • Shuai K., Halpern J., ten Hoeve J., Rao X., and Sawyers C.L. Constitutive activation of STAT5 by the BCR-ABL oncogene in chronic myelogenous leukemia. Oncogene 13 (1996) 247-254
    • (1996) Oncogene , vol.13 , pp. 247-254
    • Shuai, K.1    Halpern, J.2    ten Hoeve, J.3    Rao, X.4    Sawyers, C.L.5
  • 87
    • 0037079728 scopus 로고    scopus 로고
    • Signal transducer and activator of transcription 6 is frequently activated in Hodgkin and Reed-Sternberg cells of Hodgkin lymphoma
    • Skinnider B.F., Elia A.J., Gascoyne R.D., Patterson B., Trumper L., Kapp U., and Mak T.W. Signal transducer and activator of transcription 6 is frequently activated in Hodgkin and Reed-Sternberg cells of Hodgkin lymphoma. Blood 99 (2002) 618-626
    • (2002) Blood , vol.99 , pp. 618-626
    • Skinnider, B.F.1    Elia, A.J.2    Gascoyne, R.D.3    Patterson, B.4    Trumper, L.5    Kapp, U.6    Mak, T.W.7
  • 88
    • 21344440357 scopus 로고    scopus 로고
    • The JAK2 V617F activating tyrosine kinase mutation is an infrequent event in both "atypical" myeloproliferative disorders and myelodysplastic syndromes
    • Steensma D.P., Dewald G.W., Lasho T.L., Powell H.L., McClure R.F., Levine R.L., Gilliland D.G., and Tefferi A. The JAK2 V617F activating tyrosine kinase mutation is an infrequent event in both "atypical" myeloproliferative disorders and myelodysplastic syndromes. Blood 106 (2005) 1207-1209
    • (2005) Blood , vol.106 , pp. 1207-1209
    • Steensma, D.P.1    Dewald, G.W.2    Lasho, T.L.3    Powell, H.L.4    McClure, R.F.5    Levine, R.L.6    Gilliland, D.G.7    Tefferi, A.8
  • 89
    • 25844464922 scopus 로고    scopus 로고
    • Induction of suppressors of cytokine (SOCS) in the retina during experimental autoimmune uveitis (EAU): potential neuroprotective role of SOCS proteins
    • Takase H., Yu C.R., Liu X., Fujimoto C., Gery I., and Egwuagu C.E. Induction of suppressors of cytokine (SOCS) in the retina during experimental autoimmune uveitis (EAU): potential neuroprotective role of SOCS proteins. J. Neuroimmunol. 168 (2005) 118-127
    • (2005) J. Neuroimmunol. , vol.168 , pp. 118-127
    • Takase, H.1    Yu, C.R.2    Liu, X.3    Fujimoto, C.4    Gery, I.5    Egwuagu, C.E.6
  • 93
    • 0030221525 scopus 로고    scopus 로고
    • Severe congenital neutropenia terminating in acute myeloid leukemia: disease progression associated with mutations in the granulocyte-colony stimulating factor receptor gene
    • Touw I.P., and Dong F. Severe congenital neutropenia terminating in acute myeloid leukemia: disease progression associated with mutations in the granulocyte-colony stimulating factor receptor gene. Leuk. Res. 20 (1996) 629-631
    • (1996) Leuk. Res. , vol.20 , pp. 629-631
    • Touw, I.P.1    Dong, F.2
  • 94
    • 0028944489 scopus 로고
    • Alpha and beta interferons and their receptor and their friends and relations
    • Uze G., Lutfalla G., and Mogensen K.E. Alpha and beta interferons and their receptor and their friends and relations. J. Interferon Cytokine Res. 15 (1995) 3-26
    • (1995) J. Interferon Cytokine Res. , vol.15 , pp. 3-26
    • Uze, G.1    Lutfalla, G.2    Mogensen, K.E.3
  • 95
    • 33846921639 scopus 로고    scopus 로고
    • The role of the granulocyte colony-stimulating factor receptor (G-CSF-R) in disease
    • Ward A.C. The role of the granulocyte colony-stimulating factor receptor (G-CSF-R) in disease. Front. Biosci. 12 (2007) 608-618
    • (2007) Front. Biosci. , vol.12 , pp. 608-618
    • Ward, A.C.1
  • 96
    • 0033575794 scopus 로고    scopus 로고
    • Novel point mutation in the extracellular domain of the granulocyte colony-stimulating factor (G-CSF) receptor in a case of severe congenital neutropenia hyporesponsive to G-CSF treatment
    • Ward A.C., van Aesch Y.M., Gits J., Schelen A.M., de Koning J.P., van Leeuwen D., Freedman M.H., and Touw I.P. Novel point mutation in the extracellular domain of the granulocyte colony-stimulating factor (G-CSF) receptor in a case of severe congenital neutropenia hyporesponsive to G-CSF treatment. J. Exp. Med. 190 (1999) 497-507
    • (1999) J. Exp. Med. , vol.190 , pp. 497-507
    • Ward, A.C.1    van Aesch, Y.M.2    Gits, J.3    Schelen, A.M.4    de Koning, J.P.5    van Leeuwen, D.6    Freedman, M.H.7    Touw, I.P.8
  • 97
    • 0033976059 scopus 로고    scopus 로고
    • The Jak-Stat pathway in normal and perturbed hematopoiesis
    • Ward A.C., Touw I., and Yoshimura A. The Jak-Stat pathway in normal and perturbed hematopoiesis. Blood 95 (2000) 19-29
    • (2000) Blood , vol.95 , pp. 19-29
    • Ward, A.C.1    Touw, I.2    Yoshimura, A.3
  • 100
    • 0029784886 scopus 로고    scopus 로고
    • Constitutive activation of STAT proteins in primary lymphoid and myeloid leukemia cells and in Epstein-Barr virus (EBV)-related lymphoma cell lines
    • Weber-Nordt R.M., Egen C., Wehinger J., Ludwig W., Gouilleux-Gruart V., Mertelsmann R., and Finke J. Constitutive activation of STAT proteins in primary lymphoid and myeloid leukemia cells and in Epstein-Barr virus (EBV)-related lymphoma cell lines. Blood 88 (1996) 809-816
    • (1996) Blood , vol.88 , pp. 809-816
    • Weber-Nordt, R.M.1    Egen, C.2    Wehinger, J.3    Ludwig, W.4    Gouilleux-Gruart, V.5    Mertelsmann, R.6    Finke, J.7
  • 102
    • 0037293234 scopus 로고    scopus 로고
    • Measles virus suppresses interferon-alpha pathway: suppression of Jak1 phosphorylation and association of viral accessory proteins, C and V, with interferon-alpha receptor complex
    • Yokota S., Saito H., Kubota T., Yokosawa N., Amano K., and Fujii N. Measles virus suppresses interferon-alpha pathway: suppression of Jak1 phosphorylation and association of viral accessory proteins, C and V, with interferon-alpha receptor complex. Virology 306 (2003) 135-146
    • (2003) Virology , vol.306 , pp. 135-146
    • Yokota, S.1    Saito, H.2    Kubota, T.3    Yokosawa, N.4    Amano, K.5    Fujii, N.6
  • 105
    • 0029011115 scopus 로고
    • The amino-terminal portion of the JAK2 protein kinase is necessary for binding and phosphorylation of the granulocyte-macrophage colony-stimulating factor receptor beta c chain
    • Zhao Y., Wagner F., Frank S.J., and Kraft A.S. The amino-terminal portion of the JAK2 protein kinase is necessary for binding and phosphorylation of the granulocyte-macrophage colony-stimulating factor receptor beta c chain. J. Biol. Chem. 270 (1995) 13814-13818
    • (1995) J. Biol. Chem. , vol.270 , pp. 13814-13818
    • Zhao, Y.1    Wagner, F.2    Frank, S.J.3    Kraft, A.S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.