-
1
-
-
33845881411
-
Mechanisms linking obesity to insulin resistance and type 2 diabetes
-
COI: 1:CAS:528:DC%2BD28XhtlShtrzP, PID: 17167471
-
Kahn SE, Hull RL, Utzschneider KM. Mechanisms linking obesity to insulin resistance and type 2 diabetes. Nature. 2006;444(7121):840–6. doi:10.1038/nature05482.
-
(2006)
Nature
, vol.444
, Issue.7121
, pp. 840-846
-
-
Kahn, S.E.1
Hull, R.L.2
Utzschneider, K.M.3
-
2
-
-
52949145686
-
Management of obesity in adults: European clinical practice guidelines
-
PID: 20054170
-
Tsigos C, Hainer V, Basdevant A, et al. Management of obesity in adults: European clinical practice guidelines. Obes Facts. 2008;1(2):106–16. doi:10.1159/000126822.
-
(2008)
Obes Facts
, vol.1
, Issue.2
, pp. 106-116
-
-
Tsigos, C.1
Hainer, V.2
Basdevant, A.3
-
3
-
-
79960895140
-
Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile
-
COI: 1:CAS:528:DC%2BC3MXotV2itrY%3D, PID: 21706003
-
Kilpelainen TO, Zillikens MC, Stancakova A, et al. Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile. Nat Genet. 2011;43(8):753–60. doi:10.1038/ng.866.
-
(2011)
Nat Genet
, vol.43
, Issue.8
, pp. 753-760
-
-
Kilpelainen, T.O.1
Zillikens, M.C.2
Stancakova, A.3
-
4
-
-
84863684047
-
Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women
-
COI: 1:CAS:528:DC%2BC38XnslOlt70%3D, PID: 22589738
-
Fox CS, Liu Y, White CC, et al. Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women. PLoS Genet. 2012;8(5):e1002695. doi:10.1371/journal.pgen.1002695.
-
(2012)
PLoS Genet
, vol.8
, Issue.5
, pp. e1002695
-
-
Fox, C.S.1
Liu, Y.2
White, C.C.3
-
5
-
-
34347351228
-
Abdominal visceral and subcutaneous adipose tissue compartments: association with metabolic risk factors in the Framingham Heart Study
-
PID: 17576866
-
Fox CS, Massaro JM, Hoffmann U, et al. Abdominal visceral and subcutaneous adipose tissue compartments: association with metabolic risk factors in the Framingham Heart Study. Circulation. 2007;116(1):39–48. doi:10.1161/CIRCULATIONAHA.106.675355.
-
(2007)
Circulation
, vol.116
, Issue.1
, pp. 39-48
-
-
Fox, C.S.1
Massaro, J.M.2
Hoffmann, U.3
-
6
-
-
80052895204
-
A genome-wide association study reveals a quantitative trait locus of adiponectin on CDH13 that predicts cardiometabolic outcomes
-
COI: 1:CAS:528:DC%2BC3MXhtFymsbbF, PID: 21771975
-
Chung CM, Lin TH, Chen JW, et al. A genome-wide association study reveals a quantitative trait locus of adiponectin on CDH13 that predicts cardiometabolic outcomes. Diabetes. 2011;60(9):2417–23. doi:10.2337/db10-1321.
-
(2011)
Diabetes
, vol.60
, Issue.9
, pp. 2417-2423
-
-
Chung, C.M.1
Lin, T.H.2
Chen, J.W.3
-
7
-
-
84859238629
-
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals
-
COI: 1:CAS:528:DC%2BC38XlsFaltbs%3D, PID: 22479202
-
Dastani Z, Hivert MF, Timpson N, et al. Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet. 2012;8(3):e1002607. doi:10.1371/journal.pgen.1002607.
-
(2012)
PLoS Genet
, vol.8
, Issue.3
, pp. e1002607
-
-
Dastani, Z.1
Hivert, M.F.2
Timpson, N.3
-
8
-
-
74749102353
-
Clear detection of ADIPOQ locus as the major gene for plasma adiponectin: results of genome-wide association analyses including 4659 European individuals
-
COI: 1:CAS:528:DC%2BC3cXhtlyqs74%3D, PID: 20018283
-
Heid IM, Henneman P, Hicks A, et al. Clear detection of ADIPOQ locus as the major gene for plasma adiponectin: results of genome-wide association analyses including 4659 European individuals. Atherosclerosis. 2010;208(2):412–20. doi:10.1016/j.atherosclerosis.2009.11.035.
-
(2010)
Atherosclerosis
, vol.208
, Issue.2
, pp. 412-420
-
-
Heid, I.M.1
Henneman, P.2
Hicks, A.3
-
9
-
-
77957750180
-
Adiponectin concentrations: a genome-wide association study
-
COI: 1:CAS:528:DC%2BC3cXht1CgtrbP, PID: 20887962
-
Jee SH, Sull JW, Lee JE, et al. Adiponectin concentrations: a genome-wide association study. Am J Hum Genet. 2010;87(4):545–52. doi:10.1016/j.ajhg.2010.09.004.
-
(2010)
Am J Hum Genet
, vol.87
, Issue.4
, pp. 545-552
-
-
Jee, S.H.1
Sull, J.W.2
Lee, J.E.3
-
10
-
-
84857533640
-
CDH13 gene coding T-cadherin influences variations in plasma adiponectin levels in the Japanese population
-
COI: 1:CAS:528:DC%2BC38XmtlGhsw%3D%3D, PID: 22065538
-
Morisaki H, Yamanaka I, Iwai N, et al. CDH13 gene coding T-cadherin influences variations in plasma adiponectin levels in the Japanese population. Hum Mutat. 2012;33(2):402–10. doi:10.1002/humu.21652.
-
(2012)
Hum Mutat
, vol.33
, Issue.2
, pp. 402-410
-
-
Morisaki, H.1
Yamanaka, I.2
Iwai, N.3
-
11
-
-
84893008349
-
A meta-analysis of genome-wide association studies for adiponectin levels in East Asians identifies a novel locus near WDR11-FGFR2
-
COI: 1:CAS:528:DC%2BC2cXht1Ogt7k%3D, PID: 24105470
-
Wu Y, Gao H, Li H, et al. A meta-analysis of genome-wide association studies for adiponectin levels in East Asians identifies a novel locus near WDR11-FGFR2. Hum Mol Genet. 2014;23(4):1108–19. doi:10.1093/hmg/ddt488.
-
(2014)
Hum Mol Genet
, vol.23
, Issue.4
, pp. 1108-1119
-
-
Wu, Y.1
Gao, H.2
Li, H.3
-
12
-
-
78649476050
-
Genome-wide association study for adiponectin levels in Filipino women identifies CDH13 and a novel uncommon haplotype at KNG1-ADIPOQ
-
COI: 1:CAS:528:DC%2BC3cXhsVyhsrzE, PID: 20876611
-
Wu Y, Li Y, Lange EM, et al. Genome-wide association study for adiponectin levels in Filipino women identifies CDH13 and a novel uncommon haplotype at KNG1-ADIPOQ. Hum Mol Genet. 2010;19(24):4955–64. doi:10.1093/hmg/ddq423.
-
(2010)
Hum Mol Genet
, vol.19
, Issue.24
, pp. 4955-4964
-
-
Wu, Y.1
Li, Y.2
Lange, E.M.3
-
13
-
-
74249100913
-
A genome-wide association study reveals variants in ARL15 that influence adiponectin levels
-
PID: 20011104
-
Richards JB, Waterworth D, O'Rahilly S, et al. A genome-wide association study reveals variants in ARL15 that influence adiponectin levels. PLoS Genet. 2009;5(12):e1000768. doi:10.1371/journal.pgen.1000768.
-
(2009)
PLoS Genet
, vol.5
, Issue.12
, pp. e1000768
-
-
Richards, J.B.1
Waterworth, D.2
O'Rahilly, S.3
-
14
-
-
84863689970
-
Genome-wide association of pericardial fat identifies a unique locus for ectopic fat
-
COI: 1:CAS:528:DC%2BC38XnslOltrc%3D, PID: 22589742
-
Fox CS, White CC, Lohman K, et al. Genome-wide association of pericardial fat identifies a unique locus for ectopic fat. PLoS Genet. 2012;8(5):e1002705. doi:10.1371/journal.pgen.1002705.
-
(2012)
PLoS Genet
, vol.8
, Issue.5
, pp. e1002705
-
-
Fox, C.S.1
White, C.C.2
Lohman, K.3
-
15
-
-
79953745343
-
Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits
-
COI: 1:CAS:528:DC%2BC3MXjslKlsL4%3D, PID: 21423719
-
Speliotes EK, Yerges-Armstrong LM, Wu J, et al. Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits. PLoS Genet. 2011;7(3):e1001324. doi:10.1371/journal.pgen.1001324.
-
(2011)
PLoS Genet
, vol.7
, Issue.3
, pp. e1001324
-
-
Speliotes, E.K.1
Yerges-Armstrong, L.M.2
Wu, J.3
-
17
-
-
0030989520
-
Body fat distribution and risk of non-insulin-dependent diabetes mellitus in women. The Nurses’ Health Study
-
COI: 1:STN:280:DyaK2s3lt1Ohsg%3D%3D, PID: 9098178
-
Carey VJ, Walters EE, Colditz GA, et al. Body fat distribution and risk of non-insulin-dependent diabetes mellitus in women. The Nurses’ Health Study. Am J Epidemiol. 1997;145(7):614–9.
-
(1997)
Am J Epidemiol
, vol.145
, Issue.7
, pp. 614-619
-
-
Carey, V.J.1
Walters, E.E.2
Colditz, G.A.3
-
18
-
-
15744387573
-
Comparison of abdominal adiposity and overall obesity in predicting risk of type 2 diabetes among men
-
COI: 1:CAS:528:DC%2BD2MXis1Sktbo%3D, PID: 15755822
-
Wang Y, Rimm EB, Stampfer MJ, et al. Comparison of abdominal adiposity and overall obesity in predicting risk of type 2 diabetes among men. Am J Clin Nutr. 2005;81(3):555–63.
-
(2005)
Am J Clin Nutr
, vol.81
, Issue.3
, pp. 555-563
-
-
Wang, Y.1
Rimm, E.B.2
Stampfer, M.J.3
-
19
-
-
84968822322
-
-
Belgium: International Diabetes Federation
-
International Diabetes Federation. IDF Diabetes Atlas update poster teB, Belgium: International Diabetes Federation, 2014. http://www.idf.org/diabetesatlas.
-
(2014)
IDF Diabetes Atlas update poster teB
-
-
-
20
-
-
0033645239
-
Parental transmission of type 2 diabetes: the Framingham Offspring Study
-
COI: 1:CAS:528:DC%2BD3cXos1ejsbw%3D, PID: 11118026
-
Meigs JB, Cupples LA, Wilson PW. Parental transmission of type 2 diabetes: the Framingham Offspring Study. Diabetes. 2000;49(12):2201–7.
-
(2000)
Diabetes
, vol.49
, Issue.12
, pp. 2201-2207
-
-
Meigs, J.B.1
Cupples, L.A.2
Wilson, P.W.3
-
21
-
-
0032953097
-
Heritability of type II (non-insulin-dependent) diabetes mellitus and abnormal glucose tolerance—a population-based twin study
-
COI: 1:CAS:528:DyaK1MXhtFajsbk%3D, PID: 10064092
-
Poulsen P, Kyvik KO, Vaag A, et al. Heritability of type II (non-insulin-dependent) diabetes mellitus and abnormal glucose tolerance—a population-based twin study. Diabetologia. 1999;42(2):139–45.
-
(1999)
Diabetologia
, vol.42
, Issue.2
, pp. 139-145
-
-
Poulsen, P.1
Kyvik, K.O.2
Vaag, A.3
-
22
-
-
0022589555
-
A twin study of human obesity
-
COI: 1:STN:280:DyaL283isl2lsg%3D%3D, PID: 3712713
-
Stunkard AJ, Foch TT, Hrubec Z. A twin study of human obesity. JAMA. 1986;256(1):51–4.
-
(1986)
JAMA
, vol.256
, Issue.1
, pp. 51-54
-
-
Stunkard, A.J.1
Foch, T.T.2
Hrubec, Z.3
-
23
-
-
40049088818
-
Immigrants from the Middle-East have a different form of type 2 diabetes compared with Swedish patients
-
COI: 1:CAS:528:DC%2BD1cXkvFOksLg%3D, PID: 18307458
-
Glans F, Elgzyri T, Shaat N, et al. Immigrants from the Middle-East have a different form of type 2 diabetes compared with Swedish patients. Diabet Med. 2008;25(3):303–7. doi:10.1111/j.1464-5491.2007.02366.x.
-
(2008)
Diabet Med
, vol.25
, Issue.3
, pp. 303-307
-
-
Glans, F.1
Elgzyri, T.2
Shaat, N.3
-
24
-
-
0030843960
-
Genetic and environmental factors in relative body weight and human adiposity
-
COI: 1:STN:280:DyaK1c7otVSruw%3D%3D, PID: 9519560
-
Maes HH, Neale MC, Eaves LJ. Genetic and environmental factors in relative body weight and human adiposity. Behav Genet. 1997;27(4):325–51.
-
(1997)
Behav Genet
, vol.27
, Issue.4
, pp. 325-351
-
-
Maes, H.H.1
Neale, M.C.2
Eaves, L.J.3
-
25
-
-
55649114631
-
Sex-specific genetic effects influence variation in body composition
-
COI: 1:CAS:528:DC%2BD1cXhtlCjs7%2FN, PID: 18839131
-
Zillikens MC, Yazdanpanah M, Pardo LM, et al. Sex-specific genetic effects influence variation in body composition. Diabetologia. 2008;51(12):2233–41. doi:10.1007/s00125-008-1163-0.
-
(2008)
Diabetologia
, vol.51
, Issue.12
, pp. 2233-2241
-
-
Zillikens, M.C.1
Yazdanpanah, M.2
Pardo, L.M.3
-
26
-
-
80054707972
-
Heritability and familiality of type 2 diabetes and related quantitative traits in the Botnia Study
-
COI: 1:CAS:528:DC%2BC3MXht12js7rM, PID: 21826484
-
Almgren P, Lehtovirta M, Isomaa B, et al. Heritability and familiality of type 2 diabetes and related quantitative traits in the Botnia Study. Diabetologia. 2011;54(11):2811–9. doi:10.1007/s00125-011-2267-5.
-
(2011)
Diabetologia
, vol.54
, Issue.11
, pp. 2811-2819
-
-
Almgren, P.1
Lehtovirta, M.2
Isomaa, B.3
-
27
-
-
84899676296
-
Impact of the gut microbiota on the development of obesity and type 2 diabetes mellitus
-
PID: 24808896
-
Moreno-Indias I, Cardona F, Tinahones FJ, et al. Impact of the gut microbiota on the development of obesity and type 2 diabetes mellitus. Front Microbiol. 2014;5:190. doi:10.3389/fmicb.2014.00190.
-
(2014)
Front Microbiol
, vol.5
, pp. 190
-
-
Moreno-Indias, I.1
Cardona, F.2
Tinahones, F.J.3
-
28
-
-
64549104842
-
The use of animal models in the study of diabetes mellitus
-
COI: 1:CAS:528:DC%2BD1MXltFyisr8%3D, PID: 19414410
-
Chatzigeorgiou A, Halapas A, Kalafatakis K, et al. The use of animal models in the study of diabetes mellitus. In Vivo. 2009;23(2):245–58.
-
(2009)
In Vivo
, vol.23
, Issue.2
, pp. 245-258
-
-
Chatzigeorgiou, A.1
Halapas, A.2
Kalafatakis, K.3
-
29
-
-
0032751471
-
Epigenetic inheritance at the agouti locus in the mouse
-
COI: 1:CAS:528:DyaK1MXnt1Gns7w%3D, PID: 10545949
-
Morgan HD, Sutherland HG, Martin DI, et al. Epigenetic inheritance at the agouti locus in the mouse. Nat Genet. 1999;23(3):314–8. doi:10.1038/15490.
-
(1999)
Nat Genet
, vol.23
, Issue.3
, pp. 314-318
-
-
Morgan, H.D.1
Sutherland, H.G.2
Martin, D.I.3
-
30
-
-
52449123919
-
Mutations in ligands and receptors of the leptin-melanocortin pathway that lead to obesity
-
COI: 1:CAS:528:DC%2BD1cXhtFemsbnK, PID: 18779842
-
Farooqi IS, O'Rahilly S. Mutations in ligands and receptors of the leptin-melanocortin pathway that lead to obesity. Nat Clin Pract Endocrinol Metab. 2008;4(10):569–77. doi:10.1038/ncpendmet0966.
-
(2008)
Nat Clin Pract Endocrinol Metab
, vol.4
, Issue.10
, pp. 569-577
-
-
Farooqi, I.S.1
O'Rahilly, S.2
-
31
-
-
0343953074
-
Dominant and recessive inheritance of morbid obesity associated with melanocortin 4 receptor deficiency
-
COI: 1:CAS:528:DC%2BD3cXkvFWgs74%3D, PID: 10903343
-
Farooqi IS, Yeo GS, Keogh JM, et al. Dominant and recessive inheritance of morbid obesity associated with melanocortin 4 receptor deficiency. J Clin Invest. 2000;106(2):271–9. doi:10.1172/JCI9397.
-
(2000)
J Clin Invest
, vol.106
, Issue.2
, pp. 271-279
-
-
Farooqi, I.S.1
Yeo, G.S.2
Keogh, J.M.3
-
32
-
-
84896495361
-
Many faces of monogenic diabetes
-
PID: 24843749
-
Schwitzgebel VM. Many faces of monogenic diabetes. J Diabetes Investig. 2014;5(2):121–33. doi:10.1111/jdi.12197.
-
(2014)
J Diabetes Investig
, vol.5
, Issue.2
, pp. 121-133
-
-
Schwitzgebel, V.M.1
-
33
-
-
77954407332
-
Genomewide association studies and assessment of the risk of disease
-
COI: 1:CAS:528:DC%2BC3cXptFWmt7w%3D, PID: 20647212
-
Manolio TA. Genomewide association studies and assessment of the risk of disease. N Engl J Med. 2010;363(2):166–76. doi:10.1056/NEJMra0905980.
-
(2010)
N Engl J Med
, vol.363
, Issue.2
, pp. 166-176
-
-
Manolio, T.A.1
-
34
-
-
75749086085
-
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
-
COI: 1:CAS:528:DC%2BC3cXntVCqsw%3D%3D, PID: 20081858
-
Dupuis J, Langenberg C, Prokopenko I, et al. New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet. 2010;42(2):105–16. doi:10.1038/ng.520.
-
(2010)
Nat Genet
, vol.42
, Issue.2
, pp. 105-116
-
-
Dupuis, J.1
Langenberg, C.2
Prokopenko, I.3
-
35
-
-
72449122779
-
Parental origin of sequence variants associated with complex diseases
-
COI: 1:CAS:528:DC%2BD1MXhsFOhtbvJ, PID: 20016592
-
Kong A, Steinthorsdottir V, Masson G, et al. Parental origin of sequence variants associated with complex diseases. Nature. 2009;462(7275):868–74. doi:10.1038/nature08625.
-
(2009)
Nature
, vol.462
, Issue.7275
, pp. 868-874
-
-
Kong, A.1
Steinthorsdottir, V.2
Masson, G.3
-
36
-
-
84868337361
-
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes
-
COI: 1:CAS:528:DC%2BC38XhtFOgsLfP, PID: 22885922, This is a large GWAS of mainly European cases and controls identifying 10 additional loci associated with T2D susceptibility
-
Morris AP, Voight BF, Teslovich TM, et al. Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nat Genet. 2012;44(9):981–90. doi:10.1038/ng.2383. This is a large GWAS of mainly European cases and controls identifying 10 additional loci associated with T2D susceptibility.
-
(2012)
Nat Genet
, vol.44
, Issue.9
, pp. 981-990
-
-
Morris, A.P.1
Voight, B.F.2
Teslovich, T.M.3
-
37
-
-
77954143522
-
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis
-
COI: 1:CAS:528:DC%2BC3cXnvFykt70%3D, PID: 20581827
-
Voight BF, Scott LJ, Steinthorsdottir V, et al. Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nat Genet. 2010;42(7):579–89. doi:10.1038/ng.609.
-
(2010)
Nat Genet
, vol.42
, Issue.7
, pp. 579-589
-
-
Voight, B.F.1
Scott, L.J.2
Steinthorsdottir, V.3
-
38
-
-
42349106044
-
Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes
-
COI: 1:CAS:528:DC%2BD1cXltFylurY%3D, PID: 18372903
-
Zeggini E, Scott LJ, Saxena R, et al. Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. Nat Genet. 2008;40(5):638–45. doi:10.1038/ng.120.
-
(2008)
Nat Genet
, vol.40
, Issue.5
, pp. 638-645
-
-
Zeggini, E.1
Scott, L.J.2
Saxena, R.3
-
39
-
-
84655162045
-
Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in East Asians
-
COI: 1:CAS:528:DC%2BC3MXhs1eitr7P
-
Cho YS, Chen CH, Hu C, et al. Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in East Asians. Nat Genet. 2012;44(1):67–72. doi:10.1038/ng.1019.
-
(2012)
Nat Genet
, vol.44
, Issue.1
, pp. 67-72
-
-
Cho, Y.S.1
Chen, C.H.2
Hu, C.3
-
40
-
-
84872033833
-
A genome-wide association study identifies GRK5 and RASGRP1 as type 2 diabetes loci in Chinese Hans
-
COI: 1:CAS:528:DC%2BC3sXlt1KjsQ%3D%3D, PID: 22961080
-
Li H, Gan W, Lu L, et al. A genome-wide association study identifies GRK5 and RASGRP1 as type 2 diabetes loci in Chinese Hans. Diabetes. 2013;62(1):291–8. doi:10.2337/db12-0454.
-
(2013)
Diabetes
, vol.62
, Issue.1
, pp. 291-298
-
-
Li, H.1
Gan, W.2
Lu, L.3
-
41
-
-
77954172286
-
Genetic variants at 2q24 are associated with susceptibility to type 2 diabetes
-
COI: 1:CAS:528:DC%2BC3cXntlCquro%3D, PID: 20418489
-
Qi L, Cornelis MC, Kraft P, et al. Genetic variants at 2q24 are associated with susceptibility to type 2 diabetes. Hum Mol Genet. 2010;19(13):2706–15. doi:10.1093/hmg/ddq156.
-
(2010)
Hum Mol Genet
, vol.19
, Issue.13
, pp. 2706-2715
-
-
Qi, L.1
Cornelis, M.C.2
Kraft, P.3
-
42
-
-
78049438674
-
Identification of new genetic risk variants for type 2 diabetes
-
PID: 20862305
-
Shu XO, Long J, Cai Q, et al. Identification of new genetic risk variants for type 2 diabetes. PLoS Genet. 2010;6(9):e1001127. doi:10.1371/journal.pgen.1001127.
-
(2010)
PLoS Genet
, vol.6
, Issue.9
, pp. e1001127
-
-
Shu, X.O.1
Long, J.2
Cai, Q.3
-
43
-
-
77649214654
-
A genome-wide association study identifies susceptibility variants for type 2 diabetes in Han Chinese
-
PID: 20174558
-
Tsai FJ, Yang CF, Chen CC, et al. A genome-wide association study identifies susceptibility variants for type 2 diabetes in Han Chinese. PLoS Genet. 2010;6(2):e1000847. doi:10.1371/journal.pgen.1000847.
-
(2010)
PLoS Genet
, vol.6
, Issue.2
, pp. e1000847
-
-
Tsai, F.J.1
Yang, C.F.2
Chen, C.C.3
-
44
-
-
77957553197
-
A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B
-
COI: 1:CAS:528:DC%2BC3cXhtFWksrfE, PID: 20818381
-
Yamauchi T, Hara K, Maeda S, et al. A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B. Nat Genet. 2010;42(10):864–8. doi:10.1038/ng.660.
-
(2010)
Nat Genet
, vol.42
, Issue.10
, pp. 864-868
-
-
Yamauchi, T.1
Hara, K.2
Maeda, S.3
-
45
-
-
67650248695
-
Confirmation of multiple risk loci and genetic impacts by a genome-wide association study of type 2 diabetes in the Japanese population
-
COI: 1:CAS:528:DC%2BD1MXos1Gjsr4%3D, PID: 19401414
-
Takeuchi F, Serizawa M, Yamamoto K, et al. Confirmation of multiple risk loci and genetic impacts by a genome-wide association study of type 2 diabetes in the Japanese population. Diabetes. 2009;58(7):1690–9. doi:10.2337/db08-1494.
-
(2009)
Diabetes
, vol.58
, Issue.7
, pp. 1690-1699
-
-
Takeuchi, F.1
Serizawa, M.2
Yamamoto, K.3
-
46
-
-
80053385333
-
Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci
-
COI: 1:CAS:528:DC%2BC3MXhtV2gtrfK, PID: 21874001
-
Kooner JS, Saleheen D, Sim X, et al. Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci. Nat Genet. 2011;43(10):984–9. doi:10.1038/ng.921.
-
(2011)
Nat Genet
, vol.43
, Issue.10
, pp. 984-989
-
-
Kooner, J.S.1
Saleheen, D.2
Sim, X.3
-
47
-
-
84874418247
-
Genome-wide association study for type 2 diabetes in Indians identifies a new susceptibility locus at 2q21
-
COI: 1:CAS:528:DC%2BC3sXjsFGqsL0%3D, PID: 23209189
-
Tabassum R, Chauhan G, Dwivedi OP, et al. Genome-wide association study for type 2 diabetes in Indians identifies a new susceptibility locus at 2q21. Diabetes. 2013;62(3):977–86. doi:10.2337/db12-0406.
-
(2013)
Diabetes
, vol.62
, Issue.3
, pp. 977-986
-
-
Tabassum, R.1
Chauhan, G.2
Dwivedi, O.P.3
-
48
-
-
79960905856
-
Genome-wide association study of type 2 diabetes in a sample from Mexico City and a meta-analysis of a Mexican-American sample from Starr County Texas
-
COI: 1:STN:280:DC%2BC3MnmtlWgsw%3D%3D
-
Parra EJ, Below JE, Krithika S, et al. Genome-wide association study of type 2 diabetes in a sample from Mexico City and a meta-analysis of a Mexican-American sample from Starr County Texas. Diabetol. 2011;54(8):2038–46. doi:10.1007/s00125-011-2172-y.
-
(2011)
Diabetol
, vol.54
, Issue.8
, pp. 2038-2046
-
-
Parra, E.J.1
Below, J.E.2
Krithika, S.3
-
49
-
-
84855405312
-
A genome-wide association search for type 2 diabetes genes in African Americans
-
COI: 1:CAS:528:DC%2BC38XptF2muw%3D%3D, PID: 22238593
-
Palmer ND, McDonough CW, Hicks PJ, et al. A genome-wide association search for type 2 diabetes genes in African Americans. PLoS One. 2012;7(1):e29202. doi:10.1371/journal.pone.0029202.
-
(2012)
PLoS One
, vol.7
, Issue.1
, pp. e29202
-
-
Palmer, N.D.1
McDonough, C.W.2
Hicks, P.J.3
-
50
-
-
84895868553
-
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility
-
This is a recent trans-ethnic GWAS of T2D including cases and controls of European, east Asian, south Asian, Mexican and Mexican American ancestry. Seven additional T2D susceptibility loci were identified in this study
-
Replication DIG, Meta-analysis C. Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nat Genet. 2014;46(3):234–44. doi:10.1038/ng.2897. This is a recent trans-ethnic GWAS of T2D including cases and controls of European, east Asian, south Asian, Mexican and Mexican American ancestry. Seven additional T2D susceptibility loci were identified in this study.
-
(2014)
Nat Genet
, vol.46
, Issue.3
, pp. 234-244
-
-
Replication, D.I.G.1
Meta-analysis, C.2
-
51
-
-
44749085712
-
Newly identified loci highlight beta cell dysfunction as a key cause of type 2 diabetes: where are the insulin resistance genes?
-
COI: 1:CAS:528:DC%2BD1cXmslWgs7w%3D, PID: 18504548
-
Florez JC. Newly identified loci highlight beta cell dysfunction as a key cause of type 2 diabetes: where are the insulin resistance genes? Diabetologia. 2008;51(7):1100–10. doi:10.1007/s00125-008-1025-9.
-
(2008)
Diabetologia
, vol.51
, Issue.7
, pp. 1100-1110
-
-
Florez, J.C.1
-
52
-
-
78049337953
-
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index
-
COI: 1:CAS:528:DC%2BC3cXht1KmsL%2FN, PID: 20935630
-
Speliotes EK, Willer CJ, Berndt SI, et al. Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet. 2010;42(11):937–48. doi:10.1038/ng.686.
-
(2010)
Nat Genet
, vol.42
, Issue.11
, pp. 937-948
-
-
Speliotes, E.K.1
Willer, C.J.2
Berndt, S.I.3
-
53
-
-
34547625955
-
Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits
-
PID: 17658951
-
Scuteri A, Sanna S, Chen WM, et al. Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits. PLoS Genet. 2007;3(7):e115. doi:10.1371/journal.pgen.0030115.
-
(2007)
PLoS Genet
, vol.3
, Issue.7
, pp. e115
-
-
Scuteri, A.1
Sanna, S.2
Chen, W.M.3
-
54
-
-
34248594090
-
A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity
-
COI: 1:CAS:528:DC%2BD2sXltVentL0%3D, PID: 17434869
-
Frayling TM, Timpson NJ, Weedon MN, et al. A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science. 2007;316(5826):889–94. doi:10.1126/science.1141634.
-
(2007)
Science
, vol.316
, Issue.5826
, pp. 889-894
-
-
Frayling, T.M.1
Timpson, N.J.2
Weedon, M.N.3
-
55
-
-
44349142294
-
Common variants near MC4R are associated with fat mass, weight and risk of obesity
-
COI: 1:CAS:528:DC%2BD1cXmsVejsLo%3D, PID: 18454148
-
Loos RJ, Lindgren CM, Li S, et al. Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nat Genet. 2008;40(6):768–75. doi:10.1038/ng.140.
-
(2008)
Nat Genet
, vol.40
, Issue.6
, pp. 768-775
-
-
Loos, R.J.1
Lindgren, C.M.2
Li, S.3
-
56
-
-
58149163142
-
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation
-
COI: 1:CAS:528:DC%2BD1cXhsV2hsrnK, PID: 19079261
-
Willer CJ, Speliotes EK, Loos RJ, et al. Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet. 2009;41(1):25–34. doi:10.1038/ng.287.
-
(2009)
Nat Genet
, vol.41
, Issue.1
, pp. 25-34
-
-
Willer, C.J.1
Speliotes, E.K.2
Loos, R.J.3
-
57
-
-
58149163141
-
Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity
-
COI: 1:CAS:528:DC%2BD1cXhsV2hsrjO, PID: 19079260
-
Thorleifsson G, Walters GB, Gudbjartsson DF, et al. Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity. Nat Genet. 2009;41(1):18–24. doi:10.1038/ng.274.
-
(2009)
Nat Genet
, vol.41
, Issue.1
, pp. 18-24
-
-
Thorleifsson, G.1
Walters, G.B.2
Gudbjartsson, D.F.3
-
58
-
-
84923171580
-
Genetic studies of body mass index yield new insights for obesity biology
-
COI: 1:CAS:528:DC%2BC2MXislehtL8%3D, PID: 25673413, This is the most recent GWAS in up to 339,224 individuals identifying 56 additional loci (97 loci in total) associated with BMI
-
Locke AE, Kahali B, Berndt SI. Genetic studies of body mass index yield new insights for obesity biology. Nature. 2015;518(7538):197–206. doi:10.1038/nature14177. This is the most recent GWAS in up to 339,224 individuals identifying 56 additional loci (97 loci in total) associated with BMI.
-
(2015)
Nature
, vol.518
, Issue.7538
, pp. 197-206
-
-
Locke, A.E.1
Kahali, B.2
Berndt, S.I.3
-
59
-
-
67651236725
-
Genome-wide association scan meta-analysis identifies three loci influencing adiposity and fat distribution
-
PID: 19557161
-
Lindgren CM, Heid IM, Randall JC, et al. Genome-wide association scan meta-analysis identifies three loci influencing adiposity and fat distribution. PLoS Genet. 2009;5(6):e1000508. doi:10.1371/journal.pgen.1000508.
-
(2009)
PLoS Genet
, vol.5
, Issue.6
, pp. e1000508
-
-
Lindgren, C.M.1
Heid, I.M.2
Randall, J.C.3
-
60
-
-
67651216024
-
NRXN3 is a novel locus for waist circumference: a genome-wide association study from the CHARGE Consortium
-
PID: 19557197
-
Heard-Costa NL, Zillikens MC, Monda KL, et al. NRXN3 is a novel locus for waist circumference: a genome-wide association study from the CHARGE Consortium. PLoS Genet. 2009;5(6):e1000539. doi:10.1371/journal.pgen.1000539.
-
(2009)
PLoS Genet
, vol.5
, Issue.6
, pp. e1000539
-
-
Heard-Costa, N.L.1
Zillikens, M.C.2
Monda, K.L.3
-
61
-
-
78049349396
-
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution
-
COI: 1:CAS:528:DC%2BC3cXht1Kms7vO, PID: 20935629
-
Heid IM, Jackson AU, Randall JC, et al. Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet. 2010;42(11):949–60. doi:10.1038/ng.685.
-
(2010)
Nat Genet
, vol.42
, Issue.11
, pp. 949-960
-
-
Heid, I.M.1
Jackson, A.U.2
Randall, J.C.3
-
62
-
-
84923169934
-
New genetic loci link adipose and insulin biology to body fat distribution
-
COI: 1:CAS:528:DC%2BC2MXisleht7w%3D, PID: 25673412, This is the most recent GWAS in up to 224,459 individuals identifying 33 additional loci (49 loci in total) associated with WHRadjBMI
-
Shungin D, Winkler TW, Croteau-Chonka DC. New genetic loci link adipose and insulin biology to body fat distribution. Nature. 2015;518(7538):187–96. doi:10.1038/nature14132. This is the most recent GWAS in up to 224,459 individuals identifying 33 additional loci (49 loci in total) associated with WHRadjBMI.
-
(2015)
Nature
, vol.518
, Issue.7538
, pp. 187-196
-
-
Shungin, D.1
Winkler, T.W.2
Croteau-Chonka, D.C.3
-
63
-
-
41749090524
-
Genome wide association (GWA) study for early onset extreme obesity supports the role of fat mass and obesity associated gene (FTO) variants
-
PID: 18159244
-
Hinney A, Nguyen TT, Scherag A, et al. Genome wide association (GWA) study for early onset extreme obesity supports the role of fat mass and obesity associated gene (FTO) variants. PLoS One. 2007;2(12):e1361. doi:10.1371/journal.pone.0001361.
-
(2007)
PLoS One
, vol.2
, Issue.12
, pp. e1361
-
-
Hinney, A.1
Nguyen, T.T.2
Scherag, A.3
-
64
-
-
59149097625
-
Genome-wide association study for early-onset and morbid adult obesity identifies three new risk loci in European populations
-
COI: 1:CAS:528:DC%2BD1MXntFGktg%3D%3D, PID: 19151714
-
Meyre D, Delplanque J, Chevre JC, et al. Genome-wide association study for early-onset and morbid adult obesity identifies three new risk loci in European populations. Nat Genet. 2009;41(2):157–9. doi:10.1038/ng.301.
-
(2009)
Nat Genet
, vol.41
, Issue.2
, pp. 157-159
-
-
Meyre, D.1
Delplanque, J.2
Chevre, J.C.3
-
65
-
-
77952405825
-
Two new Loci for body-weight regulation identified in a joint analysis of genome-wide association studies for early-onset extreme obesity in French and German study groups
-
PID: 20421936
-
Scherag A, Dina C, Hinney A, et al. Two new Loci for body-weight regulation identified in a joint analysis of genome-wide association studies for early-onset extreme obesity in French and German study groups. PLoS Genet. 2010;6(4):e1000916. doi:10.1371/journal.pgen.1000916.
-
(2010)
PLoS Genet
, vol.6
, Issue.4
, pp. e1000916
-
-
Scherag, A.1
Dina, C.2
Hinney, A.3
-
66
-
-
80052840370
-
Genome-wide population-based association study of extremely overweight young adults—the GOYA study
-
COI: 1:CAS:528:DC%2BC3MXht1OmsrbN, PID: 21935397
-
Paternoster L, Evans DM, Nohr EA, et al. Genome-wide population-based association study of extremely overweight young adults—the GOYA study. PLoS One. 2011;6(9):e24303. doi:10.1371/journal.pone.0024303.
-
(2011)
PLoS One
, vol.6
, Issue.9
, pp. e24303
-
-
Paternoster, L.1
Evans, D.M.2
Nohr, E.A.3
-
67
-
-
79955711085
-
A genome-wide association study on obesity and obesity-related traits
-
COI: 1:CAS:528:DC%2BC3MXls1Kku7o%3D, PID: 21552555
-
Wang K, Li WD, Zhang CK, et al. A genome-wide association study on obesity and obesity-related traits. PLoS One. 2011;6(4):e18939. doi:10.1371/journal.pone.0018939.
-
(2011)
PLoS One
, vol.6
, Issue.4
, pp. e18939
-
-
Wang, K.1
Li, W.D.2
Zhang, C.K.3
-
68
-
-
84878569025
-
Genome-wide SNP and CNV analysis identifies common and low-frequency variants associated with severe early-onset obesity
-
COI: 1:CAS:528:DC%2BC3sXltlOnsb8%3D, PID: 23563609
-
Wheeler E, Huang N, Bochukova EG, et al. Genome-wide SNP and CNV analysis identifies common and low-frequency variants associated with severe early-onset obesity. Nat Genet. 2013;45(5):513–7. doi:10.1038/ng.2607.
-
(2013)
Nat Genet
, vol.45
, Issue.5
, pp. 513-517
-
-
Wheeler, E.1
Huang, N.2
Bochukova, E.G.3
-
69
-
-
84878594902
-
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture
-
COI: 1:CAS:528:DC%2BC3sXltlOmtL4%3D, PID: 23563607
-
Berndt SI, Gustafsson S, Magi R, et al. Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Nat Genet. 2013;45(5):501–12. doi:10.1038/ng.2606.
-
(2013)
Nat Genet
, vol.45
, Issue.5
, pp. 501-512
-
-
Berndt, S.I.1
Gustafsson, S.2
Magi, R.3
-
70
-
-
84862777036
-
Meta-analysis identifies common variants associated with body mass index in East Asians
-
COI: 1:CAS:528:DC%2BC38XisVKkt7o%3D, PID: 22344219
-
Wen W, Cho YS, Zheng W, et al. Meta-analysis identifies common variants associated with body mass index in East Asians. Nat Genet. 2012;44(3):307–11. doi:10.1038/ng.1087.
-
(2012)
Nat Genet
, vol.44
, Issue.3
, pp. 307-311
-
-
Wen, W.1
Cho, Y.S.2
Zheng, W.3
-
71
-
-
84884607859
-
Genome-wide association of body fat distribution in African ancestry populations suggests new loci
-
COI: 1:CAS:528:DC%2BC3sXhsVagtLjJ, PID: 23966867
-
Liu CT, Monda KL, Taylor KC, et al. Genome-wide association of body fat distribution in African ancestry populations suggests new loci. PLoS Genet. 2013;9(8):e1003681. doi:10.1371/journal.pgen.1003681.
-
(2013)
PLoS Genet
, vol.9
, Issue.8
, pp. e1003681
-
-
Liu, C.T.1
Monda, K.L.2
Taylor, K.C.3
-
72
-
-
84878720938
-
A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry
-
COI: 1:CAS:528:DC%2BC3sXlsl2gtLs%3D, PID: 23583978
-
Monda KL, Chen GK, Taylor KC, et al. A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry. Nat Genet. 2013;45(6):690–6. doi:10.1038/ng.2608.
-
(2013)
Nat Genet
, vol.45
, Issue.6
, pp. 690-696
-
-
Monda, K.L.1
Chen, G.K.2
Taylor, K.C.3
-
73
-
-
84865640231
-
Variability in the heritability of body mass index: a systematic review and meta-regression
-
Elks CE, den Hoed M, Zhao JH, et al. Variability in the heritability of body mass index: a systematic review and meta-regression. Front Endocrinol (Lausanne). 2012;3:29. doi:10.3389/fendo.2012.00029.
-
(2012)
Front Endocrinol (Lausanne)
, vol.3
, pp. 29
-
-
Elks, C.E.1
den Hoed, M.2
Zhao, J.H.3
-
74
-
-
84860350999
-
A genome-wide association meta-analysis identifies new childhood obesity loci
-
COI: 1:CAS:528:DC%2BC38XltFOgsbw%3D, PID: 22484627
-
Bradfield JP, Taal HR, Timpson NJ, et al. A genome-wide association meta-analysis identifies new childhood obesity loci. Nat Genet. 2012;44(5):526–31. doi:10.1038/ng.2247.
-
(2012)
Nat Genet
, vol.44
, Issue.5
, pp. 526-531
-
-
Bradfield, J.P.1
Taal, H.R.2
Timpson, N.J.3
-
75
-
-
84881581499
-
Genome-wide analysis of BMI in adolescents and young adults reveals additional insight into the effects of genetic loci over the life course
-
COI: 1:CAS:528:DC%2BC3sXht1CktLvE, PID: 23669352
-
Graff M, Ngwa JS, Workalemahu T, et al. Genome-wide analysis of BMI in adolescents and young adults reveals additional insight into the effects of genetic loci over the life course. Hum Mol Genet. 2013;22(17):3597–607. doi:10.1093/hmg/ddt205.
-
(2013)
Hum Mol Genet
, vol.22
, Issue.17
, pp. 3597-3607
-
-
Graff, M.1
Ngwa, J.S.2
Workalemahu, T.3
-
76
-
-
84892389710
-
EMR-linked GWAS study: investigation of variation landscape of loci for body mass index in children
-
PID: 24348519
-
Namjou B, Keddache M, Marsolo K, et al. EMR-linked GWAS study: investigation of variation landscape of loci for body mass index in children. Front Genet. 2013;4:268. doi:10.3389/fgene.2013.00268.
-
(2013)
Front Genet
, vol.4
, pp. 268
-
-
Namjou, B.1
Keddache, M.2
Marsolo, K.3
-
77
-
-
67349188883
-
A large-scale genome-wide association study of Asian populations uncovers genetic factors influencing eight quantitative traits
-
COI: 1:CAS:528:DC%2BD1MXltValt7k%3D, PID: 19396169
-
Cho YS, Go MJ, Kim YJ, et al. A large-scale genome-wide association study of Asian populations uncovers genetic factors influencing eight quantitative traits. Nat Genet. 2009;41(5):527–34. doi:10.1038/ng.357.
-
(2009)
Nat Genet
, vol.41
, Issue.5
, pp. 527-534
-
-
Cho, Y.S.1
Go, M.J.2
Kim, Y.J.3
-
78
-
-
34249777814
-
Variation in FTO contributes to childhood obesity and severe adult obesity
-
COI: 1:CAS:528:DC%2BD2sXlvVSgtL0%3D, PID: 17496892
-
Dina C, Meyre D, Gallina S, et al. Variation in FTO contributes to childhood obesity and severe adult obesity. Nat Genet. 2007;39(6):724–6. doi:10.1038/ng2048.
-
(2007)
Nat Genet
, vol.39
, Issue.6
, pp. 724-726
-
-
Dina, C.1
Meyre, D.2
Gallina, S.3
-
79
-
-
84862564504
-
Association of genetic variation in FTO with risk of obesity and type 2 diabetes with data from 96,551 East and South Asians
-
COI: 1:CAS:528:DC%2BC38XjsF2qtLc%3D, PID: 22109280
-
Li H, Kilpelainen TO, Liu C, et al. Association of genetic variation in FTO with risk of obesity and type 2 diabetes with data from 96,551 East and South Asians. Diabetologia. 2012;55(4):981–95. doi:10.1007/s00125-011-2370-7.
-
(2012)
Diabetologia
, vol.55
, Issue.4
, pp. 981-995
-
-
Li, H.1
Kilpelainen, T.O.2
Liu, C.3
-
80
-
-
84862822438
-
Common variants at CDKAL1 and KLF9 are associated with body mass index in East Asian populations
-
COI: 1:CAS:528:DC%2BC38XisVKktrk%3D, PID: 22344221
-
Okada Y, Kubo M, Ohmiya H, et al. Common variants at CDKAL1 and KLF9 are associated with body mass index in East Asian populations. Nat Genet. 2012;44(3):302–6. doi:10.1038/ng.1086.
-
(2012)
Nat Genet
, vol.44
, Issue.3
, pp. 302-306
-
-
Okada, Y.1
Kubo, M.2
Ohmiya, H.3
-
81
-
-
84879326263
-
The role of adiposity in cardiometabolic traits: a Mendelian randomization analysis
-
PID: 23824655
-
Fall T, Hagg S, Magi R, et al. The role of adiposity in cardiometabolic traits: a Mendelian randomization analysis. PLoS Med. 2013;10(6):e1001474. doi:10.1371/journal.pmed.1001474.
-
(2013)
PLoS Med
, vol.10
, Issue.6
, pp. e1001474
-
-
Fall, T.1
Hagg, S.2
Magi, R.3
-
82
-
-
36749041363
-
The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase
-
COI: 1:CAS:528:DC%2BD2sXhtlGmtLbI, PID: 17991826
-
Gerken T, Girard CA, Tung YC, et al. The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase. Science. 2007;318(5855):1469–72. doi:10.1126/science.1151710.
-
(2007)
Science
, vol.318
, Issue.5855
, pp. 1469-1472
-
-
Gerken, T.1
Girard, C.A.2
Tung, Y.C.3
-
83
-
-
77649303960
-
Hypothalamic-specific manipulation of Fto, the ortholog of the human obesity gene FTO, affects food intake in rats
-
PID: 20098739
-
Tung YC, Ayuso E, Shan X, et al. Hypothalamic-specific manipulation of Fto, the ortholog of the human obesity gene FTO, affects food intake in rats. PLoS One. 2010;5(1):e8771. doi:10.1371/journal.pone.0008771.
-
(2010)
PLoS One
, vol.5
, Issue.1
, pp. e8771
-
-
Tung, Y.C.1
Ayuso, E.2
Shan, X.3
-
84
-
-
84897855294
-
Obesity-associated variants within FTO form long-range functional connections with IRX3
-
COI: 1:CAS:528:DC%2BC2cXks1Wlsbk%3D, PID: 24646999
-
Smemo S, Tena JJ, Kim KH, et al. Obesity-associated variants within FTO form long-range functional connections with IRX3. Nature. 2014;507(7492):371–5. doi:10.1038/nature13138.
-
(2014)
Nature
, vol.507
, Issue.7492
, pp. 371-375
-
-
Smemo, S.1
Tena, J.J.2
Kim, K.H.3
-
85
-
-
75749112078
-
Replication of association between a common variant near melanocortin-4 receptor gene and obesity-related traits in Asian Sikhs
-
COI: 1:CAS:528:DC%2BC3cXht1Kks7g%3D
-
Been LF, Nath SK, Ralhan SK, et al. Replication of association between a common variant near melanocortin-4 receptor gene and obesity-related traits in Asian Sikhs. Obesity (Silver Spring). 2010;18(2):425–9. doi:10.1038/oby.2009.254.
-
(2010)
Obesity (Silver Spring)
, vol.18
, Issue.2
, pp. 425-429
-
-
Been, L.F.1
Nath, S.K.2
Ralhan, S.K.3
-
86
-
-
77749233777
-
Obesity susceptibility genetic variants identified from recent genome-wide association studies: implications in a Chinese population
-
COI: 1:CAS:528:DC%2BC3cXjs1Kqtbo%3D, PID: 20061430
-
Cheung CY, Tso AW, Cheung BM, et al. Obesity susceptibility genetic variants identified from recent genome-wide association studies: implications in a Chinese population. J Clin Endocrinol Metab. 2010;95(3):1395–403. doi:10.1210/jc.2009-1465.
-
(2010)
J Clin Endocrinol Metab
, vol.95
, Issue.3
, pp. 1395-1403
-
-
Cheung, C.Y.1
Tso, A.W.2
Cheung, B.M.3
-
87
-
-
84858282155
-
Implication of European-derived adiposity loci in African Americans
-
COI: 1:CAS:528:DC%2BC38XktVansbs%3D
-
Hester JM, Wing MR, Li J, et al. Implication of European-derived adiposity loci in African Americans. Int J Obes (Lond). 2012;36(3):465–73. doi:10.1038/ijo.2011.131.
-
(2012)
Int J Obes (Lond)
, vol.36
, Issue.3
, pp. 465-473
-
-
Hester, J.M.1
Wing, M.R.2
Li, J.3
-
88
-
-
0031662163
-
A frameshift mutation in human MC4R is associated with a dominant form of obesity
-
COI: 1:CAS:528:DyaK1cXms1amsLo%3D, PID: 9771699
-
Vaisse C, Clement K, Guy-Grand B, et al. A frameshift mutation in human MC4R is associated with a dominant form of obesity. Nat Genet. 1998;20(2):113–4. doi:10.1038/2407.
-
(1998)
Nat Genet
, vol.20
, Issue.2
, pp. 113-114
-
-
Vaisse, C.1
Clement, K.2
Guy-Grand, B.3
-
89
-
-
34547831224
-
The V103I polymorphism of the MC4R gene and obesity: population based studies and meta-analysis of 29 563 individuals
-
COI: 1:CAS:528:DC%2BD2sXpsF2qtbw%3D
-
Young EH, Wareham NJ, Farooqi S, et al. The V103I polymorphism of the MC4R gene and obesity: population based studies and meta-analysis of 29 563 individuals. Int J Obes (Lond). 2007;31(9):1437–41. doi:10.1038/sj.ijo.0803609.
-
(2007)
Int J Obes (Lond)
, vol.31
, Issue.9
, pp. 1437-1441
-
-
Young, E.H.1
Wareham, N.J.2
Farooqi, S.3
-
90
-
-
0041624549
-
Transgenic mice expressing green fluorescent protein under the control of the melanocortin-4 receptor promoter
-
COI: 1:CAS:528:DC%2BD3sXmtlyhtr4%3D, PID: 12904474
-
Liu H, Kishi T, Roseberry AG, et al. Transgenic mice expressing green fluorescent protein under the control of the melanocortin-4 receptor promoter. J Neurosci. 2003;23(18):7143–54.
-
(2003)
J Neurosci
, vol.23
, Issue.18
, pp. 7143-7154
-
-
Liu, H.1
Kishi, T.2
Roseberry, A.G.3
-
91
-
-
84893640057
-
Neural melanocortin receptors in obesity and related metabolic disorders
-
COI: 1:CAS:528:DC%2BC3sXoslWlu7g%3D, PID: 23680515
-
Girardet C, Butler AA. Neural melanocortin receptors in obesity and related metabolic disorders. Biochim Biophys Acta. 2014;1842(3):482–94. doi:10.1016/j.bbadis.2013.05.004.
-
(2014)
Biochim Biophys Acta
, vol.1842
, Issue.3
, pp. 482-494
-
-
Girardet, C.1
Butler, A.A.2
-
92
-
-
67349277177
-
Melanocortin-4 receptor activation inhibits c-Jun N-terminal kinase activity and promotes insulin signaling
-
COI: 1:CAS:528:DC%2BD1MXmsVSgtrs%3D, PID: 19463742
-
Chai B, Li JY, Zhang W, et al. Melanocortin-4 receptor activation inhibits c-Jun N-terminal kinase activity and promotes insulin signaling. Peptides. 2009;30(6):1098–104. doi:10.1016/j.peptides.2009.03.006.
-
(2009)
Peptides
, vol.30
, Issue.6
, pp. 1098-1104
-
-
Chai, B.1
Li, J.Y.2
Zhang, W.3
-
93
-
-
77956709758
-
Melanocortin-4 receptor activation promotes insulin-stimulated mTOR signaling
-
COI: 1:CAS:528:DC%2BC3cXhtFGjtLjO, PID: 20603172
-
Chai B, Li JY, Zhang W, et al. Melanocortin-4 receptor activation promotes insulin-stimulated mTOR signaling. Peptides. 2010;31(10):1888–93. doi:10.1016/j.peptides.2010.06.028.
-
(2010)
Peptides
, vol.31
, Issue.10
, pp. 1888-1893
-
-
Chai, B.1
Li, J.Y.2
Zhang, W.3
-
94
-
-
84555186717
-
Greater impact of melanocortin-4 receptor deficiency on rates of growth and risk of type 2 diabetes during childhood compared with adulthood in Pima Indians
-
COI: 1:CAS:528:DC%2BC38XltFSns70%3D, PID: 22106157
-
Thearle MS, Muller YL, Hanson RL, et al. Greater impact of melanocortin-4 receptor deficiency on rates of growth and risk of type 2 diabetes during childhood compared with adulthood in Pima Indians. Diabetes. 2012;61(1):250–7. doi:10.2337/db11-0708.
-
(2012)
Diabetes
, vol.61
, Issue.1
, pp. 250-257
-
-
Thearle, M.S.1
Muller, Y.L.2
Hanson, R.L.3
-
95
-
-
32544451924
-
Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes
-
COI: 1:CAS:528:DC%2BD28XhslCjtrw%3D, PID: 16415884
-
Grant SF, Thorleifsson G, Reynisdottir I, et al. Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes. Nat Genet. 2006;38(3):320–3. doi:10.1038/ng1732.
-
(2006)
Nat Genet
, vol.38
, Issue.3
, pp. 320-323
-
-
Grant, S.F.1
Thorleifsson, G.2
Reynisdottir, I.3
-
96
-
-
34548790660
-
The importance of TCF7L2
-
COI: 1:CAS:528:DC%2BD2sXht1CltrrI, PID: 17888129
-
Weedon MN. The importance of TCF7L2. Diabet Med. 2007;24(10):1062–6. doi:10.1111/j.1464-5491.2007.02258.x.
-
(2007)
Diabet Med
, vol.24
, Issue.10
, pp. 1062-1066
-
-
Weedon, M.N.1
-
97
-
-
64649096898
-
Type 2 diabetes susceptibility gene TCF7L2 and its role in beta-cell function
-
COI: 1:CAS:528:DC%2BD1MXktleitbs%3D, PID: 19336690
-
Gloyn AL, Braun M, Rorsman P. Type 2 diabetes susceptibility gene TCF7L2 and its role in beta-cell function. Diabetes. 2009;58(4):800–2. doi:10.2337/db09-0099.
-
(2009)
Diabetes
, vol.58
, Issue.4
, pp. 800-802
-
-
Gloyn, A.L.1
Braun, M.2
Rorsman, P.3
-
98
-
-
70349557826
-
Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia
-
COI: 1:CAS:528:DC%2BD1MXhtV2gsb%2FL, PID: 19734900
-
Rung J, Cauchi S, Albrechtsen A, et al. Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia. Nat Genet. 2009;41(10):1110–5. doi:10.1038/ng.443.
-
(2009)
Nat Genet
, vol.41
, Issue.10
, pp. 1110-1115
-
-
Rung, J.1
Cauchi, S.2
Albrechtsen, A.3
-
99
-
-
84859575363
-
Genetic determinants of common obesity and their value in prediction
-
COI: 1:CAS:528:DC%2BC38XlvFKlsrs%3D, PID: 22498250
-
Loos RJ. Genetic determinants of common obesity and their value in prediction. Best Pract Res Clin Endocrinol Metab. 2012;26(2):211–26. doi:10.1016/j.beem.2011.11.003.
-
(2012)
Best Pract Res Clin Endocrinol Metab
, vol.26
, Issue.2
, pp. 211-226
-
-
Loos, R.J.1
-
100
-
-
84861614905
-
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance
-
COI: 1:CAS:528:DC%2BC38XmvFCjtbw%3D, PID: 22581228
-
Manning AK, Hivert MF, Scott RA, et al. A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance. Nat Genet. 2012;44(6):659–69. doi:10.1038/ng.2274.
-
(2012)
Nat Genet
, vol.44
, Issue.6
, pp. 659-669
-
-
Manning, A.K.1
Hivert, M.F.2
Scott, R.A.3
-
101
-
-
84865693929
-
Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways
-
COI: 1:CAS:528:DC%2BC38XhtFOgsbzJ, PID: 22885924
-
Scott RA, Lagou V, Welch RP, et al. Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. Nat Genet. 2012;44(9):991–1005. doi:10.1038/ng.2385.
-
(2012)
Nat Genet
, vol.44
, Issue.9
, pp. 991-1005
-
-
Scott, R.A.1
Lagou, V.2
Welch, R.P.3
-
102
-
-
0031918624
-
The IRS-signalling system: a network of docking proteins that mediate insulin action
-
COI: 1:CAS:528:DyaK1cXjtlOnsr4%3D, PID: 9609109
-
White MF. The IRS-signalling system: a network of docking proteins that mediate insulin action. Mol Cell Biochem. 1998;182(1-2):3–11.
-
(1998)
Mol Cell Biochem
, vol.182
, Issue.1-2
, pp. 3-11
-
-
White, M.F.1
-
103
-
-
0038811794
-
Associations of hip and thigh circumferences independent of waist circumference with the incidence of type 2 diabetes: the Hoorn Study
-
COI: 1:CAS:528:DC%2BD3sXntlamsbk%3D, PID: 12716671
-
Snijder MB, Dekker JM, Visser M, et al. Associations of hip and thigh circumferences independent of waist circumference with the incidence of type 2 diabetes: the Hoorn Study. Am J Clin Nutr. 2003;77(5):1192–7.
-
(2003)
Am J Clin Nutr
, vol.77
, Issue.5
, pp. 1192-1197
-
-
Snijder, M.B.1
Dekker, J.M.2
Visser, M.3
-
104
-
-
0842333101
-
Trunk fat and leg fat have independent and opposite associations with fasting and postload glucose levels: the Hoorn study
-
PID: 14747216
-
Snijder MB, Dekker JM, Visser M, et al. Trunk fat and leg fat have independent and opposite associations with fasting and postload glucose levels: the Hoorn study. Diabetes Care. 2004;27(2):372–7.
-
(2004)
Diabetes Care
, vol.27
, Issue.2
, pp. 372-377
-
-
Snijder, M.B.1
Dekker, J.M.2
Visser, M.3
-
105
-
-
0035433418
-
Treatment of type 2 diabetes by adenoviral-mediated overexpression of the glucokinase regulatory protein
-
COI: 1:CAS:528:DC%2BD3MXlslKnu7g%3D, PID: 11473043
-
Slosberg ED, Desai UJ, Fanelli B, et al. Treatment of type 2 diabetes by adenoviral-mediated overexpression of the glucokinase regulatory protein. Diabetes. 2001;50(8):1813–20.
-
(2001)
Diabetes
, vol.50
, Issue.8
, pp. 1813-1820
-
-
Slosberg, E.D.1
Desai, U.J.2
Fanelli, B.3
-
106
-
-
49349084320
-
Compartmentalization and in vivo insulin-induced translocation of the insulin-signaling inhibitor Grb14 in rat liver
-
COI: 1:CAS:528:DC%2BD1cXhtFCqtr3F, PID: 18657188
-
Desbuquois B, Bereziat V, Authier F, et al. Compartmentalization and in vivo insulin-induced translocation of the insulin-signaling inhibitor Grb14 in rat liver. FEBS J. 2008;275(17):4363–77. doi:10.1111/j.1742-4658.2008.06583.x.
-
(2008)
FEBS J
, vol.275
, Issue.17
, pp. 4363-4377
-
-
Desbuquois, B.1
Bereziat, V.2
Authier, F.3
-
107
-
-
77955505564
-
Biological, clinical and population relevance of 95 loci for blood lipids
-
COI: 1:CAS:528:DC%2BC3cXhtVSmurfI, PID: 20686565
-
Teslovich TM, Musunuru K, Smith AV, et al. Biological, clinical and population relevance of 95 loci for blood lipids. Nature. 2010;466(7307):707–13. doi:10.1038/nature09270.
-
(2010)
Nature
, vol.466
, Issue.7307
, pp. 707-713
-
-
Teslovich, T.M.1
Musunuru, K.2
Smith, A.V.3
-
108
-
-
84879677633
-
Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits
-
COI: 1:CAS:528:DC%2BC3sXhtFGjsLrP, PID: 23754948
-
Randall JC, Winkler TW, Kutalik Z, et al. Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits. PLoS Genet. 2013;9(6):e1003500. doi:10.1371/journal.pgen.1003500.
-
(2013)
PLoS Genet
, vol.9
, Issue.6
, pp. e1003500
-
-
Randall, J.C.1
Winkler, T.W.2
Kutalik, Z.3
-
109
-
-
84876219189
-
Type 2 diabetes risk alleles near BCAR1 and in ANK1 associate with decreased beta-cell function whereas risk alleles near ANKRD55 and GRB14 associate with decreased insulin sensitivity in the Danish Inter99 cohort
-
COI: 1:CAS:528:DC%2BC3sXmtFegsrY%3D, PID: 23457408
-
Harder MN, Ribel-Madsen R, Justesen JM, et al. Type 2 diabetes risk alleles near BCAR1 and in ANK1 associate with decreased beta-cell function whereas risk alleles near ANKRD55 and GRB14 associate with decreased insulin sensitivity in the Danish Inter99 cohort. J Clin Endocrinol Metab. 2013;98(4):E801–6. doi:10.1210/jc.2012-4169.
-
(2013)
J Clin Endocrinol Metab
, vol.98
, Issue.4
, pp. E801-E806
-
-
Harder, M.N.1
Ribel-Madsen, R.2
Justesen, J.M.3
-
110
-
-
6944241725
-
Increased adipose tissue expression of Grb14 in several models of insulin resistance
-
PID: 15059968
-
Cariou B, Capitaine N, Le Marcis V, et al. Increased adipose tissue expression of Grb14 in several models of insulin resistance. FASEB J. 2004;18(9):965–7. doi:10.1096/fj.03-0824fje.
-
(2004)
FASEB J
, vol.18
, Issue.9
, pp. 965-967
-
-
Cariou, B.1
Capitaine, N.2
Le Marcis, V.3
-
111
-
-
10744225161
-
Improved glucose homeostasis and enhanced insulin signalling in Grb14-deficient mice
-
COI: 1:CAS:528:DC%2BD2cXhtV2qsb0%3D, PID: 14749734
-
Cooney GJ, Lyons RJ, Crew AJ, et al. Improved glucose homeostasis and enhanced insulin signalling in Grb14-deficient mice. EMBO J. 2004;23(3):582–93. doi:10.1038/sj.emboj.7600082.
-
(2004)
EMBO J
, vol.23
, Issue.3
, pp. 582-593
-
-
Cooney, G.J.1
Lyons, R.J.2
Crew, A.J.3
-
112
-
-
67649612829
-
Molecular determinants of Grb14-mediated inhibition of insulin signaling
-
COI: 1:CAS:528:DC%2BD1MXotlGju7w%3D, PID: 19359342
-
Goenaga D, Hampe C, Carre N, et al. Molecular determinants of Grb14-mediated inhibition of insulin signaling. Mol Endocrinol. 2009;23(7):1043–51. doi:10.1210/me.2008-0360.
-
(2009)
Mol Endocrinol
, vol.23
, Issue.7
, pp. 1043-1051
-
-
Goenaga, D.1
Hampe, C.2
Carre, N.3
-
113
-
-
0034253787
-
ADAMTS9, a novel member of the ADAM-TS/ metallospondin gene family
-
COI: 1:CAS:528:DC%2BD3cXlsVKltbk%3D, PID: 10936055
-
Clark ME, Kelner GS, Turbeville LA, et al. ADAMTS9, a novel member of the ADAM-TS/ metallospondin gene family. Genomics. 2000;67(3):343–50. doi:10.1006/geno.2000.6246.
-
(2000)
Genomics
, vol.67
, Issue.3
, pp. 343-350
-
-
Clark, M.E.1
Kelner, G.S.2
Turbeville, L.A.3
-
114
-
-
70349833653
-
Variant near ADAMTS9 known to associate with type 2 diabetes is related to insulin resistance in offspring of type 2 diabetes patients—EUGENE2 study
-
PID: 19789630
-
Boesgaard TW, Gjesing AP, Grarup N, et al. Variant near ADAMTS9 known to associate with type 2 diabetes is related to insulin resistance in offspring of type 2 diabetes patients—EUGENE2 study. PLoS One. 2009;4(9):e7236. doi:10.1371/journal.pone.0007236.
-
(2009)
PLoS One
, vol.4
, Issue.9
, pp. e7236
-
-
Boesgaard, T.W.1
Gjesing, A.P.2
Grarup, N.3
-
115
-
-
84879203883
-
PPARG2 Pro12Ala and ADAMTS9 rs4607103 as “insulin resistance loci” and “insulin secretion loci” in Italian individuals. The GENFIEV study and the Verona Newly Diagnosed Type 2 Diabetes Study (VNDS) 4
-
COI: 1:STN:280:DC%2BC3s7ktlWltg%3D%3D, PID: 23161442
-
Trombetta M, Bonetti S, Boselli ML, et al. PPARG2 Pro12Ala and ADAMTS9 rs4607103 as “insulin resistance loci” and “insulin secretion loci” in Italian individuals. The GENFIEV study and the Verona Newly Diagnosed Type 2 Diabetes Study (VNDS) 4. Acta Diabetol. 2013;50(3):401–8. doi:10.1007/s00592-012-0443-9.
-
(2013)
Acta Diabetol
, vol.50
, Issue.3
, pp. 401-408
-
-
Trombetta, M.1
Bonetti, S.2
Boselli, M.L.3
-
116
-
-
2342466734
-
Global prevalence of diabetes: estimates for the year 2000 and projections for 2030
-
PID: 15111519
-
Wild S, Roglic G, Green A, et al. Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes Care. 2004;27(5):1047–53.
-
(2004)
Diabetes Care
, vol.27
, Issue.5
, pp. 1047-1053
-
-
Wild, S.1
Roglic, G.2
Green, A.3
-
117
-
-
49249138836
-
Associations of adiponectin, resistin, and tumor necrosis factor-alpha with insulin resistance
-
COI: 1:CAS:528:DC%2BD1cXpvVOls7k%3D, PID: 18492747
-
Hivert MF, Sullivan LM, Fox CS, et al. Associations of adiponectin, resistin, and tumor necrosis factor-alpha with insulin resistance. J Clin Endocrinol Metab. 2008;93(8):3165–72. doi:10.1210/jc.2008-0425.
-
(2008)
J Clin Endocrinol Metab
, vol.93
, Issue.8
, pp. 3165-3172
-
-
Hivert, M.F.1
Sullivan, L.M.2
Fox, C.S.3
-
118
-
-
43449090395
-
Circulating adiponectin levels associate with inflammatory markers, insulin resistance and metabolic syndrome independent of obesity
-
COI: 1:CAS:528:DC%2BD1cXls1yrsro%3D
-
Hung J, McQuillan BM, Thompson PL, et al. Circulating adiponectin levels associate with inflammatory markers, insulin resistance and metabolic syndrome independent of obesity. Int J Obes (Lond). 2008;32(5):772–9. doi:10.1038/sj.ijo.0803793.
-
(2008)
Int J Obes (Lond)
, vol.32
, Issue.5
, pp. 772-779
-
-
Hung, J.1
McQuillan, B.M.2
Thompson, P.L.3
-
119
-
-
34250854033
-
Associations of adiponectin with metabolic and vascular risk parameters in the British Regional Heart Study reveal stronger links to insulin resistance-related than to coronory heart disease risk-related parameters
-
COI: 1:CAS:528:DC%2BD2sXmvVOntbg%3D
-
Wannamethee SG, Tchernova J, Whincup P, et al. Associations of adiponectin with metabolic and vascular risk parameters in the British Regional Heart Study reveal stronger links to insulin resistance-related than to coronory heart disease risk-related parameters. Int J Obes (Lond). 2007;31(7):1089–98. doi:10.1038/sj.ijo.0803544.
-
(2007)
Int J Obes (Lond)
, vol.31
, Issue.7
, pp. 1089-1098
-
-
Wannamethee, S.G.1
Tchernova, J.2
Whincup, P.3
-
120
-
-
0037031088
-
Adiponectin and development of type 2 diabetes in the Pima Indian population
-
COI: 1:CAS:528:DC%2BD38XltV2qs7Y%3D, PID: 12114044
-
Lindsay RS, Funahashi T, Hanson RL, et al. Adiponectin and development of type 2 diabetes in the Pima Indian population. Lancet. 2002;360(9326):57–8. doi:10.1016/S0140-6736(02)09335-2.
-
(2002)
Lancet
, vol.360
, Issue.9326
, pp. 57-58
-
-
Lindsay, R.S.1
Funahashi, T.2
Hanson, R.L.3
-
121
-
-
1842864234
-
Plasma adiponectin levels and risk of myocardial infarction in men
-
COI: 1:CAS:528:DC%2BD2cXjt1Wrt7Y%3D, PID: 15082700
-
Pischon T, Girman CJ, Hotamisligil GS, et al. Plasma adiponectin levels and risk of myocardial infarction in men. JAMA. 2004;291(14):1730–7. doi:10.1001/jama.291.14.1730.
-
(2004)
JAMA
, vol.291
, Issue.14
, pp. 1730-1737
-
-
Pischon, T.1
Girman, C.J.2
Hotamisligil, G.S.3
-
122
-
-
0037452139
-
Adiponectin and protection against type 2 diabetes mellitus
-
COI: 1:CAS:528:DC%2BD3sXkvVOlsQ%3D%3D, PID: 12547549
-
Spranger J, Kroke A, Mohlig M, et al. Adiponectin and protection against type 2 diabetes mellitus. Lancet. 2003;361(9353):226–8. doi:10.1016/S0140-6736(03)12255-6.
-
(2003)
Lancet
, vol.361
, Issue.9353
, pp. 226-228
-
-
Spranger, J.1
Kroke, A.2
Mohlig, M.3
-
123
-
-
0034999667
-
Hypoadiponectinemia in obesity and type 2 diabetes: close association with insulin resistance and hyperinsulinemia
-
COI: 1:CAS:528:DC%2BD3MXjs1OmsL0%3D, PID: 11344187
-
Weyer C, Funahashi T, Tanaka S, et al. Hypoadiponectinemia in obesity and type 2 diabetes: close association with insulin resistance and hyperinsulinemia. J Clin Endocrinol Metab. 2001;86(5):1930–5. doi:10.1210/jcem.86.5.7463.
-
(2001)
J Clin Endocrinol Metab
, vol.86
, Issue.5
, pp. 1930-1935
-
-
Weyer, C.1
Funahashi, T.2
Tanaka, S.3
-
124
-
-
33745192633
-
Leptin and adiponectin in relation to body fat percentage, waist to hip ratio and the apoB/apoA1 ratio in Asian Indian and Caucasian men and women
-
Smith J, Al-Amri M, Sniderman A, et al. Leptin and adiponectin in relation to body fat percentage, waist to hip ratio and the apoB/apoA1 ratio in Asian Indian and Caucasian men and women. Nutr Metab (Lond). 2006;3:18. doi:10.1186/1743-7075-3-18.
-
(2006)
Nutr Metab (Lond)
, vol.3
, pp. 18
-
-
Smith, J.1
Al-Amri, M.2
Sniderman, A.3
-
125
-
-
17944362243
-
The genetic basis of plasma variation in adiponectin, a global endophenotype for obesity and the metabolic syndrome
-
COI: 1:CAS:528:DC%2BD3MXmvFCku7w%3D, PID: 11549668
-
Comuzzie AG, Funahashi T, Sonnenberg G, et al. The genetic basis of plasma variation in adiponectin, a global endophenotype for obesity and the metabolic syndrome. J Clin Endocrinol Metab. 2001;86(9):4321–5. doi:10.1210/jcem.86.9.7878.
-
(2001)
J Clin Endocrinol Metab
, vol.86
, Issue.9
, pp. 4321-4325
-
-
Comuzzie, A.G.1
Funahashi, T.2
Sonnenberg, G.3
-
126
-
-
34248187069
-
Genetic influences of adiponectin on insulin resistance, type 2 diabetes, and cardiovascular disease
-
COI: 1:CAS:528:DC%2BD2sXltlantLc%3D, PID: 17303804
-
Menzaghi C, Trischitta V, Doria A. Genetic influences of adiponectin on insulin resistance, type 2 diabetes, and cardiovascular disease. Diabetes. 2007;56(5):1198–209. doi:10.2337/db06-0506.
-
(2007)
Diabetes
, vol.56
, Issue.5
, pp. 1198-1209
-
-
Menzaghi, C.1
Trischitta, V.2
Doria, A.3
-
127
-
-
18644369745
-
Single-nucleotide polymorphism haplotypes in the both proximal promoter and exon 3 of the APM1 gene modulate adipocyte-secreted adiponectin hormone levels and contribute to the genetic risk for type 2 diabetes in French Caucasians
-
COI: 1:CAS:528:DC%2BD38XnvVemtrk%3D, PID: 12354786
-
Vasseur F, Helbecque N, Dina C, et al. Single-nucleotide polymorphism haplotypes in the both proximal promoter and exon 3 of the APM1 gene modulate adipocyte-secreted adiponectin hormone levels and contribute to the genetic risk for type 2 diabetes in French Caucasians. Hum Mol Genet. 2002;11(21):2607–14.
-
(2002)
Hum Mol Genet
, vol.11
, Issue.21
, pp. 2607-2614
-
-
Vasseur, F.1
Helbecque, N.2
Dina, C.3
-
128
-
-
38149068433
-
The small G proteins of the Arf family and their regulators
-
COI: 1:CAS:528:DC%2BD2sXhtlCisrrK, PID: 17506703
-
Gillingham AK, Munro S. The small G proteins of the Arf family and their regulators. Annu Rev Cell Dev Biol. 2007;23:579–611. doi:10.1146/annurev.cellbio.23.090506.123209.
-
(2007)
Annu Rev Cell Dev Biol
, vol.23
, pp. 579-611
-
-
Gillingham, A.K.1
Munro, S.2
-
129
-
-
34147139995
-
The Arl4 family of small G proteins can recruit the cytohesin Arf6 exchange factors to the plasma membrane
-
COI: 1:CAS:528:DC%2BD2sXkt1ahtrw%3D, PID: 17398095
-
Hofmann I, Thompson A, Sanderson CM, et al. The Arl4 family of small G proteins can recruit the cytohesin Arf6 exchange factors to the plasma membrane. Curr Biol. 2007;17(8):711–6. doi:10.1016/j.cub.2007.03.007.
-
(2007)
Curr Biol
, vol.17
, Issue.8
, pp. 711-716
-
-
Hofmann, I.1
Thompson, A.2
Sanderson, C.M.3
-
130
-
-
78649468820
-
The genetics of type 2 diabetes: what have we learned from GWAS?
-
COI: 1:CAS:528:DC%2BC3MXmvVCitw%3D%3D, PID: 21091714
-
Billings LK, Florez JC. The genetics of type 2 diabetes: what have we learned from GWAS? Ann N Y Acad Sci. 2010;1212:59–77. doi:10.1111/j.1749-6632.2010.05838.x.
-
(2010)
Ann N Y Acad Sci
, vol.1212
, pp. 59-77
-
-
Billings, L.K.1
Florez, J.C.2
-
131
-
-
78649842241
-
Genomics, type 2 diabetes, and obesity
-
COI: 1:CAS:528:DC%2BC3cXhsFGkt7zO, PID: 21142536
-
McCarthy MI. Genomics, type 2 diabetes, and obesity. N Engl J Med. 2010;363(24):2339–50. doi:10.1056/NEJMra0906948.
-
(2010)
N Engl J Med
, vol.363
, Issue.24
, pp. 2339-2350
-
-
McCarthy, M.I.1
-
132
-
-
84898416576
-
Gender differences in non-glycemic responses to improved insulin sensitivity by pioglitazone treatment in patients with type 2 diabetes
-
COI: 1:CAS:528:DC%2BC2cXls1Wiu70%3D, PID: 23389468
-
Arnetz L, Dorkhan M, Alvarsson M, et al. Gender differences in non-glycemic responses to improved insulin sensitivity by pioglitazone treatment in patients with type 2 diabetes. Acta Diabetol. 2014;51(2):185–92. doi:10.1007/s00592-013-0457-y.
-
(2014)
Acta Diabetol
, vol.51
, Issue.2
, pp. 185-192
-
-
Arnetz, L.1
Dorkhan, M.2
Alvarsson, M.3
-
133
-
-
34548588284
-
Sexual dimorphism of body composition
-
PID: 17875489
-
Wells JC. Sexual dimorphism of body composition. Best Pract Res Clin Endocrinol Metab. 2007;21(3):415–30. doi:10.1016/j.beem.2007.04.007.
-
(2007)
Best Pract Res Clin Endocrinol Metab
, vol.21
, Issue.3
, pp. 415-430
-
-
Wells, J.C.1
-
134
-
-
2942650969
-
Adipose tissue as an endocrine organ
-
COI: 1:CAS:528:DC%2BD2cXmtlGqt7s%3D, PID: 15181022
-
Kershaw EE, Flier JS. Adipose tissue as an endocrine organ. J Clin Endocrinol Metab. 2004;89(6):2548–56. doi:10.1210/jc.2004-0395.
-
(2004)
J Clin Endocrinol Metab
, vol.89
, Issue.6
, pp. 2548-2556
-
-
Kershaw, E.E.1
Flier, J.S.2
|