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Volumn 36, Issue 3, 2012, Pages 465-473

Implication of European-derived adiposity loci in African Americans

Author keywords

African Americans; body mass index; genome wide association

Indexed keywords

ADULT; AFRICAN AMERICAN; ALLELE; ARTICLE; EUROPEAN AMERICAN; FEMALE; GENE; GENETIC ASSOCIATION; GENOME ANALYSIS; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; MC4R GENE; NEGR1 GENE; OBESITY; PRIORITY JOURNAL; SH2B1 GENE; SINGLE NUCLEOTIDE POLYMORPHISM; TMEM18 GENE;

EID: 84858282155     PISSN: 03070565     EISSN: 14765497     Source Type: Journal    
DOI: 10.1038/ijo.2011.131     Document Type: Article
Times cited : (49)

References (50)
  • 1
    • 64649083354 scopus 로고    scopus 로고
    • The incidence of co-morbidities related to obesity and overweight: A systematic review and meta-analysis
    • Guh DP, Zhang W, Bansback N, Amarsi Z, Birmingham CL, Anis AH. The incidence of co-morbidities related to obesity and overweight: a systematic review and meta-analysis. BMC Public Health 2009; 9: 88.
    • (2009) BMC Public Health , vol.9 , pp. 88
    • Guh, D.P.1    Zhang, W.2    Bansback, N.3    Amarsi, Z.4    Birmingham, C.L.5    Anis, A.H.6
  • 2
    • 0037048669 scopus 로고    scopus 로고
    • Prevalence and trends in obesity among US adults 1999-2000
    • Flegal KM, Carroll MD, Ogden CL, Johnson CL. Prevalence and trends in obesity among US adults, 1999-2000. JAMA 2002; 288: 1723-1727.
    • (2002) JAMA , vol.288 , pp. 1723-1727
    • Flegal, K.M.1    Carroll, M.D.2    Ogden, C.L.3    Johnson, C.L.4
  • 3
    • 74549140993 scopus 로고    scopus 로고
    • Prevalence and trends in obesity among US adults 1999-2008
    • Flegal KM, Carroll MD, Ogden CL, Curtin LR. Prevalence and trends in obesity among US adults, 1999-2008. JAMA 2010; 303: 235-241.
    • (2010) JAMA , vol.303 , pp. 235-241
    • Flegal, K.M.1    Carroll, M.D.2    Ogden, C.L.3    Curtin, L.R.4
  • 5
    • 0242383401 scopus 로고    scopus 로고
    • ObesityFis it a genetic disorder?
    • Loos RJ, Bouchard C. ObesityFis it a genetic disorder? J Intern Med 2003; 254: 401-425.
    • (2003) J Intern Med , vol.254 , pp. 401-425
    • Loos, R.J.1    Bouchard, C.2
  • 6
    • 0036690542 scopus 로고    scopus 로고
    • Genetic and environmental influences on body-fat measures among African-American twins
    • Nelson TL, Brandon DT, Wiggins SA, Whitfield KE. Genetic and environmental influences on body-fat measures among African-American twins. Obes Res 2002; 10: 733-739. (Pubitemid 135687513)
    • (2002) Obesity Research , vol.10 , Issue.8 , pp. 733-739
    • Nelson, T.L.1    Brandon, D.T.2    Wiggins, S.A.3    Whitfield, K.E.4
  • 10
    • 41749090524 scopus 로고    scopus 로고
    • Genome wide association (GWA) study for early onset extreme obesity supports the role of fat mass and obesity associated gene (FTO) variants
    • Hinney A, Nguyen TT, Scherag A, Friedel S, Bronner G, Muller TD et al. Genome wide association (GWA) study for early onset extreme obesity supports the role of fat mass and obesity associated gene (FTO) variants. PLoS One 2007; 2: e1361.
    • (2007) PLoS One , vol.2
    • Hinney, A.1    Nguyen, T.T.2    Scherag, A.3    Friedel, S.4    Bronner, G.5    Muller, T.D.6
  • 12
    • 34547625955 scopus 로고    scopus 로고
    • Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits
    • Scuteri A, Sanna S, Chen WM, Uda M, Albai G, Strait J et al. Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits. PLoS Genet 2007; 3: e115.
    • (2007) PLoS Genet , vol.3
    • Scuteri, A.1    Sanna, S.2    Chen, W.M.3    Uda, M.4    Albai, G.5    Strait, J.6
  • 16
    • 58149163142 scopus 로고    scopus 로고
    • Six new loci associated with body mass index highlight a neuronal influence on body weight regulation
    • Willer CJ, Speliotes EK, Loos RJ, Li S, Lindgren CM, Heid IM et al. Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet 2009; 41: 25-34.
    • (2009) Nat Genet , vol.41 , pp. 25-34
    • Willer, C.J.1    Speliotes, E.K.2    Loos, R.J.3    Li, S.4    Lindgren, C.M.5    Heid, I.M.6
  • 18
    • 59149097625 scopus 로고    scopus 로고
    • Genome-wide association study for early-onset and morbid adult obesity identifies three new risk loci in European populations
    • Meyre D, Delplanque J, Chevre JC, Lecoeur C, Lobbens S, Gallina S et al. Genome-wide association study for early-onset and morbid adult obesity identifies three new risk loci in European populations. Nat Genet 2009; 41: 157-159.
    • (2009) Nat Genet , vol.41 , pp. 157-159
    • Meyre, D.1    Delplanque, J.2    Chevre, J.C.3    Lecoeur, C.4    Lobbens, S.5    Gallina, S.6
  • 19
    • 67651236725 scopus 로고    scopus 로고
    • Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution
    • Lindgren CM, Heid IM, Randall JC, Lamina C, Steinthorsdottir V, Qi L et al. Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution. PLoS Genet 2009; 5: e1000508.
    • (2009) PLoS Genet , vol.5
    • Lindgren, C.M.1    Heid, I.M.2    Randall, J.C.3    Lamina, C.4    Steinthorsdottir, V.5    Qi, L.6
  • 20
    • 67651216024 scopus 로고    scopus 로고
    • NRXN3 is a novel locus for waist circumference: A genome-wide association study from the CHARGE Consortium
    • Heard-Costa NL, Zillikens MC, Monda KL, Johansson A, Harris TB, Fu M et al. NRXN3 is a novel locus for waist circumference: a genome-wide association study from the CHARGE Consortium. PLoS Genet 2009; 5: e1000539.
    • (2009) PLoS Genet , vol.5
    • Heard-Costa, N.L.1    Zillikens, M.C.2    Monda, K.L.3    Johansson, A.4    Harris, T.B.5    Fu, M.6
  • 22
    • 78049349396 scopus 로고    scopus 로고
    • Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution
    • Heid IM, Jackson AU, Randall JC, Winkler TW, Qi L, Steinthorsdottir V et al. Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet 2010; 42: 949-960.
    • (2010) Nat Genet , vol.42 , pp. 949-960
    • Heid, I.M.1    Jackson, A.U.2    Randall, J.C.3    Winkler, T.W.4    Qi, L.5    Steinthorsdottir, V.6
  • 23
    • 67349188883 scopus 로고    scopus 로고
    • A large-scale genome-wide association study of Asian populations uncovers genetic factors influencing eight quantitative traits
    • Cho YS, Go MJ, Kim YJ, Heo JY, Oh JH, Ban HJ et al. A large-scale genome-wide association study of Asian populations uncovers genetic factors influencing eight quantitative traits. Nat Genet 2009; 41: 527-534.
    • (2009) Nat Genet , vol.41 , pp. 527-534
    • Cho, Y.S.1    Go, M.J.2    Kim, Y.J.3    Heo, J.Y.4    Oh, J.H.5    Ban, H.J.6
  • 24
    • 55849104388 scopus 로고    scopus 로고
    • FTO variants are associated with obesity in the Chinese and Malay populations in Singapore
    • Tan JT, Dorajoo R, Seielstad M, Sim XL, Ong RT, Chia KS et al. FTO variants are associated with obesity in the Chinese and Malay populations in Singapore. Diabetes 2008; 57: 2851-2857.
    • (2008) Diabetes , vol.57 , pp. 2851-2857
    • Tan, J.T.1    Dorajoo, R.2    Seielstad, M.3    Sim, X.L.4    Ong, R.T.5    Chia, K.S.6
  • 25
    • 73649136827 scopus 로고    scopus 로고
    • Association between obesity and polymorphisms in SEC16B, TMEM18, GNPDA2, BDNF, FAIM2 and MC4R in a Japanese population
    • Hotta K, Nakamura M, Nakamura T, Matsuo T, Nakata Y, Kamohara S et al. Association between obesity and polymorphisms in SEC16B, TMEM18, GNPDA2, BDNF, FAIM2 and MC4R in a Japanese population. J Hum Genet 2009; 54: 727-731.
    • (2009) J Hum Genet , vol.54 , pp. 727-731
    • Hotta, K.1    Nakamura, M.2    Nakamura, T.3    Matsuo, T.4    Nakata, Y.5    Kamohara, S.6
  • 26
    • 77952746932 scopus 로고    scopus 로고
    • Implication of genetic variants near NEGR1 SEC16B, TMEM18, ETV5/DGKG, GNPDA2, LIN7C/BDNF, MTCH2, BCDIN3D/FAIM2, SH2B1, FTO, MC4R, and KCTD15 with obesity and type diabetes in 7705 Chinese
    • Ng MC, Tam CH, So WY, Ho JS, Chan AW, Lee HM et al. Implication of genetic variants near NEGR1, SEC16B, TMEM18, ETV5/DGKG, GNPDA2, LIN7C/BDNF, MTCH2, BCDIN3D/FAIM2, SH2B1, FTO, MC4R, and KCTD15 with obesity and type diabetes in 7705 Chinese. J Clin Endocrinol Metab 2010; 95: 2418-2425.
    • (2010) J Clin Endocrinol Metab , vol.95 , pp. 2418-2425
    • Ng, M.C.1    Tam, C.H.2    So, W.Y.3    Ho, J.S.4    Chan, A.W.5    Lee, H.M.6
  • 27
    • 67649744249 scopus 로고    scopus 로고
    • Investigation of the locus near MC4R with childhood obesity in Americans of European and African ancestry
    • Grant SF, Bradfield JP, Zhang H, Wang K, Kim CE, Annaiah K et al. Investigation of the locus near MC4R with childhood obesity in Americans of European and African ancestry. Obesity (Silver Spring) 2009; 17: 1461-1465.
    • (2009) Obesity (Silver Spring) , vol.17 , pp. 1461-1465
    • Grant, S.F.1    Bradfield, J.P.2    Zhang, H.3    Wang, K.4    Kim, C.E.5    Annaiah, K.6
  • 28
    • 77954168060 scopus 로고    scopus 로고
    • Genome-wide association of anthropometric traits in African-and African-derived populations
    • Kang SJ, Chiang CW, Palmer CD, Tayo BO, Lettre G, Butler JL et al. Genome-wide association of anthropometric traits in African-and African-derived populations. Hum Mol Genet 2010; 19: 2725-2738.
    • (2010) Hum Mol Genet , vol.19 , pp. 2725-2738
    • Kang, S.J.1    Chiang, C.W.2    Palmer, C.D.3    Tayo, B.O.4    Lettre, G.5    Butler, J.L.6
  • 29
    • 77957105975 scopus 로고    scopus 로고
    • Association of FTO gene variants with adiposity in African-American adolescents
    • Bollepalli S, Dolan LM, Deka R, Martin LJ. Association of FTO gene variants with adiposity in African-American adolescents. Obesity (Silver Spring) 2010; 18: 1959-1963.
    • (2010) Obesity (Silver Spring) , vol.18 , pp. 1959-1963
    • Bollepalli, S.1    Dolan, L.M.2    Deka, R.3    Martin, L.J.4
  • 30
    • 46249094941 scopus 로고    scopus 로고
    • Association analysis of the FTO gene with obesity in children of Caucasian and African ancestry reveals a common tagging SNP
    • Grant SF, Li M, Bradfield JP, Kim CE, Annaiah K, Santa E et al. Association analysis of the FTO gene with obesity in children of Caucasian and African ancestry reveals a common tagging SNP. PLoS One 2008; 3: e1746.
    • (2008) PLoS One , vol.3
    • Grant, S.F.1    Li, M.2    Bradfield, J.P.3    Kim, C.E.4    Annaiah, K.5    Santa, E.6
  • 31
    • 67349222934 scopus 로고    scopus 로고
    • Analysis of FTO gene variants with measures of obesity and glucose homeostasis in the IRAS Family Study
    • Wing MR, Ziegler J, Langefeld CD, Ng MC, Haffner SM, Norris JM et al. Analysis of FTO gene variants with measures of obesity and glucose homeostasis in the IRAS Family Study. Hum Genet 2009; 125: 615-626.
    • (2009) Hum Genet , vol.125 , pp. 615-626
    • Wing, M.R.1    Ziegler, J.2    Langefeld, C.D.3    Ng, M.C.4    Haffner, S.M.5    Norris, J.M.6
  • 32
    • 77954513650 scopus 로고    scopus 로고
    • Fine mapping of the association with obesity at the FTO locus in African-derived populations
    • Hassanein MT, Lyon HN, Nguyen TT, Akylbekova EL, Waters K, Lettre G et al. Fine mapping of the association with obesity at the FTO locus in African-derived populations. Hum Mol Genet 2010; 19: 2907-2916.
    • (2010) Hum Mol Genet , vol.19 , pp. 2907-2916
    • Hassanein, M.T.1    Lyon, H.N.2    Nguyen, T.T.3    Akylbekova, E.L.4    Waters, K.5    Lettre, G.6
  • 33
    • 73949101249 scopus 로고    scopus 로고
    • Non-muscle myosin heavy chain 9 gene MYH9 associations in African Americans with clinically diagnosed type diabetes mellitus-associated ESRD
    • Freedman BI, Hicks PJ, Bostrom MA, Comeau ME, Divers J, Bleyer AJ et al. Non-muscle myosin heavy chain 9 gene MYH9 associations in African Americans with clinically diagnosed type diabetes mellitus-associated ESRD. Nephrol Dial Transplant 2009; 24: 3366-3371.
    • (2009) Nephrol Dial Transplant , vol.24 , pp. 3366-3371
    • Freedman, B.I.1    Hicks, P.J.2    Bostrom, M.A.3    Comeau, M.E.4    Divers, J.5    Bleyer, A.J.6
  • 34
    • 77957136389 scopus 로고    scopus 로고
    • Regional adipose tissue associations with calcified atherosclerotic plaque: African American-diabetes heart study
    • Divers J, Wagenknecht LE, Bowden DW, Carr JJ, Hightower RC, Ding J et al. Regional adipose tissue associations with calcified atherosclerotic plaque: African American-diabetes heart study. Obesity (Silver Spring) 2010; 18: 2004-2009.
    • (2010) Obesity (Silver Spring) , vol.18 , pp. 2004-2009
    • Divers, J.1    Wagenknecht, L.E.2    Bowden, D.W.3    Carr, J.J.4    Hightower, R.C.5    Ding, J.6
  • 37
    • 0028811449 scopus 로고
    • The insulin resistance atherosclerosis study (IRAS) objectives, design, and recruitment results
    • Wagenknecht LE, Mayer EJ, Rewers M, Haffner S, Selby J, Borok GM et al. The insulin resistance atherosclerosis study (IRAS) objectives, design, and recruitment results. Ann Epidemiol 1995; 5: 464-472.
    • (1995) Ann Epidemiol , vol.5 , pp. 464-472
    • Wagenknecht, L.E.1    Mayer, E.J.2    Rewers, M.3    Haffner, S.4    Selby, J.5    Borok, G.M.6
  • 38
    • 0032231941 scopus 로고    scopus 로고
    • PedCheck: A program for identification of genotype incompatibilities in linkage analysis
    • DOI 10.1086/301904
    • O'Connell JR, Weeks DE. PedCheck: a program for identification of genotype incompatibilities in linkage analysis. Am J Hum Genet 1998; 63: 259-266. (Pubitemid 30428342)
    • (1998) American Journal of Human Genetics , vol.63 , Issue.1 , pp. 259-266
    • O'Connell, J.R.1    Weeks, D.E.2
  • 39
    • 50649103044 scopus 로고    scopus 로고
    • Exploration of the utility of ancestry informative markers for genetic association studies of African Americans with type 2 diabetes and end stage renal disease
    • Keene KL, Mychaleckyj JC, Leak TS, Smith SG, Perlegas PS, Divers J et al. Exploration of the utility of ancestry informative markers for genetic association studies of African Americans with type 2 diabetes and end stage renal disease. Hum Genet 2008; 124: 147-154.
    • (2008) Hum Genet , vol.124 , pp. 147-154
    • Keene, K.L.1    Mychaleckyj, J.C.2    Leak, T.S.3    Smith, S.G.4    Perlegas, P.S.5    Divers, J.6
  • 40
    • 12244264435 scopus 로고    scopus 로고
    • Genetic power calculator: Design of linkage and association genetic mapping studies of complex traits
    • DOI 10.1093/bioinformatics/19.1.149
    • Purcell S, Cherny SS, Sham PC. Genetic power calculator: design of linkage and association genetic mapping studies of complex traits. Bioinformatics 2003; 19: 149-150. (Pubitemid 36150192)
    • (2003) Bioinformatics , vol.19 , Issue.1 , pp. 149-150
    • Purcell, S.1    Cherny, S.S.2    Sham, P.C.3
  • 42
    • 22144458983 scopus 로고    scopus 로고
    • Neurotractin/kilon promotes neurite outgrowth and is expressed on reactive astrocytes after entorhinal cortex lesion
    • DOI 10.1016/j.mcn.2005.04.010, PII S1044743105000977
    • Schafer M, Brauer AU, Savaskan NE, Rathjen FG, Brummendorf T. Neurotractin/kilon promotes neurite outgrowth and is expressed on reactive astrocytes after entorhinal cortex lesion. Mol Cell Neurosci 2005; 29: 580-590. (Pubitemid 40984699)
    • (2005) Molecular and Cellular Neuroscience , vol.29 , Issue.4 , pp. 580-590
    • Schafer, M.1    Brauer, A.U.2    Savaskan, N.E.3    Rathjen, F.G.4    Brummendorf, T.5
  • 43
    • 49649114875 scopus 로고    scopus 로고
    • Transmembrane protein 18 enhances the tropism of neural stem cells for glioma cells
    • Jurvansuu J, Zhao Y, Leung DS, Boulaire J, Yu YH, Ahmed S et al. Transmembrane protein 18 enhances the tropism of neural stem cells for glioma cells. Cancer Res 2008; 68: 4614-4622.
    • (2008) Cancer Res , vol.68 , pp. 4614-4622
    • Jurvansuu, J.1    Zhao, Y.2    Leung, D.S.3    Boulaire, J.4    Yu, Y.H.5    Ahmed, S.6
  • 44
    • 33846853084 scopus 로고    scopus 로고
    • The SH2B gene is associated with serum leptin and body fat in normal female twins
    • Jamshidi Y, Snieder H, Ge D, Spector TD, O'Dell SD. The SH2B gene is associated with serum leptin and body fat in normal female twins. Obesity (Silver Spring) 2007; 15: 5-9. (Pubitemid 46219777)
    • (2007) Obesity , vol.15 , Issue.1 , pp. 5-9
    • Jamshidi, Y.1    Snieder, H.2    Ge, D.3    Spector, T.D.4    O'Dell, S.D.5
  • 47
    • 79551609852 scopus 로고    scopus 로고
    • Resequencing and analysis of variation in the TCF7L2 gene in African Americans suggests that SNP rs7903146 is the causal diabetes susceptibility variant
    • Palmer ND, Hester JM, An SS, Adeyemo A, Rotimi C, Langefeld CD et al. Resequencing and analysis of variation in the TCF7L2 gene in African Americans suggests that SNP rs7903146 is the causal diabetes susceptibility variant. Diabetes 2011; 60: 662-668.
    • (2011) Diabetes , vol.60 , pp. 662-668
    • Palmer, N.D.1    Hester, J.M.2    An, S.S.3    Adeyemo, A.4    Rotimi, C.5    Langefeld, C.D.6
  • 48
    • 58149348419 scopus 로고    scopus 로고
    • Genome-wide association studies: Implications for multiethnic samples
    • Cooper RS, Tayo B, Zhu X. Genome-wide association studies: implications for multiethnic samples. Hum Mol Genet 2008; 17: R151-R155.
    • (2008) Hum Mol Genet , vol.17
    • Cooper, R.S.1    Tayo, B.2    Zhu, X.3
  • 49
    • 2942675089 scopus 로고    scopus 로고
    • Race/ethnic issues in obesity and obesity-related comorbidities
    • DOI 10.1210/jc.2004-0339
    • Cossrow N, Falkner B. Race/ethnic issues in obesity and obesity-related comorbidities. J Clin Endocrinol Metab 2004; 89: 2590-2594. (Pubitemid 38766336)
    • (2004) Journal of Clinical Endocrinology and Metabolism , vol.89 , Issue.6 , pp. 2590-2594
    • Cossrow, N.1    Falkner, B.2
  • 50
    • 0038305833 scopus 로고    scopus 로고
    • Obesity, regional fat distribution, and syndrome X in obese black versus white adolescents: Race differential in diabetogenic and atherogenic risk factors
    • Bacha F, Saad R, Gungor N, Janosky J, Arslanian SA. Obesity, regional fat distribution, and syndrome X in obese black versus white adolescents: race differential in diabetogenic and atherogenic risk factors. J Clin Endocrinol Metab 2003; 88: 2534-2540. (Pubitemid 36724419)
    • (2003) Journal of Clinical Endocrinology and Metabolism , vol.88 , Issue.6 , pp. 2534-2540
    • Bacha, F.1    Saad, R.2    Gungor, N.3    Janosky, J.4    Arslanian, S.A.5


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