CDH13 Gene coding T-cadherin influences variations in plasma adiponectin levels in the Japanese population

Human Mutation

Volumn 33, Issue 2, 2012, Pages 402-410

  Morisaki, Hiroko ^a   Yamanaka, Itaru ^a   Iwai, Naoharu ^a   Miyamoto, Yoshihiro ^a   Kokubo, Yoshihiro ^a   Okamura, Tomonori ^a   Okayama, Akira ^a   Morisaki, Takayuki ^a,b  

^a NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

^b OSAKA UNIVERSITY   (Japan)

Author keywords

Adiponectin; Cdh13; Gwas; SNP

Indexed keywords

ADIPONECTIN; CADHERIN; T CADHERIN; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; FEMALE; GENETIC ASSOCIATION; GENETIC LINKAGE; GENETIC VARIABILITY; GLUCOSE METABOLISM; HUMAN; INTRON; JAPAN; JAPANESE; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROMOTER REGION; SINGLE NUCLEOTIDE POLYMORPHISM;

ADIPONECTIN; ADULT; AGED; AGED, 80 AND OVER; ASIAN CONTINENTAL ANCESTRY GROUP; CADHERINS; FEMALE; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HUMANS; JAPAN; LINKAGE DISEQUILIBRIUM; MALE; MIDDLE AGED; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 84857533640     PISSN: 10597794     EISSN: 10981004     Source Type: Journal    
DOI: 10.1002/humu.21652     Document Type: Article

References (27)

1. Heng D, Ma S, Lee JJ, Tai BC, Mak KH, Hughes K, Chew SK, Chia KS, Tan CE, Tai ES. 2006.Modification of theNCEP ATP III definitions of themetabolic syndrome for use in Asians identifies individuals at risk of ischemic heart disease. Atherosclerosis 186:367-373.
2. Hotta K, Funahashi T, Arita Y, Takahashi M, Matsuda M, Okamoto Y, Iwahashi H, Kuriyama H, Ouchi N, Maeda K, Nishida M, Kihara S, Sakai N, Nakajima T, Hasegawa K, Muraguchi M, Ohmoto Y, Nakamura T, Yamashita S, Hanafusa T, Matsuzawa Y. 2000. Plasma concentrations of a novel, adiposespecific protein, adiponectin, in type 2 diabetic patients. Arterioscler Thromb Vasc Biol 20:1595-1599.
3. Hug C, Wang J, Ahmad NS, Bogan JS, Tsao TS, Lodish HF. 2004. T-cadherin is a receptor for hexameric and high-molecular-weight forms of Acrp30/adiponectin. Proc Natl Acad Sci USA 101:10308-10313.
4. Iwai N, Katsuya T, Mannami T, Higaki J, Ogihara T, Kokame K, Ogata J, Baba S. 2002. Association between SAH, an acyl-CoAsynthetase gene, and hypertriglyceridemia, obesity, and hypertension. Circulation 105:41-47.
5. Jee SH, Sull JW, Lee JE, ShinC, Park J, KimmH, ChoEY, ShinES, Yun JE, Park JW, Kim SY, Lee SJ, Jee EJ, Baik I, Kao L, Yoon SK, Jang Y, Beaty TH. 2010. Adiponectin concentrations: a genome-wide association study. Am J Hum Genet 87:545-552.
6. Kadowaki T, Sekikawa A, Okamura T, Takamiya T, Kashiwagi A, Zaky WR, Maegawa H, El-Saed A, Nakamura Y, Evans RW, Edmundowicz D, Kita Y, Kuller LH, Ueshima H. 2006. Higher levels of adiponectin in American than in Japanese men despite obesity. Metabolism 55:1561-1563.
7. Kanazawa M, Yoshiike N, Osaka T, Numba Y, Zimmet P, Inoue S. 2002. Criteria and classification of obesity in Japan and Asia-Oceania. Asia Pac J Clin Nutr 11(Suppl 8):S732-S737.
8. Kern PA, Di Gregorio GB, Lu T, RassouliN, Ranganathan G. 2003. Adiponectin expression from human adipose tissue: relation to obesity, insulin resistance, and tumor necrosis factor-alpha expression. Diabetes 52:1779-1785.
9. Kitta Y, Takano H, Nakamura T, Kodama Y, Umetani K, Fujioka D, Saito Y, Kawabata K, Obata JE, Mende A, Kobayashi T, Kugiyama K. 2008. Low adiponectin levels predict late in-stent restenosis after baremetal stenting in native coronary arteries. Int J Cardiol 131:78-82.
10. Lara-Castro C, Luo N, Wallace P, Klein RL, GarveyWT. 2006. Adiponectinmultimeric complexes and the metabolic syndrome trait cluster. Diabetes 55:249-259.
11. Lindsay RS, Funahashi T, Hanson RL, Matsuzawa Y, Tanaka S, Tataranni PA, Knowler WC, Krakoff J. 2002. Adiponectin and development of type 2 diabetes in the Pima Indian population. Lancet 360:57-58.
12. Ling H, Waterworth DM, Stirnadel HA, Pollin TI, Barter PJ, Kesäniemi YA, Mahley RW, McPherson R, Waeber G, Bersot TP, Cohen JC, Grundy SM, Mooser VE, Mitchell BD. 2009. Genome-wide linkage and association analyses to identify genes influencing adiponectin levels: the GEMS Study. Obesity 17:737-744.
13. Maeda K, Okubo K, Shimomura I, Funahashi T, Matsuzawa Y, Matsubara K. 1996. cDNA cloning and expression of a novel adipose specific collagen-like factor, apM1(AdiPoseMost abundant Gene transcript 1).BiochemBiophysResCommun 221:286-289.
14. Martin LJ, Woo JG, Daniels SR, Goodman E, Dolan LM. 2005. The relationships of adiponectin with insulin and lipids are strengthened with increasing adiposity. J Clin Endocrinol Metab 90:4255-4259.
15. Matsuzawa Y, Funahashi T, Kihara S, Shimomura I. 2004. Adiponectin and metabolic syndrome. Arterioscler Thromb Vasc Biol 24:29-33.
16. Menzaghi C, Trischitta V, Doria A. 2007. Genetic influences of adiponectin on insulin resistance, type 2 diabetes, and cardiovascular disease. Diabetes 56:1198-1209.
17. Moldoveanu E, Mut-Vitcu B, Tanaseanu GR, Marta DS, Manea G, Kosaka T, Vidulescu C, Tanaseanu C. 2008. Low basal levels of circulating adiponectin in patients undergoing coronary stenting predict in-stent restenosis, independently of basal levels of inflammatory markers: lipoprotein associated phospholipase A2, and myeloperoxidase. Clin Biochem 41:1429-1433.
18. Ntalla I, Dedoussis G, Yannakoulia M, Smart MC, Louizou E, Sakka SD, Papoutsakis C, Talmud PJ. 2009. ADIPOQ gene polymorphism rs1501299 interacts with fibre intake to affect adiponectin concentration in children: the GENe-Diet Attica Investigation on childhood obesity. Eur J Nutr 48:493-497.
19. Pischon T, Girman CJ, Hotamisligil GS, Rifai N, Hu FB, Rimm EB. 2004. Plasma adiponectin levels and risk of myocardial infarction in men. JAMA. 291:1730-1737.
20. Resink TJ, Kuzmenko YS, Kern F, Stambolsky D, Bochkov VN, Tkachuk VA, Erne P, Niermann T. 1999. LDL binds to surface-expressed human T-cadherin in transfected HEK293 cells and influences homophilic adhesive interactions. FEBS Lett 1463:29-34.
21. Richards JB, Waterworth D, O'Rahilly S, Hivert MF, Loos RJ, Perry JR, Tanaka T, Timpson NJ, Semple RK, Soranzo N, Song K, Rocha N, Grundberg E, Dupuis J, Florez JC, LangenbergC, Prokopenko I, SaxenaR, SladekR, AulchenkoY, EvansD, Waeber G, Erdmann J, Burnett MS, Sattar N, Devaney J, Willenborg C, Hingorani A, Witteman JC, Vollenweider P, Glaser B, Hengstenberg C, Ferrucci L, Melzer D, Stark K, Deanfield J, Winogradow J, Grassl M, Hall AS, Egan JM, Thompson JR, Ricketts SL, König IR, Reinhard W, Grundy S, Wichmann HE, Barter P, Mahley R, Kesaniemi YA, Rader DJ, Reilly MP, Epstein SE, Stewart AF, Van Duijn CM, Schunkert H, Burling K, Deloukas P, Pastinen T, Samani NJ, McPherson R, Davey Smith G, Frayling TM, Wareham NJ, Meigs JB, Mooser V, Spector TD; GIANT Consortium. 2009. A genome-wide association study reveals variants in ARL15 that influence adiponectin levels. PLoS Genet 5:e1000768.
22. Santaniemi M, Kesäniemi YA, Ukkola O. 2006. Low plasma adiponectin concentration is an indicator of the metabolic syndrome. Eur J Endocrinol 155:745-750.
23. Snehalatha C, Mukesh B, Simon M, Viswanathan V, Haffner SM, Ramachandran A. 2003. Plasma adiponectin is an independent predictor of type 2 diabetes in Asian Indians. Diabetes Care 26:3226-3229.
24. Wu Y, Li Y, Lange EM, Croteau-Chonka DC, Kuzawa CW, McDade TW, Qin L, Curocichin G, Borja JB, Lange LA, Adair LS, Mohlke KL. 2010. Genome-wide association study for adiponectin levels in Filipino women identifies CDH13 and a novel uncommonhaplotype at KNG1-ADIPOQ. HumMol Genet 19:4955-4964.
25. YamauchiT, Kamon J, WakiH, Terauchi Y, KubotaN, HaraK, Mori Y, IdeT, Murakami K, Tsuboyama-Kasaoka N, Ezaki O, Akanuma Y, Gavrilova O, Vinson C, Reitman ML, Kagechika H, Shudo K, Yoda M, Nakano Y, Tobe K, Nagai R, Kimura S, Tomita M, Froguel P, Kadowaki T. 2001. The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity. Nat Med 7:941-946.
26. YangWS, Chuang LM. 2006.Humangenetics of adiponectin inthe metabolic syndrome. J Mol Me 84:112-121.
27. Yu YH, Ginsberg HN. 2005. Adipocyte signaling and lipid homeostasis: sequelae of insulin-resistant adipose tissue. Circ Res 96:1042-1052.