-
1
-
-
0032518374
-
A mechanism for all polymerases
-
[CrossRef] [PubMed]
-
Steitz, T.A. A mechanism for all polymerases. Nature 1998, 391, 231-232. [CrossRef] [PubMed]
-
(1998)
Nature
, vol.391
, pp. 231-232
-
-
Steitz, T.A.1
-
2
-
-
32344432085
-
A comparison of viral RNA-dependent RNA polymerases
-
[CrossRef] [PubMed]
-
Ferrer-Orta, C.; Arias, A.; Escarmis, C.; Verdaguer, N. A comparison of viral RNA-dependent RNA polymerases. Curr. Opin. Struct. Biol. 2006, 16, 27-34. [CrossRef] [PubMed]
-
(2006)
Curr. Opin. Struct. Biol
, vol.16
, pp. 27-34
-
-
Ferrer-Orta, C.1
Arias, A.2
Escarmis, C.3
Verdaguer, N.4
-
3
-
-
40649100793
-
Structure-function relationships among RNA-dependent RNA polymerases
-
[PubMed]
-
Ng, K.K.; Arnold, J.J.; Cameron, C.E. Structure-function relationships among RNA-dependent RNA polymerases. Curr. Top. Microbiol. Immunol. 2008, 320, 137-156. [PubMed]
-
(2008)
Curr. Top. Microbiol. Immunol
, vol.320
, pp. 137-156
-
-
Ng, K.K.1
Arnold, J.J.2
Cameron, C.E.3
-
4
-
-
79960384228
-
The making of a picornavirus genome
-
Ehrenfeld, E., Domingo, E., Ross, R.P., Eds.; ASM Press: Washington, DC, USA
-
Wimmer, E.; Paul, A.V. The making of a picornavirus genome. In The Picornavirus; Ehrenfeld, E., Domingo, E., Ross, R.P., Eds.; ASM Press: Washington, DC, USA, 2010; pp. 33-55.
-
(2010)
The Picornavirus
, pp. 33-55
-
-
Wimmer, E.1
Paul, A.V.2
-
5
-
-
4644238112
-
Structural basis for proteolysis-dependent activation of the poliovirus RNA-dependent RNA polymerase
-
[CrossRef] [PubMed]
-
Thompson, A.A.; Peersen, O.B. Structural basis for proteolysis-dependent activation of the poliovirus RNA-dependent RNA polymerase. EMBO J. 2004, 23, 3462-3471. [CrossRef] [PubMed]
-
(2004)
EMBO J
, vol.23
, pp. 3462-3471
-
-
Thompson, A.A.1
Peersen, O.B.2
-
6
-
-
84877307801
-
Structures of coxsackievirus, rhinovirus, and poliovirus polymerase elongation complexes solved by engineering RNA mediated crystal contacts
-
[CrossRef] [PubMed]
-
Gong, P.; Kortus, M.G.; Nix, J.C.; Davis, R.E.; Peersen, O.B. Structures of coxsackievirus, rhinovirus, and poliovirus polymerase elongation complexes solved by engineering RNA mediated crystal contacts. PLoS ONE 2013, 8, e60272. [CrossRef] [PubMed]
-
(2013)
PLoS ONE
, vol.8
-
-
Gong, P.1
Kortus, M.G.2
Nix, J.C.3
Davis, R.E.4
Peersen, O.B.5
-
7
-
-
78651097570
-
Structural basis for active site closure by the poliovirus RNA-dependent RNA polymerase
-
[CrossRef] [PubMed]
-
Gong, P.; Peersen, O.B. Structural basis for active site closure by the poliovirus RNA-dependent RNA polymerase. Proc. Natl. Acad. Sci. USA 2010, 107, 22505-22510. [CrossRef] [PubMed]
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 22505-22510
-
-
Gong, P.1
Peersen, O.B.2
-
8
-
-
52649173300
-
The crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase in complex with its protein primer VPg confirms the existence of a second VPg binding site on Picornaviridae polymerases
-
[CrossRef] [PubMed]
-
Gruez, A.; Selisko, B.; Roberts, M.; Bricogne, G.; Bussetta, C.; Jabafi, I.; Coutard, B.; de Palma, A.M.; Neyts, J.; Canard, B. The crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase in complex with its protein primer VPg confirms the existence of a second VPg binding site on Picornaviridae polymerases. J. Virol. 2008, 82, 9577-9590. [CrossRef] [PubMed]
-
(2008)
J. Virol
, vol.82
, pp. 9577-9590
-
-
Gruez, A.1
Selisko, B.2
Roberts, M.3
Bricogne, G.4
Bussetta, C.5
Jabafi, I.6
Coutard, B.7
de Palma, A.M.8
Neyts, J.9
Canard, B.10
-
9
-
-
52649143257
-
polhighlights the functional importance of residue 5 in picornavirus polymerases
-
[CrossRef] [PubMed]
-
polhighlights the functional importance of residue 5 in picornavirus polymerases. J. Virol. 2008, 82, 9458-9464. [CrossRef] [PubMed]
-
(2008)
J. Virol
, vol.82
, pp. 9458-9464
-
-
Campagnola, G.1
Weygandt, M.2
Scoggin, K.3
Peersen, O.4
-
10
-
-
79952537148
-
Structures of EV71 RNA-dependent RNA polymerase in complex with substrate and analogue provide a drug target against the hand-foot-and-mouth disease pandemic in China
-
[CrossRef] [PubMed]
-
Wu, Y.; Lou, Z.; Miao, Y.; Yu, Y.; Dong, H.; Peng, W.; Bartlam, M.; Li, X.; Rao, Z. Structures of EV71 RNA-dependent RNA polymerase in complex with substrate and analogue provide a drug target against the hand-foot-and-mouth disease pandemic in China. Protein Cell 2010, 1, 491-500. [CrossRef] [PubMed]
-
(2010)
Protein Cell
, vol.1
, pp. 491-500
-
-
Wu, Y.1
Lou, Z.2
Miao, Y.3
Yu, Y.4
Dong, H.5
Peng, W.6
Bartlam, M.7
Li, X.8
Rao, Z.9
-
11
-
-
4143147318
-
The crystal structure of the RNA-dependent RNA polymerase from human rhinovirus: A dual function target for common cold antiviral therapy
-
[CrossRef] [PubMed]
-
Love, R.A.; Maegley, K.A.; Yu, X.; Ferre, R.A.; Lingardo, L.K.; Diehl, W.; Parge, H.E.; Dragovich, P.S.; Fuhrman, S.A. The crystal structure of the RNA-dependent RNA polymerase from human rhinovirus: A dual function target for common cold antiviral therapy. Structure 2004, 12, 1533-1544. [CrossRef] [PubMed]
-
(2004)
Structure
, vol.12
, pp. 1533-1544
-
-
Love, R.A.1
Maegley, K.A.2
Yu, X.3
Ferre, R.A.4
Lingardo, L.K.5
Diehl, W.6
Parge, H.E.7
Dragovich, P.S.8
Fuhrman, S.A.9
-
12
-
-
10644250663
-
Crystal structure of complete rhinovirus RNA polymerase suggests front loading of protein primer
-
[CrossRef] [PubMed]
-
Appleby, T.C.; Luecke, H.; Shim, J.H.; Wu, J.Z.; Cheney, I.W.; Zhong, W.; Vogeley, L.; Hong, Z.; Yao, N. Crystal structure of complete rhinovirus RNA polymerase suggests front loading of protein primer. J. Virol. 2005, 79, 277-288. [CrossRef] [PubMed]
-
(2005)
J. Virol
, vol.79
, pp. 277-288
-
-
Appleby, T.C.1
Luecke, H.2
Shim, J.H.3
Wu, J.Z.4
Cheney, I.W.5
Zhong, W.6
Vogeley, L.7
Hong, Z.8
Yao, N.9
-
13
-
-
33644519317
-
The structure of a protein primer-polymerase complex in the initiation of genome replication
-
[CrossRef] [PubMed]
-
Ferrer-Orta, C.; Arias, A.; Agudo, R.; Perez-Luque, R.; Escarmis, C.; Domingo, E.; Verdaguer, N. The structure of a protein primer-polymerase complex in the initiation of genome replication. EMBO J. 2006, 25, 880-888. [CrossRef] [PubMed]
-
(2006)
EMBO J
, vol.25
, pp. 880-888
-
-
Ferrer-Orta, C.1
Arias, A.2
Agudo, R.3
Perez-Luque, R.4
Escarmis, C.5
Domingo, E.6
Verdaguer, N.7
-
14
-
-
8744222695
-
Structure of foot-and-mouth disease virus RNA-dependent RNA polymerase and its complex with a template-primer RNA
-
[CrossRef] [PubMed]
-
Ferrer-Orta, C.; Arias, A.; Perez-Luque, R.; Escarmis, C.; Domingo, E.; Verdaguer, N. Structure of foot-and-mouth disease virus RNA-dependent RNA polymerase and its complex with a template-primer RNA. J. Biol. Chem. 2004, 279, 47212-47221. [CrossRef] [PubMed]
-
(2004)
J. Biol. Chem
, vol.279
, pp. 47212-47221
-
-
Ferrer-Orta, C.1
Arias, A.2
Perez-Luque, R.3
Escarmis, C.4
Domingo, E.5
Verdaguer, N.6
-
15
-
-
34547178347
-
Sequential structures provide insights into the fidelity of RNA replication
-
[CrossRef] [PubMed]
-
Ferrer-Orta, C.; Arias, A.; Perez-Luque, R.; Escarmis, C.; Domingo, E.; Verdaguer, N. Sequential structures provide insights into the fidelity of RNA replication. Proc. Natl. Acad. Sci. USA 2007, 104, 9463-9468. [CrossRef] [PubMed]
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 9463-9468
-
-
Ferrer-Orta, C.1
Arias, A.2
Perez-Luque, R.3
Escarmis, C.4
Domingo, E.5
Verdaguer, N.6
-
16
-
-
84872021142
-
What is the role of motif D in the nucleotide incorporation catalyzed by the RNA-dependent RNA polymerase from poliovirus? PLoS Comput
-
[CrossRef] [PubMed]
-
Shen, H.; Sun, H.; Li, G. What is the role of motif D in the nucleotide incorporation catalyzed by the RNA-dependent RNA polymerase from poliovirus? PLoS Comput. Biol. 2012, 8, e1002851. [CrossRef] [PubMed]
-
(2012)
Biol
, vol.8
-
-
Shen, H.1
Sun, H.2
Li, G.3
-
17
-
-
0038809107
-
A single mutation in poliovirus RNA-dependent RNA polymerase confers resistance to mutagenic nucleotide analogs via increased fidelity
-
[CrossRef] [PubMed]
-
Pfeiffer, J.K.; Kirkegaard, K. A single mutation in poliovirus RNA-dependent RNA polymerase confers resistance to mutagenic nucleotide analogs via increased fidelity. Proc. Natl. Acad. Sci. USA 2003, 100, 7289-7294. [CrossRef] [PubMed]
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 7289-7294
-
-
Pfeiffer, J.K.1
Kirkegaard, K.2
-
18
-
-
21844431621
-
Remote site control of an active site fidelity checkpoint in a viral RNA-dependent RNA polymerase
-
[CrossRef] [PubMed]
-
Arnold, J.J.; Vignuzzi, M.; Stone, J.K.; Andino, R.; Cameron, C.E. Remote site control of an active site fidelity checkpoint in a viral RNA-dependent RNA polymerase. J. Biol. Chem. 2005, 280, 25706-25716. [CrossRef] [PubMed]
-
(2005)
J. Biol. Chem
, vol.280
, pp. 25706-25716
-
-
Arnold, J.J.1
Vignuzzi, M.2
Stone, J.K.3
Andino, R.4
Cameron, C.E.5
-
19
-
-
77958122066
-
A multi-step process of viral adaptation to a mutagenic nucleoside analogue by modulation of transition types leads to extinction-escape
-
[CrossRef] [PubMed]
-
Agudo, R.; Ferrer-Orta, C.; Arias, A.; de la Higuera, I.; Perales, C.; Perez-Luque, R.; Verdaguer, N.; Domingo, E. A multi-step process of viral adaptation to a mutagenic nucleoside analogue by modulation of transition types leads to extinction-escape. PLoS Pathog. 2010, 6, e1001072. [CrossRef] [PubMed]
-
(2010)
PLoS Pathog
, vol.6
-
-
Agudo, R.1
Ferrer-Orta, C.2
Arias, A.3
de la Higuera, I.4
Perales, C.5
Perez-Luque, R.6
Verdaguer, N.7
Domingo, E.8
-
20
-
-
33947386595
-
Crystal structure of poliovirus 3CD protein: Virally encoded protease and precursor to the RNA-dependent RNA polymerase
-
[CrossRef] [PubMed]
-
Marcotte, L.L.; Wass, A.B.; Gohara, D.W.; Pathak, H.B.; Arnold, J.J.; Filman, D.J.; Cameron, C.E.; Hogle, J.M. Crystal structure of poliovirus 3CD protein: Virally encoded protease and precursor to the RNA-dependent RNA polymerase. J. Virol. 2007, 81, 3583-3596. [CrossRef] [PubMed]
-
(2007)
J. Virol
, vol.81
, pp. 3583-3596
-
-
Marcotte, L.L.1
Wass, A.B.2
Gohara, D.W.3
Pathak, H.B.4
Arnold, J.J.5
Filman, D.J.6
Cameron, C.E.7
Hogle, J.M.8
-
21
-
-
77952710653
-
Structure of foot-and-mouth disease virus mutant polymerases with reduced sensitivity to ribavirin
-
[CrossRef] [PubMed]
-
Ferrer-Orta, C.; Sierra, M.; Agudo, R.; de la Higuera, I.; Arias, A.; Perez-Luque, R.; Escarmis, C.; Domingo, E.; Verdaguer, N. Structure of foot-and-mouth disease virus mutant polymerases with reduced sensitivity to ribavirin. J. Virol. 2010, 84, 6188-6199. [CrossRef] [PubMed]
-
(2010)
J. Virol
, vol.84
, pp. 6188-6199
-
-
Ferrer-Orta, C.1
Sierra, M.2
Agudo, R.3
de la Higuera, I.4
Arias, A.5
Perez-Luque, R.6
Escarmis, C.7
Domingo, E.8
Verdaguer, N.9
-
22
-
-
79958744018
-
Molecular dynamics simulations of viral RNA polymerases link conserved and correlated motions of functional elements to fidelity
-
[CrossRef] [PubMed]
-
Moustafa, I.M.; Shen, H.; Morton, B.; Colina, C.M.; Cameron, C.E. Molecular dynamics simulations of viral RNA polymerases link conserved and correlated motions of functional elements to fidelity. J. Mol. Biol. 2011, 410, 159-181. [CrossRef] [PubMed]
-
(2011)
J. Mol. Biol
, vol.410
, pp. 159-181
-
-
Moustafa, I.M.1
Shen, H.2
Morton, B.3
Colina, C.M.4
Cameron, C.E.5
-
23
-
-
2442677715
-
Initiation of viral RNA-dependent RNA polymerization
-
[CrossRef] [PubMed]
-
Van Dijk, A.A.; Makeyev, E.V.; Bamford, D.H. Initiation of viral RNA-dependent RNA polymerization. J. Gen. Virol. 2004, 85, 1077-1093. [CrossRef] [PubMed]
-
(2004)
J. Gen. Virol
, vol.85
, pp. 1077-1093
-
-
Van Dijk, A.A.1
Makeyev, E.V.2
Bamford, D.H.3
-
24
-
-
70549094435
-
RNA-dependent RNA polymerases from Flaviviridae
-
[CrossRef] [PubMed]
-
Choi, K.H.; Rossmann, M.G. RNA-dependent RNA polymerases from Flaviviridae. Curr. Opin. Struct. Biol. 2009, 19, 746-751. [CrossRef] [PubMed]
-
(2009)
Curr. Opin. Struct. Biol
, vol.19
, pp. 746-751
-
-
Choi, K.H.1
Rossmann, M.G.2
-
25
-
-
70549097351
-
RNA-dependent RNA polymerases from flaviviruses and Picornaviridae
-
[CrossRef] [PubMed]
-
Lescar, J.; Canard, B. RNA-dependent RNA polymerases from flaviviruses and Picornaviridae. Curr. Opin. Struct. Biol. 2009, 19, 759-767. [CrossRef] [PubMed]
-
(2009)
Curr. Opin. Struct. Biol
, vol.19
, pp. 759-767
-
-
Lescar, J.1
Canard, B.2
-
26
-
-
0035826258
-
A mechanism for initiating RNA-dependent RNA polymerization
-
[CrossRef] [PubMed]
-
Butcher, S.J.; Grimes, J.M.; Makeyev, E.V.; Bamford, D.H.; Stuart, D.I. A mechanism for initiating RNA-dependent RNA polymerization. Nature 2001, 410, 235-240. [CrossRef] [PubMed]
-
(2001)
Nature
, vol.410
, pp. 235-240
-
-
Butcher, S.J.1
Grimes, J.M.2
Makeyev, E.V.3
Bamford, D.H.4
Stuart, D.I.5
-
27
-
-
84864011029
-
Structure of hepatitis C virus polymerase in complex with primer-template RNA
-
[CrossRef] [PubMed]
-
Mosley, R.T.; Edwards, T.E.; Murakami, E.; Lam, A.M.; Grice, R.L.; Du, J.; Sofia, M.J.; Furman, P.A.; Otto, M.J. Structure of hepatitis C virus polymerase in complex with primer-template RNA. J. Virol. 2012, 86, 6503-6511. [CrossRef] [PubMed]
-
(2012)
J. Virol
, vol.86
, pp. 6503-6511
-
-
Mosley, R.T.1
Edwards, T.E.2
Murakami, E.3
Lam, A.M.4
Grice, R.L.5
Du, J.6
Sofia, M.J.7
Furman, P.A.8
Otto, M.J.9
-
28
-
-
84923103825
-
Viral replication
-
[CrossRef] [PubMed]
-
Appleby, T.C.; Perry, J.K.; Murakami, E.; Barauskas, O.; Feng, J.; Cho, A.; Fox, D., 3rd; Wetmore, D.R.; McGrath, M.E.; Ray, A.S.; et al. Viral replication. Structural basis for RNA replication by the hepatitis C virus polymerase. Science 2015, 347, 771-775. [CrossRef] [PubMed]
-
(2015)
Structural basis for RNA replication by the hepatitis C virus polymerase. Science
, vol.347
, pp. 771-775
-
-
Appleby, T.C.1
Perry, J.K.2
Murakami, E.3
Barauskas, O.4
Feng, J.5
Cho, A.6
Fox, D.7
Wetmore, D.R.8
McGrath, M.E.9
Ray, A.S.10
-
29
-
-
70549097349
-
Structural insights into replication initiation and elongation processes by the FMDV RNA-dependent RNA polymerase
-
[CrossRef] [PubMed]
-
Ferrer-Orta, C.; Agudo, R.; Domingo, E.; Verdaguer, N. Structural insights into replication initiation and elongation processes by the FMDV RNA-dependent RNA polymerase. Curr. Opin. Struct. Biol. 2009, 19, 752-758. [CrossRef] [PubMed]
-
(2009)
Curr. Opin. Struct. Biol
, vol.19
, pp. 752-758
-
-
Ferrer-Orta, C.1
Agudo, R.2
Domingo, E.3
Verdaguer, N.4
-
30
-
-
0032554886
-
Protein-primed RNA synthesis by purified poliovirus RNA polymerase
-
[CrossRef] [PubMed]
-
Paul, A.V.; van Boom, J.H.; Filippov, D.; Wimmer, E. Protein-primed RNA synthesis by purified poliovirus RNA polymerase. Nature 1998, 393, 280-284. [CrossRef] [PubMed]
-
(1998)
Nature
, vol.393
, pp. 280-284
-
-
Paul, A.V.1
van Boom, J.H.2
Filippov, D.3
Wimmer, E.4
-
31
-
-
84931568245
-
Initiation of protein-primed picornavirus RNA synthesis
-
[CrossRef] [PubMed]
-
Paul, A.V.; Wimmer, E. Initiation of protein-primed picornavirus RNA synthesis. Virus Res. 2015, 206, 12-26. [CrossRef] [PubMed]
-
(2015)
Virus Res
, vol.206
, pp. 12-26
-
-
Paul, A.V.1
Wimmer, E.2
-
32
-
-
81755166311
-
The genome-linked protein VPg of vertebrate viruses-A multifaceted protein
-
[CrossRef] [PubMed]
-
Goodfellow, I. The genome-linked protein VPg of vertebrate viruses-A multifaceted protein. Curr. Opin. Virol. 2011, 1, 355-362. [CrossRef] [PubMed]
-
(2011)
Curr. Opin. Virol
, vol.1
, pp. 355-362
-
-
Goodfellow, I.1
-
33
-
-
0037013317
-
Similar structural basis for membrane localization and protein priming by an RNA-dependent RNA polymerase
-
[CrossRef] [PubMed]
-
Lyle, J.M.; Clewell, A.; Richmond, K.; Richards, O.C.; Hope, D.A.; Schultz, S.C.; Kirkegaard, K. Similar structural basis for membrane localization and protein priming by an RNA-dependent RNA polymerase. J. Biol. Chem. 2002, 277, 16324-16331. [CrossRef] [PubMed]
-
(2002)
J. Biol. Chem
, vol.277
, pp. 16324-16331
-
-
Lyle, J.M.1
Clewell, A.2
Richmond, K.3
Richards, O.C.4
Hope, D.A.5
Schultz, S.C.6
Kirkegaard, K.7
-
34
-
-
84877616491
-
Crystal structure of enterovirus 71 RNA-dependent RNA polymerase complexed with its protein primer VPg: Implication for a trans mechanism of VPg uridylylation
-
[CrossRef] [PubMed]
-
Chen, C.; Wang, Y.; Shan, C.; Sun, Y.; Xu, P.; Zhou, H.; Yang, C.; Shi, P.Y.; Rao, Z.; Zhang, B.; et al. Crystal structure of enterovirus 71 RNA-dependent RNA polymerase complexed with its protein primer VPg: Implication for a trans mechanism of VPg uridylylation. J. Virol. 2013, 87, 5755-5768. [CrossRef] [PubMed]
-
(2013)
J. Virol
, vol.87
, pp. 5755-5768
-
-
Chen, C.1
Wang, Y.2
Shan, C.3
Sun, Y.4
Xu, P.5
Zhou, H.6
Yang, C.7
Shi, P.Y.8
Rao, Z.9
Zhang, B.10
-
35
-
-
0020491230
-
A tandem repeat gene in a picornavirus
-
[CrossRef] [PubMed]
-
Forss, S.; Schaller, H. A tandem repeat gene in a picornavirus. Nucleic Acids Res. 1982, 10, 6441-6450. [CrossRef] [PubMed]
-
(1982)
Nucleic Acids Res
, vol.10
, pp. 6441-6450
-
-
Forss, S.1
Schaller, H.2
-
36
-
-
0018827691
-
Heterogeneity of the genome-linked protein of foot-and-mouth disease virus
-
[PubMed]
-
King, A.M.; Sangar, D.V.; Harris, T.J.; Brown, F. Heterogeneity of the genome-linked protein of foot-and-mouth disease virus. J. Virol. 1980, 34, 627-634. [PubMed]
-
(1980)
J. Virol
, vol.34
, pp. 627-634
-
-
King, A.M.1
Sangar, D.V.2
Harris, T.J.3
Brown, F.4
-
37
-
-
0026591750
-
VPg gene amplification correlates with infective particle formation in foot-and-mouth disease virus
-
[PubMed]
-
Falk, M.M.; Sobrino, F.; Beck, E. VPg gene amplification correlates with infective particle formation in foot-and-mouth disease virus. J. Virol. 1992, 66, 2251-2260. [PubMed]
-
(1992)
J. Virol
, vol.66
, pp. 2251-2260
-
-
Falk, M.M.1
Sobrino, F.2
Beck, E.3
-
38
-
-
0344736921
-
Role of nonstructural proteins 3A and 3B in host range and pathogenicity of foot-and-mouth disease virus
-
[CrossRef] [PubMed]
-
Pacheco, J.M.; Henry, T.M.; O'Donnell, V.K.; Gregory, J.B.; Mason, P.W. Role of nonstructural proteins 3A and 3B in host range and pathogenicity of foot-and-mouth disease virus. J. Virol. 2003, 77, 13017-13027. [CrossRef] [PubMed]
-
(2003)
J. Virol
, vol.77
, pp. 13017-13027
-
-
Pacheco, J.M.1
Henry, T.M.2
O'Donnell, V.K.3
Gregory, J.B.4
Mason, P.W.5
-
39
-
-
35148863041
-
Genetic and phenotypic variation of foot-and-mouth disease virus during serial passages in a natural host
-
[CrossRef] [PubMed]
-
Carrillo, C.; Lu, Z.; Borca, M.V.; Vagnozzi, A.; Kutish, G.F.; Rock, D.L. Genetic and phenotypic variation of foot-and-mouth disease virus during serial passages in a natural host. J. Virol. 2007, 81, 11341-11351. [CrossRef] [PubMed]
-
(2007)
J. Virol
, vol.81
, pp. 11341-11351
-
-
Carrillo, C.1
Lu, Z.2
Borca, M.V.3
Vagnozzi, A.4
Kutish, G.F.5
Rock, D.L.6
-
40
-
-
0016658566
-
Temperature-sensitive mutants of foot-and-mouth disease virus: The isolation of mutants and observations on their properties and genetic recombination
-
[CrossRef] [PubMed]
-
MacKenzie, J.S.; Slade, W.R.; Lake, J.; Priston, R.A.; Bisby, J.; Laing, S.; Newman, J. Temperature-sensitive mutants of foot-and-mouth disease virus: The isolation of mutants and observations on their properties and genetic recombination. J. Gen. Virol. 1975, 27, 61-70. [CrossRef] [PubMed]
-
(1975)
J. Gen. Virol
, vol.27
, pp. 61-70
-
-
MacKenzie, J.S.1
Slade, W.R.2
Lake, J.3
Priston, R.A.4
Bisby, J.5
Laing, S.6
Newman, J.7
-
41
-
-
34447517120
-
Structure-function relationships of the viral RNA-dependent RNA polymerase: Fidelity, replication speed, and initiation mechanism determined by a residue in the ribose-binding pocket
-
[CrossRef] [PubMed]
-
Korneeva, V.S.; Cameron, C.E. Structure-function relationships of the viral RNA-dependent RNA polymerase: Fidelity, replication speed, and initiation mechanism determined by a residue in the ribose-binding pocket. J. Biol. Chem. 2007, 282, 16135-16145. [CrossRef] [PubMed]
-
(2007)
J. Biol. Chem
, vol.282
, pp. 16135-16145
-
-
Korneeva, V.S.1
Cameron, C.E.2
-
42
-
-
84870666504
-
Enterovirus 71 VPg uridylation uses a two-molecular mechanism of 3D polymerase
-
[CrossRef] [PubMed]
-
Sun, Y.; Wang, Y.; Shan, C.; Chen, C.; Xu, P.; Song, M.; Zhou, H.; Yang, C.; Xu, W.; Shi, P.Y.; et al. Enterovirus 71 VPg uridylation uses a two-molecular mechanism of 3D polymerase. J. Virol. 2012, 86, 13662-13671. [CrossRef] [PubMed]
-
(2012)
J. Virol
, vol.86
, pp. 13662-13671
-
-
Sun, Y.1
Wang, Y.2
Shan, C.3
Chen, C.4
Xu, P.5
Song, M.6
Zhou, H.7
Yang, C.8
Xu, W.9
Shi, P.Y.10
-
43
-
-
84907920692
-
Formation and working mechanism of the picornavirus VPg uridylylation complex
-
[CrossRef] [PubMed]
-
Sun, Y.; Guo, Y.; Lou, Z. Formation and working mechanism of the picornavirus VPg uridylylation complex. Curr. Opin. Virol. 2014, 9, 24-30. [CrossRef] [PubMed]
-
(2014)
Curr. Opin. Virol
, vol.9
, pp. 24-30
-
-
Sun, Y.1
Guo, Y.2
Lou, Z.3
-
44
-
-
67650688161
-
Mechanisms of DNA polymerases
-
[CrossRef] [PubMed]
-
Berdis, A.J. Mechanisms of DNA polymerases. Chem. Rev. 2009, 109, 2862-2879. [CrossRef] [PubMed]
-
(2009)
Chem. Rev
, vol.109
, pp. 2862-2879
-
-
Berdis, A.J.1
-
45
-
-
33747621427
-
Visualizing polynucleotide polymerase machines at work
-
[CrossRef] [PubMed]
-
Steitz, T.A. Visualizing polynucleotide polymerase machines at work. EMBO J. 2006, 25, 3458-3468. [CrossRef] [PubMed]
-
(2006)
EMBO J
, vol.25
, pp. 3458-3468
-
-
Steitz, T.A.1
-
46
-
-
34548801789
-
The molecular basis of eukaryotic transcription
-
[CrossRef] [PubMed]
-
Kornberg, R.D. The molecular basis of eukaryotic transcription. Proc. Natl. Acad. Sci. USA 2007, 104, 12955-12961. [CrossRef] [PubMed]
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 12955-12961
-
-
Kornberg, R.D.1
-
47
-
-
70549112913
-
The structural changes of T7 RNA polymerase from transcription initiation to elongation
-
[CrossRef] [PubMed]
-
Steitz, T.A. The structural changes of T7 RNA polymerase from transcription initiation to elongation. Curr. Opin. Struct. Biol. 2009, 19, 683-690. [CrossRef] [PubMed]
-
(2009)
Curr. Opin. Struct. Biol
, vol.19
, pp. 683-690
-
-
Steitz, T.A.1
-
48
-
-
43149087336
-
Structural insights into mechanisms of catalysis and inhibition in Norwalk virus polymerase
-
[CrossRef] [PubMed]
-
Zamyatkin, D.F.; Parra, F.; Alonso, J.M.; Harki, D.A.; Peterson, B.R.; Grochulski, P.; Ng, K.K. Structural insights into mechanisms of catalysis and inhibition in Norwalk virus polymerase. J. Biol. Chem. 2008, 283, 7705-7712. [CrossRef] [PubMed]
-
(2008)
J. Biol. Chem
, vol.283
, pp. 7705-7712
-
-
Zamyatkin, D.F.1
Parra, F.2
Alonso, J.M.3
Harki, D.A.4
Peterson, B.R.5
Grochulski, P.6
Ng, K.K.7
-
49
-
-
67349175999
-
Binding of 2ʹ-amino-2ʹ-deoxycytidine-5ʹ-triphosphate to norovirus polymerase induces rearrangement of the active site
-
[CrossRef] [PubMed]
-
Zamyatkin, D.F.; Parra, F.; Machin, A.; Grochulski, P.; Ng, K.K. Binding of 2ʹ-amino-2ʹ-deoxycytidine-5ʹ-triphosphate to norovirus polymerase induces rearrangement of the active site. J. Mol. Biol. 2009, 390, 10-16. [CrossRef] [PubMed]
-
(2009)
J. Mol. Biol
, vol.390
, pp. 10-16
-
-
Zamyatkin, D.F.1
Parra, F.2
Machin, A.3
Grochulski, P.4
Ng, K.K.5
-
50
-
-
84879074185
-
Role of motif B loop in allosteric regulation of RNA-dependent RNA polymerization activity
-
[CrossRef] [PubMed]
-
Garriga, D.; Ferrer-Orta, C.; Querol-Audi, J.; Oliva, B.; Verdaguer, N. Role of motif B loop in allosteric regulation of RNA-dependent RNA polymerization activity. J. Mol. Biol. 2013, 425, 2279-2287. [CrossRef] [PubMed]
-
(2013)
J. Mol. Biol
, vol.425
, pp. 2279-2287
-
-
Garriga, D.1
Ferrer-Orta, C.2
Querol-Audi, J.3
Oliva, B.4
Verdaguer, N.5
-
51
-
-
84895919460
-
Distinct conformations of a putative translocation element in poliovirus polymerase
-
[CrossRef] [PubMed]
-
Sholders, A.J.; Peersen, O.B. Distinct conformations of a putative translocation element in poliovirus polymerase. J. Mol. Biol. 2014, 426, 1407-1419. [CrossRef] [PubMed]
-
(2014)
J. Mol. Biol
, vol.426
, pp. 1407-1419
-
-
Sholders, A.J.1
Peersen, O.B.2
-
52
-
-
34248349170
-
Two proton transfers in the transition state for nucleotidyl transfer catalyzed by RNA-and DNA-dependent RNA and DNA polymerases
-
[CrossRef] [PubMed]
-
Castro, C.; Smidansky, E.; Maksimchuk, K.R.; Arnold, J.J.; Korneeva, V.S.; Gotte, M.; Konigsberg, W.; Cameron, C.E. Two proton transfers in the transition state for nucleotidyl transfer catalyzed by RNA-and DNA-dependent RNA and DNA polymerases. Proc. Natl. Acad. Sci. USA 2007, 104, 4267-4272. [CrossRef] [PubMed]
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 4267-4272
-
-
Castro, C.1
Smidansky, E.2
Maksimchuk, K.R.3
Arnold, J.J.4
Korneeva, V.S.5
Gotte, M.6
Konigsberg, W.7
Cameron, C.E.8
-
53
-
-
59649110607
-
Nucleic acid polymerases use a general acid for nucleotidyl transfer
-
[CrossRef] [PubMed]
-
Castro, C.; Smidansky, E.D.; Arnold, J.J.; Maksimchuk, K.R.; Moustafa, I.; Uchida, A.; Gotte, M.; Konigsberg, W.; Cameron, C.E. Nucleic acid polymerases use a general acid for nucleotidyl transfer. Nat. Struct. Mol. Biol. 2009, 16, 212-218. [CrossRef] [PubMed]
-
(2009)
Nat. Struct. Mol. Biol
, vol.16
, pp. 212-218
-
-
Castro, C.1
Smidansky, E.D.2
Arnold, J.J.3
Maksimchuk, K.R.4
Moustafa, I.5
Uchida, A.6
Gotte, M.7
Konigsberg, W.8
Cameron, C.E.9
-
54
-
-
84865768433
-
Motif D of viral RNA-dependent RNA polymerases determines efficiency and fidelity of nucleotide addition
-
[CrossRef] [PubMed]
-
Yang, X.; Smidansky, E.D.; Maksimchuk, K.R.; Lum, D.; Welch, J.L.; Arnold, J.J.; Cameron, C.E.; Boehr, D.D. Motif D of viral RNA-dependent RNA polymerases determines efficiency and fidelity of nucleotide addition. Structure 2012, 20, 1519-1527. [CrossRef] [PubMed]
-
(2012)
Structure
, vol.20
, pp. 1519-1527
-
-
Yang, X.1
Smidansky, E.D.2
Maksimchuk, K.R.3
Lum, D.4
Welch, J.L.5
Arnold, J.J.6
Cameron, C.E.7
Boehr, D.D.8
-
55
-
-
84865279748
-
Coxsackievirus B3 mutator strains are attenuated in vivo
-
[CrossRef] [PubMed]
-
Gnädig, N.F.; Beaucourt, S.; Campagnola, G.; Bordería, A.V.; Sanz-Ramos, M.; Gong, P.; Blanc, H.; Peersen, O.B.; Vignuzzi, M. Coxsackievirus B3 mutator strains are attenuated in vivo. Proc. Natl. Acad. Sci. USA 2012, 109, E2294-E2303. [CrossRef] [PubMed]
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. E2294-E2303
-
-
Gnädig, N.F.1
Beaucourt, S.2
Campagnola, G.3
Bordería, A.V.4
Sanz-Ramos, M.5
Gong, P.6
Blanc, H.7
Peersen, O.B.8
Vignuzzi, M.9
-
56
-
-
84919427801
-
Structure-function relationships underlying the replication fidelity of viral RNA-dependent RNA polymerases
-
[CrossRef] [PubMed]
-
Campagnola, G.; McDonald, S.; Beaucourt, S.; Vignuzzi, M.; Peersen, O.B. Structure-function relationships underlying the replication fidelity of viral RNA-dependent RNA polymerases. J. Virol. 2015, 89, 275-286. [CrossRef] [PubMed]
-
(2015)
J. Virol
, vol.89
, pp. 275-286
-
-
Campagnola, G.1
McDonald, S.2
Beaucourt, S.3
Vignuzzi, M.4
Peersen, O.B.5
-
57
-
-
84916918593
-
Structure of a backtracked state reveals conformational changes similar to the state following nucleotide incorporation in human norovirus polymerase
-
[CrossRef] [PubMed]
-
Zamyatkin, D.; Rao, C.; Hoffarth, E.; Jurca, G.; Rho, H.; Parra, F.; Grochulski, P.; Ng, K.K. Structure of a backtracked state reveals conformational changes similar to the state following nucleotide incorporation in human norovirus polymerase. Acta Crystallogr. D Biol. Crystallogr. 2014, 70, 3099-3109. [CrossRef] [PubMed]
-
(2014)
Acta Crystallogr. D Biol. Crystallogr
, vol.70
, pp. 3099-3109
-
-
Zamyatkin, D.1
Rao, C.2
Hoffarth, E.3
Jurca, G.4
Rho, H.5
Parra, F.6
Grochulski, P.7
Ng, K.K.8
-
58
-
-
0026783262
-
Point mutations which drastically affect the polymerization activity of encephalomyocarditis virus RNA-dependent RNA polymerase correspond to the active site of Escherichia coli DNA polymerase I
-
[PubMed]
-
Sankar, S.; Porter, A.G. Point mutations which drastically affect the polymerization activity of encephalomyocarditis virus RNA-dependent RNA polymerase correspond to the active site of Escherichia coli DNA polymerase I. J. Biol. Chem. 1992, 267, 10168-10176. [PubMed]
-
(1992)
J. Biol. Chem
, vol.267
, pp. 10168-10176
-
-
Sankar, S.1
Porter, A.G.2
-
59
-
-
84895920030
-
The ins and outs of viral RNA polymerase translocation
-
[CrossRef] [PubMed]
-
Boehr, D.D. The ins and outs of viral RNA polymerase translocation. J. Mol. Biol. 2014, 426, 1373-1376. [CrossRef] [PubMed]
-
(2014)
J. Mol. Biol
, vol.426
, pp. 1373-1376
-
-
Boehr, D.D.1
-
60
-
-
84899093998
-
The crystal structure of a cardiovirus RNA-dependent RNA polymerase reveals an unusual conformation of the polymerase active site
-
[CrossRef] [PubMed]
-
Vives-Adrian, L.; Lujan, C.; Oliva, B.; van der Linden, L.; Selisko, B.; Coutard, B.; Canard, B.; van Kuppeveld, F.J.; Ferrer-Orta, C.; Verdaguer, N. The crystal structure of a cardiovirus RNA-dependent RNA polymerase reveals an unusual conformation of the polymerase active site. J. Virol. 2014, 88, 5595-5607. [CrossRef] [PubMed]
-
(2014)
J. Virol
, vol.88
, pp. 5595-5607
-
-
Vives-Adrian, L.1
Lujan, C.2
Oliva, B.3
van der Linden, L.4
Selisko, B.5
Coutard, B.6
Canard, B.7
van Kuppeveld, F.J.8
Ferrer-Orta, C.9
Verdaguer, N.10
-
61
-
-
0029841215
-
Cleavage site mutations in the encephalomyocarditis virus P3 region lethally abrogate the normal processing cascade
-
[PubMed]
-
Hall, D.J.; Palmenberg, A.C. Cleavage site mutations in the encephalomyocarditis virus P3 region lethally abrogate the normal processing cascade. J. Virol. 1996, 70, 5954-5961. [PubMed]
-
(1996)
J. Virol
, vol.70
, pp. 5954-5961
-
-
Hall, D.J.1
Palmenberg, A.C.2
-
62
-
-
84930884570
-
Multifunctionality of a picornavirus polymerase domain: Nuclear localization signal and nucleotide recognition
-
[CrossRef] [PubMed]
-
Ferrer-Orta, C.; de la Higuera, I.; Caridi, F.; Sanchez-Aparicio, M.T.; Moreno, E.; Perales, C.; Singh, K.; Sarafianos, S.G.; Sobrino, F.; Domingo, E.; et al. Multifunctionality of a picornavirus polymerase domain: Nuclear localization signal and nucleotide recognition. J. Virol. 2015, 89, 6848-6859. [CrossRef] [PubMed]
-
(2015)
J. Virol
, vol.89
, pp. 6848-6859
-
-
Ferrer-Orta, C.1
de la Higuera, I.2
Caridi, F.3
Sanchez-Aparicio, M.T.4
Moreno, E.5
Perales, C.6
Singh, K.7
Sarafianos, S.G.8
Sobrino, F.9
Domingo, E.10
-
63
-
-
0031571638
-
Structure of the RNA-dependent RNA polymerase of poliovirus
-
[CrossRef]
-
Hansen, J.L.; Long, A.M.; Schultz, S.C. Structure of the RNA-dependent RNA polymerase of poliovirus. Structure 1997, 5, 1109-1122. [CrossRef]
-
(1997)
Structure
, vol.5
, pp. 1109-1122
-
-
Hansen, J.L.1
Long, A.M.2
Schultz, S.C.3
-
64
-
-
0035283140
-
Oligomeric structures of poliovirus polymerase are important for function
-
[CrossRef] [PubMed]
-
Hobson, S.D.; Rosenblum, E.S.; Richards, O.C.; Richmond, K.; Kirkegaard, K.; Schultz, S.C. Oligomeric structures of poliovirus polymerase are important for function. EMBO J. 2001, 20, 1153-1163. [CrossRef] [PubMed]
-
(2001)
EMBO J
, vol.20
, pp. 1153-1163
-
-
Hobson, S.D.1
Rosenblum, E.S.2
Richards, O.C.3
Richmond, K.4
Kirkegaard, K.5
Schultz, S.C.6
-
65
-
-
0037150679
-
Visualization and functional analysis of RNA-dependent RNA polymerase lattices
-
[CrossRef] [PubMed]
-
Lyle, J.M.; Bullitt, E.; Bienz, K.; Kirkegaard, K. Visualization and functional analysis of RNA-dependent RNA polymerase lattices. Science 2002, 296, 2218-2222. [CrossRef] [PubMed]
-
(2002)
Science
, vol.296
, pp. 2218-2222
-
-
Lyle, J.M.1
Bullitt, E.2
Bienz, K.3
Kirkegaard, K.4
-
66
-
-
75149116259
-
Enzymatic and nonenzymatic functions of viral RNA-dependent RNA polymerases within oligomeric arrays
-
[CrossRef] [PubMed]
-
Spagnolo, J.F.; Rossignol, E.; Bullitt, E.; Kirkegaard, K. Enzymatic and nonenzymatic functions of viral RNA-dependent RNA polymerases within oligomeric arrays. RNA 2010, 16, 382-393. [CrossRef] [PubMed]
-
(2010)
RNA
, vol.16
, pp. 382-393
-
-
Spagnolo, J.F.1
Rossignol, E.2
Bullitt, E.3
Kirkegaard, K.4
-
67
-
-
31644445841
-
Analysis of protein-protein interactions in the feline calicivirus replication complex
-
[CrossRef] [PubMed]
-
Kaiser, W.J.; Chaudhry, Y.; Sosnovtsev, S.V.; Goodfellow, I.G. Analysis of protein-protein interactions in the feline calicivirus replication complex. J. Gen. Virol. 2006, 87, 363-368. [CrossRef] [PubMed]
-
(2006)
J. Gen. Virol
, vol.87
, pp. 363-368
-
-
Kaiser, W.J.1
Chaudhry, Y.2
Sosnovtsev, S.V.3
Goodfellow, I.G.4
-
68
-
-
0033989278
-
De novo initiation of RNA synthesis by the RNA-dependent RNA polymerase (NS5B) of hepatitis C virus
-
[CrossRef] [PubMed]
-
Luo, G.; Hamatake, R.K.; Mathis, D.M.; Racela, J.; Rigat, K.L.; Lemm, J.; Colonno, R.J. De novo initiation of RNA synthesis by the RNA-dependent RNA polymerase (NS5B) of hepatitis C virus. J. Virol. 2000, 74, 851-863. [CrossRef] [PubMed]
-
(2000)
J. Virol
, vol.74
, pp. 851-863
-
-
Luo, G.1
Hamatake, R.K.2
Mathis, D.M.3
Racela, J.4
Rigat, K.L.5
Lemm, J.6
Colonno, R.J.7
-
69
-
-
77952710499
-
Regulation of de novo-initiated RNA synthesis in hepatitis C virus RNA-dependent RNA polymerase by intermolecular interactions
-
[CrossRef] [PubMed]
-
Chinnaswamy, S.; Murali, A.; Li, P.; Fujisaki, K.; Kao, C.C. Regulation of de novo-initiated RNA synthesis in hepatitis C virus RNA-dependent RNA polymerase by intermolecular interactions. J. Virol. 2010, 84, 5923-5935. [CrossRef] [PubMed]
-
(2010)
J. Virol
, vol.84
, pp. 5923-5935
-
-
Chinnaswamy, S.1
Murali, A.2
Li, P.3
Fujisaki, K.4
Kao, C.C.5
-
70
-
-
62749135049
-
The active form of the norovirus RNA-dependent RNA polymerase is a homodimer with cooperative activity
-
[CrossRef] [PubMed]
-
Hogbom, M.; Jager, K.; Robel, I.; Unge, T.; Rohayem, J. The active form of the norovirus RNA-dependent RNA polymerase is a homodimer with cooperative activity. J. Gen. Virol. 2009, 90, 281-291. [CrossRef] [PubMed]
-
(2009)
J. Gen. Virol
, vol.90
, pp. 281-291
-
-
Hogbom, M.1
Jager, K.2
Robel, I.3
Unge, T.4
Rohayem, J.5
-
71
-
-
84884362039
-
The RNA-dependent RNA polymerase of Citrus tristeza virus forms oligomers
-
[CrossRef] [PubMed]
-
Cevik, B. The RNA-dependent RNA polymerase of Citrus tristeza virus forms oligomers. Virology 2013, 447, 121-130. [CrossRef] [PubMed]
-
(2013)
Virology
, vol.447
, pp. 121-130
-
-
Cevik, B.1
-
73
-
-
84924029463
-
Cryo-EM structure of influenza virus RNA polymerase complex at 4.3 Å resolution
-
[CrossRef] [PubMed]
-
Chang, S.; Sun, D.; Liang, H.; Wang, J.; Li, J.; Guo, L.; Wang, X.; Guan, C.; Boruah, B.M.; Yuan, L.; et al. Cryo-EM structure of influenza virus RNA polymerase complex at 4.3 Å resolution. Mol. Cell 2015, 57, 925-935. [CrossRef] [PubMed]
-
(2015)
Mol. Cell
, vol.57
, pp. 925-935
-
-
Chang, S.1
Sun, D.2
Liang, H.3
Wang, J.4
Li, J.5
Guo, L.6
Wang, X.7
Guan, C.8
Boruah, B.M.9
Yuan, L.10
-
74
-
-
79959856127
-
The N-terminus of the RNA polymerase from infectious pancreatic necrosis virus is the determinant of genome attachment
-
[CrossRef] [PubMed]
-
Graham, S.C.; Sarin, L.P.; Bahar, M.W.; Myers, R.A.; Stuart, D.I.; Bamford, D.H.; Grimes, J.M. The N-terminus of the RNA polymerase from infectious pancreatic necrosis virus is the determinant of genome attachment. PLoS Pathog. 2011, 7, e1002085. [CrossRef] [PubMed]
-
(2011)
PLoS Pathog
, vol.7
-
-
Graham, S.C.1
Sarin, L.P.2
Bahar, M.W.3
Myers, R.A.4
Stuart, D.I.5
Bamford, D.H.6
Grimes, J.M.7
-
75
-
-
0036940179
-
Different substitutions at conserved amino acids in domains II and III in the Sendai L RNA polymerase protein inactivate viral RNA synthesis
-
[CrossRef] [PubMed]
-
Smallwood, S.; Hovel, T.; Neubert, W.J.; Moyer, S.A. Different substitutions at conserved amino acids in domains II and III in the Sendai L RNA polymerase protein inactivate viral RNA synthesis. Virology 2002, 304, 135-145. [CrossRef] [PubMed]
-
(2002)
Virology
, vol.304
, pp. 135-145
-
-
Smallwood, S.1
Hovel, T.2
Neubert, W.J.3
Moyer, S.A.4
-
76
-
-
72849150471
-
Rift valley fever virus L protein forms a biologically active oligomer
-
[CrossRef] [PubMed]
-
Zamoto-Niikura, A.; Terasaki, K.; Ikegami, T.; Peters, C.J.; Makino, S. Rift valley fever virus L protein forms a biologically active oligomer. J. Virol. 2009, 83, 12779-12789. [CrossRef] [PubMed]
-
(2009)
J. Virol
, vol.83
, pp. 12779-12789
-
-
Zamoto-Niikura, A.1
Terasaki, K.2
Ikegami, T.3
Peters, C.J.4
Makino, S.5
-
77
-
-
80052964605
-
Interstitial contacts in an RNA-dependent RNA polymerase lattice
-
[CrossRef] [PubMed]
-
Tellez, A.B.; Wang, J.; Tanner, E.J.; Spagnolo, J.F.; Kirkegaard, K.; Bullitt, E. Interstitial contacts in an RNA-dependent RNA polymerase lattice. J. Mol. Biol. 2011, 412, 737-750. [CrossRef] [PubMed]
-
(2011)
J. Mol. Biol
, vol.412
, pp. 737-750
-
-
Tellez, A.B.1
Wang, J.2
Tanner, E.J.3
Spagnolo, J.F.4
Kirkegaard, K.5
Bullitt, E.6
-
78
-
-
84879554368
-
Surface for catalysis by poliovirus RNA-dependent RNA polymerase
-
[CrossRef] [PubMed]
-
Wang, J.; Lyle, J.M.; Bullitt, E. Surface for catalysis by poliovirus RNA-dependent RNA polymerase. J. Mol. Biol. 2013, 425, 2529-2540. [CrossRef] [PubMed]
-
(2013)
J. Mol. Biol
, vol.425
, pp. 2529-2540
-
-
Wang, J.1
Lyle, J.M.2
Bullitt, E.3
-
79
-
-
79952170633
-
Inhibitors of the hepatitis C virus RNA-dependent RNA polymerase NS5B
-
[CrossRef] [PubMed]
-
Powdrill, M.H.; Bernatchez, J.A.; Gotte, M. Inhibitors of the hepatitis C virus RNA-dependent RNA polymerase NS5B. Viruses 2010, 2, 2169-2195. [CrossRef] [PubMed]
-
(2010)
Viruses
, vol.2
, pp. 2169-2195
-
-
Powdrill, M.H.1
Bernatchez, J.A.2
Gotte, M.3
-
80
-
-
84907050326
-
GS-9669: A novel non-nucleoside inhibitor of viral polymerase for the treatment of hepatitis C virus infection
-
[CrossRef] [PubMed]
-
Gentile, I.; Buonomo, A.R.; Zappulo, E.; Coppola, N.; Borgia, G. GS-9669: A novel non-nucleoside inhibitor of viral polymerase for the treatment of hepatitis C virus infection. Expert Rev. Anti-Infect. Ther. 2014, 12, 1179-1186. [CrossRef] [PubMed]
-
(2014)
Expert Rev. Anti-Infect. Ther
, vol.12
, pp. 1179-1186
-
-
Gentile, I.1
Buonomo, A.R.2
Zappulo, E.3
Coppola, N.4
Borgia, G.5
-
81
-
-
84895822138
-
Polymerases of hepatitis C viruses and flaviviruses: Structural and mechanistic insights and drug development
-
[CrossRef] [PubMed]
-
Caillet-Saguy, C.; Lim, S.P.; Shi, P.Y.; Lescar, J.; Bressanelli, S. Polymerases of hepatitis C viruses and flaviviruses: Structural and mechanistic insights and drug development. Antivir. Res. 2014, 105, 8-16. [CrossRef] [PubMed]
-
(2014)
Antivir. Res
, vol.105
, pp. 8-16
-
-
Caillet-Saguy, C.1
Lim, S.P.2
Shi, P.Y.3
Lescar, J.4
Bressanelli, S.5
-
82
-
-
84901268195
-
Nonnucleoside inhibitors of norovirus RNA polymerase: Scaffolds for rational drug design
-
[CrossRef] [PubMed]
-
Eltahla, A.A.; Lim, K.L.; Eden, J.S.; Kelly, A.G.; Mackenzie, J.M.; White, P.A. Nonnucleoside inhibitors of norovirus RNA polymerase: Scaffolds for rational drug design. Antimicrob. Agents Chemother. 2014, 58, 3115-3123. [CrossRef] [PubMed]
-
(2014)
Antimicrob. Agents Chemother
, vol.58
, pp. 3115-3123
-
-
Eltahla, A.A.1
Lim, K.L.2
Eden, J.S.3
Kelly, A.G.4
Mackenzie, J.M.5
White, P.A.6
-
83
-
-
33845347862
-
In vitro tests to evaluate immunotoxicity: A preliminary study
-
[CrossRef] [PubMed]
-
Carfi, M.; Gennari, A.; Malerba, I.; Corsini, E.; Pallardy, M.; Pieters, R.; van Loveren, H.; Vohr, H.W.; Hartung, T.; Gribaldo, L. In vitro tests to evaluate immunotoxicity: A preliminary study. Toxicology 2007, 229, 11-22. [CrossRef] [PubMed]
-
(2007)
Toxicology
, vol.229
, pp. 11-22
-
-
Carfi, M.1
Gennari, A.2
Malerba, I.3
Corsini, E.4
Pallardy, M.5
Pieters, R.6
van Loveren, H.7
Vohr, H.W.8
Hartung, T.9
Gribaldo, L.10
-
84
-
-
61549128714
-
Antiviral agents acting as DNA or RNA chain terminators
-
[PubMed]
-
De Clercq, E.; Neyts, J. Antiviral agents acting as DNA or RNA chain terminators. Handb. Exp. Pharmacol. 2009, 189, 53-84. [PubMed]
-
(2009)
Handb. Exp. Pharmacol
, vol.189
, pp. 53-84
-
-
De Clercq, E.1
Neyts, J.2
-
85
-
-
11844256382
-
Virus entry into error catastrophe as a new antiviral strategy
-
[CrossRef]
-
Domingo, E. Virus entry into error catastrophe as a new antiviral strategy. Virus Res. 2005, 107, 115-228. [CrossRef]
-
(2005)
Virus Res
, vol.107
, pp. 115-228
-
-
Domingo, E.1
-
86
-
-
0037367315
-
Approaching a new era for hepatitis C virus therapy: Inhibitors of the NS3-4A serine protease and the NS5B RNA-dependent RNA polymerase
-
[CrossRef]
-
De Francesco, R.; Tomei, L.; Altamura, S.; Summa, V.; Migliaccio, G. Approaching a new era for hepatitis C virus therapy: Inhibitors of the NS3-4A serine protease and the NS5B RNA-dependent RNA polymerase. Antivir. Res. 2003, 58, 1-16. [CrossRef]
-
(2003)
Antivir. Res
, vol.58
, pp. 1-16
-
-
De Francesco, R.1
Tomei, L.2
Altamura, S.3
Summa, V.4
Migliaccio, G.5
-
87
-
-
33745886251
-
Non-nucleoside inhibitors binding to hepatitis C virus NS5B polymerase reveal a novel mechanism of inhibition
-
[CrossRef] [PubMed]
-
Biswal, B.K.; Wang, M.; Cherney, M.M.; Chan, L.; Yannopoulos, C.G.; Bilimoria, D.; Bedard, J.; James, M.N. Non-nucleoside inhibitors binding to hepatitis C virus NS5B polymerase reveal a novel mechanism of inhibition. J. Mol. Biol. 2006, 361, 33-45. [CrossRef] [PubMed]
-
(2006)
J. Mol. Biol
, vol.361
, pp. 33-45
-
-
Biswal, B.K.1
Wang, M.2
Cherney, M.M.3
Chan, L.4
Yannopoulos, C.G.5
Bilimoria, D.6
Bedard, J.7
James, M.N.8
-
88
-
-
33645966527
-
A novel, highly selective inhibitor of pestivirus replication that targets the viral RNA-dependent RNA polymerase
-
[CrossRef] [PubMed]
-
Paeshuyse, J.; Leyssen, P.; Mabery, E.; Boddeker, N.; Vrancken, R.; Froeyen, M.; Ansari, I.H.; Dutartre, H.; Rozenski, J.; Gil, L.H.; et al. A novel, highly selective inhibitor of pestivirus replication that targets the viral RNA-dependent RNA polymerase. J. Virol. 2006, 80, 149-160. [CrossRef] [PubMed]
-
(2006)
J. Virol
, vol.80
, pp. 149-160
-
-
Paeshuyse, J.1
Leyssen, P.2
Mabery, E.3
Boddeker, N.4
Vrancken, R.5
Froeyen, M.6
Ansari, I.H.7
Dutartre, H.8
Rozenski, J.9
Gil, L.H.10
-
89
-
-
35148835624
-
The imidazopyrrolopyridine analogue AG110 is a novel, highly selective inhibitor of pestiviruses that targets the viral RNA-dependent RNA polymerase at a hot spot for inhibition of viral replication
-
[CrossRef] [PubMed]
-
Paeshuyse, J.; Chezal, J.M.; Froeyen, M.; Leyssen, P.; Dutartre, H.; Vrancken, R.; Canard, B.; Letellier, C.; Li, T.; Mittendorfer, H.; et al. The imidazopyrrolopyridine analogue AG110 is a novel, highly selective inhibitor of pestiviruses that targets the viral RNA-dependent RNA polymerase at a hot spot for inhibition of viral replication. J. Virol. 2007, 81, 11046-11053. [CrossRef] [PubMed]
-
(2007)
J. Virol
, vol.81
, pp. 11046-11053
-
-
Paeshuyse, J.1
Chezal, J.M.2
Froeyen, M.3
Leyssen, P.4
Dutartre, H.5
Vrancken, R.6
Canard, B.7
Letellier, C.8
Li, T.9
Mittendorfer, H.10
-
90
-
-
84926472896
-
The RNA template channel of the RNA-dependent RNA polymerase as a target for development of antiviral therapy of multiple genera within a virus family
-
[CrossRef] [PubMed]
-
Van der Linden, L.; Vives-Adrián, L.; Selisko, B.; Ferrer-Orta, C.; Liu, X.; Lanke, K.; Ulferts, R.; de Palma, A.M.; Tanchis, F.; Goris, N.; et al. The RNA template channel of the RNA-dependent RNA polymerase as a target for development of antiviral therapy of multiple genera within a virus family. PLoS Pathog. 2015, 23, e1004733. [CrossRef] [PubMed]
-
(2015)
PLoS Pathog
, vol.23
-
-
Van der Linden, L.1
Vives-Adrián, L.2
Selisko, B.3
Ferrer-Orta, C.4
Liu, X.5
Lanke, K.6
Ulferts, R.7
de Palma, A.M.8
Tanchis, F.9
Goris, N.10
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