The crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase in complex with its protein primer VPg confirms the existence of a second VPg binding site on Picornaviridae polymerases

Journal of Virology

Volumn 82, Issue 19, 2008, Pages 9577-9590

  Gruez, Arnaud ^a,d   Selisko, Barbara ^a   Roberts, Michael ^b   Bricogne, Gérard ^b   Bussetta, Cécile ^a   Jabafi, Ilham ^a   Coutard, Bruno ^a   De Palma, Armando M ^c   Neyts, Johan ^c   Canard, Bruno ^a  

^a Centre National de la Recherche Scientifique   (France)

^b GLOBAL PHASING LTD   (United Kingdom)

^c REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

^d Biopôle de l Université de Lorraine   (France)

Author keywords

[No Author keywords available]

Indexed keywords

PYROPHOSPHATE; RNA DIRECTED RNA POLYMERASE; UNCLASSIFIED DRUG; VIRUS PROTEIN; VPG PROTEIN;

ARTICLE; BINDING SITE; COXSACKIE VIRUS B; NUCLEOTIDE SEQUENCE; PICORNAVIRUS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN STRUCTURE; STRUCTURE ANALYSIS; VIRUS REPLICATION;

AMINO ACID SEQUENCE; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; DIPHOSPHATES; ENTEROVIRUS; GENOME, VIRAL; GUANOSINE TRIPHOSPHATE; MOLECULAR CONFORMATION; MOLECULAR SEQUENCE DATA; PEPTIDES; PICORNAVIRIDAE; PROTEIN BINDING; RNA REPLICASE; SEQUENCE HOMOLOGY, AMINO ACID; VIRUS REPLICATION;

COXSACKIEVIRUS; FOOT-AND-MOUTH DISEASE VIRUS; PICORNAVIRIDAE; POLIOVIRUS; RNA VIRUSES;

EID: 52649173300     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.00631-08     Document Type: Article

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