Crystal structure of enterovirus 71 RNA-dependent RNA polymerase complexed with its protein primer VPg: Implication for a trans mechanism of VPg uridylylation

Journal of Virology

Volumn 87, Issue 10, 2013, Pages 5755-5768

  Chen, Cheng ^a   Wang, Yaxin ^b   Shan, Chao ^c   Sun, Yuna ^b   Xu, Peng ^a   Zhou, Honggang ^d,e   Yang, Cheng ^d,e   Shi, Pei Yong ^f   Rao, Zihe ^a,b,f   Zhang, Bo ^c   Lou, Zhiyong ^a  

^a TSINGHUA UNIVERSITY   (China)

^b INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

^c WUHAN INSTITUTE OF VIROLOGY   (China)

^d Tianjin Joint Academy of Biomedicine and Technology   (China)

^e NANKAI UNIVERSITY   (China)

^f WADSWORTH CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENTEROVIRUS 71 PROTEIN; RNA DIRECTED RNA POLYMERASE; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ARTICLE; BINDING AFFINITY; BINDING SITE; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENTEROVIRUS 71; ENZYME ACTIVITY; HYDROGEN BOND; MUTATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN RNA BINDING; PROTEIN SYNTHESIS; STRUCTURE ANALYSIS; VIRUS GENOME; VIRUS REPLICATION;

ANIMALS; CERCOPITHECUS AETHIOPS; CRYSTALLOGRAPHY, X-RAY; ENTEROVIRUS A, HUMAN; MUTAGENESIS, SITE-DIRECTED; MUTANT PROTEINS; PROTEIN BINDING; PROTEIN STRUCTURE, QUATERNARY; RNA REPLICASE; TYROSINE; URIDINE MONOPHOSPHATE; VERO CELLS; VIRAL PROTEINS;

EID: 84877616491     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.02733-12     Document Type: Article

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